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 | Issue Date FY: 2026 ( Subtotal = $140,077,911 ) (Continued on the next page) |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG086365 | Protective Role of Mitochondrial CHCHD10 in Alzheimer's Disease through MAM and Mitophagy Mechanisms. | 000 | 3 | NIH | 6/5/2026 | $630,595 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG089561 | Role of EphA1/A2 domain-domain and -membrane interactions for receptor specificity and Blood Brain Barrier dysfunction | 000 | 3 | NIH | 7/9/2026 | $805,356 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R35GM150668 | Deciphering enhancer regulation in stem cells | 000 | 4 | NIH | 7/9/2026 | $402,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | UG1HD021364 | NICHD Neonatal Research Network Clinical Center - Case Western Reserve University | 000 | 41 | NIH | 5/12/2026 | $354,200 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R35GM150678 | Arginyl-tRNA beyond translation: mechanism and regulation of protein arginylation | 001 | 4 | NIH | 7/27/2026 | $125,155 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R35GM150678 | Arginyl-tRNA beyond translation: mechanism and regulation of protein arginylation | 000 | 4 | NIH | 7/14/2026 | $402,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HG013718 | Supporting Just-in-Time Consent for Prenatal Screening | 001 | 3 | NIH | 8/4/2026 | $770,433 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K01DK128304 | Using transcriptomics and ex vivo organotypic models to discover mechanisms of APOL1-associated podocytopathies | 000 | 4 | NIH | 12/10/2025 | $130,741 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | U01CA271867 | Validation of Biomarkers for predicting Barrett's esophagus that will or will not: i) progress towards cancer, or ii) recur after ablation | 000 | 5 | NIH | 8/11/2026 | $1,040,932 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01GM154832 | Molecular interactions and regulatory events in telomere maintenance | 000 | 3 | NIH | 4/21/2026 | $422,899 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL173989 | Biological Basis of Genetic cMyBP-C Cardiomyopathies | 000 | 3 | NIH | 5/14/2026 | $640,728 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R25NS135590 | Research Immersion in Brain, Spinal cord (RIBS), & Peripheral nerve disorders for High School Students | 000 | 3 | NIH | 5/7/2026 | $135,000 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA294741 | Translation Regulation Contributes to Hypoxia Adaptation in Glioblastoma | 000 | 3 | NIH | 7/10/2026 | $55,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | U24NS107270 | Case Western Reserve University StrokeNet University Regional Coordinating Center | 000 | 8 | NIH | 3/25/2026 | $429,468 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | DP2AI184733 | Defining the role of single-cell heterogeneity in bacterial vaginosis | 000 | 3 | NIH | 7/30/2026 | $478,433 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R00CA263194 | Novel regulation of the CDK4/Cdh1/Pin1 signaling axis for targeted breast cancer therapies | 000 | 5 | NIH | 7/20/2026 | $248,999 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG076051 | Mechanism of white matter pathology in Alzheimer's disease | 001 | 5 | NIH | 2/23/2026 | $60,750 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG076051 | Mechanism of white matter pathology in Alzheimer's disease | 000 | 5 | NIH | 12/26/2025 | $546,748 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG100745 | A Randomized Trial of REFRAME: an Emotion Regulation Intervention to Improve Psychological Outcomes in Surrogate Decision-Makers of the Critically Ill | 001 | 1 | NIH | 8/14/2026 | $125,534 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG100745 | A Randomized Trial of REFRAME: an Emotion Regulation Intervention to Improve Psychological Outcomes in Surrogate Decision-Makers of the Critically Ill | 000 | 1 | NIH | 5/27/2026 | $659,056 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31ES038016 | Examining Rural and Border Emergency Management Infrastructure: An East Palestine Case Study | 001 | 1 | NIH | 5/20/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31ES038016 | Examining Rural and Border Emergency Management Infrastructure: An East Palestine Case Study | 000 | 1 | NIH | 5/20/2026 | $49,418 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | RF1NS145403 | External Environmental Determinants of Alzheimers Type Dementias and Mechanisms | 000 | 1 | NIH | 7/14/2026 | $1,884,854 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA318437 | Ultrasound-triggered nanobubble gene therapy for prostate cancer radiosensitization | 001 | 1 | NIH | 7/23/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA318437 | Ultrasound-triggered nanobubble gene therapy