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| Issue Date FY: 2024 ( Subtotal = $148,261,469 ) (Continued on the next page) |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA260847 | PSMA-targeted AuNPs for MR guided radiotherapy and radiosensitization | 001 | 4 | NIH | 4/17/2024 | $33,237 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA260847 | PSMA-targeted AuNPs for MR guided radiotherapy and radiosensitization | 000 | 4 | NIH | 1/22/2024 | $598,276 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL157405 | Tyrosine Kinases and Thrombosis | 001 | 3 | NIH | 6/20/2024 | $35,583 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL157405 | Tyrosine Kinases and Thrombosis | 000 | 3 | NIH | 1/19/2024 | $400,304 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL160857 | Mechanisms of oxygen off-loading from red blood cells in murine models of human disease | 001 | 3 | NIH | 6/21/2024 | $52,555 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL160857 | Mechanisms of oxygen off-loading from red blood cells in murine models of human disease | 000 | 3 | NIH | 1/17/2024 | $591,248 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | K01DK127008 | Effect of an Anti-Inflammatory Diet on Gut Homeostasis in Active and Experimental Crohn's Disease | 000 | 4 | NIH | 12/12/2023 | $121,770 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AI173549 | Structural studies of gasdermin E and its recognition by caspase-3. | 001 | 2 | NIH | 5/10/2024 | $8,050 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AI173549 | Structural studies of gasdermin E and its recognition by caspase-3. | 000 | 2 | NIH | 10/25/2023 | $72,450 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL156987 | Impact of microfibril turnover on vascular development and disease | 003 | 3 | NIH | 6/14/2024 | $32,201 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL156987 | Impact of microfibril turnover on vascular development and disease | 002 | 3 | NIH | 11/14/2023 | $362,250 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG080287 | Reduced allelic dosage of CLP1 attenuates cognitive dysfunction and pathological burden in transgenic mouse models of Alzheimer’s disease | 001 | 2 | NIH | 5/1/2024 | $15,520 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG077132 | Evaluation of genetic and metabolic markers in the development of urinary urgency incontinence | 001 | 2 | NIH | 5/1/2024 | $8,288 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG080287 | Reduced allelic dosage of CLP1 attenuates cognitive dysfunction and pathological burden in transgenic mouse models of Alzheimer’s disease | 000 | 2 | NIH | 11/6/2023 | $139,685 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG077132 | Evaluation of genetic and metabolic markers in the development of urinary urgency incontinence | 000 | 2 | NIH | 11/16/2023 | $74,596 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH130367 | Long-range GABAergic inhibition coordinates hippocampal-subcortical circuit activity in memory formation | 000 | 2 | NIH | 1/19/2024 | $436,518 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21AI169561 | Functional genomic characterization of diverse bat innate immune mechanisms | 001 | 2 | NIH | 5/13/2024 | $20,125 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21AI169561 | Functional genomic characterization of diverse bat innate immune mechanisms | 000 | 2 | NIH | 10/24/2023 | $181,125 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 001 | 2 | NIH | 5/13/2024 | $64,857 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 000 | 2 | NIH | 11/1/2023 | $583,710 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30CA294663 | Epigenetic drivers of lung metastasis in osteosarcoma | 000 | 1 | NIH | 6/17/2024 | $53,974 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01DE032670 | Substrate-mediated collective cell migration incalvarial bone expansion and disease. | 000 | 1 | NIH | 7/11/2024 | $682,663 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH117643 | Brain serotonin neuron gene regulatory networks and chromatin architecture | 001 | 5 | NIH | 5/15/2024 | $44,011 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01MH117643 | Brain serotonin neuron gene regulatory networks and chromatin architecture | 000 | 5 | NIH | 10/17/2023 | $396,097 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01DK119506 | Novel Regulation of Renal Function