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 | Issue Date FY: 2026 ( Subtotal = $150,898,439 ) (Continued on the next page) |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R00AI173544 | Improving phage-based medicine with immunoengineering | 000 | 4 | NIH | 7/29/2026 | $246,604 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R33NS133212 | Human-iPSC derived neuromuscular junctions as a model for neuromuscular diseases. | 000 | 3 | NIH | 8/7/2026 | $390,007 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | T32TR004521 | Clinical and Translational Science Collaborative of Northern Ohio, CTSA Predoctoral T32 at Case Western Reserve University | 000 | 2 | NIH | 6/25/2026 | $461,705 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UG1EY037206 | Diabetes Endothelial Keratoplasty Study (DEKS): Impact of Diabetes and Other Predictors on Corneal Transplant Endothelial Cell Loss and Success | 003 | 2 | NIH | 7/8/2026 | $450,364 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UG1EY037206 | Diabetes Endothelial Keratoplasty Study (DEKS): Impact of Diabetes and Other Predictors on Corneal Transplant Endothelial Cell Loss and Success | 002 | 2 | NIH | 6/25/2026 | $752,932 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K08AI198077 | Role of myeloid KLF2 in the neonatal innate immune response | 000 | 1 | NIH | 3/27/2026 | $165,240 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01GM166613 | Mechanistic Insight into Conformational Regulation of EphA2: From Structure to Function | 000 | 1 | NIH | 7/30/2026 | $339,787 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI192237 | CMV reactivation in the vasculature of people with HIV drives T cell responses | 001 | 1 | NIH | 8/4/2026 | -$233,790 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31HD121428 | Deciphering the molecular mechanisms governing cell fate transition and lineage commitment by H3K4me1/2 demethylation | 002 | 1 | NIH | 4/1/2026 | $576 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI192237 | CMV reactivation in the vasculature of people with HIV drives T cell responses | 001 | 1 | NIH | 8/4/2026 | $233,790 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31HD121428 | Deciphering the molecular mechanisms governing cell fate transition and lineage commitment by H3K4me1/2 demethylation | 001 | 1 | NIH | 1/29/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31HD121428 | Deciphering the molecular mechanisms governing cell fate transition and lineage commitment by H3K4me1/2 demethylation | 000 | 1 | NIH | 1/29/2026 | $49,538 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI192237 | CMV reactivation in the vasculature of people with HIV drives T cell responses | 000 | 1 | NIH | 2/20/2026 | $233,790 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI200041 | Understanding the impact of human protein coding variation on STING function. | 000 | 1 | NIH | 6/16/2026 | $235,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30MH143340 | Structural and functional basis of 5-HT3R modulation by antidepressants | 001 | 1 | NIH | 7/29/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30MH143340 | Structural and functional basis of 5-HT3R modulation by antidepressants | 000 | 1 | NIH | 7/29/2026 | $55,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R35GM163728 | Mechanisms and Regulation of Mitochondrial Fission in Health and Disease | 000 | 1 | NIH | 7/21/2026 | $270,040 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | RF1NS145403 | External Environmental Determinants of Alzheimers Type Dementias and Mechanisms | 000 | 1 | NIH | 7/14/2026 | $1,884,854 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01EB039066 | COSMIIC tSNIP to Treat Chronic Knee Pain | 000 | 1 | NIH | 7/30/2026 | $3,778,614 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K23AT014015 | Transcutaneous Electrical Acustimulation Synchronized with Natural Breathing for Treatment of Epigastric Pain Syndrome | 000 | 1 | NIH | 7/22/2026 | $189,000 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL184919 | Low-Field Magnetic Resonance Imaging Guided Robotic Catheter System for Ventricular Tachycardia Ablation | 000 | 1 | NIH | 6/10/2026 | $760,476 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01GM169393 | DMS/NIGMS 1:Structure-Enhanced Statistical and Machine Learning Methods for Spatial Transcriptomics Cell Type Deconvolution and its Applications | 000 | 1 | NIH | 7/22/2026 | $200,001 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | RF1AG094791 | Neurovascular Coupling and Waste Clearance in Aging Brain | 000 | 1 | NIH | 7/31/2026 | $3,153,437 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21CA318125 | Photobiomodulation-Enhanced