for prostate cancer radiosensitization | 000 | 1 | NIH | 7/23/2026 | $55,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA310113 | Dynamic Contrast Enhanced- Magnetic Resonance Fingerprinting to Detect Early Response to Neoadjuvant Chemotherapy in Breast Cancer Patient | 001 | 1 | NIH | 7/31/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F30CA310113 | Dynamic Contrast Enhanced- Magnetic Resonance Fingerprinting to Detect Early Response to Neoadjuvant Chemotherapy in Breast Cancer Patient | 000 | 1 | NIH | 7/31/2026 | $55,114 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL184919 | Low-Field Magnetic Resonance Imaging Guided Robotic Catheter System for Ventricular Tachycardia Ablation | 000 | 1 | NIH | 6/10/2026 | $760,476 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01GM169393 | DMS/NIGMS 1:Structure-Enhanced Statistical and Machine Learning Methods for Spatial Transcriptomics Cell Type Deconvolution and its Applications | 000 | 1 | NIH | 7/22/2026 | $200,001 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AA032476 | Effects of perinatal ethanol exposure on immature respiratory control | 000 | 1 | NIH | 7/22/2026 | $550,442 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R25GM161964 | CWRU Postbaccalaureate Research Education Program | 000 | 1 | NIH | 6/10/2026 | $502,792 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21CA318125 | Photobiomodulation-Enhanced CAR-T Cell Therapy | 000 | 1 | NIH | 7/31/2026 | $393,812 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | RF1AG094791 | Neurovascular Coupling and Waste Clearance in Aging Brain | 000 | 1 | NIH | 7/31/2026 | $3,153,437 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K23AT014015 | Transcutaneous Electrical Acustimulation Synchronized with Natural Breathing for Treatment of Epigastric Pain Syndrome | 000 | 1 | NIH | 7/22/2026 | $189,000 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | U01CA304453 | Mechanisms of regulation of metastasis by cancer extracellular vesicle-activated pathway | 000 | 1 | NIH | 7/9/2026 | $667,575 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01EB037413 | Predicting Efficacy of Nanomedicine Based Chemotherapeutics using Contrast Enhanced Ultrasound | 000 | 1 | NIH | 4/27/2026 | $531,541 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI191916 | Investigating Plasma Cell-Free Hemoglobin as a Driver of Cardiovascular Disease Risk in HIV-Positive Individuals | 000 | 1 | NIH | 4/21/2026 | $235,500 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21HL187010 | Plasma Cell-Free Hemoglobin: A Potential Modulator of Immune Dysregulation in HIV | 000 | 1 | NIH | 8/13/2026 | $431,750 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01AG099323 | Uncovering the Therapeutic Potential of Semaglutide in Alzheimer's Disease: Insights from Animal Models and Real-World Clinical Data | 000 | 1 | NIH | 8/13/2026 | $655,673 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL184157 | Decision support for ischemia imaging based on AI analysis of low-cost/no-cost screening CT and ECG data | 000 | 1 | NIH | 7/16/2026 | $1,573,126 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21AI196274 | Leveraging Large Language Models for the Design of Monoclonal Antibodies Against Malaria | 000 | 1 | NIH | 4/7/2026 | $282,757 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31CA314408 | Defining fatty acid desaturase 2 (FADS2) as a novel therapeutic target in Ewing sarcoma | 001 | 1 | NIH | 5/19/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | F31CA314408 | Defining fatty acid desaturase 2 (FADS2) as a novel therapeutic target in Ewing sarcoma | 000 | 1 | NIH | 5/19/2026 | $42,696 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R21TW013237 | TRI-CARE: Triplex Cellphone Assay for Rapid Evaluation of HIV, HBV and HCV Viral Load | 000 | 1 | NIH | 8/13/2026 | $440,709 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01HL185525 | The "bait and switch" gene therapy for cardiomyopathies | 000 | 1 | NIH | 7/7/2026 | $1,532,398 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | T32AR085533 | Training Program in Musculoskeletal Research | 000 | 1 | NIH | 8/11/2026 | $452,620 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K08GM164665 | Hemolysis-Mediated Endothelial Dysfunction and Organ Injury in Trauma | 001 | 1 | NIH | 7/2/2026 | $0 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | R01CA306044 | BDI-fluorescence immunoassay: A rapid noninvasive oral cancer detection test. | 000 | 1 | NIH | 7/1/2026 | $599,841 |
| | 2026 | 2026 | CASE WESTERN RESERVE UNIVERSITY | 10900 EUCLID AVE | CLEVELAND | OH | 44106 | CUYAHOGA | USA | K08GM164665 | Hemolysis-Mediated Endothelial Dysfunction and Organ Injury in Trauma | 000 | 1 | NIH | 6/12/2026 | $192,240 |
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