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 | Issue Date FY: 2025 ( Subtotal = $46,934,425 ) (Continued on the next page) |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI180326 | In vivo production of Staphylococcus aureus extracellular membrane vesicles | 001 | 2 | NIH | 4/18/2025 | $201,250 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R37AI179614 | A gerbil model to delineate the mechanism of hepatitis E virus extrahepatic pathogenesis | 000 | 2 | NIH | 11/6/2024 | $388,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DA061024 | Neurobehavioral and Psychosocial Predictors of Health Risk Behaviors in Adolescence and Young Adulthood | 000 | 2 | NIH | 6/4/2025 | $835,956 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AG071661 | Interstitial fluid flow in Alzheimer's Disease Progression | 002 | 3 | NIH | 6/10/2025 | $53,384 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AG071661 | Interstitial fluid flow in Alzheimer's Disease Progression | 001 | 3 | NIH | 5/2/2025 | $600,579 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL169610 | Therapeutic Targeting of Voltage Gated Sodium Channel Autoregulation | 001 | 2 | NIH | 7/16/2025 | $69,834 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL169610 | Therapeutic Targeting of Voltage Gated Sodium Channel Autoregulation | 000 | 2 | NIH | 4/23/2025 | $628,502 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01ES035813 | Does lead (Pb) poisoning impair brain development by affecting how thyroid hormone gets into the brain? | 000 | 2 | NIH | 3/4/2025 | $320,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | K02AG088474 | Neuromuscular adaptation to exercise in Alzheimer's Disease | 000 | 1 | NIH | 6/23/2025 | $152,237 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AG080358 | Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults with Prediabetes | 001 | 2 | NIH | 4/28/2025 | $20,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AG080358 | Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults with Prediabetes | 000 | 2 | NIH | 11/22/2024 | $180,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI176922 | Continuum of Immune Responses to Cryptococcus neoformans | 002 | 4 | NIH | 4/11/2025 | $765,843 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI183178 | Determinants of acute and persistent Zika virus shedding in semen | 000 | 2 | NIH | 4/15/2025 | $230,404 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R00NS117657 | Context-dependent neural processing of leg proprioception in Drosophila | 000 | 5 | NIH | 8/1/2025 | $223,499 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01MH137465 | Thalamo-hippocampal interplay in early life trauma-induced aggression | 000 | 1 | NIH | 6/24/2025 | $592,831 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01NS129820 | Stress Hormone Regulation of HSV1 and HSV2 in Autonomic and Sensory Neurons | 000 | 4 | NIH | 8/13/2025 | $385,513 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK133823 | A gut-brain interaction controlling reward learning | 000 | 4 | NIH | 6/30/2025 | $364,794 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | K01AI168452 | Mentored Research (K01) Integrative Spatial Epidemiology Study of Wildlife Rabies Spillover | 000 | 3 | NIH | 6/13/2025 | $125,125 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK134401 | Discovery and characterization of a novel natural product for the treatment of both diabetes and obesity | 000 | 3 | NIH | 6/24/2025 | $476,912 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DA054216 | An Experimental Medicine Approach for the Mechanistic Understanding of Cocaine Use Disorder: Reinforcer Pathology | 001 | 4 | NIH | 4/24/2025 | $691,038 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R35GM146740 | Unlocking the biomedical potential of microbial symbionts from complex ecosystems | 000 | 4 | NIH | 4/15/2025 | $385,537 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | T32ES033959 | Rural Environmental Health Training Program | 000 | 3 | NIH | 6/13/2025 | $127,345 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL163948 | Novel mechanisms for the generation of resolving monocytes | 000 | 4 | NIH | 3/28/2025 | $390,405 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01NS131858 | Functions for CA1 axo-axonic and basket interneurons in sharp-wave ripple replay and spatial memory | 000 | 2 | NIH | 3/11/2025 | $340,599 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA274439 | Optimization of High Frequency Irreversible Electroporation (H-FIRE) for tumor ablation