Wednesday, July 16, 2025 7/16/2025

Research Resource for Complex Physiologic Signals

Award Number: R01EB030362
ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2007
PERIOD OF PERFORMANCE END DATE: 06/30/2028

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Research Resource for Complex Physiologic Signals - PhysioNet, established in 1999 as the NIH-sponsored Research Resource for Complex Physiologic Signals, has attained a preeminent status among biomedical data and software resources. Its data archive was the first, and remains the world's largest, most comprehensive and widely used repository of time-varying physiologic signals. Its software collection supports exploration and quantitative analyses of its own and other databases by providing a wide range of well-documented, rigorously tested open-source programs. PhysioNet's team of researchers drive the creation and enrichment of: i) data collections that provide comprehensive, multifaceted views of pathophysiology over long time intervals, such as the MIMIC (Medical Information Mart for Intensive Care) Databases of critical care patients; ii) analytic methods for quantification of information encoded in physiologic signals relevant to risk stratification and health status assessment; iii) user interfaces, reference materials and services that add value and improve access to the resource’s data and software, and iv) unique annual signal analysis Challenges focusing on high priority clinical problems, such as early prediction of sepsis, detection and quantification of sleep apnea syndromes from a single lead electrocardiogram (ECG), false alarm detection in the intensive care unit (ICU), continuous fetal ECG monitoring, paroxysmal atrial fibrillation detection and prediction, and predicting the level of neurologic recovery from coma after cardiac arrest. PhysioNet is a proven enabler and accelerator of innovative research by investigators with a diverse range of interests, working on projects made possible by otherwise inaccessible data. PhysioNet's worldwide and growing community of users include researchers, clinicians, educators, trainees, and medical instrument and software developers. The PhysioNet enterprise was recognized with the 2016 Laufman-Greatbatch Award, the highest honor accorded by the Association for the Advancement of Medical Instrumentation (AAMI). PhysioNet Challenges received the 2022 Distinguished Achievement Award for Data Reuse,” as part of the inaugural NIH DataWorks! Prize. PhysioNet has been designated as an NIH/NIBIB sponsored data-sharing repository. Over the next five years, we aim to: 1) magnify PhysioNet’s impact with new data and technology; 2) develop novel computational methodologies to quantify dynamical information of basic and translational value encoded in physiologic signals, and 3) harness the research community through our international Challenges that address key clinical problems, emphasizing the application of artificial intelligence methodologies.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	BETH ISRAEL DEACONESS MEDICAL CENTER, INC.	330 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	17	4/11/2025	COMPETING CONTINUATION	$72,950
2025	2023	BETH ISRAEL DEACONESS MEDICAL CENTER, INC.	330 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	16	4/11/2025	NON-COMPETING CONTINUATION	-$72,950
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $652,827 )
2024	2024	BETH ISRAEL DEACONESS MEDICAL CENTER, INC.	330 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	17	8/13/2024	COMPETING CONTINUATION	$652,827
2024	2023	BETH ISRAEL DEACONESS MEDICAL CENTER, INC.	330 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	16	8/6/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $652,827

Issue Date FY: 2023 ( Subtotal = $722,418 )
2023	2023	BETH ISRAEL DEACONESS MEDICAL CENTER, INC	330 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	16	4/5/2023	NON-COMPETING CONTINUATION	$722,418
														Subtotal = $722,418

Issue Date FY: 2022 ( Subtotal = $722,418 )
2022	2022	BETH ISRAEL DEACONESS MEDICAL CENTER, INC	330 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	15	5/30/2022	NON-COMPETING CONTINUATION	$722,418
														Subtotal = $722,418

Issue Date FY: 2021 ( Subtotal = $1,145,470 )
2021	2021	BETH ISRAEL DEACONESS MEDICAL CENTER, INC	330 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	14	6/17/2021	NON-COMPETING CONTINUATION	$707,970
2021	2021	BETH ISRAEL DEACONESS MEDICAL CENTER, INC	330 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	14	6/17/2021	SUPPLEMENT FOR EXPANSION	$437,500
														Subtotal = $1,145,470

Issue Date FY: 2020 ( Subtotal = $759,918 )
2020	2020	BETH ISRAEL DEACONESS MEDICAL CENTER, INC	330 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	13	7/29/2020	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$759,918
														Subtotal = $759,918

Grand Total All Awards = $4,003,051

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Research Resource for Complex Physiologic Signals

Award Number: R01EB030362

ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2007

PERIOD OF PERFORMANCE END DATE: 06/30/2028

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