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Molecular Neurogenetics of Olfactory Driven Aggression and Social Hierarchy in a Model Insect System

Award Number: R01GM128336
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/16/2018
PERIOD OF PERFORMANCE END DATE: 04/30/2024

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Molecular Neurogenetics of Olfactory Driven Aggression and Social Hierarchy in a Model Insect System - Project Summary Humans and many other animals exhibit a wide variety of social behaviors. Traditionally, primates have been used as research models of human behavior due to their close evolutionary relationship to humans and their highly social behavior. However, the use of primates for such research has significant economic, practical, and ethical drawbacks, and, in that light, it would be useful to find other models for behavioral studies that exhibit complex social behaviors. One potential model that fits both criteria is the extensive family of insects collectively known as the ants, some species of which exhibit highly complex “eusocial” behaviors involving a strict division of labor between sterile workers and reproductive queens. Among ant workers, there is a further division of labor, with different tasks allocated among different castes of workers. Our hypothesis is that caste/colony-specific aggression and social hierarchy reflect and in-part are determined by chemosensory programs dictated largely through odorant receptors and shifts in neuropeptidomic profiles. We will investigate this question in two ant species—Camponotus floridanus and Harpegnathos saltator—that exist in large colonies that are composed of just a few males, and the remainder are females, including one (typically) queen, and numerous workers that engage in caste/colony specific aggressive behaviors such as defense, policing and dueling.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$604 )
2025	2021	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Biomedical Research and Research Training	000	4	11/14/2024	NON-COMPETING CONTINUATION	-$604
														Subtotal = -$604

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2021	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Biomedical Research and Research Training	000	4	3/14/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $313,904 )
2021	2021	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Biomedical Research and Research Training	000	4	4/20/2021	NON-COMPETING CONTINUATION	$313,904
														Subtotal = $313,904

Issue Date FY: 2020 ( Subtotal = $313,904 )
2020	2020	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Biomedical Research and Research Training	000	3	5/22/2020	NON-COMPETING CONTINUATION	$313,904
														Subtotal = $313,904

Issue Date FY: 2019 ( Subtotal = $313,904 )
2019	2019	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Biomedical Research and Research Training	000	2	5/6/2019	NON-COMPETING CONTINUATION	$313,904
														Subtotal = $313,904

Issue Date FY: 2018 ( Subtotal = $313,904 )
2018	2018	VANDERBILT UNIVERSITY, THE	110 21ST AVENUE S STE 800	NASHVILLE	TN	37203	DAVIDSON	USA	Biomedical Research and Research Training	000	1	8/16/2018	NEW	$313,904
														Subtotal = $313,904

Grand Total All Awards = $1,255,012

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Molecular Neurogenetics of Olfactory Driven Aggression and Social Hierarchy in a Model Insect System

Award Number: R01GM128336

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/16/2018

PERIOD OF PERFORMANCE END DATE: 04/30/2024

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