Monday, December 15, 2025 12/15/2025

Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young people with HIV

Award Number: R01MD019185
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/24/2023
PERIOD OF PERFORMANCE END DATE: 11/30/2028

Group Awards By:

View Award Description

Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young people with HIV - Modified Project Summary/Abstract Section The Positive Peers mobile app is an original platform developed by and for the hardest to reach HIV population, young people with HIV (YPWH). This app holds potential to provide extensive, customizable, self-management tools (i.e., wellness tracker, community forum, chat, frequent original blogs) to young people with HIV anywhere in the US. The Positive Peers app provides health information, health management tools and virtual community support. While the app itself offers a confidential place for young people with HIV to get health information and support, its use is enhanced by the presence of local peer administrators who provide navigation, support and coaching to users. The proposed study seeks to evaluate its effectiveness in improving viral suppression among younger populations, 13-34 years of age who are either newly diagnosed, out of care or not virally suppressed using a randomized control trial design supplemented by an observational cohort of persons who decline to use the app. Clinics in six high priority Ending the HIV Epidemic jurisdictions will train staff as app administrators and utilize the app as a clinic-based tool. Our primary objective is to improve HIV outcomes by offering peer interaction, targeted retention and adherence messaging, and interactive trackers and reminders in one smartphone app. Our specific aims are: Aim 1: Compare the effectiveness of HIV care supported by the PPA to usual care for retention in HIV care and viral suppression of newly diagnosed or re-engaged high priority younger adults with HIV. Aim 2: To identify factors that predict user engagement with primary PPA components and associated effects on retention in care, viral suppression, and HIV related perceived stigma. Aim 3: To determine intervention adoption, usability, fidelity, and cost across study sites. These aims will be addressed in a parallel cohort design randomized controlled trial of 250 newly diagnosed or out of care YPWH from designated high priority sites. Participants will be allocated 1:1 to receive the PPA app upon study entry or to a delayed intervention arm where they will receive the usual care with attention controls for 6 months. This will allow for effectiveness evaluation during the earliest phase of adjustment to the diagnosis while also allowing for longitudinal outcome effects.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $1,015,306 )
2026	2026	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Minority Health and Health Disparities Research	000	3	12/7/2025	NON-COMPETING CONTINUATION	$1,015,306
														Subtotal = $1,015,306

Issue Date FY: 2025 ( Subtotal = $1,133,269 )
2025	2025	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Minority Health and Health Disparities Research	001	2	7/22/2025	NON-COMPETING CONTINUATION	$113,326
2025	2025	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Minority Health and Health Disparities Research	000	2	11/28/2024	NON-COMPETING CONTINUATION	$1,019,943
														Subtotal = $1,133,269

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Minority Health and Health Disparities Research	001	1	4/8/2024	NEW	$0
2024	2023	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Minority Health and Health Disparities Research	000	1	3/29/2024	NEW	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $1,227,205 )
2023	2023	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Minority Health and Health Disparities Research	001	1	9/26/2023	NEW	$0
2023	2023	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Minority Health and Health Disparities Research	000	1	9/24/2023	NEW	$1,227,205
														Subtotal = $1,227,205

Grand Total All Awards = $3,375,780

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young people with HIV

Award Number: R01MD019185

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/24/2023

PERIOD OF PERFORMANCE END DATE: 11/30/2028

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer