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 | Issue Date FY: 2025 ( Subtotal = $160,403,690 ) (Continued on the next page) |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA246678 | Fluorescence-guided resection of breast tumors using a topically-applied molecular probe | 002 | 6 | NIH | 9/19/2025 | $71,775 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA246678 | Fluorescence-guided resection of breast tumors using a topically-applied molecular probe | 001 | 6 | NIH | 9/17/2025 | $173,991 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K01DK125526 | The Intestinal Mycobiome and IBD | 000 | 5 | NIH | 2/27/2025 | $121,770 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HD117313 | Development of optimal sensory feedback strategies to maximize function after tetraplegia | 000 | 1 | NIH | 7/23/2025 | $618,907 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK128463 | Role of Sam68 in Proinflammatory Signaling | 001 | 4 | NIH | 6/26/2025 | $56,227 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK128463 | Role of Sam68 in Proinflammatory Signaling | 000 | 4 | NIH | 2/20/2025 | $506,054 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R00EY034168 | Nanoparticle-Based Tracking of Retinal Ganglion Cell Transplant | 001 | 3 | NIH | 6/11/2025 | $171 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R00EY034168 | Nanoparticle-Based Tracking of Retinal Ganglion Cell Transplant | 000 | 3 | NIH | 2/25/2025 | $249,000 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F30HD114399 | Investigating the Structural Basis of Human Glycine Receptor Modulation for Neurodevelopmental Disorders | 001 | 2 | NIH | 6/2/2025 | $564 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F30HD114399 | Investigating the Structural Basis of Human Glycine Receptor Modulation for Neurodevelopmental Disorders | 000 | 2 | NIH | 3/7/2025 | $53,974 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA235152 | Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy | 000 | 7 | NIH | 2/12/2025 | $364,605 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA235152 | Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy | 003 | 7 | NIH | 5/28/2025 | $40,510 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | UG1CA233234 | Case Comprehensive Cancer Center NCTN Lead Academic Participating Site | 001 | 6 | NIH | 7/22/2025 | $520,340 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | UG1CA233234 | Case Comprehensive Cancer Center NCTN Lead Academic Participating Site | 000 | 6 | NIH | 3/6/2025 | $892,012 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K08CA276819 | Targeting myeloid cells to increase efficacy of immunotherapy against brain tumors. | 002 | 3 | NIH | 8/4/2025 | $211,464 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA292487 | Targeting Leukemia Stem Cells with Small Molecule Heat Shock Transcription Factor 1 Degrader | 000 | 1 | NIH | 2/24/2025 | $502,516 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL126900 | Restoration and Function of S-Nitrosothiol in Stored Blood | 001 | 8 | NIH | 7/16/2025 | $56,724 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL126900 | Restoration and Function of S-Nitrosothiol in Stored Blood | 000 | 8 | NIH | 3/7/2025 | $510,505 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AI072219 | Understanding B-Lactam Resistance in Acinetobacter baumannii | 002 | 16 | NIH | 8/19/2025 | $520,792 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK124590 | Role of chive-derived exosome-like nanoparticles in suppressing inflammation in obesity | 001 | 5 | NIH | 6/12/2025 | $35,941 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AI072219 | Understanding B-Lactam Resistance in Acinetobacter baumannii | 001 | 15 | NIH | 2/21/2025 | $520,792 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK124590 | Role of chive-derived exosome-like nanoparticles in suppressing inflammation in obesity | 000 | 5 | NIH | 2/20/2025 | $323,470 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA299332 | Creating a transient metabolic catastrophe for AML therapy | 000 | 1 | NIH | 3/11/2025 | $491,357 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | D43TW012260 | Strengthening Research Capacity in Innovative Global Health Technologies for Non-Communicable Diseases in Uganda | 000 | 4 | NIH | 3/10/2025 | $246,419 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL126747 | Optical Tools to Assess the Role of Cardiac Function in the Development of Congenital Heart Defects | 001 | 10 | NIH | 8/4/2025 | $75,890 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL126747 | Optical Tools to Assess the Role of Cardiac Function in the Development of Congenital Heart Defects | 000 | 10 | NIH | 2/14/2025 | $683,011 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F30CA294611 | MR Fingerprinting for Characterization and Prediction of Glioblastoma Infiltration | 001 | 1 | NIH | 7/10/2025 | $0 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | T32TR004521 | Clinical and Translational Science Collaborative of Northern Ohio, CTSA Predoctoral T32 at Case Western Reserve University | 000 | 1 | NIH | 7/8/2025 | $456,728 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AI189290 | Bioinspired Point of Care Testing for HIV/HBV Co-infection | 000 | 1 | NIH | 7/7/2025 | $354,570 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R33NS133212 | Human-iPSC derived neuromuscular junctions as a model for neuromuscular diseases. | 000 | 2 | NIH | 8/15/2025 | $390,007 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R00AI173544 | Improving phage-based medicine with immunoengineering | 000 | 3 | NIH | 8/20/2025 | $248,998 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K12TR005469 | Clinical and Translational Science Collaborative of Northern Ohio, CTSA K12 Program at Case Western Reserve University | 000 | 1 | NIH | 8/13/2025 | $1,078,928 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R00NS135194 | Targeted Neuroplasticity via vagus nerve stimulation to improve urinary dysfunction after spinal cord injury | 000 | 2 | NIH | 8/14/2025 | $249,000 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30HL178232 | Cardiovascular risk prediction from small, low-densitycalcifications detected on CT calciumscore exams | 000 | 1 | NIH | 8/30/2025 | $54,538 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30AG097357 | Investigating glial priming by an early-life sensory experience | 001 | 1 | NIH | 9/2/2025 | $0 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30AG097357 | Investigating glial priming by an early-life sensory experience | 000 | 1 | NIH | 9/2/2025 | $54,538 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R03AG102041 | Prioritizing Alzheimer Disease Gene-Environment Studies Using MoTrPAC Cross-Species Tissue-Specific Exercise Response Transcriptomics | 000 | 1 | NIH | 9/22/2025 | $78,500 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | UG1EY037206 | Diabetes Endothelial Keratoplasty Study (DEKS): Impact of Diabetes and Other Predictors on Corneal Transplant Endothelial Cell Loss and Success | 000 | 1 | NIH | 8/18/2025 | $524,992 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG093797 | Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER): Testing the Efficacy of an Intervention to Prevent Psychological Elder Abuse in Family Caregiving | 000 | 1 | NIH | 9/10/2025 | $688,414 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31MH142011 | Social Determinants of Health, Family Functioning, and the Family Check-Up: Neighborhood and Educational Influences on Parenting, Youth Mental Health,and Response to Intervention. | 000 | 1 | NIH | 9/8/2025 | $49,538 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F31NS139574 | Evaluating the protein homeostasis of N-methyl-D-aspartate receptors containing pathogenic GluN2B subunits | 001 | 1 | NIH | 6/30/2025 | $0 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31NS139574 | Evaluating the protein homeostasis of N-methyl-D-aspartate receptors containing pathogenic GluN2B subunits | 002 | 1 | NIH | 9/15/2025 | $0 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F31NS139574 | Evaluating the protein homeostasis of N-methyl-D-aspartate receptors containing pathogenic GluN2B subunits | 000 | 1 | NIH | 6/30/2025 | $42,780 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AR078343 | Local immunometabolism modulating biomaterials for immunosuppressive applications | 001 | 5 | NIH | 5/19/2025 | $23,634 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AR078343 | Local immunometabolism modulating biomaterials for immunosuppressive applications | 000 | 5 | NIH | 3/17/2025 | $303,855 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K99HL179260 | Atomic-level Structural-omics of Platelet Membrane Proteins via Multi-scale Structural Biology Approaches | 000 | 1 | NIH | 7/15/2025 | $121,003 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R25CA225461 | Cancer-focused Summer Undergraduate Research (CanSUR) Program | 001 | 8 | NIH | 8/20/2025 | $431,508 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | T32NS077888 | Training in Neurodegenerative Diseases | 003 | 12 | NIH | 8/5/2025 | $239,629 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21NS144683 | Microglial-Mediated Glycosaminoglycan Catabolism in MPS VII Neuropathology. | 000 | 1 | NIH | 7/31/2025 | $453,033 |
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