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 | Issue Date FY: 2025 ( Subtotal = $149,765,617 ) (Continued on the next page) |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA276107 | Control of cancer cachexia via stimulation of resolution of inflammation | 001 | 2 | NIH | 6/4/2025 | $69,170 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL167383 | Thiol Isomerases and Oxidant Stress in Thrombus Formation | 000 | 2 | NIH | 5/1/2025 | $602,867 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA276107 | Control of cancer cachexia via stimulation of resolution of inflammation | 000 | 2 | NIH | 11/25/2024 | $622,526 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21AG085089 | A lab-on-a-chip device for measuring multiple biochemical and biophysical biomarkers of Alzheimer’s disease | 000 | 2 | NIH | 4/1/2025 | $194,513 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R00EY032181 | Epigenomic mechanisms regulating RGC survival and axon regeneration | 000 | 5 | NIH | 1/16/2025 | $249,998 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA257672 | Detection of PD-1 inhibitory signaling and its molecular relays in T cells: Implications for cancer immunotherapy | 001 | 3 | NIH | 6/10/2025 | $70,941 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA257672 | Detection of PD-1 inhibitory signaling and its molecular relays in T cells: Implications for cancer immunotherapy | 000 | 3 | NIH | 12/18/2024 | $638,478 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R33DK131915 | Proteomic Biomarkers Prognostic for Diabetic Wound Healing | 001 | 4 | NIH | 8/4/2025 | $550,414 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21AG085089 | A lab-on-a-chip device for measuring multiple biochemical and biophysical biomarkers of Alzheimer’s disease | 001 | 2 | NIH | 4/28/2025 | $21,612 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL167383 | Thiol Isomerases and Oxidant Stress in Thrombus Formation | 001 | 2 | NIH | 9/15/2025 | $66,985 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL171121 | Novel Role Of ACTN4 in Sodium Reabsorption and Salt-Sensitive Hypertension | 001 | 2 | NIH | 8/26/2025 | $70,116 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL171121 | Novel Role Of ACTN4 in Sodium Reabsorption and Salt-Sensitive Hypertension | 000 | 2 | NIH | 11/20/2024 | $631,041 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K08AI168487 | Immunometabolic signatures of BCG-induced neonatal trained immunity | 000 | 3 | NIH | 6/30/2025 | $175,572 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R25AG088289 | Aging Research and Entrepreneurial Development Immersion | 000 | 2 | NIH | 9/5/2025 | $270,000 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01NS122589 | Neuronal Circuit Controlling Sleep-Promoting Ventrolateral Preoptic Neurons | 000 | 4 | NIH | 1/6/2025 | $337,669 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01DK130929 | Corticosteroids to Reduce Inflammation in Severe Pancreatitis (CRISP) | 001 | 4 | NIH | 6/16/2025 | $38,038 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01DK130929 | Corticosteroids to Reduce Inflammation in Severe Pancreatitis (CRISP) | 000 | 4 | NIH | 11/27/2024 | $342,342 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01DK142211 | New Treatment Strategies and Epigenetic Biomarker for Management of BPH | 000 | 2 | NIH | 8/13/2025 | $615,602 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA258776 | Pan-Cancer characterization of 3’UTR somatic mutations controlling tumor immune evasion | 001 | 4 | NIH | 6/2/2025 | $58,839 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA258776 | Pan-Cancer characterization of 3’UTR somatic mutations controlling tumor immune evasion | 000 | 4 | NIH | 1/22/2025 | $529,555 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21EY035436 | Multiplexed Sensing and Control of Neuromodulators and Peptides in the Awake Brain | 000 | 3 | NIH | 9/9/2025 | $216,125 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01CA272934 | WNT5a/ROR2-Mediated Hippo Pathway Activation in Prostate Cancer | 000 | 3 | NIH | 5/13/2025 | $395,509 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | P01AI177687 | Multi-Omics Analysis of Broadly Neutralizing Antibodies and Therapeutic Vaccination | 000 | 3 | NIH | 5/6/2025 | $1,505,858 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL169517 | Chronic Renal Insufficiency and Silent Progression of Aortic Stenosis (CRISP-AS) | 000 | 3 | NIH | 7/16/2025 | $763,572 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01NS128045 | Narrow Band Green Light Effects on Cortical Excitability and Responsivity in Migraine | 