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 | Issue Date FY: 2024 ( Subtotal = $19,044,245 ) (Continued on the next page) |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21EB031547 | Developing wearable OPM-MEG to assess brain function in mother-infant dyads during social interactions | 000 | 3 | NIH | 12/19/2023 | $183,600 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AA029135 | Longitudinal Study of Recovery: Psychosocial Functioning, Relapse, and Neuro-Behavioral Markers | 000 | 3 | NIH | 2/7/2024 | $631,719 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AG077783 | Exercise-Induced Mitophagy In Hippocampal Neurons Against AD | 002 | 3 | NIH | 1/19/2024 | $496,201 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK132566 | A leptin-responsive lateral hypothalamus to ventrolateral periaqueductal gray circuit for palatable food overconsumption | 000 | 3 | NIH | 3/28/2024 | $390,288 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI164100 | Use of NLP to Extract Risk Indicators for Immunologic Disease from the Text of EHRs (UNIITE) | 001 | 3 | NIH | 2/5/2024 | $152,763 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK135410 | Water Intake and Weight Control in Older Adults | 000 | 2 | NIH | 1/31/2024 | $604,754 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01NS115971 | The impact of interstitial fluid flow on CAR T cell trafficking, distribution, and efficacy | 001 | 4 | NIH | 4/9/2024 | $45,989 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01NS115971 | The impact of interstitial fluid flow on CAR T cell trafficking, distribution, and efficacy | 000 | 4 | NIH | 3/27/2024 | $591,303 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01GM141096 | A low-input microfluidic ChIRP-seq technology for studying endogenous lncRNA binding | 000 | 4 | NIH | 3/13/2024 | $236,035 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01NS121103 | Novel mechanisms suppressing the pro-resolving phenotype of peripheral innate immunity following traumatic brain injury | 000 | 4 | NIH | 4/3/2024 | $388,000 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DA051573 | Social influences on choices in adolescent substance use | 000 | 4 | NIH | 12/22/2023 | $615,299 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01GM140042 | Combining modeling and experiments to study the evolution of cells with altered ploidy | 000 | 4 | NIH | 12/5/2023 | $316,397 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01NS120746 | TrkB.T1 signaling in astrocytes | 001 | 4 | NIH | 4/16/2024 | $22,342 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01NS120746 | TrkB.T1 signaling in astrocytes | 000 | 4 | NIH | 11/13/2023 | $287,272 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01MH122948 | Direct sub-second measurement of neuromodulator signaling during risky decision-making | 000 | 5 | NIH | 2/24/2024 | $592,846 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01MH122414 | The sex-specific role of degradation-specific protein polyubiquitination in fear memory formation | 001 | 4 | NIH | 11/7/2023 | $28,533 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01MH122414 | The sex-specific role of degradation-specific protein polyubiquitination in fear memory formation | 000 | 4 | NIH | 10/26/2023 | $347,527 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01MH122414 | The sex-specific role of degradation-specific protein polyubiquitination in fear memory formation | 002 | 4 | NIH | 12/4/2023 | $79,633 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01GM140130 | Demonstrate the molecular receptor and functions of dorsal organ warm cells in flies | 000 | 4 | NIH | 11/13/2023 | $302,400 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL156667 | Perm1 is a Novel Regulator of Cardiac Energetics and Function | 001 | 4 | NIH | 12/22/2023 | $77,343 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL156667 | Perm1 is a Novel Regulator of Cardiac Energetics and Function | 000 | 4 | NIH | 11/9/2023 | $418,291 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R37CA222563 | Interstitial Fluid Flow Regulates Glioma Cell Invasion | 004 | 7 | NIH | 4/17/2024 | $26,769 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R37CA222563 | Interstitial Fluid Flow Regulates Glioma Cell Invasion | 002 | 7 | NIH | 11/7/2023 | $481,877 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R37CA222563 | Interstitial Fluid Flow Regulates Glioma Cell Invasion | 003 | 7 | NIH | 11/29/2023 | $0 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01NS131858 | Functions for CA1 axo-axonic and basket interneurons in sharp-wave ripple replay and spatial memory | 000 | 1 | NIH | 2/29/2024 | $406,830 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI180524 | Defining the atypical quorum sensing system of Brucella spp. | 000 | 1 | NIH | 1/4/2024 | $171,329 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R00AG070104 | Perilipin 5: Linking lipid droplets to nutrient sensing and healthy aging | 000 | 3 | NIH | 1/17/2024 | $249,000 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01ES035013 | Evaluation of Pb-induced perturbations in the central and enteric nervous system | 000 | 1 | NIH | 12/22/2023 | $395,403 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R03AI182773 | Vector-virus determinants of the public health risk of La Crosse virus in the Northeastern USA | 000 | 1 | NIH | 1/22/2024 | $72,000 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA289124 | Overcoming therapy resistance in melanoma | 000 | 1 | NIH | 4/4/2024 | $214,505 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | F31AI181555 | The natural release of Treponema pallidum peptidoglycan as a pathogenic determinant of syphilis | 000 | 1 | NIH | 3/8/2024 | $42,502 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI182899 | Elucidating the regulatory mechanism of a Brucella-specific small RNA required for virulence | 000 | 1 | NIH | 1/9/2024 | $175,808 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01ES035813 | Does lead (Pb) poisoning impair brain development by affecting how thyroid hormone gets into the brain? | 000 | 1 | NIH | 4/15/2024 | $320,000 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL168559 | The role of REDD1 in insulin-mediated transcription | 000 | 1 | NIH | 2/9/2024 | $473,317 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL169610 | Therapeutic Targeting of Voltage Gated Sodium Channel Autoregulation | 000 | 1 | NIH | 3/12/2024 | $713,336 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI179614 | A gerbil model to delineate the mechanism of hepatitis E virus extrahepatic pathogenesis | 000 | 1 | NIH | 11/9/2023 | $360,000 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21EB035278 | Ultrasound-guided robotic histotripsy array system for non-invasive precise and complete ablation of soft tissue sarcoma | 000 | 1 | NIH | 2/8/2024 | $180,000 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA274439 | Optimization of High Frequency Irreversible Electroporation (H-FIRE) for tumor ablation and immune system activation in pancreatic cancer applications | 001 | 2 | NIH | 4/16/2024 | $27,838 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA274439 | Optimization of High Frequency Irreversible Electroporation (H-FIRE) for tumor ablation and immune system activation in pancreatic cancer applications | 000 | 2 | NIH | 3/8/2024 | $501,108 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R35GM149565 | How mRNA features of cell cycle genes support proper cell division | 000 | 2 | NIH | 4/2/2024 | $332,716 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AT012247 | High resolution interrogation of the insula in mechanisms of chronic pain | 000 | 2 | NIH | 1/29/2024 | $217,623 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21HL165296 | A Tissue-Specific Soluble Platelet-Derived Growth Factor Receptor-beta Isoform Retains Functional Capacity | 000 | 2 | NIH | 2/28/2024 | $200,000 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | F31CA271763 | Understanding how variations in nuclear size after whole genome doubling affect tumorigenesis | 000 | 2 | NIH | 3/20/2024 | $41,943 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R03AI171469 | An innovative and straightforward approach to construct and manipulate viral infectious clones | 000 | 2 | NIH | 2/6/2024 | $67,808 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL159097 | Arrhythmia Mechanisms Modulated by Intercalated Disc Extracellular Nanodomains | 000 | 2 | NIH | 2/29/2024 | $567,907 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI172133 | Modulation of innate immune exhaustion during sepsis | 000 | 2 | NIH | 1/12/2024 | $489,421 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI174052 | Haplotype-resolved genome assemblies and chromosomal rearrangements in arboviral vector Aedes albopictus | 000 | 2 | NIH | 10/25/2023 | $169,113 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01MH131820 | Mechanisms and significance of programmed cell death in hypothalamic CRH neurons | 000 | 2 | NIH | 10/19/2023 | $360,000 |
| | 2024 | 2024 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK132389 | Ultra-processed food reward: neural and metabolic factors | 000 | 2 | NIH | 1/30/2024 | $411,176 |
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