Thursday, November 21, 2024 11/21/2024

CARES-REACH (Colorectal Cancer Awareness, Research, Education and Screening-Rural Expansion, Access and Capacity for Health)

Award Number: R01CA249689
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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ABSTRACT Despite the Healthy People 2020 goal of 70.5%, colorectal cancer (CRC) screening rates in Federally Qualified Health Centers (FQHCs) are about 40%. The proposed study seeks to address this disparity and accelerate the adoption of effective cancer prevention and control screening practices to promote CRC screening. Leveraging our established community-academic network, which emphasizes participatory approaches among community, clinical, and academic stakeholders, we build on our extensive preparatory research that tested a low-literacy educational intervention plus Fecal Immunochemical Test [FIT]), and which resulted in initial screening rates of 80%. This work was primarily carried-out in urban-based settings. Prior research shows that repeat FIT screening rates often drop significantly without intervention and that there are notable geographic- related CRC disparities with higher mortality seen among individuals in rural areas. Additional research is needed to address repeat screening and expand our reach to other at-risk and rural populations. Informed by a community-based participatory research (CBPR) framework and enriched by implementation science approaches, CARES-REACH features a stepped wedge design with extension for maintenance to support an implementation strategy focused on multiple levels: organizational, provider, and patient level that entail processes to boost initial and repeat screening among average risk and age-eligible adults. This multilevel study entails implementation of a core set of evidence-based interventions (EBIs) that include: low literacy patient education (English, Spanish, and Haitian Creole language); provider education, system-wide electronic medical record (EMR) tools and prompts, and FIT distribution plus an organization-wide cancer control champion who motivates providers, navigates patients, and monitors system-wide screening activities. Specific aims are to: 1) implement an organization-wide multilevel CRC intervention using EBIs plus a cancer control champion in FQHCs located in rural and urban Central and Southwest Florida; 2) explore whether practice setting and population characteristics may differentially impact annual clinic CRC uniform Data system (UDS) screening rates; and 3) conduct a comprehensive evaluation of the implementation process (facilitators and impediments), resource requirements, and intermediate patient outcomes for the program in FQHC organizations. The intervention will be rolled out in a stepwise-method across clinics: one group of clinics receives early intervention roll-out and the other clinics are delayed to allow for rigorous comparison. The main outcome is change in annual clinic CRC screening rates compared to CRC screening rates of the prior year for each clinic as well as comparing screening rates among early roll-out clinics vs. delayed roll-out clinics. Addressing implementation processes will guide and direct scale-up to other FQHCs and community health systems.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $600,913 )
2024	2024	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 USF MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	001	5	4/18/2024	NON-COMPETING CONTINUATION	$31,626
2024	2024	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 USF MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	5	2/19/2024	NON-COMPETING CONTINUATION	$569,287
														Subtotal = $600,913

Issue Date FY: 2023 ( Subtotal = $777,286 )
2023	2023	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	4	2/28/2023	NON-COMPETING CONTINUATION	$609,630
2023	2023	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	002	4	3/2/2023	SUPPLEMENT FOR EXPANSION	$87,724
2023	2023	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	001	4	3/1/2023	SUPPLEMENT FOR EXPANSION	$79,932
														Subtotal = $777,286

Issue Date FY: 2022 ( Subtotal = $889,515 )
2022	2022	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	003	3	4/1/2022	SUPPLEMENT FOR EXPANSION	$207,977
2022	2022	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	004	3	9/9/2022	SUPPLEMENT FOR EXPANSION	$68,055
2022	2022	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	002	3	3/31/2022	NON-COMPETING CONTINUATION	$613,483
2022	2021	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	2	10/20/2021	SUPPLEMENT FOR EXPANSION	$0
2022	2021	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	001	2	10/21/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $889,515

Issue Date FY: 2021 ( Subtotal = $748,627 )
2021	2021	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	2	3/9/2021	NON-COMPETING CONTINUATION	$617,969
2021	2021	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	001	2	9/20/2021	SUPPLEMENT FOR EXPANSION	$130,658
														Subtotal = $748,627

Issue Date FY: 2020 ( Subtotal = $646,731 )
2020	2020	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	1	3/30/2020	NEW	$646,731
														Subtotal = $646,731

Grand Total All Awards = $3,663,072

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CARES-REACH (Colorectal Cancer Awareness, Research, Education and Screening-Rural Expansion, Access and Capacity for Health)

Award Number: R01CA249689

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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