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mHealth Navigation using SMS Texting to Improve Colorectal Cancer Screening Among Homeless Persons

Award Number: R01MD019112
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/19/2025
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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mHealth Navigation using SMS Texting to Improve Colorectal Cancer Screening Among Homeless Persons - Project Summary: Colorectal cancer (CRC) is among the most common cancers, killing tens of thousands in the US, annually. CRC screening reduces morbidity and mortality by 60%. Despite availability, significant disparities exist in cancer screening for 3.5 million persons experiencing homelessness (PEH) in the US. Socio-economically disadvantaged PEH are overwhelmingly from racial and ethnic minorities; many are in their fifties. Cancer is one of the top two leading causes of death in PEH over 45 years old. PEH have four times the cancer rates and twice the cancer mortality of the general population. There is low cancer health literacy and the rates of CRC screening in PEH is as low as 19.7% vs. 71.6% in the general population. In PEH, the usual route of provider counseling and referral to specialists does not address barriers and is difficult to effectively incorporate into their routine care. Around 85% of PEH reside in shelters. Shelters are among the very few places where PEH congregate, are reachable, and can access health promotion programs. Patient navigation is widely accepted and tested in improving cancer screening among minorities. mHealth strategies have been tested in the general as well as PEH populations to improve access to care. mHealth-based navigation for cancer screening has not been tested in PEH. This proposal seeks to evaluate the extent to which an SMS text-based patient navigation for CRC screening will address some of the barriers to and improve CRC screening among PEH. A streamlined approach will be carried out through an SMS texting strategy in the shelter-clinics of a community organization serving PEH, Project Renewal, in NYC: to explain cancer risks and screening options, provide test instructions and support, identify and address barriers to screening, answer questions and concerns, make appointments for screening, support screening completion, provide post-screen counselling, and obtain test results to complete screening loop. The specific aims include; AIM 1) to evaluate the effect of 6- month SMS text-based patient navigation for CRC screening (INT) versus an attention control (CL) of general health promotion on the completed rates of CRC screening using a randomized trial design in shelter-clinics in New York City (NYC): Hypothesis 1) among PEH age 45-75 not up-to-date with CRC screen, those randomized to the INT (n=294) will have higher CRC screening rates in the magnitude of 10 percentage point, compared to those randomized to the CL (n=294) at 6 months post-enrollment; AIM 2) to evaluate perceptions, attitudes and experiences of PEH (n=50), providers and staff (n=20) on SMS texts navigation for CRC screening in shelter-clinics using semi-structured interviews; AIM 3) to evaluate perceptions and attitudes of program staff (n=20) from agencies servicing PEH at the NYC and national levels on challenges and opportunities of implementing SMS text-based navigation for cancer care and control in shelter system using semi-structured interviews. In this controlled trial, individual level randomization will be employed in shelter- clinics. The primary outcome is CRC screening (completed colonoscopy/FIT/mt-sDNA) at 6 months.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2027 ( Subtotal = $0 )
2027	2025	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Minority Health and Health Disparities Research	000	1	10/14/2026	NEW	$0
														Subtotal = $0

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Minority Health and Health Disparities Research	000	1	5/12/2026	NEW	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $1,372,725 )
2025	2025	GEORGE WASHINGTON UNIVERSITY (THE)	1918 F ST NW	WASHINGTON	DC	20052	DISTRICT OF COLUMBIA	USA	Minority Health and Health Disparities Research	000	1	9/19/2025	NEW	$1,372,725
														Subtotal = $1,372,725

Grand Total All Awards = $1,372,725

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mHealth Navigation using SMS Texting to Improve Colorectal Cancer Screening Among Homeless Persons

Award Number: R01MD019112

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/19/2025

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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