000 | 3 | NIH | 7/25/2025 | $563,186 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | DP1DK139958 | High-dimensional chemical targeting of multiple neuron types to regulate energy balance | 001 | 2 | NIH | 7/15/2025 | $800,000 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K23AG090744 | Development and Pilot Testing of an Electronic Health Record-based Serious Illness Communication Intervention for Older Adults in the Emergency Department | 000 | 1 | NIH | 9/9/2025 | $191,193 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AA032418 | Innate immune dysregulation in alcohol-associated liver disease | 000 | 1 | NIH | 9/12/2025 | $701,051 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01DK145097 | APOL1 Nephropathy: Linking Genetics and Mechanisms | 000 | 6 | NIH | 9/4/2025 | $659,358 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R35CA294015 | Navigating Pathways of Innate Immunity and Epigenetic Memory in Checkpoint Immunotherapy | 000 | 1 | NIH | 7/30/2025 | $846,982 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K08HD117001 | Placental NAD and its effect on labor onset | 000 | 1 | NIH | 7/21/2025 | $164,484 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01MD016068 | Effects of DASH Groceries on Blood Pressure in Black Residents of Urban Food Deserts | 002 | 4 | NIH | 8/9/2025 | $839,744 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01MH131586 | FastPlex: A Fast Deep Learning Segmentation Method for Accurate Choroid Plexus Morphometry | 000 | 3 | NIH | 3/12/2025 | $500,666 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R33AT012284 | Electrophysiological and ultrasound quantitative biomarkers for myofascial pain | 000 | 2 | NIH | 8/13/2025 | $2,313,780 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AI194935 | The Impact of the Bone Marrow Niche's Immune Privilege on Psoriatic Arthritis | 000 | 1 | NIH | 8/8/2025 | $3,406,145 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K01AA032055 | Role of Hepatokines in Alcohol-associated Liver Disease | 000 | 1 | NIH | 9/4/2025 | $177,736 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL173557 | Vascular-targeted Atheroprotective Gene therapies to Prevent Vein Graft Failure | 001 | 2 | NIH | 8/27/2025 | $75,390 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL173557 | Vascular-targeted Atheroprotective Gene therapies to Prevent Vein Graft Failure | 000 | 2 | NIH | 2/28/2025 | $678,507 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K23AT011043 | Understanding components of mind-body exercise for physical activity engagement in metabolic syndrome | 000 | 5 | NIH | 3/13/2025 | $163,109 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01LM014689 | HealthCoach: An LLM-driven chatbot to help patients gain actionable insights from their EHR notes and prepare for the next visit | 000 | 1 | NIH | 8/8/2025 | $400,627 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01HL180887 | Application of Modern Methods to Predict Risk and Estimate Treatment Effectiveness in Cardiogenic Shock | 000 | 1 | NIH | 8/20/2025 | $817,358 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21CA303219 | Determinants of PARP-inhibitor response in Breast Cancer Patients without germline mutations in BRCA1/2 | 000 | 1 | NIH | 7/15/2025 | $470,567 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | U24HL166784 | 2/2: PREcision VENTilation to attenuate Ventilation-Induced Lung Injury (PREVENT VILI) | 001 | 3 | NIH | 8/25/2025 | $685,256 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R21MH137740 | Hive Mind: Harnessing Collective Intelligence for Predicting Clinical High-Risk for Psychosis Outcomes | 000 | 1 | NIH | 3/20/2025 | $334,588 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R56NS144203 | Mechanisms of Cyanide-Induced Neurotoxicity and Purine Dysregulation | 000 | 1 | NIH | 7/23/2025 | $497,069 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K23ES035863 | Climate Variability and Respiratory Health in Asthma and COPD | 001 | 2 | NIH | 4/9/2025 | $0 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | K23ES035863 | Climate Variability and Respiratory Health in Asthma and COPD | 000 | 2 | NIH | 3/17/2025 | $256,202 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AG082093 | Non-coding RNAs in resilience to Alzheimer’s Disease | 000 | 3 | NIH | 3/6/2025 | $759,851 |
| | 2025 | 2025 | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 330 BROOKLINE AVE | BOSTON | MA | 02215-5400 | SUFFOLK | USA | R01AG082093 | Non-coding RNAs in resilience to Alzheimer’s Disease | 001 | 3 | NIH | 6/17/2025 | $67,543 |
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