CAR-T Cell Therapy | 000 | 1 | NIH | 7/31/2026 | $393,812 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R35GM161242 | Data-driven modeling of estrogen receptor | 000 | 1 | NIH | 5/5/2026 | $431,750 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG096873 | Modifiers of Tau Seeds in Human Brain | 000 | 1 | NIH | 3/5/2026 | $691,999 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA318437 | Ultrasound-triggered nanobubble gene therapy for prostate cancer radiosensitization | 001 | 1 | NIH | 7/23/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA318437 | Ultrasound-triggered nanobubble gene therapy for prostate cancer radiosensitization | 000 | 1 | NIH | 7/23/2026 | $55,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA310113 | Dynamic Contrast Enhanced- Magnetic Resonance Fingerprinting to Detect Early Response to Neoadjuvant Chemotherapy in Breast Cancer Patient | 001 | 1 | NIH | 7/31/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA310113 | Dynamic Contrast Enhanced- Magnetic Resonance Fingerprinting to Detect Early Response to Neoadjuvant Chemotherapy in Breast Cancer Patient | 000 | 1 | NIH | 7/31/2026 | $55,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AA032476 | Effects of perinatal ethanol exposure on immature respiratory control | 000 | 1 | NIH | 7/22/2026 | $550,442 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R25GM161964 | CWRU Postbaccalaureate Research Education Program | 000 | 1 | NIH | 6/10/2026 | $502,792 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL184474 | Mechanisms of cMyBP-C Mediated Fine-Tuning of Cardiac Contractile Function | 000 | 1 | NIH | 7/14/2026 | $2,741,976 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R35GM165496 | Mechanisms of microbial metabolite signaling to chromatin in cell fate and gene regulation | 000 | 1 | NIH | 7/20/2026 | $349,017 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG096172 | Alzheimer Disease Genetic Analysis to Identify Potential Therapeutic Targets (ADAPTT) | 000 | 1 | NIH | 2/4/2026 | $1,256,627 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA306142 | Enhancing CAR-T solid tumor efficacy with secretory iRGD | 000 | 1 | NIH | 7/30/2026 | $55,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R03DE035522 | An Atlas of Bacterial Physiology in the Human Oral Cavity | 000 | 1 | NIH | 2/4/2026 | $340,149 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA306944 | Theranostic Approaches to Breast Cancer Using Image Guided Surgery and Adjuvant PTT | 000 | 1 | NIH | 3/13/2026 | $630,108 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R25CA225461 | Cancer-focused Summer Undergraduate Research (CanSUR) Program | 000 | 9 | NIH | 8/19/2026 | $362,533 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL167159 | 5 D impulse mapping in the embryonic heart | 001 | 4 | NIH | 4/23/2026 | $20,259 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL167159 | 5 D impulse mapping in the embryonic heart | 000 | 4 | NIH | 3/20/2026 | $641,471 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DA060489 | The impact of poly-substance use on the crosstalk between microglia, astrocytes, and neurons that regulates HIV latency | 001 | 3 | NIH | 7/30/2026 | $708,638 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DA060489 | The impact of poly-substance use on the crosstalk between microglia, astrocytes, and neurons that regulates HIV latency | 001 | 3 | NIH | 7/30/2026 | -$708,638 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DA060489 | The impact of poly-substance use on the crosstalk between microglia, astrocytes, and neurons that regulates HIV latency | 000 | 3 | NIH | 2/26/2026 | $708,638 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA287672 | Optimizing anti-wild-type IDH1 therapy in pancreatic cancer | 000 | 3 | NIH | 4/17/2026 | $679,004 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI191916 | Investigating Plasma Cell-Free Hemoglobin as a Driver of Cardiovascular Disease Risk in HIV-Positive Individuals | 000 | 1 | NIH | 4/21/2026 | $235,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | U01CA304453 | Mechanisms of regulation of metastasis by cancer extracellular vesicle-activated pathway | 000 | 1 | NIH | 7/9/2026 | $667,575 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL184157 | Decision support for ischemia imaging based on AI analysis of low-cost/no-cost screening CT and ECG data | 000 | 1 | NIH | 7/16/2026 | $1,573,126 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01EB037413 | Predicting Efficacy of Nanomedicine Based Chemotherapeutics using Contrast Enhanced Ultrasound | 000 | 1 | NIH | 4/27/2026 | $531,541 |
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