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Comparison of Hemorrhagic & Ischemic Stroke Among Blacks and Whites

Award Number: R01NS030678
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Comparison of Hemorrhagic & Ischemic Stroke Among Blacks and Whites - PROJECT SUMMARY: We seek to continue our population-based study of stroke incidence and case fatality, prevalence of risk factors, stroke treatment, and post-stroke outcomes within a biracial metropolitan population of 1,368,604 of whom 223,417 (16.3%) are of black race (US Census 2010). We expect to identify ~4500 physician confirmed and well characterized stroke events (projected 2900 ischemic strokes, 525 hemorrhagic strokes, and 1075 transient ischemic attack [TIA]) among residents of the five-county Greater Cincinnati/Northern Kentucky (GCNK) region at all 20 regional hospitals/EDs for the period 7/1/2019 to 12/31/2020, as well as 2,000 survey participants. For almost 25 years, we have studied trends in stroke incidence and case fatality and have demonstrated a racial disparity where stroke incidence in African-Americans is more than double that of whites. In each prior study period, we have also examined the prevalence of risk factors (and knowledge of stroke) via a population survey in order to put our temporal trend findings into context. In addition to continuing these important activities, we also examined stroke recurrence in a population- based fashion in our prior study period, finding that blacks were more likely to have recurrent events than whites. We now seek to evaluate temporal trends in recurrence rates, and specifically racial disparities in those temporal trends. Previously we had piloted methods of obtaining a population-based outcome among stroke patients, and we are now ready to obtain outcomes after ischemic stroke across our entire population, data that are desperately needed in the field. Finally, we have used our data to inform eligibility for stroke clinical trials via a close collaboration with NIH StrokeNet and have shared our data with the scientific community for this purpose. By obtaining more detailed outcomes data, we will now be able to better inform proposed recovery and prevention trials as well.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $1,408,029 )
2024	2024	CINCINNATI UNIV OF	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	30	6/17/2024	NON-COMPETING CONTINUATION	$1,408,029
2024	2023	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	29	4/29/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,408,029

Issue Date FY: 2023 ( Subtotal = $1,459,880 )
2023	2023	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	29	6/13/2023	NON-COMPETING CONTINUATION	$1,459,880
														Subtotal = $1,459,880

Issue Date FY: 2022 ( Subtotal = $1,451,780 )
2022	2022	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	28	9/9/2022	NON-COMPETING CONTINUATION	$0
2022	2022	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	28	5/27/2022	NON-COMPETING CONTINUATION	$1,451,780
														Subtotal = $1,451,780

Issue Date FY: 2021 ( Subtotal = $1,539,047 )
2021	2021	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	003	27	9/23/2021	NON-COMPETING CONTINUATION	$0
2021	2021	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	27	8/5/2021	NON-COMPETING CONTINUATION	$1,539,047
2021	2020	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	26	3/9/2021	COMPETING CONTINUATION	$1,005,837
2021	2019	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	25	3/9/2021	NON-COMPETING CONTINUATION	-$1,005,837
														Subtotal = $1,539,047

Issue Date FY: 2020 ( Subtotal = $1,564,515 )
2020	2020	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	26	9/18/2020	COMPETING CONTINUATION	$1,564,515
2020	2020	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	26	9/22/2020	COMPETING CONTINUATION	$0
														Subtotal = $1,564,515

Issue Date FY: 2019 ( Subtotal = $1,419,626 )
2019	2019	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	25	3/5/2019	NON-COMPETING CONTINUATION	$1,419,626
														Subtotal = $1,419,626

Issue Date FY: 2018 ( Subtotal = $1,450,842 )
2018	2018	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	24	3/21/2018	NON-COMPETING CONTINUATION	$1,305,758
2018	2018	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	24	5/8/2018	NON-COMPETING CONTINUATION	$145,084
														Subtotal = $1,450,842

Issue Date FY: 2017 ( Subtotal = $1,536,785 )
2017	2017	UNIVERSITY OF CINCINNATI	2600 CLIFTON AVE	CINCINNATI	OH	45220	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	23	3/8/2017	NON-COMPETING CONTINUATION	$1,536,785
														Subtotal = $1,536,785

Issue Date FY: 2016 ( Subtotal = $1,572,253 )
2016	2016	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	22	2/11/2016	NON-COMPETING CONTINUATION	$1,572,253
2016	2015	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	452210225	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	21	3/17/2016	COMPETING CONTINUATION	$0
														Subtotal = $1,572,253

Issue Date FY: 2015 ( Subtotal = $1,599,356 )
2015	2015	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	21	3/16/2015	COMPETING CONTINUATION	$1,599,356
2015	2013	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	20	3/12/2015	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,599,356

Issue Date FY: 2013 ( Subtotal = $985,516 )
2013	2013	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	20	9/4/2013	NON-COMPETING CONTINUATION	$985,516
														Subtotal = $985,516

Issue Date FY: 2012 ( Subtotal = $1,171,044 )
2012	2012	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	19	8/10/2012	SUPPLEMENT FOR EXPANSION	$136,895
2012	2012	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	19	7/12/2012	NON-COMPETING CONTINUATION	$1,034,149
														Subtotal = $1,171,044

Issue Date FY: 2011 ( Subtotal = $1,188,109 )
2011	2011	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	18	7/20/2011	NON-COMPETING CONTINUATION	$1,188,109
														Subtotal = $1,188,109

Issue Date FY: 2010 ( Subtotal = $1,296,789 )
2010	2010	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	17	6/4/2010	NON-COMPETING CONTINUATION	$1,296,789
2010	2009	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	16	6/2/2010	COMPETING CONTINUATION	$0
														Subtotal = $1,296,789

Issue Date FY: 2009 ( Subtotal = $1,281,772 )
2009	2009	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	16	7/3/2009	COMPETING CONTINUATION	$1,281,772
2009	2008	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	15	6/29/2009	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,281,772

Issue Date FY: 2008 ( Subtotal = $765,093 )
2008	2008	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	15	6/17/2008	NON-COMPETING CONTINUATION	$765,093
														Subtotal = $765,093

Issue Date FY: 2007 ( Subtotal = $812,672 )
2007	2007	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	14	6/7/2007	NON-COMPETING CONTINUATION	$812,672
														Subtotal = $812,672

Issue Date FY: 2006 ( Subtotal = $648,975 )
2006	2006	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	13	7/24/2006	NON-COMPETING CONTINUATION	$648,975
														Subtotal = $648,975

Issue Date FY: 2005 ( Subtotal = $1,155,952 )
2005	2005	UNIVERSITY OF CINCINNATI	PO BOX 210225	CINCINNATI	OH	45221	HAMILTON	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	12	5/26/2005	NON-COMPETING CONTINUATION	$1,155,952
														Subtotal = $1,155,952

Grand Total All Awards = $27,902,075

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Comparison of Hemorrhagic & Ischemic Stroke Among Blacks and Whites

Award Number: R01NS030678

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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