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Administrative Supplement to Promote Re-Entry in Health-Related Research Careers

Award Number: R01GM149693
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2025
PERIOD OF PERFORMANCE END DATE: 06/30/2028

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Administrative Supplement to Promote Re-Entry in Health-Related Research Careers - Project Summary The objective of this administrative supplement application is to promote the re-entry of a postdoctoral fellow into the biomedical workforce after a qualifying hiatus from research activities. The fellow will be engaged in research activities directly supporting one of the specific aims in the parent award, which focuses on the development of new bioorthogonal methods for unveiling chemical reactivity. Specifically, the fellow will focus on developing small, discreet tags that can be incorporated onto bioactive small molecules, inducing a minimal perturbation to the molecule’s physicochemical and target-binding properties. The small tags will then be activated through bioorthogonal chemical reaction to generate a reactive functional group, which can then label proteins in a ligand- dependent manner. The hypothesis is that these systems will feature minimalist probes that have a much smaller footprint than the current enamine N-oxide-based bioorthogonally activated reactive species (BARS) probes while offering comparable specificity in drug target identification. Another major objective of this supplement is the career development of the postdoctoral fellow. The fellow will participate in career development activities at the laboratory, department, and institute levels to ensure that they are able to get back up to speed on the current state of the chemical biology field after experiencing a long hiatus from research activities. The plan is for the fellow to gain skills in protein conjugation and modification so they can ultimately combine those skills with their existing expertise in biomaterials to launch a successful career in chemical biology and biomedical engineering.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $91,964 )
2026	2026	GEORGIA TECH RESEARCH CORP	926 DALNEY ST NW	ATLANTA	GA	30318	FULTON	USA	Biomedical Research and Research Training	000	2	1/23/2026	SUPPLEMENT FOR EXPANSION	$91,964
														Subtotal = $91,964

Issue Date FY: 2025 ( Subtotal = $317,623 )
2025	2025	GEORGIA TECH RESEARCH CORP	926 DALNEY ST NW	ATLANTA	GA	30318	FULTON	USA	Biomedical Research and Research Training	000	2	7/18/2025	NON-COMPETING CONTINUATION	$317,623
														Subtotal = $317,623

Issue Date FY: 2024 ( Subtotal = $317,623 )
2024	2024	GEORGIA TECH RESEARCH CORP	926 DALNEY ST NW	ATLANTA	GA	30318	FULTON	USA	Biomedical Research and Research Training	000	1	8/19/2024	NEW	$317,623
														Subtotal = $317,623

Grand Total All Awards = $727,210

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Administrative Supplement to Promote Re-Entry in Health-Related Research Careers

Award Number: R01GM149693

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2025

PERIOD OF PERFORMANCE END DATE: 06/30/2028

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