Friday, November 14, 2025 11/14/2025

SCISIPBIO: Understanding and Assembling Dream Teams to Conduct Clinical and Translational Science

Award Number: R01GM137410
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/01/2024
PERIOD OF PERFORMANCE END DATE: 11/30/2025

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SCISIPBIO: Understanding and Assembling Dream Teams to Conduct Clinical and Translational Science - We hail individual geniuses, but success in science comes through collaboration (Farrar, 2017). Biomedical breakthroughs come from collaboration that crosses boundaries. Boundaries created by disciplines, organizations, cultures, professions, and demographics. While cross-boundary collaboration in team science has demonstrated benefits, research also suggests they are unlikely to form, and when they do, are prone to coordination costs (Cooke & Hilton, 2015). This research project advances the Science of Team Science by understanding and assembling cross-boundary teams to conduct clinical and translational science. This research enables scholars and policymakers to design and assess dream teams. Toward the aim of understanding, we conduct archival studies of NIH's Clinical & Translational Science Pilot Grant programs at two institutions to reveal the team assembly factors that drive formation and success. Toward the aim of assembling, we leverage a newly developed team recommender system. The fundamental goal is to generate recommendations to shift the composition of teams submitting Pilot Grant applications in particular and cross-boundary scientific teams in general. Insights from this project come at a critical point in time, when cross-boundary science is essential for biomedical research. Toward that aim, this project has two key sources of intellectual merit. First, the research advances the science of team science (Cooke & Hilton, 2015), answering calls to better understand the multilevel determinants of science team success. How are they forming and which ones are performing? Following teams from formation to maturity provide a holistic understanding of the factors driving team formation and performance. Knowing how to better assemble scientific teams has the potential to improve the career productivity of a major source of human capital, and to hasten breakthroughs in biomedical research. Furthermore, not all cross-boundary teams are successful. Previous research provides competing advice for those assembling teams. On the one hand, cross- boundary teams are most likely to produce novel insights (Stvilia et al., 2011; Uzzi et al., 2013), but they are also most likely to suffer process losses from their coordination costs (Cummings & Kiesler, 2007; Cummings et al., 2013). This large scale analysis will allow us to discover patterns that differentiate the kinds of cross-boundary teams who are ultimately successful from those who are not. The second source of intellectual merit is the development of a team recommender system for biomedical scientists to use to assemble cross-boundary teams for Pilot Projects. The Dream Team Builder was specifically mentioned in the NAS report as it builds on NIH-funded VIVO's ontology. We extend this tool to provide team recommendations, and study their effects on team assembly and future performance.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Biomedical Research and Research Training	002	5	1/13/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$66,781
2025	2023	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Biomedical Research and Research Training	001	4	1/13/2025	NON-COMPETING CONTINUATION	-$1
2025	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Biomedical Research and Research Training	000	3	1/13/2025	NON-COMPETING CONTINUATION	-$66,780
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $33,779 )
2024	2023	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Biomedical Research and Research Training	000	4	4/11/2024	NON-COMPETING CONTINUATION	-$124,371
2024	2023	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Biomedical Research and Research Training	001	5	4/12/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$158,150
2024	2023	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Biomedical Research and Research Training	002	5	9/24/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $33,779

Issue Date FY: 2023 ( Subtotal = $124,372 )
2023	2023	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Biomedical Research and Research Training	000	4	11/22/2022	NON-COMPETING CONTINUATION	$124,372
														Subtotal = $124,372

Issue Date FY: 2022 ( Subtotal = $249,976 )
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Biomedical Research and Research Training	000	3	11/18/2021	NON-COMPETING CONTINUATION	$224,978
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Biomedical Research and Research Training	001	3	6/23/2022	NON-COMPETING CONTINUATION	$24,998
														Subtotal = $249,976

Issue Date FY: 2021 ( Subtotal = $248,556 )
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Biomedical Research and Research Training	001	2	2/15/2021	NON-COMPETING CONTINUATION	$24,856
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Biomedical Research and Research Training	000	2	11/11/2020	NON-COMPETING CONTINUATION	$223,700
														Subtotal = $248,556

Issue Date FY: 2020 ( Subtotal = $249,857 )
2020	2020	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Biomedical Research and Research Training	000	1	11/25/2019	NEW	$249,857
														Subtotal = $249,857

Grand Total All Awards = $906,540

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SCISIPBIO: Understanding and Assembling Dream Teams to Conduct Clinical and Translational Science

Award Number: R01GM137410

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/01/2024

PERIOD OF PERFORMANCE END DATE: 11/30/2025

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