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An Integrative Longitudinal Analysis of Neural Rhythms in Early Development

Award Number: R01HD104945
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/01/2022
PERIOD OF PERFORMANCE END DATE: 04/30/2028

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An Integrative Longitudinal Analysis of Neural Rhythms in Early Development - PROJECT SUMMARY / ABSTRACT Our investigation is a developmental cognitive neuroscience examination of neural processing during early development. Brain electrical activity consists of multiple, co-occurring oscillatory rhythms that underlie functions critical to simple and complex brain processes. Spatiotemporal characteristics, functional properties, neural generators, and psychological correlates characterize these individual oscillatory rhythms in adult research. These neural signatures are essential for our understanding of brain processes involved in early self-regulatory cognitive and affective processes. Methods for examining brain systems and their oscillatory signals in infants and children, however, have long been non-systematic, lacking the level of standardization, sophistication, and scientific rigor seen in the adult research literature. There is a need for research that characterizes early brain functioning in typically developing infants and young children because it allows scientists to distinguish individual differences in development from at-risk trajectories. Our goal is to provide the first comprehensive and systematic analysis of longitudinal changes in EEG rhythms across infancy and early childhood. Our systematic examination of multiple oscillatory rhythms (delta, theta, alpha/mu, beta) will enhance understanding of their frequency signatures, spatial topographies, and functional properties, all within a developmental time course. We will address three research aims. 1) We will identify and compare developmentally appropriate techniques of characterizing neural oscillatory rhythms. 2) We will characterize ontogenetic changes in neural oscillatory rhythms and their interactions. 3) We will determine whether individual differences in neural oscillation parameters and their developmental trajectories are related to developmental outcomes.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $634,983 )
2025	2025	VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY	300 TURNER ST NW	BLACKSBURG	VA	24060	MONTGOMERY	USA	Child Health and Human Development Extramural Research	000	3	6/17/2025	NON-COMPETING CONTINUATION	$634,983
														Subtotal = $634,983

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY	300 TURNER ST NW	BLACKSBURG	VA	24060	MONTGOMERY	USA	Child Health and Human Development Extramural Research	000	2	9/4/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $635,630 )
2023	2023	VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY	300 TURNER ST NW	BLACKSBURG	VA	24060	MONTGOMERY	USA	Child Health and Human Development Extramural Research	000	2	6/6/2023	NON-COMPETING CONTINUATION	$635,630
														Subtotal = $635,630

Issue Date FY: 2022 ( Subtotal = $644,615 )
2022	2022	VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY	300 TURNER ST NW STE 4200	BLACKSBURG	VA	24061	MONTGOMERY	USA	Child Health and Human Development Extramural Research	000	1	7/1/2022	NEW	$644,615
														Subtotal = $644,615

Grand Total All Awards = $1,915,228

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An Integrative Longitudinal Analysis of Neural Rhythms in Early Development

Award Number: R01HD104945

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/01/2022

PERIOD OF PERFORMANCE END DATE: 04/30/2028

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