Wednesday, May 25, 2022 5/25/2022

Examining community-based effectiveness of a substance use and HIV risk reduction intervention for young men of color

Award Number: R01DA041262
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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¿ DESCRIPTION (provided by applicant): Ethnic and racial minority young men who have sex with men (MYMSM) remain a critical population at the nexus of substance use and HIV/AIDS: a 132% increase in new infections concentrated among African American and Hispanic YMSM has been observed since 2002. The Young Men's Health Project (YMHP), a 4- session intervention utilizing motivational interviewing designed for HIV-negative or untested YMSM ages 18- 29 was found to be efficacious in significantly reducing substance use and condomless anal sex (CAS). To date, this is the first and only RCT of any published trial or CDC DEBI with YMSM to show significant reductions in both substance use and sexual risk. The CDC recently rated YMHP as "Best Evidence" and placed it on the compendium of Evidence Based Interventions and Best Practices for HIV Prevention. YMHP was tested through an efficacy trial in a research center environment with numerous inclusion and exclusion criteria, and thus, a community-based replication is the crucial next step in studying the intervention's effectiveness in the real world when delivered by staff to their clients. We will conduct a comparative effectiveness trial (CET) with two intensities of treatment offered following field-based HIV counseling and testing (C&T) - the YMHP intervention and enhanced "treatment as usual" (eTAU) HIV prevention services - in two real-world community based organizations (CBOs) to test their relative effectiveness in reducing substance use and CAS among HIV-negative MYMSM. The Specific Aims are to: 1) adapt the YMHP intervention for delivery in CBOs by peer counselors; 2) test the effectiveness of the YMHP intervention when delivered by peer counselors at two CBOs situated in high HIV incidence neighborhoods in New York City; and 3) assess the cost-effectiveness of YMHP relative to TAU. The proposed study will be implemented over two phases. In Phase 1 we will conduct qualitative research with staff at our collaborating agencies to adapt the efficacious YMHP intervention to the unique needs of MYMSM and incorporate existing systems and approaches utilized by site collaborators to facilitate for delivery by peer counselors. In Phase 2 we will randomize 260 HIV-negative substance using MYMSM into the YMHP intervention or eTAU. Assessments will include behavioral self-report measures, urine testing for substance use, and HIV and STI testing for sexual health outcomes. Working together with our CBO collaborators will help to address practical problems at the frontline of service provision to pave the way for a comprehensive program to reduce substance use and HIV infection among MYMSM. If effective, our program has the potential to exert a sustained and powerful influence on the effectiveness of behavioral interventions for economically disadvantaged, substance using MYMSM who are most at risk for HIV infection.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2022 ( Subtotal = -$30,959 )
2022	2019	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	695 PARK AVE	NEW YORK	NY	10065	NEW YORK	USA	Drug Abuse and Addiction Research Programs	000	4	11/15/2021	SUPPLEMENT FOR EXPANSION	-$30,959


Issue Date FY: 2019 ( Subtotal = $644,887 )
2019	2019	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	695 PARK AVE	NEW YORK	NY	10065	NEW YORK	USA	Drug Abuse and Addiction Research Programs	001	4	4/29/2019	SUPPLEMENT FOR EXPANSION	$72,319
2019	2019	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	695 PARK AVE	NEW YORK	NY	10065	NEW YORK	USA	Drug Abuse and Addiction Research Programs	000	4	4/26/2019	NON-COMPETING CONTINUATION	$572,568


Issue Date FY: 2018 ( Subtotal = $700,770 )
2018	2018	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	695 PARK AVE	NEW YORK	NY	10065	NEW YORK	USA	Drug Abuse and Addiction Research Programs	001	3	5/7/2018	SUPPLEMENT FOR EXPANSION	$75,809
2018	2018	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	695 PARK AVE	NEW YORK	NY	10065	NEW YORK	USA	Drug Abuse and Addiction Research Programs	000	3	5/4/2018	NON-COMPETING CONTINUATION	$624,961


Issue Date FY: 2017 ( Subtotal = $607,452 )
2017	2017	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	695 PARK AVE	NEW YORK	NY	10065	NEW YORK	USA	Drug Abuse and Addiction Research Programs	001	2	5/22/2017	NON-COMPETING CONTINUATION	$60,745
2017	2017	RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK	695 PARK AVE	NEW YORK	NY	10065	NEW YORK	USA	Drug Abuse and Addiction Research Programs	000	2	4/7/2017	NON-COMPETING CONTINUATION	$546,707


Issue Date FY: 2016 ( Subtotal = $689,286 )
2016	2016	CUNY, RESEARCH FOUNDATION	230 WEST 41ST STREET	NEW YORK	NY	10036	NEW YORK	USA	Drug Abuse and Addiction Research Programs	000	1	6/14/2016	NEW	$642,562
2016	2016	CUNY, RESEARCH FOUNDATION	230 WEST 41ST STREET	NEW YORK	NY	10036	NEW YORK	USA	Drug Abuse and Addiction Research Programs	001	1	6/17/2016	NEW	$46,724


Grand Total All Awards = $2,611,436

Sum of Action Amount is $2,611,436;

Grand Total = $2,611,436

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Examining community-based effectiveness of a substance use and HIV risk reduction intervention for young men of color

Award Number: R01DA041262

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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