and immune system activation in pancreatic cancer applications | 001 | 3 | NIH | 5/22/2025 | $51,686 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA274439 | Optimization of High Frequency Irreversible Electroporation (H-FIRE) for tumor ablation and immune system activation in pancreatic cancer applications | 000 | 3 | NIH | 3/12/2025 | $465,187 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK135410 | Water Intake and Weight Control in Older Adults | 000 | 3 | NIH | 2/28/2025 | $598,545 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK132389 | Ultra-processed food reward: neural and metabolic factors | 000 | 3 | NIH | 2/17/2025 | $416,245 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI099250 | Molecular mechanism of juvenile hormone action in mosquito reproduction | 000 | 9 | NIH | 2/28/2025 | $387,570 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R35GM160046 | Regulation of canonical and non-canonical substrates of histone lysine methyltransferases | 000 | 1 | NIH | 7/23/2025 | $442,750 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA297765 | Underlying vasculature and perivasculature direct fluid flow in and around tumors | 000 | 1 | NIH | 7/30/2025 | $411,583 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01EB036654 | Wearable magnetoencephalography for studying parent-infant interactions | 000 | 1 | NIH | 7/23/2025 | $567,977 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA296742 | Leveraging combination histotripsy tumor ablation and N-dihydrogalactochitosan immunostimulation to advance osteosarcoma therapy | 000 | 1 | NIH | 7/23/2025 | $419,080 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA269811 | Deploying Histotripsy Based Tumor Ablation Strategies to Treat Pancreatic Cancer | 001 | 4 | NIH | 5/22/2025 | $37,583 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA269811 | Deploying Histotripsy Based Tumor Ablation Strategies to Treat Pancreatic Cancer | 000 | 4 | NIH | 3/5/2025 | $338,245 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI187428 | Expanding Safe Water Access to Improve Health Outcomes in Appalachia: The Rural Water Filtration and Health (RWELL) Trial | 000 | 1 | NIH | 7/23/2025 | $832,818 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI194034 | Impact of BDGR-49 treatment on VEEV induced neurological sequelae | 000 | 1 | NIH | 8/11/2025 | $452,769 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA289124 | Overcoming therapy resistance in melanoma | 001 | 2 | NIH | 5/22/2025 | $17,680 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA289124 | Overcoming therapy resistance in melanoma | 000 | 2 | NIH | 3/3/2025 | $159,129 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI134636 | Impact of Cryptococcus titan cells on pathogenesis | 001 | 7 | NIH | 5/9/2025 | $721,902 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21EB037927 | Focused Ultrasound Therapies for the Non-Invasive Treatment of Tendinopathies | 000 | 1 | NIH | 8/14/2025 | $428,578 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI188287 | Creating an improved oncolytic virus through directed evolution and virus-driven expression of a cancer-targeting peptid | 000 | 1 | NIH | 7/23/2025 | $414,482 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI186059 | Mechanistic studies of the complex regulation of the signaling histidine kinase GacS from Pseudomonas aeruginosa | 000 | 1 | NIH | 7/23/2025 | $422,355 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA294049 | Generalized and Cancer-Related Episodic Future Thinking for Smoking Cessation: Proof-of-Concept and Feasibility Testing | 000 | 1 | NIH | 8/8/2025 | $395,248 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01MH122512 | Sub-second neurochemistry of error signals and affective processing in depression | 000 | 4 | NIH | 3/11/2025 | $649,886 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK141764 | Sub-second catecholamine dynamics underlying food reward in humans | 000 | 1 | NIH | 2/28/2025 | $696,329 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA266966 | Experimental Tobacco Marketplace: Forecasting the Impact of Novel Tax Proposals | 001 | 4 | NIH | 8/8/2025 | $654,123 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | T32GM156676 | Virginia Tech Initiative to Maximize Student Development | 001 | 1 | NIH | 4/25/2025 | $0 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | T32GM156676 | Virginia Tech Initiative to Maximize Student Development | 000 | 1 | NIH | 1/31/2025 | $279,245 |
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