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 | Issue Date FY: 2025 ( Subtotal = $82,568,081 ) (Continued on the next page) |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01MD019185 | Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young, minority persons living with HIV | 000 | 2 | NIH | 11/28/2024 | $1,019,943 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | T32GM152319 | Medical Scientist Training Program at Case Western Reserve University | 000 | 2 | NIH | 5/30/2025 | $1,632,261 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01EB034660 | Fluorescence image guided surgery, adjuvant PDT, and the immune response | 000 | 2 | NIH | 4/14/2025 | $577,657 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01MH130367 | Long-range GABAergic inhibition coordinates hippocampal-subcortical circuit activity in memory formation | 000 | 3 | NIH | 2/19/2025 | $412,267 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DE032670 | Substrate-mediated collective cell migration incalvarial bone expansion and disease. | 000 | 2 | NIH | 5/1/2025 | $651,333 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA280981 | Novel radiomic signatures for treatment response to neoadjuvant therapy in rectal cancers | 001 | 2 | NIH | 5/23/2025 | $60,938 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA280981 | Novel radiomic signatures for treatment response to neoadjuvant therapy in rectal cancers | 000 | 2 | NIH | 4/10/2025 | $548,446 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA276712 | Improving Understanding of Quality End of Life Care Using a Dyadic Approach | 000 | 3 | NIH | 6/11/2025 | $649,213 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01NS120689 | Retooling innate immunity: An investigation of TLR-mediated glial priming across lifespan | 000 | 5 | NIH | 12/11/2024 | $362,250 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R35GM154859 | Mechanistic Insights into Single-Strand Break Repair Within Chromatin | 000 | 2 | NIH | 6/6/2025 | $402,500 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F30CA294669 | Defining features of the neoantigen-specific T cell response against a common EGFR mutation in lung cancer | 000 | 2 | NIH | 6/12/2025 | $54,538 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 001 | 3 | NIH | 11/8/2024 | $19,457 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 000 | 3 | NIH | 10/25/2024 | $629,110 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269816 | Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | 001 | 3 | NIH | 6/25/2025 | $66,814 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269816 | Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | 000 | 3 | NIH | 11/6/2024 | $601,330 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DC020368 | Circuit mechanism of pheromone processing and innate behavior | 003 | 3 | NIH | 5/5/2025 | $109,348 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DC020368 | Circuit mechanism of pheromone processing and innate behavior | 001 | 3 | NIH | 1/23/2025 | $476,256 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG081622 | Somatic mutation rates in healthy aging | 000 | 3 | NIH | 5/14/2025 | $623,672 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21CA280151 | Exploring SGLTs as Theranostic Targets for Cancer Metastasis | 001 | 2 | NIH | 6/18/2025 | $19,836 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21CA280151 | Exploring SGLTs as Theranostic Targets for Cancer Metastasis | 000 | 2 | NIH | 11/13/2024 | $178,530 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269354 | Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and Acidosis | 001 | 3 | NIH | 5/29/2025 | $65,355 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269354 | Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and Acidosis | 000 | 3 | NIH | 10/31/2024 | $588,205 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK128143 | Estrogen-mediated immune regulation in human and experimental inflammatory bowel disease | 002 | 5 | NIH | 6/11/2025 | $39,454 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK128143 | Estrogen-mediated immune regulation in human and experimental inflammatory bowel disease | 000 | 5 | NIH | 3/5/2025 | $355,097 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA266050 | The Microbiome and Mucosal Immunity in Cervical Cancer Disparities | 001 | 4 | NIH | 6/4/2025 | $60,859 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA266050 | The Microbiome and Mucosal Immunity in Cervical Cancer Disparities | 000 | 4 | NIH | 3/20/2025 | $547,754 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK128463 | Role of Sam68 in Proinflammatory Signaling | 001 | 4 | NIH | 6/26/2025 | $56,227 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK128463 | Role of Sam68 in Proinflammatory Signaling | 000 | 4 | NIH | 2/20/2025 | $506,054 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AR078343 | Local immunometabolism modulating biomaterials for immunosuppressive applications | 001 | 5 | NIH | 5/19/2025 | $23,634 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AR078343 | Local immunometabolism modulating biomaterials for immunosuppressive applications | 000 | 5 | NIH | 3/17/2025 | $303,855 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K01DK125526 | The Intestinal Mycobiome and IBD | 000 | 5 | NIH | 2/27/2025 | $121,770 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21ES036031 | Healthy Futures Research Study: Linking somatic mutation rate with baseline exposure in East Palestine | 000 | 2 | NIH | 3/11/2025 | $547,386 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL157405 | Tyrosine Kinases and Thrombosis | 000 | 4 | NIH | 2/28/2025 | $366,636 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | D43TW012260 | Strengthening Research Capacity in Innovative Global Health Technologies for Non-Communicable Diseases in Uganda | 000 | 4 | NIH | 3/10/2025 | $246,419 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG085316 | Identifying T cell determinants of heritable Frontotemporal dementia | 001 | 2 | NIH | 6/10/2025 | $51,573 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG085316 | Identifying T cell determinants of heritable Frontotemporal dementia | 000 | 2 | NIH | 3/20/2025 | $580,183 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL126747 | Optical Tools to Assess the Role of Cardiac Function in the Development of Congenital Heart Defects | 000 | 10 | NIH | 2/14/2025 | $683,011 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA299332 | Creating a transient metabolic catastrophe for AML therapy | 000 | 1 | NIH | 3/11/2025 | $491,357 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA235152 | Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy | 003 | 7 | NIH | 5/28/2025 | $40,510 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA235152 | Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy | 000 | 7 | NIH | 2/12/2025 | $364,605 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL126900 | Restoration and Function of S-Nitrosothiol in Stored Blood | 000 | 8 | NIH | 3/7/2025 | $510,505 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R00EY034168 | Nanoparticle-Based Tracking of Retinal Ganglion Cell Transplant | 001 | 3 | NIH | 6/11/2025 | $171 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R00EY034168 | Nanoparticle-Based Tracking of Retinal Ganglion Cell Transplant | 000 | 3 | NIH | 2/25/2025 | $249,000 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F30HD114399 | Investigating the Structural Basis of Human Glycine Receptor Modulation for Neurodevelopmental Disorders | 001 | 2 | NIH | 6/2/2025 | $564 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F30HD114399 | Investigating the Structural Basis of Human Glycine Receptor Modulation for Neurodevelopmental Disorders | 000 | 2 | NIH | 3/7/2025 | $53,974 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA292487 | Targeting Leukemia Stem Cells with Small Molecule Heat Shock Transcription Factor 1 Degrader | 000 | 1 | NIH | 2/24/2025 | $502,516 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK124590 | Role of chive-derived exosome-like nanoparticles in suppressing inflammation in obesity | 001 | 5 | NIH | 6/12/2025 | $35,941 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK124590 | Role of chive-derived exosome-like nanoparticles in suppressing inflammation in obesity | 000 | 5 | NIH | 2/20/2025 | $323,470 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | UG1CA233234 | Case Comprehensive Cancer Center NCTN Lead Academic Participating Site | 000 | 6 | NIH | 3/6/2025 | $892,012 |
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