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 | Issue Date FY: 2026 ( Subtotal = $185,950,333 ) (Continued on the next page) |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01GM169393 | DMS/NIGMS 1:Structure-Enhanced Statistical and Machine Learning Methods for Spatial Transcriptomics Cell Type Deconvolution and its Applications | 000 | 1 | NIH | 7/22/2026 | $200,001 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21CA318125 | Photobiomodulation-Enhanced CAR-T Cell Therapy | 000 | 1 | NIH | 7/31/2026 | $393,812 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R25GM161964 | CWRU Postbaccalaureate Research Education Program | 000 | 1 | NIH | 6/10/2026 | $502,792 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AA032476 | Effects of perinatal ethanol exposure on immature respiratory control | 000 | 1 | NIH | 7/22/2026 | $550,442 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30HL178232 | Cardiovascular risk prediction from small, low-densitycalcifications detected on CT calciumscore exams | 000 | 2 | NIH | 9/8/2026 | $55,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21EB039456 | Feasibility of a Novel Freezing of Gait Detection Framework for Adaptive Cueing in Parkinson's Disease | 000 | 1 | NIH | 8/18/2026 | $218,869 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31CA314408 | Defining fatty acid desaturase 2 (FADS2) as a novel therapeutic target in Ewing sarcoma | 001 | 1 | NIH | 5/19/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31CA314408 | Defining fatty acid desaturase 2 (FADS2) as a novel therapeutic target in Ewing sarcoma | 000 | 1 | NIH | 5/19/2026 | $42,696 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG099323 | Uncovering the Therapeutic Potential of Semaglutide in Alzheimer's Disease: Insights from Animal Models and Real-World Clinical Data | 000 | 1 | NIH | 8/13/2026 | $655,673 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21TW013237 | TRI-CARE: Triplex Cellphone Assay for Rapid Evaluation of HIV, HBV and HCV Viral Load | 000 | 1 | NIH | 8/13/2026 | $440,709 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI196274 | Leveraging Large Language Models for the Design of Monoclonal Antibodies Against Malaria | 000 | 1 | NIH | 4/7/2026 | $282,757 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21HD120228 | Endometriosis, the microbiome and innate immunity | 001 | 1 | NIH | 9/15/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21HD120228 | Endometriosis, the microbiome and innate immunity | 000 | 1 | NIH | 8/18/2026 | $235,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DK144830 | Molecular factors controlling vitamin A uptake homeostasis | 000 | 1 | NIH | 8/17/2026 | $551,915 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | RF1AG094791 | Neurovascular Coupling and Waste Clearance in Aging Brain | 000 | 1 | NIH | 7/31/2026 | $3,153,437 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K23AT014015 | Transcutaneous Electrical Acustimulation Synchronized with Natural Breathing for Treatment of Epigastric Pain Syndrome | 000 | 1 | NIH | 7/22/2026 | $189,000 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | U01CA304453 | Mechanisms of regulation of metastasis by cancer extracellular vesicle-activated pathway | 000 | 1 | NIH | 7/9/2026 | $667,575 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI191916 | Investigating Plasma Cell-Free Hemoglobin as a Driver of Cardiovascular Disease Risk in HIV-Positive Individuals | 000 | 1 | NIH | 4/21/2026 | $235,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL184157 | Decision support for ischemia imaging based on AI analysis of low-cost/no-cost screening CT and ECG data | 000 | 1 | NIH | 7/16/2026 | $1,573,126 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R13HG014114 | African Society of Human Geneticsmeeting | 000 | 1 | NIH | 8/27/2026 | $67,101 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01EB037413 | Predicting Efficacy of Nanomedicine Based Chemotherapeutics using Contrast Enhanced Ultrasound | 000 | 1 | NIH | 4/27/2026 | $531,541 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21HL187010 | Plasma Cell-Free Hemoglobin: A Potential Modulator of Immune Dysregulation in HIV | 000 | 1 | NIH | 8/13/2026 | $431,750 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA294611 | MR Fingerprinting for Characterization and Prediction of Glioblastoma Infiltration | 000 | 2 | NIH | 7/15/2026 | $55,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R00NS135194 | Targeted Neuroplasticity via vagus nerve stimulation to improve urinary dysfunction after spinal cord injury | 000 | 3 | NIH | 8/7/2026 | $249,000 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K99HL179260 | Atomic-level Structural-omics of Platelet Membrane