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 | Issue Date FY: 2025 ( Subtotal = $58,349,302 ) (Continued on the next page) |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG076051 | Mechanism of white matter pathology in Alzheimer's disease | 000 | 4 | NIH | 11/28/2024 | $546,748 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01MD019185 | Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young, minority persons living with HIV | 000 | 2 | NIH | 11/28/2024 | $1,019,943 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HD110367 | The role of the female and male reproductive microenvironment in fertility fitness | 000 | 3 | NIH | 4/18/2025 | $598,274 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL156987 | Impact of microfibril turnover on vascular development and disease | 000 | 4 | NIH | 11/6/2024 | $362,250 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL166241 | Engineered polymeric adjuvants for heart-redirected targeting and gene therapy | 000 | 2 | NIH | 5/14/2025 | $594,531 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01EB034660 | Fluorescence image guided surgery, adjuvant PDT, and the immune response | 000 | 2 | NIH | 4/14/2025 | $577,657 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01NS120689 | Retooling innate immunity: An investigation of TLR-mediated glial priming across lifespan | 000 | 5 | NIH | 12/11/2024 | $362,250 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA280981 | Novel radiomic signatures for treatment response to neoadjuvant therapy in rectal cancers | 000 | 2 | NIH | 4/10/2025 | $548,446 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01MH130367 | Long-range GABAergic inhibition coordinates hippocampal-subcortical circuit activity in memory formation | 000 | 3 | NIH | 2/19/2025 | $412,267 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DE032670 | Substrate-mediated collective cell migration incalvarial bone expansion and disease. | 000 | 2 | NIH | 5/1/2025 | $651,333 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 001 | 3 | NIH | 11/8/2024 | $19,457 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 000 | 3 | NIH | 10/25/2024 | $629,110 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21CA280151 | Exploring SGLTs as Theranostic Targets for Cancer Metastasis | 000 | 2 | NIH | 11/13/2024 | $178,530 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269354 | Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and Acidosis | 000 | 3 | NIH | 10/31/2024 | $588,205 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DC020368 | Circuit mechanism of pheromone processing and innate behavior | 003 | 3 | NIH | 5/5/2025 | $109,348 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DC020368 | Circuit mechanism of pheromone processing and innate behavior | 001 | 3 | NIH | 1/23/2025 | $476,256 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269816 | Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | 000 | 3 | NIH | 11/6/2024 | $601,330 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21AI180421 | Role of ExoU island accessory genes in P. aeruginosa virulence | 000 | 2 | NIH | 5/13/2025 | $201,250 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R35GM154771 | Mapping RNA Binding Protein Interactions Within Cellular Microenvironments | 000 | 2 | NIH | 5/2/2025 | $402,500 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA272621 | Role of YB1 in health disparities in triple negative breast cancer | 000 | 3 | NIH | 4/21/2025 | $419,739 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K23HL169022 | Understanding the association of sleep on monocyte action in HIV infection | 001 | 2 | NIH | 1/23/2025 | $189,368 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K23HL169022 | Understanding the association of sleep on monocyte action in HIV infection | 003 | 2 | NIH | 4/15/2025 | $108,629 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F31AT012592 | Developing Real-world Understanding of Medical Music therapy using the Electronic Health Record (DRUMMER) | 000 | 2 | NIH | 12/9/2024 | $48,974 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | UH3DE030856 | Multi-Level Interventions to Reduce Oral Health Disparities among Adults in Primary Care Settings | 001 | 4 | NIH | 5/2/2025 | $1,192,061 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | UH3DE030856 | Multi-Level Interventions to Reduce Oral Health Disparities among Adults in Primary Care Settings | 001 | 4 | NIH | 5/2/2025 | $80,000 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL175410 | Assessment of the Impact