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 | Issue Date FY: 2025 ( Subtotal = $53,953,572 ) (Continued on the next page) |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R00NS130463 | Defining a Dystonia Specific Spiking Signature in Cerebellar Nuclei Cells | 000 | 3 | NIH | 8/22/2025 | $249,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK135410 | Water Intake and Weight Control in Older Adults | 000 | 3 | NIH | 2/28/2025 | $598,545 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01GM140130 | Demonstrate the molecular receptor and functions of dorsal organ warm cells in flies | 001 | 5 | NIH | 8/12/2025 | $33,600 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01GM140130 | Demonstrate the molecular receptor and functions of dorsal organ warm cells in flies | 000 | 5 | NIH | 11/21/2024 | $302,400 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21EB035655 | A pulse-driven micropump for continuous drug delivery | 000 | 2 | NIH | 4/22/2025 | $204,788 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA289288 | Image-guided Histotripsy System for Complete, Uniform, and Non-Invasive Ablation of Heterogeneous Osteosarcoma Tumors | 001 | 2 | NIH | 5/22/2025 | $63,244 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA289288 | Image-guided Histotripsy System for Complete, Uniform, and Non-Invasive Ablation of Heterogeneous Osteosarcoma Tumors | 000 | 2 | NIH | 4/15/2025 | $569,206 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DA061024 | Neurobehavioral and Psychosocial Predictors of Health Risk Behaviors in Adolescence and Young Adulthood | 000 | 2 | NIH | 6/4/2025 | $835,956 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R37AI179614 | A gerbil model to delineate the mechanism of hepatitis E virus extrahepatic pathogenesis | 000 | 2 | NIH | 11/6/2024 | $388,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI180326 | In vivo production of Staphylococcus aureus extracellular membrane vesicles | 003 | 2 | NIH | 5/6/2025 | $208,887 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI180326 | In vivo production of Staphylococcus aureus extracellular membrane vesicles | 001 | 2 | NIH | 4/18/2025 | $201,250 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AG071661 | Interstitial fluid flow in Alzheimer's Disease Progression | 002 | 3 | NIH | 6/10/2025 | $53,384 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AG071661 | Interstitial fluid flow in Alzheimer's Disease Progression | 001 | 3 | NIH | 5/2/2025 | $600,579 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | M0154905 | Behavioral Health Workforce Education and Training Program | 01 | 1 | HRSA | 9/5/2025 | $0 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | M0154905 | Behavioral Health Workforce Education and Training Program | 00 | 1 | HRSA | 6/18/2025 | $350,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | K01CA279490 | Development of abuse liability-based tobacco tax proposals: Experimental impact on tobacco-related socioeconomic cancer health disparities | 001 | 3 | NIH | 8/15/2025 | $136,448 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01ES035813 | Does lead (Pb) poisoning impair brain development by affecting how thyroid hormone gets into the brain? | 000 | 2 | NIH | 3/4/2025 | $320,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL169610 | Therapeutic Targeting of Voltage Gated Sodium Channel Autoregulation | 001 | 2 | NIH | 7/16/2025 | $69,834 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01HL169610 | Therapeutic Targeting of Voltage Gated Sodium Channel Autoregulation | 000 | 2 | NIH | 4/23/2025 | $628,502 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AG080358 | Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults with Prediabetes | 001 | 2 | NIH | 4/28/2025 | $20,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AG080358 | Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults with Prediabetes | 000 | 2 | NIH | 11/22/2024 | $180,000 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI176922 | Continuum of Immune Responses to Cryptococcus neoformans | 002 | 4 | NIH | 4/11/2025 | $765,843 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI183178 | Determinants of acute and persistent Zika virus shedding in semen | 000 | 2 | NIH | 4/15/2025 | $230,404 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK133823 | A gut-brain interaction controlling reward learning | 000 | 4 | NIH | 6/30/2025 | $364,794 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | K01AI168452 | Mentored Research (K01) Integrative Spatial Epidemiology Study of Wildlife Rabies Spillover | 000 | 3 | NIH | 6/13/2025 | $125,125 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK134401 | Discovery and characterization of a novel natural product for the treatment of both diabetes and obesity | 000 | 3 | NIH | 6/24/2025 | $476,912 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R35GM146740 | Unlocking the biomedical potential of microbial symbionts from complex ecosystems | 000 | 4 | NIH | 4/15/2025 | $385,537 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DA054216 | An Experimental Medicine Approach for the Mechanistic Understanding of Cocaine Use Disorder: Reinforcer Pathology | 001 | 4 | NIH | 4/24/2025 | $691,038 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI187574 | Chromosomal Rearengements in Aedes aegypti | 000 | 1 | NIH | 8/29/2025 | $611,861 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | RF1AG075000 | Losing specificity: the role of the locus coeruleus in age-related distractibility | 000 | 4 | NIH | 9/4/2025 | $1,394,771 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01MH122512 | Sub-second neurochemistry of error signals and affective processing in depression | 000 | 4 | NIH | 3/11/2025 | $649,886 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK141764 | Sub-second catecholamine dynamics underlying food reward in humans | 000 | 1 | NIH | 2/28/2025 | $696,329 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA294049 | Generalized and Cancer-Related Episodic Future Thinking for Smoking Cessation: Proof-of-Concept and Feasibility Testing | 000 | 1 | NIH | 8/8/2025 | $395,248 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI099250 | Molecular mechanism of juvenile hormone action in mosquito reproduction | 000 | 9 | NIH | 2/28/2025 | $387,570 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA269811 | Deploying Histotripsy Based Tumor Ablation Strategies to Treat Pancreatic Cancer | 001 | 4 | NIH | 5/22/2025 | $37,583 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01CA269811 | Deploying Histotripsy Based Tumor Ablation Strategies to Treat Pancreatic Cancer | 000 | 4 | NIH | 3/5/2025 | $338,245 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01AI187428 | Expanding Safe Water Access to Improve Health Outcomes in Appalachia: The Rural Water Filtration and Health (RWELL) Trial | 000 | 1 | NIH | 7/23/2025 | $832,818 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R03HD119157 | A Behavioral and Neural Investigation of Young Children's Attention and Comprehension on Interactive Video Viewing Platforms | 000 | 1 | NIH | 8/28/2025 | $150,803 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA289124 | Overcoming therapy resistance in melanoma | 001 | 2 | NIH | 5/22/2025 | $17,680 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA289124 | Overcoming therapy resistance in melanoma | 000 | 2 | NIH | 3/3/2025 | $159,129 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI194034 | Impact of BDGR-49 treatment on VEEV induced neurological sequelae | 000 | 1 | NIH | 8/11/2025 | $452,769 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI186059 | Mechanistic studies of the complex regulation of the signaling histidine kinase GacS from Pseudomonas aeruginosa | 000 | 1 | NIH | 7/23/2025 | $422,355 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21AI188287 | Creating an improved oncolytic virus through directed evolution and virus-driven expression of a cancer-targeting peptid | 000 | 1 | NIH | 7/23/2025 | $414,482 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA296742 | Leveraging combination histotripsy tumor ablation and N-dihydrogalactochitosan immunostimulation to advance osteosarcoma therapy | 000 | 1 | NIH | 7/23/2025 | $419,080 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01EB036654 | Wearable magnetoencephalography for studying parent-infant interactions | 000 | 1 | NIH | 7/23/2025 | $567,977 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21CA297765 | Underlying vasculature and perivasculature direct fluid flow in and around tumors | 000 | 1 | NIH | 7/30/2025 | $411,583 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R35GM160046 | Regulation of canonical and non-canonical substrates of histone lysine methyltransferases | 000 | 1 | NIH | 7/23/2025 | $442,750 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R21HL168614 | Development of a novel intracellular targeting nanobody that blocks Cx43-mediated pathological proliferation | 000 | 2 | NIH | 7/2/2025 | $196,678 |
| | 2025 | 2025 | VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | 300 TURNER ST NW | BLACKSBURG | VA | 24060-3359 | MONTGOMERY | USA | R01DK137181 | Blockade of S1P pathway for renal fibrosis therapy | 000 | 2 | NIH | 6/25/2025 | $572,063 |
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