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CAMELLIA Cohort: A longitudinal study to understand sexual health and prevention among women in Alabama

Award Number: R01HD110097
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/08/2022
PERIOD OF PERFORMANCE END DATE: 08/31/2027

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CAMELLIA Cohort: A longitudinal study to understand sexual health and prevention among women in Alabama - Abstract Despite the availability of effective HIV prevention tools such as pre-exposure prophylaxis (PrEP), significant disparities persist among communities of color, particularly among women in the Deep South where the rate of HIV diagnosis is fourteen-times higher for Black women compared to White women. Current literature supports that alcohol use is associated with condomless sex and increased number of sexual partners, which may predict greater likelihood of STI/HIV acquisition among Southern Black women. The proposal takes advantage of a dynamic and innovative collaboration of experienced HIV-prevention investigators from the University of Alabama-Birmingham, University of North Carolina-Chapel Hill, Centers for AIDS Research, and the Alabama Department of Public Health (ADPH). In the parent Camellia Cohort, a population-based approach is used to establish a geographically representative cohort of cis- and trans-gender women (‘Camellia Cohort,’ N = 800) at significant risk for future HIV acquisition, based on recent gonorrhea or syphilis infection, across the state of Alabama (AL), highlighted as a geographic hotspot by the federal Ending the HIV Epidemic strategy, to better understand factors associated with risk of STI and HIV diagnosis and predictors for PrEP use. Leveraging current enrollment into this cohort, we will recruit a subset of women to assess the following aims: 1) describe subjective and objective measures of alcohol use in a cohort of women vulnerable to HIV and living in AL by consenting 200 women form our parent study to self-collect alcohol biomarkers; 2) evaluated the association of objectively measured alcohol use with a) incidence of STI and b) PrEP uptake and 3) explore the acceptability and feasibility of biomarker evaluation among a cohort of women vulnerable to HIV by interviewing women who consented to enroll in the supplemental study and those who did not (n = 12, each arm). Study findings will provide updated estimates of how alcohol use impacts health outcomes and HIV prevention behaviors while also providing critical information regarding how best to collect these data from women. Our data measures will harmonize measures across the AWARE-funded projects providing the opportunity to provide data for community partners launching initiatives to promote a reduction in HIV/STI incidence.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $1,177,645 )
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Child Health and Human Development Extramural Research	000	3	8/19/2024	NON-COMPETING CONTINUATION	$1,029,145
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Child Health and Human Development Extramural Research	002	3	9/26/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Child Health and Human Development Extramural Research	001	3	8/26/2024	SUPPLEMENT FOR EXPANSION	$148,500
														Subtotal = $1,177,645

Issue Date FY: 2023 ( Subtotal = $1,211,161 )
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Child Health and Human Development Extramural Research	001	2	9/20/2023	NON-COMPETING CONTINUATION	$0
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Child Health and Human Development Extramural Research	000	2	8/16/2023	NON-COMPETING CONTINUATION	$1,211,161
														Subtotal = $1,211,161

Issue Date FY: 2022 ( Subtotal = $832,281 )
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Child Health and Human Development Extramural Research	000	1	9/9/2022	NEW	$832,281
														Subtotal = $832,281

Grand Total All Awards = $3,221,087

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CAMELLIA Cohort: A longitudinal study to understand sexual health and prevention among women in Alabama

Award Number: R01HD110097

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/08/2022

PERIOD OF PERFORMANCE END DATE: 08/31/2027

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