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 | Issue Date FY: 2024 ( Subtotal = $7,393,555 ) (Continued on the next page) |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01GM115234 | Regulatory Mechanisms of Glycoprotein Sialylation | 000 | 8 | NIH | 11/14/2023 | $444,585 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA269816 | Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | 000 | 2 | NIH | 11/2/2023 | $601,330 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA269354 | Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and Acidosis | 000 | 2 | NIH | 11/8/2023 | $597,290 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA235152 | Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy | 000 | 6 | NIH | 11/24/2023 | $405,116 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03CA273468 | c-Myc regulation by TGF-beta signaling as a therapeutic target in Osteosarcoma | 000 | 1 | NIH | 11/22/2023 | $80,500 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AI173549 | Structural studies of gasdermin E and its recognition by caspase-3. | 000 | 2 | NIH | 10/25/2023 | $72,450 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 000 | 2 | NIH | 11/1/2023 | $583,710 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG080287 | Reduced allelic dosage of CLP1 attenuates cognitive dysfunction and pathological burden in transgenic mouse models of Alzheimer?s disease | 000 | 2 | NIH | 11/6/2023 | $139,685 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG080175 | Bacterial triggers of neural inflammation. | 000 | 2 | NIH | 11/16/2023 | $144,900 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG077132 | Evaluation of genetic and metabolic markers in the development of urinary urgency incontinence | 000 | 2 | NIH | 11/16/2023 | $74,596 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AG080924 | SSH1-Nrf2 nexus in tipping the balance between degeneration and protection in tauopathies. | 000 | 2 | NIH | 11/15/2023 | $460,922 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AG076051 | Mechanism of white matter pathology in Alzheimer's disease | 000 | 3 | NIH | 11/3/2023 | $546,748 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01NS114120 | Low-frequency stimulation of fiber tracts to control seizures | 000 | 5 | NIH | 11/10/2023 | $293,890 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | K01DK128304 | Using transcriptomics and ex vivo organotypic models to discover mechanisms of APOL1-associated podocytopathies | 000 | 2 | NIH | 11/8/2023 | $130,741 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F31NS122176 | Identifying novel targets and mechanistic role of 8,9 unsaturated sterol accumulation on enhancement of oligodendrocyte formation | 000 | 3 | NIH | 11/22/2023 | $32,650 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | UM1AI069501 | Case Clinical Trials Unit | 000 | 18 | NIH | 11/13/2023 | $333,180 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH130476 | The role of heparan sulfate modification on neurexin1 in synapse development | 000 | 1 | NIH | 11/17/2023 | $376,437 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | UM1AI069501 | Case Clinical Trials Unit | 000 | 18 | NIH | 11/13/2023 | $863,775 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH129294 | The role of subcortical inputs to the hippocampal CA3 region in fear memory | 000 | 2 | NIH | 11/1/2023 | $355,606 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH117643 | Brain serotonin neuron gene regulatory networks and chromatin architecture | 000 | 5 | NIH | 10/17/2023 | $396,097 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL156987 | Impact of microfibril turnover on vascular development and disease | 002 | 3 | NIH | 11/14/2023 | $362,250 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21EB032644 | Background Oriented Schlieren (BOS) Visualization for Evaluation of Risk in Aerosol-Generating Procedures | 000 | 3 | NIH | 11/9/2023 | $170,026 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21AI169561 | Functional genomic characterization of diverse bat innate immune mechanisms | 000 | 2 | NIH | 10/24/2023 | $181,125 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21AG075573 | Targeting 15-PGDH in Age-Related Hematologic Disease | 000 | 2 | NIH | 11/15/2023 | $217,350 |
| | 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01ES033670 | Targets and targeting of immunometabolism in chronic PM2.5 exposure | 000 | 3 | NIH | 11/17/2023 | $402,500 |
| | 2024 | 2023 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01DE026923 | Amphiregulin-Immunometabolism axis in oral immunity and inflammation during HIV infection | 000 | 7 | NIH | 11/17/2023 | $0 |
