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 | Issue Date FY: 2025 ( Subtotal = $4,514,403 ) |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA141244 | Allosteric Regulation of MDMX by Protein Disorder | 000 | 14 | NIH | 12/11/2024 | $304,497 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM133482 | Illuminating Notch receptor-ligand selectivity through structure-guided protein engineering | 000 | 6 | NIH | 1/16/2025 | $463,375 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R03CA286682 | Targeting ULK3 for the treatment of triple negative breast cancer | 000 | 2 | NIH | 11/14/2024 | $84,250 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA269721 | Role of ULK3 in Sensitive and Refractory Multiple Myeloma | 000 | 3 | NIH | 11/15/2024 | $480,943 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01NS135220 | Targeting Malignant Reprogramming of Glioblastoma Stem Cells Through Dual Inhibition of S6K1 and BIRC3 | 000 | 2 | NIH | 12/12/2024 | $541,074 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA279378 | Selective targeting of TAF1 function in acute myeloid leukemia | 000 | 2 | NIH | 1/14/2025 | $572,062 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA289581 | Release of interleukin-1a as a mediator of immune evasion in cancer | 000 | 1 | NIH | 12/10/2024 | $568,538 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA289387 | Remodeling the Immune Landscape in Breast Cancer Leptomeningeal Disease Using Dendritic Cell Therapy is an Effective Treatment and Protects Against Disease Recurrence. | 000 | 1 | NIH | 12/12/2024 | $657,121 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA275974 | Methylomic basis of survival disparities among Black and White women with high-grade serous ovarian cancer | 000 | 3 | NIH | 12/18/2024 | $536,745 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA290007 | An integrated mathematical modeling approach to define how the aging bone ecosystem drives multiple myeloma evolution and treatment response | 000 | 1 | NIH | 12/16/2024 | $620,521 |
| | 2025 | 2025 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R21CA286417 | Development of adverse event (AE) derived biomarkers for predicting clinical outcomes in lung cancer | 000 | 2 | NIH | 12/16/2024 | $212,689 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | K99CA271040 | Mindfulness-based ecological momentary intervention for smoking cessation among cancer survivors | 000 | 2 | NIH | 1/9/2025 | $0 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | D43CA260649 | Ghana IntegRative Approach to Cancer ResEarch Training: The Grace Program | 000 | 4 | NIH | 12/11/2024 | $0 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R34CA289918 | Adaptation and Preliminary Evaluation of Energize-MBC: Cognitive Behavioral Therapy for Fatigue among Women with Metastatic Breast Cancer | 000 | 1 | NIH | 12/6/2024 | $0 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA231952 | Partnering with a State Food Bank to Provide Tobacco Treatment to Underserved Smokers | 000 | 6 | NIH | 12/6/2024 | $0 |
| | 2025 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA291735 | A hybrid effectiveness-implementation trial to integrate precision skin cancer risk feedback in federally qualified health centers | 000 | 1 | NIH | 10/17/2024 | $0 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R03CA270475 | The COACH Study: A Framework for individualized COaching in young Adult Cancer survivors to encourage Healthy behaviors | 000 | 2 | NIH | 10/9/2024 | $0 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | U54CA163068 | 2/2 Ponce Health Sciences University-Moffitt Cancer Center Partnership | 001 | 11 | NIH | 10/8/2024 | $227,289 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | K08CA231454 | Finding Synergy with Radiation Therapy and Immunotherapy for Patients with Lung Cancer | 000 | 5 | NIH | 11/21/2024 | $0 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | K08CA231454 | Finding Synergy with Radiation Therapy and Immunotherapy for Patients with Lung Cancer | 002 | 5 | NIH | 12/2/2024 | -$238,752 |
| | 2025 | 2023 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA233512 | Functional reprogramming of tumor-MDSC through antibody-based therapies targeting Notch ligands | 000 | 5 | NIH | 10/11/2024 | -$84,205 |
| | 2025 | 2022 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | UH3CA202970 | Validation of EGFR Protein Complexes as Molecular Diagnostics | 000 | 5 | NIH | 10/21/2024 | -$32,500 |
| | 2025 | 2022 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | U54CA163068 | 2/2 Ponce Health Sciences University-Moffitt Cancer Center Partnership | 000 | 10 | NIH | 10/8/2024 | -$227,289 |
| | 2025 | 2022 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R21CA263911 | Developing mathematical model driven optimized recurrent glioblastoma therapies | 000 | 2 | NIH | 11/6/2024 | $0 |
