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 | Issue Date FY: 2026 ( Subtotal = $29,405,558 ) (Continued on the next page) |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA306944 | Theranostic Approaches to Breast Cancer Using Image Guided Surgery and Adjuvant PTT | 000 | 1 | NIH | 3/13/2026 | $630,108 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DA060489 | The impact of poly-substance use on the crosstalk between microglia, astrocytes, and neurons that regulates HIV latency | 000 | 3 | NIH | 2/26/2026 | $708,638 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DC016696 | Mechanisms of Developmental Plasticity in the Mammalian Olfactory System | 000 | 7 | NIH | 2/11/2026 | $611,674 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DC021795 | Calcium Regulation in Cochlear Cells | 001 | 2 | NIH | 2/11/2026 | $63,916 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DC020368 | Circuit mechanism of pheromone processing and innate behavior | 001 | 4 | NIH | 2/10/2026 | $47,626 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DC020368 | Circuit mechanism of pheromone processing and innate behavior | 000 | 4 | NIH | 12/5/2025 | $428,630 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01DC021795 | Calcium Regulation in Cochlear Cells | 000 | 2 | NIH | 1/10/2026 | $575,254 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA275910 | MIZ1 Activation in Triple-negative Breast Cancer Racial Disparities | 000 | 3 | NIH | 2/2/2026 | $555,952 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA269354 | Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and Acidosis | 000 | 4 | NIH | 12/11/2025 | $587,133 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA269816 | Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | 000 | 4 | NIH | 12/9/2025 | $601,330 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA295877 | A Clinical Trial of Cancer Prevention by Biomarker Based Detections of Barrett's Esophagus and Its Progression | 000 | 2 | NIH | 2/24/2026 | $1,400,846 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA288626 | Cyclin D1 as a driver of HNSCC | 000 | 2 | NIH | 12/12/2025 | $418,864 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA296150 | Leveraging Community-Based Food Pantry Settings for Provision of Tobacco Cessation Treatment | 000 | 2 | NIH | 1/30/2026 | $601,066 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AI191807 | The role of the precursor HIV-1 protease in drug resistance. | 000 | 2 | NIH | 12/29/2025 | $507,792 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA196643 | Mechanisms of metabolic reprogramming by PIK3CA oncogenic mutations | 000 | 8 | NIH | 1/23/2026 | $362,250 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA235152 | Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy | 000 | 8 | NIH | 1/15/2026 | $364,605 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AI171104 | Selective Inhibitors of T Cell Activation Target Exportin-1 at Cys528 to Suppress Pathological T Cell Activation | 000 | 4 | NIH | 1/12/2026 | $508,611 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 000 | 4 | NIH | 11/25/2025 | $648,567 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG076051 | Mechanism of white matter pathology in Alzheimer's disease | 001 | 5 | NIH | 2/23/2026 | $60,750 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG076051 | Mechanism of white matter pathology in Alzheimer's disease | 000 | 5 | NIH | 12/26/2025 | $546,748 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG080924 | SSH1-Nrf2 nexus in tipping the balance between degeneration and protection in tauopathies. | 001 | 4 | NIH | 2/24/2026 | $51,214 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG080924 | SSH1-Nrf2 nexus in tipping the balance between degeneration and protection in tauopathies. | 000 | 4 | NIH | 12/5/2025 | $460,922 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG085316 | Identifying T cell determinants of heritable Frontotemporal dementia | 000 | 3 | NIH | 3/26/2026 | $584,649 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG096172 | Alzheimer Disease Genetic Analysis to Identify Potential Therapeutic Targets (ADAPTT) | 000 | 1 | NIH | 2/4/2026 | $1,256,627 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG096873 | Modifiers of Tau Seeds in Human Brain | 000 | 1 | NIH | 3/5/2026 | $691,999 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R00GM143550 | Integration of metabolism and chromatin in regulating gene expression in vivo | 000 | 5 | NIH | 3/4/2026 | $249,000 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K23HL169022 | Understanding the association of sleep on monocyte action in HIV infection | 000 | 3 | NIH | 2/11/2026 | $189,377 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K01DK128304 | Using transcriptomics and ex vivo organotypic models to discover mechanisms of APOL1-associated podocytopathies | 000 | 4 | NIH | 12/10/2025 | $130,741 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AG095389 | CHCHD10 in Tauopathy in AD and ADRD | 000 | 1 | NIH | 12/29/2025 | $431,750 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI192237 | CMV reactivation in the vasculature of people with HIV drives T cell responses | 000 | 1 | NIH | 2/20/2026 | $233,790 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R03DE035522 | An Atlas of Bacterial Physiology in the Human Oral Cavity | 000 | 1 | NIH | 2/4/2026 | $340,149 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS114510 | Genetic Control of Respiratory Motor Circuit Development, Connectivity and Maintenance | 000 | 7 | NIH | 2/24/2026 | $467,814 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01NS129876 | Investigation of brain-originating circRNAs as targets in blood-based stroke triage diagnostics | 000 | 4 | NIH | 3/19/2026 | $627,857 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MH129294 | The role of subcortical inputs to the hippocampal CA3 region in fear memory | 000 | 4 | NIH | 12/15/2025 | $394,752 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MH130476 | The role of heparan sulfate modification on neurexin1 in synapse development | 000 | 3 | NIH | 12/19/2025 | $418,262 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MH130367 | Long-range GABAergic inhibition coordinates hippocampal-subcortical circuit activity in memory formation | 000 | 4 | NIH | 1/20/2026 | $485,020 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL167159 | 5 D impulse mapping in the embryonic heart | 000 | 4 | NIH | 3/20/2026 | $641,471 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL176819 | Leveraging HSF1 Attenuation to Transform Clonal Hematopoiesis into Beneficial Hematopoiesis | 001 | 2 | NIH | 3/24/2026 | $21,595 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL176819 | Leveraging HSF1 Attenuation to Transform Clonal Hematopoiesis into Beneficial Hematopoiesis | 000 | 2 | NIH | 2/6/2026 | $683,843 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL172894 | S-Nitrosoglutathione therapy for oxidant disease of the neonatal airways and lung | 001 | 3 | NIH | 3/25/2026 | $16,469 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL172894 | S-Nitrosoglutathione therapy for oxidant disease of the neonatal airways and lung | 000 | 3 | NIH | 3/6/2026 | $521,532 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MD019185 | Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young people with HIV | 001 | 3 | NIH | 2/21/2026 | $112,811 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01MD019185 | Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young people with HIV | 000 | 3 | NIH | 12/7/2025 | $1,015,306 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HG012384 | Mapping heritable chromatin loop variants with allele-specific Hi-C analysis | 000 | 4 | NIH | 2/10/2026 | $652,596 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL156987 | Impact of microfibril turnover on vascular development and disease | 000 | 5 | NIH | 1/30/2026 | $382,376 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL126900 | Restoration and Function of S-Nitrosothiol in Stored Blood | 000 | 9 | NIH | 2/19/2026 | $538,868 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL126900 | Restoration and Function of S-Nitrosothiol in Stored Blood | 001 | 9 | NIH | 3/24/2026 | $17,016 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01GM125844 | Defining Molecular Interactions that Drive Mitochondrial Fission | 001 | 8 | NIH | 3/12/2026 | $31,804 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01GM125844 | Defining Molecular Interactions that Drive Mitochondrial Fission | 000 | 8 | NIH | 2/5/2026 | $286,243 |
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