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Identifying and Reducing Disparities in Patient-Reported Outcomes Among African American Prostate Cancer Survivors

Award Number: R01CA242742
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/23/2020
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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Identifying and Reducing Disparities in Patient-Reported Outcomes Among African American Prostate Cancer Survivors - PROJECT SUMMARY/ABSTRACT We propose a project to reduce morbidity as related to health disparities in prostate cancer survivors by identifying disparities in symptom burden and their contributors among African American prostate cancer survivors. The limited research reported that patient-reported quality of life outcomes are worse in African American compared to White prostate cancer survivors. Most importantly, other critically important symptom burden outcomes are largely understudied and overlooked in minorities. Previous research suggests African American prostate cancer survivors likely experience signiﬁcant symptom burden for outcomes that are avoidable or treatable. The proposed project will address these critical public health concerns in the growing population of African American prostate cancer survivors.! This project aims to 1) Compare symptom burden between African American and White prostate cancer survivors, 2) Identify multilevel modiﬁable risk factors for worse symptom burden among both African American and White prostate cancer survivors, such as cultural, health behavior-related, psychosocial, and racial discrimination factors, and 3) Identify multilevel non-modiﬁable risk factors for worse symptom burden, such as genetic, clinical, treatment-related, and demographic factors. The risk factors we will study are informed by an adapted multilevel contextual model examining the levels of the person, social environment, and healthcare system.! This will be among the ﬁrst and most comprehensive studies we are aware of to compare symptom burden between African American and White prostate cancer survivors. It will be the ﬁrst we are aware of to identify modiﬁable and non-modiﬁable risk factors for worse symptom burden. These risk factor data will allow us to develop targeted interventions and identify high-risk individuals for monitoring and early intervention. In summary, this project's focus on identifying disparities and their risk factors supports the Healthy People 2020 goals of eliminating health disparities and improving quality of life in cancer survivors.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2027 ( Subtotal = -$46,446 )
2027	2024	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 USF MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	5	10/30/2026	NON-COMPETING CONTINUATION	-$46,446
														Subtotal = -$46,446

Issue Date FY: 2024 ( Subtotal = $356,298 )
2024	2024	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 USF MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	5	5/29/2024	NON-COMPETING CONTINUATION	$356,298
														Subtotal = $356,298

Issue Date FY: 2023 ( Subtotal = $694,788 )
2023	2023	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	3	4/7/2023	SUPPLEMENT FOR EXPANSION	$327,239
2023	2023	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	001	4	7/10/2023	NON-COMPETING CONTINUATION	$367,549
														Subtotal = $694,788

Issue Date FY: 2022 ( Subtotal = $375,050 )
2022	2022	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	3	7/12/2022	NON-COMPETING CONTINUATION	$375,050
														Subtotal = $375,050

Issue Date FY: 2021 ( Subtotal = $380,399 )
2021	2021	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	2	6/4/2021	NON-COMPETING CONTINUATION	$380,399
														Subtotal = $380,399

Issue Date FY: 2020 ( Subtotal = $385,876 )
2020	2020	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.	12902 MAGNOLIA DR	TAMPA	FL	33612	HILLSBOROUGH	USA	Cancer Cause and Prevention Research	000	1	7/23/2020	NEW	$385,876
														Subtotal = $385,876

Grand Total All Awards = $2,145,965

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Identifying and Reducing Disparities in Patient-Reported Outcomes Among African American Prostate Cancer Survivors

Award Number: R01CA242742

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/23/2020

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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