| | 2025 | 2022 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | K08CA231454 | Finding Synergy with Radiation Therapy and Immunotherapy for Patients with Lung Cancer | 001 | 4 | NIH | 12/2/2024 | -$107,851 |
| | 2025 | 2022 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R21CA264635 | Exploiting Epigenetic Vulnerabilities In Glioblastoma Stem Cells Through Reprogramming | 000 | 1 | NIH | 1/8/2025 | -$15,789 |
| | 2025 | 2021 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | P30CA076292 | P30 Administrative Supplement to Cancer Center Support Grant to Strengthen NCI-Supported Community Outreach Capacity through Community Health Educators of the National Outreach Network. | 000 | 23 | NIH | 10/1/2024 | -$14,698 |
| | 2025 | 2021 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA212169 | Augmenting T cell trafficking and functionality through novel combinations of epigenetic agents and PD-1 blockade | 000 | 5 | NIH | 12/3/2024 | -$33,617 |
|
| Issue Date FY: 2024 ( Subtotal = $51,493,908 ) (Continued on the next page) |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA266803 | An Ionizing Radiation Acoustics Imaging (iRAI) Approach for guided Flash Radiotherapy | 000 | 3 | NIH | 8/28/2024 | $644,134 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R03AI175796 | The role of HPV E1 in regulating the NRF2-KEAP1 pathway | 001 | 2 | NIH | 5/10/2024 | $8,425 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R03AI175796 | The role of HPV E1 in regulating the NRF2-KEAP1 pathway | 000 | 2 | NIH | 11/20/2023 | $75,825 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA262483 | Defining and targeting epigenetic plasticity-driven drug resistance and immune escape in melanoma | 000 | 3 | NIH | 7/9/2024 | $463,483 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01NS117926 | Elucidating the epigenetic landscape of neurofibromatosis and development of therapeutic targets | 000 | 4 | NIH | 8/20/2024 | $395,445 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA272601 | Modeling the role and regulation of reactive stroma in breast ductal carcinoma microinvasions | 000 | 3 | NIH | 8/15/2024 | $551,254 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM143004 | Biophysical basis for enzyme mediated deglycation in protein repair | 001 | 4 | NIH | 7/31/2024 | $41,175 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R35GM143004 | Biophysical basis for enzyme mediated deglycation in protein repair | 000 | 4 | NIH | 2/27/2024 | $370,575 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | K22CA262352 | Tele-resistance training during chemotherapy for advanced upper gastrointestinal cancer | 000 | 3 | NIH | 2/14/2024 | $161,973 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA255398 | Characterizing oncogenic function of ITCH in melanoma | 000 | 4 | NIH | 9/10/2024 | $18,839 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA268973 | HIV Genomic Aging Project in Oncology (HIV-GAP) | 000 | 4 | NIH | 8/2/2024 | $761,817 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA249016 | Radiomics and Pathomics to predict upstaging of DCIS | 000 | 4 | NIH | 7/2/2024 | $648,573 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | DP2AG077698 | AGING AS A SELECTIVE PRESSURE THAT DRIVES TUMOR PROGRESSION | 000 | 2 | NIH | 8/9/2024 | $990,450 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA256193 | Characterization and targeting of the epigenetic state underlying uveal melanoma liver metastasis | 000 | 4 | NIH | 8/16/2024 | $618,592 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA258089 | Eco-evolutionary drivers of clonal dynamics during UV-induced skin carcinogenesis (PQ3) | 001 | 4 | NIH | 4/17/2024 | $32,002 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA258089 | Eco-evolutionary drivers of clonal dynamics during UV-induced skin carcinogenesis (PQ3) | 000 | 4 | NIH | 3/6/2024 | $576,018 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA262121 | Bile acids restrict functional reprogramming of myeloid-derived suppressor cells in tumor beds | 000 | 4 | NIH | 7/25/2024 | $357,915 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA260356 | Anti-tumor potential of temperature-sensitive p53 mutants | 001 | 4 | NIH | 4/17/2024 | $22,230 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01CA260356 | Anti-tumor potential of temperature-sensitive p53 mutants | 000 | 4 | NIH | 2/9/2024 | $400,130 |
| | 2024 | 2024 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | 12902 USF MAGNOLIA DR | TAMPA | FL | 33612-9416 | HILLSBOROUGH | USA | R01GM140140 | Direct Control of the human CMG Helicase by Myc and Rb | 000 | 4 | NIH | 5/15/2024 | $329,400 |
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