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 | Issue Date FY: 2025 ( Subtotal = $14,550,290 ) (Continued on the next page) |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM133482 | Illuminating Notch receptor-ligand selectivity through structure-guided protein engineering | 000 | 6 | NIH | 1/16/2025 | $463,375 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R03CA280404 | Investigating lipid phenotype as a metabolic adaptation to microenvironmental stress | 000 | 2 | NIH | 2/14/2025 | $84,250 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA278300 | The impact of inflammation on HSPC composition and disease progression in chronic myelomonocytic leukemia | 000 | 3 | NIH | 2/14/2025 | $469,813 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA299899 | Structure-function studies of LAG3 interactions with antibodies and cellular ligands | 000 | 1 | NIH | 3/24/2025 | $549,962 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA255265 | Efficacy of a Mindfulness-Based Stress Management Program for Allogeneic HCT Caregivers | 000 | 5 | NIH | 3/4/2025 | $488,935 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA258089 | Eco-evolutionary drivers of clonal dynamics during UV-induced skin carcinogenesis (PQ3) | 000 | 5 | NIH | 3/4/2025 | $576,018 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R21CA288927 | Development of bifunctional CDK2 inhibitors for treatment of CCNE1-driven cancers | 000 | 2 | NIH | 3/3/2025 | $177,242 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM143004 | Biophysical basis for enzyme mediated deglycation in protein repair | 000 | 5 | NIH | 3/21/2025 | $370,575 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM142577 | New reagents for C-C and C-N bond formation | 000 | 5 | NIH | 4/16/2025 | $411,750 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM133482 | Illuminating Notch receptor-ligand selectivity through structure-guided protein engineering | 003 | 6 | NIH | 3/6/2025 | $3,083 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM133482 | Illuminating Notch receptor-ligand selectivity through structure-guided protein engineering | 003 | 6 | NIH | 3/6/2025 | $58,549 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | P30CA076292 | Moffitt Cancer Center Support Grant | 001 | 27 | NIH | 3/5/2025 | $3,649,340 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA283730 | Defining impact of in situ activation of CD40 and type 1 interferon signaling on theTME and systemic T cell immunity in murine models and cancer patients | 000 | 2 | NIH | 4/10/2025 | $414,184 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA259387 | Mathematical Model-Guided Adoptive Immunotherapy in Bladder Cancer | 000 | 5 | NIH | 3/13/2025 | $428,435 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R34CA297368 | Libre Del Cigarrillo: Development of an mHealth Smoking Cessation App to Extend Reach of a Validated Smoking Cessation Intervention for Spanish-speaking Smokers | 000 | 1 | NIH | 4/1/2025 | $316,873 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA259046 | Chromosome 1q ceRNAs in Melanoma Progression and Metastasis | 000 | 5 | NIH | 3/20/2025 | $375,244 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA279713 | RBFOX2 deregulation promotes pancreatic cancer progression through alternative splicing | 000 | 3 | NIH | 3/20/2025 | $414,990 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA276496 | Body composition and adiposity-associated thromboinflammation in colorectal cancer prognosis | 000 | 2 | NIH | 3/20/2025 | $598,180 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R03CA286682 | Targeting ULK3 for the treatment of triple negative breast cancer | 000 | 2 | NIH | 11/14/2024 | $84,250 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R21CA286417 | Development of adverse event (AE) derived biomarkers for predicting clinical outcomes in lung cancer | 000 | 2 | NIH | 12/16/2024 | $212,689 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA290007 | An integrated mathematical modeling approach to define how the aging bone ecosystem drives multiple myeloma evolution and treatment response | 000 | 1 | NIH | 12/16/2024 | $620,521 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA269721 | Role of ULK3 in Sensitive and Refractory Multiple Myeloma | 000 | 3 | NIH | 11/15/2024 | $480,943 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA275974 | Methylomic basis of survival disparities among Black and White women with high-grade serous ovarian cancer | 000 | 3 | NIH | 12/18/2024 | $536,745 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA289581 | Release of interleukin-1a as a mediator of immune evasion in cancer | 000 | 1 | NIH | 12/10/2024 | $568,538 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA260356 | Anti-tumor potential of temperature-sensitive p53 mutants | 000 | 5 | NIH | 2/13/2025 | $400,132 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA279378 | Selective targeting of TAF1 function in acute myeloid leukemia | 000 | 2 | NIH | 1/14/2025 | $572,062 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA289387 | Remodeling the Immune Landscape in Breast Cancer Leptomeningeal Disease Using Dendritic Cell Therapy is an Effective Treatment and Protects Against Disease Recurrence. | 000 | 1 | NIH | 12/12/2024 | $657,121 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA141244 | Allosteric Regulation of MDMX by Protein Disorder | 000 | 14 | NIH | 12/11/2024 | $304,497 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA299480 | The MIND-BC Study: MIND diet for Breast cancer Cognition | 000 | 1 | NIH | 3/7/2025 | $713,235 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01NS135220 | Targeting Malignant Reprogramming of Glioblastoma Stem Cells Through Dual Inhibition of S6K1 and BIRC3 | 000 | 2 | NIH | 12/12/2024 | $541,074 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | DP2AG077698 | AGING AS A SELECTIVE PRESSURE THAT DRIVES TUMOR PROGRESSION | 001 | 2 | NIH | 2/20/2025 | $421,201 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R21CA267283 | Developing GRB2-PROTACs for Treatment of Lung Cancer | 000 | 2 | NIH | 4/14/2025 | -$4,680 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R37CA234021 | Developing and credentialing patient-derived xenograft models to advance therapeutic approaches for chronic myelomonocytic leukemia | 001 | 6 | NIH | 3/14/2025 | $124,541 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | UG1HL108987 | Blood and Marrow Transplant Clinical Trials Network (BMT CTN) - Core Clinical Centers - UG1 | 001 | 14 | NIH | 4/2/2025 | $112,888 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | T32CA090314 | Behavioral Oncology Education & Career Development | 002 | 21 | NIH | 3/19/2025 | $413,840 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | K99CA271040 | Mindfulness-based ecological momentary intervention for smoking cessation among cancer survivors | 000 | 2 | NIH | 1/9/2025 | $0 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R37CA229810 | Using Radiogenomics to Noninvasively Predict the Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Uncover Hidden Biology | 001 | 6 | NIH | 2/12/2025 | $296,143 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA231952 | Partnering with a State Food Bank to Provide Tobacco Treatment to Underserved Smokers | 000 | 6 | NIH | 12/6/2024 | $0 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | D43CA260649 | Ghana IntegRative Approach to Cancer ResEarch Training: The Grace Program | 000 | 4 | NIH | 12/11/2024 | $0 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R34CA289918 | Adaptation and Preliminary Evaluation of Energize-MBC: Cognitive Behavioral Therapy for Fatigue among Women with Metastatic Breast Cancer | 000 | 1 | NIH | 12/6/2024 | $0 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA291735 | A hybrid effectiveness-implementation trial to integrate precision skin cancer risk feedback in federally qualified health centers | 000 | 1 | NIH | 10/17/2024 | $0 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM133482 | Illuminating Notch receptor-ligand selectivity through structure-guided protein engineering | 002 | 5 | NIH | 3/6/2025 | -$3,083 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R21CA267141 | Defining and targeting the epigenetic programs involved in melanoma development | 000 | 2 | NIH | 4/11/2025 | -$523 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM133482 | Illuminating Notch receptor-ligand selectivity through structure-guided protein engineering | 001 | 5 | NIH | 3/6/2025 | -$58,549 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA227073 | Development of New Casein Kinase 1 Inhibitor for the Treatment of Brain Cancers | 000 | 6 | NIH | 4/4/2025 | -$3,910 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R03CA259873 | A framework to integrate live-cell imaging with single-cell sequencing and learn how cells adapt to new environments | 000 | 2 | NIH | 4/4/2025 | -$58 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA279065 | Spatial and Bayesian modeling methods for assessment of the tumor immune microenvironment and survival of women with ovarian cancer | 000 | 1 | NIH | 2/20/2025 | -$88,194 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01NS131912 | Metabolic and molecular regulation of myeloid cell functions in brain cancer | 000 | 1 | NIH | 2/20/2025 | -$38,505 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R37CA234021 | Developing and credentialing patient-derived xenograft models to advance therapeutic approaches for chronic myelomonocytic leukemia | 000 | 5 | NIH | 3/14/2025 | -$124,541 |
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