by S-Nitrosylation | 000 | 6 | NIH | 12/7/2023 | $540,667 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AG065240 | Role of brain lipid metabolism in Alzheimer's disease | 001 | 5 | NIH | 6/4/2024 | $60,383 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01AG065240 | Role of brain lipid metabolism in Alzheimer's disease | 000 | 5 | NIH | 1/22/2024 | $543,441 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL128053 | The role of the proximal nephron in salt-sensitive hypertension | 001 | 8 | NIH | 6/24/2024 | $50,742 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL128053 | The role of the proximal nephron in salt-sensitive hypertension | 000 | 8 | NIH | 11/30/2023 | $570,836 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30EY031566 | Identification of novel phosphodiesterase (PDE)-modulating compounds and characterization of associated cytoprotective pathways in lightdamagedretina | 001 | 4 | NIH | 6/7/2024 | $1,280 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30EY031566 | Identification of novel phosphodiesterase (PDE)-modulating compounds and characterization of associated cytoprotective pathways in lightdamagedretina | 000 | 4 | NIH | 12/4/2023 | $52,694 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG080175 | Bacterial triggers of neural inflammation. | 001 | 2 | NIH | 5/1/2024 | $16,100 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R03AG080175 | Bacterial triggers of neural inflammation. | 000 | 2 | NIH | 11/16/2023 | $144,900 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HG012384 | Mapping heritable chromatin loop variants with allele-specific Hi-C analysis | 001 | 2 | NIH | 6/14/2024 | $50,882 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R21NS139431 | Developing single nuclei tRNA-seq to profile tRNA diversity at the single cell level | 000 | 1 | NIH | 7/8/2024 | $442,750 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HG012384 | Mapping heritable chromatin loop variants with allele-specific Hi-C analysis | 000 | 2 | NIH | 1/17/2024 | $572,425 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01GM154832 | Molecular interactions and regulatory events in telomere maintenance | 000 | 1 | NIH | 7/5/2024 | $422,899 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30CA250254 | Role of SerpinB3 in glioblastoma cancer stem cells | 001 | 5 | NIH | 5/7/2024 | $1,280 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30CA250254 | Role of SerpinB3 in glioblastoma cancer stem cells | 000 | 5 | NIH | 12/20/2023 | $52,694 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01CA291963 | Mechanisms of Androgen Receptor Inverse Agonists in Advanced Prostate Cancer | 000 | 1 | NIH | 7/5/2024 | $606,869 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30CA294741 | Translation Regulation Contributes to Hypoxia Adaptation in Glioblastoma | 000 | 1 | NIH | 7/9/2024 | $53,974 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R35GM154859 | Mechanistic Insights into Single-Strand Break Repair Within Chromatin | 000 | 1 | NIH | 7/4/2024 | $402,500 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL121212 | Heteromutivalent Peptide-Lipid Nanoconstructs as Artificial Platelet Analogues | 001 | 9 | NIH | 6/20/2024 | $42,620 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | F30CA294669 | Defining features of the neoantigen-specific T cell response against a common EGFR mutation in lung cancer | 000 | 1 | NIH | 6/14/2024 | $53,974 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R01HL121212 | Heteromutivalent Peptide-Lipid Nanoconstructs as Artificial Platelet Analogues | 000 | 9 | NIH | 3/4/2024 | $479,471 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R35GM154771 | Mapping RNA Binding Protein Interactions Within Cellular Microenvironments | 000 | 1 | NIH | 6/26/2024 | $402,500 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | AY2AX000011 | OMEGA: Orchestrating Multifaceted Engineering for Growing Artificial Joints | 000 | 1 | NIH | 3/26/2024 | $20,404,251 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | R56AI186612 | Gaining a clear view of HIV cell-cell spread using APEX proximity labeling | 000 | 1 | NIH | 7/22/2024 | $515,282 |
| 2024 | 2024 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-1712 | CUYAHOGA | USA | D4033337 | Graduate Psychology Education Programs | 00 | 6 | HRSA | 6/5/2024 | $37,453 |
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