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Solutions for Organizing, Sharing and Making Discoveries from iEEG Data

Award Number: R01MH133717
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/18/2024
PERIOD OF PERFORMANCE END DATE: 05/31/2027

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Solutions for Organizing, Sharing and Making Discoveries from iEEG Data - Project Summary/Abstract Direct recording of neural activity from the human brain using implanted electrodes (intracranial EEG, iEEG) is a fast-growing and high-impact technique in human neuroscience. The NIH has mandated data sharing plans, but useful sharing that promotes neuroscience discoveries from archival datasets faces many obstacles. One obstacle is difficulties in creating shareable iEEG datasets. In Aim 1, we will create new tools based on the iEEG-BIDS standard, created in 2019 to promote sharing by providing specifications for iEEG datasets. Aim 1A will create an iEEG-BIDS compliant solution for anatomical iEEG data, localizing electrodes using the pre-operative MRI and post-operative CT scans. Aim 1B will create an iEEG-BIDS compliant solution for functional iEEG data, the voltage by time data collected from each electrode as a measure of neural activity. Aim 2 will address the problem that it is currently very difficult for iEEG investigators to share the results of their iEEG analyses, and difficult for other scientists to explore them. A new tool will merge an advanced 3D Viewer designed for iEEG with the output of an investigator's existing anatomical and functional iEEG pipelines. The tool will export a single, compact package that can be shared directly with other scientists or uploaded to journals or an archive. By simply opening the package in a web browser, users will be able to interactively explore the dataset, facilitating replication, reliability, and new discoveries.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $411,064 )
2026	2026	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Mental Health Research Grants	000	3	5/26/2026	NON-COMPETING CONTINUATION	$411,064
														Subtotal = $411,064

Issue Date FY: 2025 ( Subtotal = $411,064 )
2025	2025	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Mental Health Research Grants	001	2	6/28/2025	NON-COMPETING CONTINUATION	$0
2025	2025	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Mental Health Research Grants	000	2	6/24/2025	NON-COMPETING CONTINUATION	$411,064
														Subtotal = $411,064

Issue Date FY: 2024 ( Subtotal = $465,512 )
2024	2024	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE	3451 WALNUT ST STE 440A	PHILADELPHIA	PA	19104	PHILADELPHIA	USA	Mental Health Research Grants	000	1	7/18/2024	NEW	$465,512
														Subtotal = $465,512

Grand Total All Awards = $1,287,640

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Solutions for Organizing, Sharing and Making Discoveries from iEEG Data

Award Number: R01MH133717

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/18/2024

PERIOD OF PERFORMANCE END DATE: 05/31/2027

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