Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Distributed knowledge-based platform for radiotherapy plan quality control

Award Number: R01HS025440
ORGANIZATION: AGENCY FOR HEALTH CARE RESEARCH AND QUALITY
OPDIV: AHRQ
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/11/2018
PERIOD OF PERFORMANCE END DATE: 03/31/2024

Group Awards By:

View Award Description

Distributed knowledge-based platform for radiotherapy plan quality control - ABSTRACT Many recent studies focused on radiotherapy treatment plan quality have begun to quantify what clinicians have long understood: even “optimized” radiotherapy is no guarantee of a truly optimal treatment plan for every patient. Plan quality deficiencies have been shown to put a significant proportion of patients who should have been at low risk of radiation-induced complications at much higher risk for poor outcome. Available research clearly demonstrates a link between radiation provider volume and survival, which emphasizes the importance of quality radiation delivery. Radiation providers in rural or community practices by nature see a wide variety of cases, with lower provider volume for each individual disease site. Through no fault of their own, physician and non-physician practitioners at these rural and community centers could be inadvertently and systematically delivering low quality radiotherapy to their patients simply due to the fact that no platform currently exists that could benchmark their practice against a distributed, externally-validated plan quality control system. Our research team has developed, tested, and clinically-implemented an important tool to combat radiotherapy plan quality deficiencies known as knowledge-based planning (KBP). Knowledge-based planning relies on the use of statistical learning techniques that analyzed a plurality of prior treatments to discover patient-specific anatomical features can be precisely correlated to high quality radiation dose delivery. Unfortunately, the clinical use of KBP has been limited to a handful of high-volume academic centers and, without some external mechanism to increase utilization, its use is not likely to expand significantly to rural and community centers because of the lack of any billing code associated with its use. To provide just such an external mechanism, we intend to build ORBITeR (On-line Real-time Benchmarking Informatics Technology for Radiotherapy), a freely available, on-line knowledge-based radiotherapy plan quality control system. ORBITeR will allow clinicians to obtain automatic and immediate feedback on the quality of any individual treatment plan prior to treatment. We will develop a KBP-driven plan analysis system on a HIPAA-compliant web-based platform designed to give users real- time radiotherapy plan quality feedback. To provide real-time feedback to clinical users, we will develop reporting modules on the ORBITeR system that provide patient-specific feedback on the quality of the intended treatment plan using already-validated head-and-neck, brain, prostate, cervix, lung, pancreas, and liver cancer knowledge-based models. We then will disseminate and evaluate the effectiveness of the ORBITeR plan quality resource among the greater radiation oncology community. Finally, we will develop a quality analytics system to conduct widespread plan quality and patterns of care study across submitting sites on the ORBITeR system. .


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Research on Healthcare Costs, Quality and Outcomes	000	5	2/16/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $374,577 )
2022	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Research on Healthcare Costs, Quality and Outcomes	000	5	3/28/2022	NON-COMPETING CONTINUATION	$374,577
														Subtotal = $374,577

Issue Date FY: 2021 ( Subtotal = $374,613 )
2021	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Research on Healthcare Costs, Quality and Outcomes	000	4	3/10/2021	NON-COMPETING CONTINUATION	$374,613
														Subtotal = $374,613

Issue Date FY: 2020 ( Subtotal = $374,612 )
2020	2020	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Research on Healthcare Costs, Quality and Outcomes	000	3	2/18/2020	NON-COMPETING CONTINUATION	$374,612
														Subtotal = $374,612

Issue Date FY: 2019 ( Subtotal = $374,612 )
2019	2019	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Research on Healthcare Costs, Quality and Outcomes	000	2	3/26/2019	NON-COMPETING CONTINUATION	$374,612
														Subtotal = $374,612

Issue Date FY: 2018 ( Subtotal = $382,363 )
2018	2018	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR DEPT 621	LA JOLLA	CA	92093	SAN DIEGO	USA	Research on Healthcare Costs, Quality and Outcomes	000	1	6/11/2018	NEW	$382,363
														Subtotal = $382,363

Grand Total All Awards = $1,880,777

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Distributed knowledge-based platform for radiotherapy plan quality control

Award Number: R01HS025440

ORGANIZATION: AGENCY FOR HEALTH CARE RESEARCH AND QUALITY

OPDIV: AHRQ

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/11/2018

PERIOD OF PERFORMANCE END DATE: 03/31/2024

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer