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 | Issue Date FY: 2025 ( Subtotal = $2,573,830 ) |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21AI176120 | Development and Characterization of Phage QBeta-Based SARS-CoV-2 RT-qPCR Assay Calibration Standards | 000 | 2 | NIH | 11/6/2024 | $251,570 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AG082016 | Wake-sleep Circuitry in Neurodegenerative Dementias | 000 | 2 | NIH | 11/14/2024 | $777,303 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K08HL161259 | Regulation of endothelial cell phosphatidylserine in thrombosis | 000 | 4 | NIH | 11/14/2024 | $165,024 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | P30HS029762 | Massachusetts Institute for Equity-Focused Learning Health System Science (MIELHSS) | 000 | 2 | AHRQ | 11/18/2024 | $997,446 |
| | 2025 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AG065554 | Scheduled Prophylactic 6-hourly IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients | 000 | 5 | NIH | 11/7/2024 | $0 |
| | 2025 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01GM148745 | Developing programmable RNA writing tools with the novel RNA-guided RNA-targeting CRISPR effector Cas7-11 | 001 | 2 | NIH | 11/14/2024 | $556,500 |
| | 2025 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K23HL150327 | DMGV and the AGXT2 pathway in chronic exercise-induced cardiometabolic adaptations. | 000 | 5 | NIH | 10/11/2024 | $0 |
| | 2025 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01NS120947 | Establishing a Brain Health Index | 000 | 3 | NIH | 10/11/2024 | $161,751 |
| | 2025 | 2023 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01DK089044 | Leptin, GABAergic Neurons and the Feedback / Feedforward Regulation of Energy Balance | 000 | 14 | NIH | 11/13/2024 | -$6,672 |
| | 2025 | 2023 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AT012072 | Tai Chi Exercise and Wearable Feedback Technology to Promote Physical Activity in ACS Survivors | 000 | 2 | NIH | 10/29/2024 | $0 |
| | 2025 | 2023 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K99CA252044 | Therapeutic potential of FANCM for BRCA1-linked cancer | 000 | 2 | NIH | 10/10/2024 | -$84,134 |
| | 2025 | 2023 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R35HL135775 | Thiol Isomerases in Hemostasis and Thrombosis | 000 | 7 | NIH | 10/9/2024 | -$1 |
| | 2025 | 2022 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | U01AA026977 | Alcoholic Hepatitis Clinical and Translational Network Late Phase Clinical Trials and Observational Studies 4/9 | 000 | 6 | NIH | 11/7/2024 | $0 |
| | 2025 | 2022 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HS026215 | Characterizing Opioid-related Adverse Events in Older Adults After Hospital Discharge | 000 | 5 | AHRQ | 11/14/2024 | $0 |
| | 2025 | 2022 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | U01AA026933 | Biomarkers of Disease in Alcoholic Hepatitis | 000 | 6 | NIH | 11/15/2024 | $0 |
| | 2025 | 2022 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01DK112886 | Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis | 000 | 5 | NIH | 11/13/2024 | -$5,099 |
| | 2025 | 2022 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01DK097441 | Molecular Control of Brown Adipose Cell Fate and Energy Metabolism | 000 | 11 | NIH | 11/13/2024 | -$13,237 |
| | 2025 | 2022 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21AG065923 | PGC-1α, Purines and the Postmenopausal Heart | 000 | 2 | NIH | 11/5/2024 | -$2 |
| | 2025 | 2022 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01NS078263 | MECHANISMS OF CSD-EVOKED PERSISTENT ACTIVATION OF MENINGEAL NOCICEPTORS | 000 | 9 | NIH | 10/15/2024 | -$1 |
| | 2025 | 2022 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA212649 | Personalized vaccine for patients with AML | 000 | 6 | NIH | 10/11/2024 | $0 |
| | 2025 | 2021 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21DA051813 | Cocaine induces production of infectious large extracellular vesicles (lEV) and regulates neuro-inflammation | 000 | 2 | NIH | 11/13/2024 | -$45,536 |
| | 2025 | 2021 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01ES028688 | Maternal organophosphate pesticide exposure, low birth weight and placental injury | 000 | 4 | NIH | 11/12/2024 | -$12,553 |
| | 2025 | 2021 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | RF1NS120947 | Establishing a Brain Health Index | 000 | 2 | NIH | 10/11/2024 | -$161,751 |
| | 2025 | 2020 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21NS118434 | Electrical impedance tomography for the improved assessment of pulmonary function in neuromuscular disease | 000 | 1 | NIH | 11/1/2024 | -$1,849 |
| | 2025 | 2020 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21CA251992 | Proteomic Characterization of Genomically Complex Sarcomas | 004 | 2 | NIH | 11/6/2024 | $0 |
| | 2025 | 2020 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21CA251992 | Proteomic Characterization of Genomically Complex Sarcomas | 003 | 2 | NIH | 11/5/2024 | -$386 |
| | 2025 | 2020 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21CA251992 | Proteomic Characterization of Genomically Complex Sarcomas | 002 | 2 | NIH | 11/5/2024 | $386 |
| | 2025 | 2018 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AG051658 | Advancing the Understanding of Postoperative Delirium Mechanisms via Multi-Omics | 000 | 3 | NIH | 10/1/2024 | -$4,928 |
|
| Issue Date FY: 2024 ( Subtotal = $124,504,906 ) (Continued on the next page) |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA258776 | Pan-Cancer characterization of 3’UTR somatic mutations controlling tumor immune evasion | 000 | 3 | NIH | 1/23/2024 | $512,353 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA276107 | Control of cancer cachexia via stimulation of resolution of inflammation | 000 | 1 | NIH | 12/27/2023 | $709,923 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA257672 | Detection of PD-1 inhibitory signaling and its molecular relays in T cells: Implications for cancer immunotherapy | 000 | 2 | NIH | 12/22/2023 | $640,414 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K23AT011043 | Understanding components of mind-body exercise for physical activity engagement in metabolic syndrome | 000 | 4 | NIH | 1/17/2024 | $162,680 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | U01CA263986 | Evaluation of Patient Factors and Sample Pre-Analytics on Predictive Multiplex Immunohistochemical Assays in Immuno-Oncology Patients | 003 | 3 | NIH | 4/17/2024 | $20,244 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01NS122589 | Neuronal Circuit Controlling Sleep-Promoting Ventrolateral Preoptic Neurons | 001 | 3 | NIH | 4/9/2024 | $26,242 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AT012166 | Mindful Steps: A Web-Based Mind-Body Exercise Intervention to Promote Physical Activity in Chronic Cardiopulmonary Disease | 001 | 2 | NIH | 6/28/2024 | $800,867 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL161012 | Leveraging omics data to understand sleep health and its consequences among diverse Hispanics/Latinos | 002 | 3 | NIH | 7/2/2024 | $576,765 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA238263 | The effects of PD-1 on tumor-mediated “emergency” myelopoiesis and fate commitment of myeloid cells: Implications for anti-tumor immunity | 002 | 5 | NIH | 9/6/2024 | $50,000 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01NS122589 | Neuronal Circuit Controlling Sleep-Promoting Ventrolateral Preoptic Neurons | 000 | 3 | NIH | 1/17/2024 | $337,389 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA238263 | The effects of PD-1 on tumor-mediated “emergency” myelopoiesis and fate commitment of myeloid cells: Implications for anti-tumor immunity | 000 | 5 | NIH | 1/24/2024 | $542,959 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL167383 | Thiol Isomerases and Oxidant Stress in Thrombus Formation | 001 | 1 | NIH | 6/28/2024 | $66,984 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K08DK131262 | Structure and mechanism of the kidney disease-causing protein APOL1 | 000 | 3 | NIH | 8/13/2024 | $164,484 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AA030770 | Cholesterol toxicity in alcohol-associated hepatitis | 000 | 2 | NIH | 5/24/2024 | $686,264 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL167383 | Thiol Isomerases and Oxidant Stress in Thrombus Formation | 000 | 1 | NIH | 5/15/2024 | $621,093 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA238263 | The effects of PD-1 on tumor-mediated “emergency” myelopoiesis and fate commitment of myeloid cells: Implications for anti-tumor immunity | 001 | 5 | NIH | 4/17/2024 | $30,168 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R00AG076739 | Cis proline directed proteotoxicity in the early development and therapy of traumatic brain injury and vascular dementia | 000 | 3 | NIH | 8/20/2024 | $248,895 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01DK096010 | AgRP neurons: circadian control and interactions with the HPA axis | 000 | 13 | NIH | 8/1/2024 | $485,384 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AG082093 | Non-coding RNAs in resilience to Alzheimer’s Disease | 002 | 2 | NIH | 6/28/2024 | $84,427 |
| | 2024 | 2024 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K01HL161034 | Admixture Mapping of Coronary Heart Disease and Associated Metabolomic Markers in African Americans | 000 | 2 | NIH | 1/29/2024 | $160,270 |
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