of antihypertensive Medications on vascular and renal outcomes in Chronic Kidney Disease (AIM-CKD) | 000 | 2 | NIH | 4/25/2025 | $576,914 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01NS128226 | Structural diversity of cervid prions and phenotypic variation of chronic wasting disease | 000 | 3 | NIH | 4/9/2025 | $402,500 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG086365 | Protective Role of Mitochondrial CHCHD10 in Alzheimer's Disease through MAM and Mitophagy Mechanisms. | 000 | 2 | NIH | 4/7/2025 | $567,536 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HD109299 | tDCS During Contralaterally Controlled FES for Upper Extremity Hemiplegia | 000 | 3 | NIH | 4/11/2025 | $690,693 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01NS129876 | Investigation of brain-originating circRNAs as targets in blood-based stroke triage diagnostics | 000 | 3 | NIH | 4/15/2025 | $596,115 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K08DK135933 | A comprehensive approach to understanding the genetic causes of urinary stone disease: combining monogenic and polygenic analyses | 000 | 2 | NIH | 12/13/2024 | $161,535 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL165218 | Cardiovascular risk from comprehensive evaluation of the CT calcium score exam | 000 | 3 | NIH | 3/28/2025 | $690,422 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R33AT010806 | Enhancing Exercise and Psychotherapy to Treat Comorbid Addiction and Pain for ImprovingAdherence to Medication Assisted Treatment in Opioid Use Disorders | 000 | 4 | NIH | 1/2/2025 | $870,587 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01GM143256 | "Developing A Comprehensive Toolkit for Chemical Inducible Epigenome Remodeling" | 000 | 4 | NIH | 4/28/2025 | $322,000 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL172894 | S-Nitrosoglutathione therapy for oxidant disease of the neonatal airways and lung | 000 | 2 | NIH | 1/27/2025 | $533,073 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA252224 | Targeting Oncostatin M-Receptor to Suppress Metastasis and Therapy Failure | 000 | 5 | NIH | 1/27/2025 | $371,530 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F31CA291057 | Pathologically Interpretable Computational Imaging Predictor for Response to Total Neoadjuvant Treatment in Rectal Cancers | 000 | 1 | NIH | 5/1/2025 | $48,974 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21AG094047 | Synthetic replicas of TDP-43 filaments associated with frontotemporal dementia | 000 | 1 | NIH | 5/7/2025 | $442,750 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | UG1CA233234 | Case Comprehensive Cancer Center NCTN Lead Academic Participating Site | 000 | 6 | NIH | 3/6/2025 | $892,012 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DA060489 | The impact of poly-substance use on the crosstalk between microglia, astrocytes, and neurons that regulates HIV latency | 001 | 2 | NIH | 3/3/2025 | $637,775 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DA060489 | The impact of poly-substance use on the crosstalk between microglia, astrocytes, and neurons that regulates HIV latency | 002 | 2 | NIH | 4/10/2025 | $70,863 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL167159 | 5 D impulse mapping in the embryonic heart | 000 | 3 | NIH | 2/27/2025 | $613,429 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA287672 | Optimizing anti-wild-type IDH1 therapy in pancreatic cancer | 000 | 2 | NIH | 3/14/2025 | $594,955 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HD104601 | Sleep disparities' role in adolescent fatigue and functioning: A mixed-methods study | 001 | 4 | NIH | 4/22/2025 | $59,785 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HD104601 | Sleep disparities' role in adolescent fatigue and functioning: A mixed-methods study | 000 | 4 | NIH | 3/18/2025 | $538,064 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA266050 | The Microbiome and Mucosal Immunity in Cervical Cancer Disparities | 000 | 4 | NIH | 3/20/2025 | $547,754 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21CA288449 | Roles of gut-breast axis in breast pathophysiology | 000 | 2 | NIH | 3/3/2025 | $169,353 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK128143 | Estrogen-mediated immune regulation in human and experimental inflammatory bowel disease | 000 | 5 | NIH | 3/5/2025 | $355,097 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL156928 | Altered Circadian Rhythm Regulation in Cystic Fibrosis | 000 | 4 | NIH | 3/20/2025 | $563,589 |
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