| | 2024 | 2023 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH134316 | Nuclear receptor regulation of epigenetic mechanisms regulating HIV CNS latency | 000 | 1 | NIH | 10/23/2023 | $0 |
| | 2024 | 2023 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH134316 | Nuclear receptor regulation of epigenetic mechanisms regulating HIV CNS latency | 000 | 1 | NIH | 10/23/2023 | $0 |
| | 2024 | 2023 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | UG3DE030856 | Multi-Level Interventions to Reduce Oral Health Disparities among Adults in Primary Care Settings | 000 | 2 | NIH | 10/13/2023 | $0 |
| | 2024 | 2023 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL156987 | Impact of microfibril turnover on vascular development and disease | 001 | 2 | NIH | 10/23/2023 | $253,491 |
| | 2024 | 2023 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | U01CA271867 | Validation of Biomarkers for predicting Barrett's esophagus that will or will not: i) progress towards cancer, or ii) recur after ablation | 000 | 2 | NIH | 10/20/2023 | $0 |
| | 2024 | 2023 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | T32EY007157 | CWRU-Visual Sciences Training Program | 000 | 22 | NIH | 11/15/2023 | $0 |
| | 2024 | 2022 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30CA239355 | Development of Real-time MR imaging and Visualization System to Improve MR-guided Prostate Biopsy | 000 | 3 | NIH | 10/31/2023 | -$43,088 |
| | 2024 | 2022 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | U01CA248226 | RadxTools for assessing tumor treatment response on imaging | 000 | 3 | NIH | 11/8/2023 | $0 |
| | 2024 | 2022 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL103827 | Targeting Notch2 in Hematopoietic Cell Therapy | 000 | 9 | NIH | 11/8/2023 | -$590,982 |
| | 2024 | 2022 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21CA256573 | Differential Diagnosis of recurrent GBM versus Radiation Necrosis using MDSCbiomarkers | 000 | 2 | NIH | 10/13/2023 | -$14,721 |
| | 2024 | 2021 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R13HG011415 | African Society of Human Genetics (AfSHG) | 000 | 1 | NIH | 11/21/2023 | -$49 |
| | 2024 | 2021 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03HD102452 | Identifying the causal mechanisms of a hospital-based violence intervention program. | 000 | 2 | NIH | 11/6/2023 | $0 |
| | 2024 | 2021 | CASE WESTERN RESERVE UNIVERSITY | 10900 Euclid Ave | Cleveland | OH | 44106-1712 | CUYAHOGA | USA | D4033337 | Graduate Psychology Education Programs | 02 | 3 | HRSA | 10/25/2023 | -$19,648 |
| | 2024 | 2021 | CASE WESTERN RESERVE UNIVERSITY | 10900 Euclid Ave | Cleveland | OH | 44106-1712 | CUYAHOGA | USA | D4033337 | Graduate Psychology Education Programs | 02 | 3 | HRSA | 10/25/2023 | -$58,946 |
| | 2024 | 2021 | CASE WESTERN RESERVE UNIVERSITY | 10900 Euclid Ave | Cleveland | OH | 44106-1712 | CUYAHOGA | USA | D4033337 | Graduate Psychology Education Programs | 01 | 5 | HRSA | 10/26/2023 | $20,006 |
| | 2024 | 2021 | CASE WESTERN RESERVE UNIVERSITY | 10900 Euclid Ave | Cleveland | OH | 44106-1712 | CUYAHOGA | USA | D4033337 | Graduate Psychology Education Programs | 01 | 5 | HRSA | 10/26/2023 | $20,006 |
| | 2024 | 2021 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL139754 | In Vivo Mechanisms of Integrated G protein Signaling Regulation by RGS Proteins | 000 | 4 | NIH | 10/23/2023 | $0 |
| | 2024 | 2021 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01GM126833 | Defining the Structural Mechanisms of RNP Complexes that Regulate Enterovirus Translation | 000 | 4 | NIH | 10/18/2023 | -$102,953 |
| | 2024 | 2021 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21AI148875 | Small molecule inhibitors of lytic transglycosylase to potentiate beta-lactam antibiotics | 000 | 2 | NIH | 11/15/2023 | $0 |
| | 2024 | 2020 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AI116730 | Transcriptional regulation by O-GlcNAcylation in T lymphocytes | 000 | 5 | NIH | 11/10/2023 | $0 |
| | 2024 | 2020 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL133574 | Standardized Monitoring of Cellular Adhesion to Improve Clinical Care in Sickle Cell Disease | 001 | 5 | NIH | 11/21/2023 | -$58,451 |
| | 2024 | 2020 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | 90SI5025 | The Northeast Ohio Regional Spinal Cord Injury Model System | 03 | 5 | ACL | 11/15/2023 | -$105,264 |
| | 2024 | 2020 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL133574 | Standardized Monitoring of Cellular Adhesion to Improve Clinical Care in Sickle Cell Disease | 000 | 5 | NIH | 11/21/2023 | $58,451 |
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