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Beacon Sensors and Telerehabilitation to Assess and Improve use of Devices (BeST-AID) for Low Vision

Award Number: R01EY034627
ORGANIZATION: NATIONAL EYE INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2023
PERIOD OF PERFORMANCE END DATE: 06/30/2028

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Beacon Sensors and Telerehabilitation to Assess and Improve use of Devices (BeST-AID) for Low Vision - Project Summary or Abstract The successful application of magnification devices for reading and daily tasks is predicated on their correct use by individuals with low vision (LV). Barriers related to transportation, geography, and/or health-related concerns often limit LV patients’ ability to attend several in-office training sessions as part of low vision rehabilitation (LVR) to optimize visual function with magnification devices. A promising solution is real-time videoconferencing to provide telerehabilitation, involving remotely delivered LVR services by a LVR provider in-office to a patient at home. Telerehabilitation for LV appears to be feasible and acceptable by both patients and LVR providers, with preliminary evidence that its efficacy for enhancing reading ability may be similar to in-office LVR. However, it has not yet been fully demonstrated whether telerehabilitation is at least as effective as in-office usual care for LV follow-ups. This would be critical information for LV providers for reassurance that either modality is acceptable. Another key issue in LVR is the need for an effective system to continually assess how patients are functioning at home. Ideally this would involve a non-invasive, efficient method to assess when magnifier device abandonment occurs, so that a timely telerehabilitation session can be initiated. Bluetooth low energy (BLE) beacon sensors attached to the handles of magnifiers can collect longitudinal data regarding environmental changes, which might serve as a helpful indicator of magnifier use patterns by LV patients at home. Specifically, we propose to conduct a randomized non-inferiority trial of the potential for telerehabilitation to enhance visual ability by providing remotely-delivered LVR training to use magnification devices and/or visual assistive mobile apps in comparison to in-office usual care LVR. This will provide an evidence basis for whether the effects of two interventions are not clinically and statistically different from each other. This is important to determine if a novel service delivery mode (i.e., telerehabilitation), that might be safer, more resource efficient, convenient, may improve adherence and/or access to care, is at least as effective as a more established approach (i.e., in-office) with proven effectiveness. We aim to show how telehealth services can be made readily accessible to those with LV, as well as the value of annual follow-ups via telerehabilitation. We will determine whether BLE beacon sensor data are valid indicators of hand-held optical magnifier usage by LV patients at home. We anticipate that beacon sensors attached to hand-held optical magnifiers will measure increased temperature and/or humidity when motion is detected. Beacon sensor data will determine if it is feasible to remotely assess when magnifiers are used or abandoned, and if their frequency of use changes following telerehabilitation or in-office LVR. We envision that telerehabilitation can improve patient outcomes as an alternative, effective method for the provision of follow-up LV services. This is a high priority given the increasing prevalence of LV, paucity of LV providers, and barriers to care. Beacon sensors are a novel solution for monitoring LV patients beyond the clinical office visit, which could enhance patient management with timely LV services and evaluation of LV device use.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $359,984 )
2026	2026	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Vision Research	000	4	8/6/2026	NON-COMPETING CONTINUATION	$359,984
														Subtotal = $359,984

Issue Date FY: 2025 ( Subtotal = $359,984 )
2025	2025	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Vision Research	000	3	8/1/2025	NON-COMPETING CONTINUATION	$359,984
														Subtotal = $359,984

Issue Date FY: 2024 ( Subtotal = $541,005 )
2024	2024	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Vision Research	002	2	8/2/2024	SUPPLEMENT FOR EXPANSION	$170,541
2024	2024	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Vision Research	001	2	8/1/2024	NON-COMPETING CONTINUATION	$367,886
2024	2023	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Vision Research	000	1	1/9/2024	NEW	$2,578
														Subtotal = $541,005

Issue Date FY: 2023 ( Subtotal = $424,359 )
2023	2023	UNIVERSITY OF CALIFORNIA, LOS ANGELES	10889 WILSHIRE BLVD STE 700	LOS ANGELES	CA	90024	LOS ANGELES	USA	Vision Research	000	1	9/13/2023	NEW	$424,359
														Subtotal = $424,359

Grand Total All Awards = $1,685,332

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Beacon Sensors and Telerehabilitation to Assess and Improve use of Devices (BeST-AID) for Low Vision

Award Number: R01EY034627

ORGANIZATION: NATIONAL EYE INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2023

PERIOD OF PERFORMANCE END DATE: 06/30/2028

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