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Promoting healthy weight across the pregnancy and postpartum period through dissemination of an evidence based intervention

Award Number: R01DK121475
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/01/2019
PERIOD OF PERFORMANCE END DATE: 03/31/2026

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Promoting healthy weight across the pregnancy and postpartum period through dissemination of an evidence based intervention - PROJECT SUMMARY The childbearing years are a particularly vulnerable time period for women during which they tend to gain disproportionately large amounts of weight when compared to men or other life periods. Weight gained during pregnancy and retained after the postpartum period contributes to obesity development and progression. Our team developed a lifestyle modification intervention in partnership with Parents as Teachers (PAT), a national home visiting, community based organization with significant reach in this population. PAT provides parent-child education and services free-of-charge to families through frequent home visits every year from the prenatal period until the child enters kindergarten. The intervention (EMPOWER) prevented excessive gestational weight gain and postpartum weight retention by embedding content within the existing PAT visit structure. This study will extend these findings with a pragmatic cluster randomized controlled trial to evaluate dissemination and implementation of EMPOWER across multiple levels (mother, parent educator, PAT site) to achieve widespread impact. We will evaluate the impact of EMPOWER on gestational weight gain and postpartum weight retention among mothers with overweight and obesity across the US (N= 266 EMPOWER; N= 266 usual care). Parent educators from 28 existing PAT sites (14 EMPOWER, 14 usual care) will receive the EMPOWER training curriculum through the PAT National Center using the existing training infrastructure. An extensive evaluation guided by RE-AIM, will determine implementation outcomes (acceptability, adoption, appropriateness, feasibility, fidelity, and adaptation). The Conceptual Framework for Implementation Research will characterize determinants that influence EMPOWER dissemination and implementation at multiple levels (mother, parent educator, PAT site) to enhance external validity (reach and maintenance) and population level impact. The findings from this innovative study will reach young women who have experienced the greatest increase in obesity prevalence in the past 45 years compared to other groups, due in part to weight gain associated with child bearing.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	5	6/11/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $570,537 )
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	5	3/21/2023	NON-COMPETING CONTINUATION	$570,537
														Subtotal = $570,537

Issue Date FY: 2022 ( Subtotal = $602,615 )
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	4	4/4/2022	NON-COMPETING CONTINUATION	$60,263
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	4	3/3/2022	NON-COMPETING CONTINUATION	$542,352
														Subtotal = $602,615

Issue Date FY: 2021 ( Subtotal = $654,057 )
2021	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	3	3/8/2021	NON-COMPETING CONTINUATION	$654,057
														Subtotal = $654,057

Issue Date FY: 2020 ( Subtotal = $619,951 )
2020	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	2	3/19/2020	NON-COMPETING CONTINUATION	$619,951
2020	2019	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	3/11/2020	NEW	$0
														Subtotal = $619,951

Issue Date FY: 2019 ( Subtotal = $681,014 )
2019	2019	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	5/24/2019	NEW	$681,014
														Subtotal = $681,014

Grand Total All Awards = $3,128,174

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Promoting healthy weight across the pregnancy and postpartum period through dissemination of an evidence based intervention

Award Number: R01DK121475

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/01/2019

PERIOD OF PERFORMANCE END DATE: 03/31/2026

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