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 | Issue Date FY: 2026 ( Subtotal = $57,824,319 ) (Continued on the next page) |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DC021795 | Calcium Regulation in Cochlear Cells | 000 | 2 | NIH | 1/10/2026 | $575,254 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA287672 | Optimizing anti-wild-type IDH1 therapy in pancreatic cancer | 000 | 3 | NIH | 4/17/2026 | $679,004 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA297621 | Anticancer ELNP nanovaccines for curative treatmentof pancreatic cancer | 001 | 2 | NIH | 4/16/2026 | $65,467 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA297621 | Anticancer ELNP nanovaccines for curative treatmentof pancreatic cancer | 000 | 2 | NIH | 12/10/2025 | $589,214 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA295877 | A Clinical Trial of Cancer Prevention by Biomarker Based Detections of Barrett's Esophagus and Its Progression | 001 | 2 | NIH | 4/16/2026 | $155,648 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA299332 | Creating a transient metabolic catastrophe for AML therapy | 000 | 2 | NIH | 2/27/2026 | $476,107 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA295877 | A Clinical Trial of Cancer Prevention by Biomarker Based Detections of Barrett's Esophagus and Its Progression | 000 | 2 | NIH | 2/24/2026 | $1,400,846 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA297778 | EphA1 homotypic and EphA1-EphA2 heterotypic interactions in cell regulation | 001 | 2 | NIH | 4/16/2026 | $66,276 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA297778 | EphA1 homotypic and EphA1-EphA2 heterotypic interactions in cell regulation | 000 | 2 | NIH | 12/17/2025 | $596,474 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA296150 | Leveraging Community-Based Food Pantry Settings for Provision of Tobacco Cessation Treatment | 001 | 2 | NIH | 4/16/2026 | $66,783 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA296150 | Leveraging Community-Based Food Pantry Settings for Provision of Tobacco Cessation Treatment | 000 | 2 | NIH | 1/30/2026 | $601,066 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AG095389 | CHCHD10 in Tauopathy in AD and ADRD | 000 | 1 | NIH | 12/29/2025 | $431,750 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI191916 | Investigating Plasma Cell-Free Hemoglobin as a Driver of Cardiovascular Disease Risk in HIV-Positive Individuals | 000 | 1 | NIH | 4/21/2026 | $235,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI192237 | CMV reactivation in the vasculature of people with HIV drives T cell responses | 000 | 1 | NIH | 2/20/2026 | $233,790 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI196274 | Leveraging Large Language Models for the Design of Monoclonal Antibodies Against Malaria | 000 | 1 | NIH | 4/7/2026 | $282,757 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS141199 | Regulation of ATAD3A in TDP43-associated ALS/FTD | 000 | 2 | NIH | 4/7/2026 | $586,486 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS141199 | Regulation of ATAD3A in TDP43-associated ALS/FTD | 000 | 2 | NIH | 4/7/2026 | $151,234 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R03DE035522 | An Atlas of Bacterial Physiology in the Human Oral Cavity | 000 | 1 | NIH | 2/4/2026 | $340,149 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS114510 | Genetic Control of Respiratory Motor Circuit Development, Connectivity and Maintenance | 000 | 7 | NIH | 2/24/2026 | $467,814 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS124206 | AQP4 and glymphatic function in post-stroke recovery | 000 | 4 | NIH | 4/7/2026 | $571,925 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS124206 | AQP4 and glymphatic function in post-stroke recovery | 000 | 4 | NIH | 4/7/2026 | $121,317 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS122218 | Deubiquitinase USP19 in TDP-43 pathogenesis. | 000 | 3 | NIH | 5/11/2026 | $595,610 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS129876 | Investigation of brain-originating circRNAs as targets in blood-based stroke triage diagnostics | 000 | 4 | NIH | 3/19/2026 | $627,857 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS128226 | Structural diversity of cervid prions and phenotypic variation of chronic wasting disease | 000 | 4 | NIH | 4/7/2026 | $402,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MH130367 | Long-range GABAergic inhibition coordinates hippocampal-subcortical circuit activity in memory formation | 000 | 4 | NIH | 1/20/2026 | $485,020 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MH129294 | The role of subcortical inputs to the hippocampal CA3 region in fear memory | 000 | 4 | NIH | 12/15/2025 | $394,752 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MH130476 | The role of heparan sulfate modification on neurexin1 in synapse development | 000 | 3 | NIH | 12/19/2025 | $418,262 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MH134316 | Nuclear receptor regulation of epigenetic mechanisms regulating HIV CNS latency | 000 | 4 | NIH | 5/11/2026 | $348,216 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MH134316 | Nuclear receptor regulation of epigenetic mechanisms regulating HIV CNS latency | 000 | 4 | NIH | 5/11/2026 | $364,391 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL176819 | Leveraging HSF1 Attenuation to Transform Clonal Hematopoiesis into Beneficial Hematopoiesis | 001 | 2 | NIH | 3/24/2026 | $21,595 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL176819 | Leveraging HSF1 Attenuation to Transform Clonal Hematopoiesis into Beneficial Hematopoiesis | 000 | 2 | NIH | 2/6/2026 | $683,843 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL177837 | Adverse Effects of Neonatal CPAP on Lung Development | 000 | 2 | NIH | 4/28/2026 | $710,447 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MD019185 | Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young people with HIV | 001 | 3 | NIH | 2/21/2026 | $112,811 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MD019185 | Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young people with HIV | 000 | 3 | NIH | 12/7/2025 | $1,015,306 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL166241 | Engineered polymeric adjuvants for heart-redirected targeting and gene therapy | 000 | 3 | NIH | 5/12/2026 | $582,642 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL167159 | 5 D impulse mapping in the embryonic heart | 001 | 4 | NIH | 4/23/2026 | $20,259 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL167159 | 5 D impulse mapping in the embryonic heart | 000 | 4 | NIH | 3/20/2026 | $641,471 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL173186 | Radiomics-based risk prediction of heart failure using CT calcium score exam | 000 | 2 | NIH | 4/27/2026 | $692,323 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL172894 | S-Nitrosoglutathione therapy for oxidant disease of the neonatal airways and lung | 001 | 3 | NIH | 3/25/2026 | $16,469 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL172894 | S-Nitrosoglutathione therapy for oxidant disease of the neonatal airways and lung | 000 | 3 | NIH | 3/6/2026 | $521,532 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL175803 | Molecular Basis for cMyBP-C HCM variants | 000 | 2 | NIH | 4/28/2026 | $701,205 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL126900 | Restoration and Function of S-Nitrosothiol in Stored Blood | 001 | 9 | NIH | 3/24/2026 | $17,016 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL126900 | Restoration and Function of S-Nitrosothiol in Stored Blood | 000 | 9 | NIH | 2/19/2026 | $538,868 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UM1AI069501 | Case Clinical Trials Unit | 002 | 20 | NIH | 4/15/2026 | $1,301,019 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UM1AI069501 | Case Clinical Trials Unit | 001 | 20 | NIH | 1/26/2026 | $310,250 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UM1AI069501 | Case Clinical Trials Unit | 000 | 20 | NIH | 1/22/2026 | $685,932 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UG1HD040544 | Case Western Reserve University Center of the NICHD MFMU Network | 000 | 27 | NIH | 4/8/2026 | $354,189 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UG1CA233234 | Case Comprehensive Cancer Center NCTN Lead Academic Participating Site | 000 | 7 | NIH | 4/27/2026 | $1,218,418 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UG1HD021364 | NICHD Neonatal Research Network Clinical Center - Case Western Reserve University | 000 | 41 | NIH | 5/12/2026 | $354,200 |
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