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 | Issue Date FY: 2025 ( Subtotal = $88,018,315 ) (Continued on the next page) |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F30CA294669 | Defining features of the neoantigen-specific T cell response against a common EGFR mutation in lung cancer | 000 | 2 | NIH | 6/12/2025 | $54,538 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 001 | 3 | NIH | 11/8/2024 | $19,457 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AI172944 | Development and evaluation of a second-generation fungerp for systemic and cutaneous C. auris infection | 000 | 3 | NIH | 10/25/2024 | $629,110 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DC020368 | Circuit mechanism of pheromone processing and innate behavior | 003 | 3 | NIH | 5/5/2025 | $109,348 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DC020368 | Circuit mechanism of pheromone processing and innate behavior | 001 | 3 | NIH | 1/23/2025 | $476,256 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269816 | Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | 001 | 3 | NIH | 6/25/2025 | $66,814 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269816 | Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmu | 000 | 3 | NIH | 11/6/2024 | $601,330 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG081622 | Somatic mutation rates in healthy aging | 000 | 3 | NIH | 5/14/2025 | $623,672 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269354 | Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and Acidosis | 001 | 3 | NIH | 5/29/2025 | $65,355 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA269354 | Magnetic Resonance Fingerprinting of Tumor Vascular Perfusion and Acidosis | 000 | 3 | NIH | 10/31/2024 | $588,205 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21CA280151 | Exploring SGLTs as Theranostic Targets for Cancer Metastasis | 001 | 2 | NIH | 6/18/2025 | $19,836 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21CA280151 | Exploring SGLTs as Theranostic Targets for Cancer Metastasis | 000 | 2 | NIH | 11/13/2024 | $178,530 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01LM014520 | Accelerating Genomic Data Sharing and Collaborative Research with Privacy Protection | 000 | 3 | NIH | 5/19/2025 | $286,000 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01LM014520 | Accelerating Genomic Data Sharing and Collaborative Research with Privacy Protection | 000 | 3 | NIH | 5/19/2025 | $346,251 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21CA288449 | Roles of gut-breast axis in breast pathophysiology | 001 | 2 | NIH | 5/22/2025 | $18,816 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21CA288449 | Roles of gut-breast axis in breast pathophysiology | 000 | 2 | NIH | 3/3/2025 | $169,353 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA266050 | The Microbiome and Mucosal Immunity in Cervical Cancer Disparities | 000 | 4 | NIH | 3/20/2025 | $547,754 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA266050 | The Microbiome and Mucosal Immunity in Cervical Cancer Disparities | 001 | 4 | NIH | 6/4/2025 | $60,859 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K01DK125526 | The Intestinal Mycobiome and IBD | 000 | 5 | NIH | 2/27/2025 | $121,770 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK128463 | Role of Sam68 in Proinflammatory Signaling | 001 | 4 | NIH | 6/26/2025 | $56,227 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK128463 | Role of Sam68 in Proinflammatory Signaling | 000 | 4 | NIH | 2/20/2025 | $506,054 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | D43TW012260 | Strengthening Research Capacity in Innovative Global Health Technologies for Non-Communicable Diseases in Uganda | 000 | 4 | NIH | 3/10/2025 | $246,419 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG085316 | Identifying T cell determinants of heritable Frontotemporal dementia | 001 | 2 | NIH | 6/10/2025 | $51,573 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG085316 | Identifying T cell determinants of heritable Frontotemporal dementia | 000 | 2 | NIH | 3/20/2025 | $580,183 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01NS122218 | Deubiquitinase USP19 in TDP-43 pathogenesis. | 000 | 2 | NIH | 7/3/2025 | $595,610 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R21ES036031 | Healthy Futures Research Study: Linking somatic mutation rate with baseline exposure in East Palestine | 000 | 2 | NIH | 3/11/2025 | $547,386 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL157405 | Tyrosine Kinases and Thrombosis | 000 | 4 | NIH | 2/28/2025 | $366,636 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K12CA299033 | Clinical Oncology Research Program (CORP) | 000 | 1 | NIH | 7/3/2025 | $50,000 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F30HD114399 | Investigating the Structural Basis of Human Glycine Receptor Modulation for Neurodevelopmental Disorders | 001 | 2 | NIH | 6/2/2025 | $564 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | F30HD114399 | Investigating the Structural Basis of Human Glycine Receptor Modulation for Neurodevelopmental Disorders | 000 | 2 | NIH | 3/7/2025 | $53,974 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R00EY034168 | Nanoparticle-Based Tracking of Retinal Ganglion Cell Transplant | 001 | 3 | NIH | 6/11/2025 | $171 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R00EY034168 | Nanoparticle-Based Tracking of Retinal Ganglion Cell Transplant | 000 | 3 | NIH | 2/25/2025 | $249,000 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA299332 | Creating a transient metabolic catastrophe for AML therapy | 000 | 1 | NIH | 3/11/2025 | $491,357 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL126747 | Optical Tools to Assess the Role of Cardiac Function in the Development of Congenital Heart Defects | 000 | 10 | NIH | 2/14/2025 | $683,011 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK124590 | Role of chive-derived exosome-like nanoparticles in suppressing inflammation in obesity | 001 | 5 | NIH | 6/12/2025 | $35,941 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01DK124590 | Role of chive-derived exosome-like nanoparticles in suppressing inflammation in obesity | 000 | 5 | NIH | 2/20/2025 | $323,470 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA235152 | Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy | 003 | 7 | NIH | 5/28/2025 | $40,510 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA235152 | Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy | 000 | 7 | NIH | 2/12/2025 | $364,605 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL126900 | Restoration and Function of S-Nitrosothiol in Stored Blood | 000 | 8 | NIH | 3/7/2025 | $510,505 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA292487 | Targeting Leukemia Stem Cells with Small Molecule Heat Shock Transcription Factor 1 Degrader | 000 | 1 | NIH | 2/24/2025 | $502,516 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA252224 | Targeting Oncostatin M-Receptor to Suppress Metastasis and Therapy Failure | 001 | 5 | NIH | 5/22/2025 | $41,280 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01CA252224 | Targeting Oncostatin M-Receptor to Suppress Metastasis and Therapy Failure | 000 | 5 | NIH | 1/27/2025 | $371,530 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL146676 | Computer modeling of myosin binding protein C and its effects on cardiac contraction | 000 | 6 | NIH | 3/5/2025 | $613,202 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | UG1CA233234 | Case Comprehensive Cancer Center NCTN Lead Academic Participating Site | 000 | 6 | NIH | 3/6/2025 | $892,012 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01HL172894 | S-Nitrosoglutathione therapy for oxidant disease of the neonatal airways and lung | 000 | 2 | NIH | 1/27/2025 | $533,073 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG086365 | Protective Role of Mitochondrial CHCHD10 in Alzheimer's Disease through MAM and Mitophagy Mechanisms. | 001 | 2 | NIH | 6/13/2025 | $50,448 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | R01AG086365 | Protective Role of Mitochondrial CHCHD10 in Alzheimer's Disease through MAM and Mitophagy Mechanisms. | 000 | 2 | NIH | 4/7/2025 | $567,536 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | K08DK135933 | A comprehensive approach to understanding the genetic causes of urinary stone disease: combining monogenic and polygenic analyses | 000 | 2 | NIH | 12/13/2024 | $161,535 |
| | 2025 | 2025 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106-4901 | CUYAHOGA | USA | UG1HD021364 | NICHD Neonatal Research Network Clinical Center - Case Western Reserve University | 000 | 40 | NIH | 4/3/2025 | $354,200 |
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