Proteins via Multi-scale Structural Biology Approaches | 000 | 2 | NIH | 6/23/2026 | $121,003 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R25CA225461 | Cancer-focused Summer Undergraduate Research (CanSUR) Program | 000 | 9 | NIH | 8/19/2026 | $362,533 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UG1EY037206 | Diabetes Endothelial Keratoplasty Study (DEKS): Impact of Diabetes and Other Predictors on Corneal Transplant Endothelial Cell Loss and Success | 003 | 2 | NIH | 7/8/2026 | $450,364 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K12TR005469 | Clinical and Translational Science Collaborative of Northern Ohio, CTSA K12 Program at Case Western Reserve University | 000 | 2 | NIH | 7/30/2026 | $1,078,928 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UG1EY037206 | Diabetes Endothelial Keratoplasty Study (DEKS): Impact of Diabetes and Other Predictors on Corneal Transplant Endothelial Cell Loss and Success | 002 | 2 | NIH | 6/25/2026 | $752,932 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R00AI173544 | Improving phage-based medicine with immunoengineering | 000 | 4 | NIH | 7/29/2026 | $246,604 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K08AI198077 | Role of myeloid KLF2 in the neonatal innate immune response | 000 | 1 | NIH | 3/27/2026 | $165,240 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG083811 | Role of Mettl3-dependent RNA m6A dysregulation in Alzheimer's disease | 000 | 2 | NIH | 9/16/2026 | $700,897 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AR085665 | Multimodal Treatment for Chronic Pain after Total Knee Arthroplasty | 000 | 1 | NIH | 9/17/2026 | $3,519,366 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HD120332 | Impact of Cancer Therapy on Sperm Mutations Using Sequential Samples | 000 | 1 | NIH | 9/4/2026 | $673,995 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HD120332 | Impact of Cancer Therapy on Sperm Mutations Using Sequential Samples | 001 | 1 | NIH | 9/15/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UG3AG101220 | Repurposing the NMDA Receptor Antagonist Memantine as a Cognitive Enhancer in Stage 0 Alzheimer's Disease in Persons with Down Syndrome | 000 | 1 | NIH | 9/7/2026 | $496,214 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NR022609 | A Randomized Trial of REFRAME: an Emotion Regulation Intervention to Improve Psychological Outcomes in Surrogate Decision-Makers for Survivors of Invasive Mechanical Ventilation | 000 | 1 | NIH | 9/14/2026 | $782,106 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-7015 | CUYAHOGA | USA | T3256074 | NRSA for Primary Medical Care | 00 | 1 | HRSA | 9/11/2026 | $577,077 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AI195257 | Cellular mechanisms promoting early reactivation of latent HIV across clades | 000 | 1 | NIH | 9/11/2026 | $884,647 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | H79SM092331 | Cuyahoga County Youth Work Initiative - Mental Health Awareness Training | 000 | 1 | SAMHSA | 9/16/2026 | $199,533 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | S10OD040144 | Critical Upgrade of 7.0T Preclinical MRI Scanner | 000 | 1 | NIH | 9/14/2026 | $1,899,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HD119005 | Androgen-Estrogen Balance and FGF Pathways: Mechanisms underlying the contribution of efferent ducts to human sperm maturation | 000 | 1 | NIH | 9/2/2026 | $350,286 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG099057 | Mitochondrial Mechanisms in Synucleinopathies | 000 | 1 | NIH | 9/4/2026 | $635,545 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21HD119353 | Kindergarten Readiness Assessment Scores after Having Early-childhood Respiratory failure (KRASHER) | 000 | 1 | NIH | 9/3/2026 | $472,336 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R56AI143694 | Defining targets of protective immunity to Plasmodium vivax using human monoclonal antibodies | 000 | 6 | NIH | 8/25/2026 | $631,401 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31HL189103 | Characterizing Factor XII Thromboinflammatory Functions in Diabetes Mellitus | 000 | 1 | NIH | 8/19/2026 | $50,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL185525 | The "bait and switch" gene therapy for cardiomyopathies | 000 | 1 | NIH | 7/7/2026 | $1,532,398 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21HD122975 | Proteolytic cleavage of PR-B: A novel mechanism for functional progesterone withdrawal in human parturition | 000 | 1 | NIH | 8/21/2026 | $431,750 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AI201547 | Dissecting GBP1-Mediated Immune Responses: From Pathogen Sensing and Defense to Organelle Dynamics | 000 | 1 | NIH | 8/11/2026 | $428,203 |
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