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Gender Nonconformity in Prepubescent Children: A Longitudinal Study

Award Number: R01HD097122
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/21/2019
PERIOD OF PERFORMANCE END DATE: 02/29/2024

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Gender Nonconformity in Prepubescent Children: A Longitudinal Study - PROJECT SUMMARY/ABSTRACT The purpose of this proposed study is to establish a national cohort of prepubertal transgender/gender- nonconforming (TGNC) children (and their parents), and longitudinally observe this cohort to expand the body of empirical knowledge pertaining to gender development and cognition in TGNC children, their mental health symptomology and functioning over time, and how family-initiated social gender transition may predict or alleviate mental health symptoms and/or diagnoses. Participants will be recruited and enrolled either at one of four Gender Centers dedicated to their care (Children's Hospital Los Angeles/University of Southern California; Lurie Children's Hospital of Chicago/Northwestern University; Boston Children's Hospital/Harvard Medical School; Benioff Children's Hospital/University of California San Francisco), and followed over a 2-year observational period, with clinical and behavioral data collected from prepubertal TGNC children and their parents at 6-month intervals. The proposed study will use state-of-the-art measures and utilize statistical advances in person-centered analytical approaches (i.e., latent class analysis and latent transition analysis) to address inconsistencies in prior studies, which have focused primarily on variable-centered approaches. The proposed study leverages the resources of the only NIH-funded network of US-based pediatric gender centers (Grant #R01HD082554), expanding on this current collaboration (studying TGNC adolescents) to include a younger and understudied cohort of prepubertal TGNC children. Together, these sites share a long-term goal and anticipate expanding investigation into a program of research that examines the experiences and needs of TGNC youth from early childhood through early adulthood. This proposal sets up an ideal framework to continue collecting longitudinal data from the cohort recruited for this initial work, as well as understand the additional complexities of this population based on the cohorts recruited in the companion study of peripubertal and pubertal TGNC adolescents (Grant #R01-HD082554).


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $587,367 )
2023	2023	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Child Health and Human Development Extramural Research	002	5	4/14/2023	NON-COMPETING CONTINUATION	$587,367
2023	2022	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Child Health and Human Development Extramural Research	001	4	3/28/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$543,325
2023	2021	CHILDREN'S HOSPITAL LOS ANGELES	4650 W SUNSET BLVD	LOS ANGELES	CA	90027	LOS ANGELES	USA	Child Health and Human Development Extramural Research	000	3	3/28/2023	NON-COMPETING CONTINUATION	-$543,325
														Subtotal = $587,367

Issue Date FY: 2022 ( Subtotal = $625,609 )
2022	2022	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Child Health and Human Development Extramural Research	001	4	9/23/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$625,609
2022	2021	CHILDRENS HOSPITAL LOS ANGELES	4650 W SUNSET BLVD	LOS ANGELES	CA	90027	LOS ANGELES	USA	Child Health and Human Development Extramural Research	000	3	9/23/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $625,609

Issue Date FY: 2021 ( Subtotal = $654,962 )
2021	2021	CHILDRENS HOSPITAL LOS ANGELES	4650 SUNSET BLVD	LOS ANGELES	CA	90027	LOS ANGELES	USA	Child Health and Human Development Extramural Research	001	3	4/15/2021	NON-COMPETING CONTINUATION	$0
2021	2021	CHILDRENS HOSPITAL LOS ANGELES	4650 SUNSET BLVD	LOS ANGELES	CA	90027	LOS ANGELES	USA	Child Health and Human Development Extramural Research	000	3	3/2/2021	NON-COMPETING CONTINUATION	$654,962
														Subtotal = $654,962

Issue Date FY: 2020 ( Subtotal = $682,652 )
2020	2020	CHILDRENS HOSPITAL LOS ANGELES	4650 SUNSET BLVD	LOS ANGELES	CA	90027	LOS ANGELES	USA	Child Health and Human Development Extramural Research	000	2	3/24/2020	NON-COMPETING CONTINUATION	$682,652
														Subtotal = $682,652

Issue Date FY: 2019 ( Subtotal = $776,835 )
2019	2019	CHILDRENS HOSPITAL LOS ANGELES	4650 SUNSET BLVD	LOS ANGELES	CA	90027	LOS ANGELES	USA	Child Health and Human Development Extramural Research	000	1	3/21/2019	NEW	$776,835
2019	2019	CHILDRENS HOSPITAL LOS ANGELES	4650 SUNSET BLVD	LOS ANGELES	CA	90027	LOS ANGELES	USA	Child Health and Human Development Extramural Research	001	1	6/8/2019	NEW	$0
														Subtotal = $776,835

Grand Total All Awards = $3,327,425

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Gender Nonconformity in Prepubescent Children: A Longitudinal Study

Award Number: R01HD097122

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/21/2019

PERIOD OF PERFORMANCE END DATE: 02/29/2024

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