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Social Determinants and Timeliness of Total Knee Replacement: A National Perspective

Award Number: R01AR078342
ORGANIZATION: NATIONAL INSTITUTE OF ARTHRITIS & MUSCULOSKELETAL & SKIN DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary The proposed R01 aims to augment data from the FORCE-TJR national Registry with radiographic readings, geospatial information and Medicare claims data to quantify timeliness of total knee replacement (TKR), and investigate the social determinants (SD) affecting timing of TKR. We propose 3 specific aims. Aim 1 applies validated appropriateness criteria to a representative sample of the FORCE-TJR registry patients to classify them as either premature or appropriate but with 5 different levels of functional disability. Aim 2 appends this sample with geospatial information (SD) about their environment and determine the effect of the SD factors on TKR utilization. Aim 3 determine the effect of the SD factors on improvement after surgery. We examine the effect of SD factors related to (1) the medical care environment (i.e., access to and practice patterns of medical care) and (2) the built environment (i.e., all of the physical parts of where we live and work (e.g., homes, buildings, streets, open spaces, and infrastructure)). Our project will be the first to examine timing of TKR at a national level, and will provide new knowledge regarding the association of the medical care and built environments with timeliness of TKR utilization. Our findings will also inform clinical and public policy interventions aimed at targeting TKR to those who would benefit most from the procedure, and add to evidence that would support the proposition that improvements to the environment could lead to an overall reduction in disability pertaining to knee osteoarthritis.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $418,946 )
2025	2025	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Arthritis, Musculoskeletal and Skin Diseases Research	001	4	12/31/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$418,946
2025	2024	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	3	12/30/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $418,946

Issue Date FY: 2024 ( Subtotal = $416,302 )
2024	2024	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	3	11/14/2023	NON-COMPETING CONTINUATION	$386,258
2024	2024	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Arthritis, Musculoskeletal and Skin Diseases Research	001	3	6/21/2024	NON-COMPETING CONTINUATION	$30,044
														Subtotal = $416,302

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	2	2/2/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $726,577 )
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	2	2/7/2022	NON-COMPETING CONTINUATION	$660,523
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Arthritis, Musculoskeletal and Skin Diseases Research	001	2	5/4/2022	NON-COMPETING CONTINUATION	$66,054
														Subtotal = $726,577

Issue Date FY: 2021 ( Subtotal = $721,641 )
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Arthritis, Musculoskeletal and Skin Diseases Research	000	1	3/18/2021	NEW	$721,641
														Subtotal = $721,641

Grand Total All Awards = $2,283,466

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Social Determinants and Timeliness of Total Knee Replacement: A National Perspective

Award Number: R01AR078342

ORGANIZATION: NATIONAL INSTITUTE OF ARTHRITIS & MUSCULOSKELETAL & SKIN DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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