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Developing a Malaria Intelligence System and Mobile Decision-Support App to Enhance Malaria Prevention and Control in Kenya

Award Number: R01AI198742
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/20/2026
PERIOD OF PERFORMANCE END DATE: 07/31/2031

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Developing a Malaria Intelligence System and Mobile Decision-Support App to Enhance Malaria Prevention and Control in Kenya - Developing a Malaria Intelligence System and Mobile Decision-Support App to Enhance Malaria Prevention and Control in Kenya Project Summary Over the past decade, the massive scale-up of long-lasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS) in Africa has led to significant reductions in malaria mortality and morbidity. However, the extensive use of pyrethroid insecticides has resulted in the emergence of insecticide- resistant mosquito populations. In parallel, high coverage of LLINs and IRS has led to increased outdoor biting behavior and resting behavior. These changes in vector ecology and behavior have significantly limited the effectiveness of current first-line interventions that target indoor biting and resting mosquitoes. Additionally, these ecological and behavioral changes in vectors have made malaria transmission more heterogeneous, with significant local variations in vector ecology, malaria risk, and the effectiveness of control methods. As a result, uniform, one-size-fits-all strategies are insufficient. To achieve greater impact, malaria control efforts must be adaptive and tailored to specific regional conditions. Despite advances in computing tools and model techniques, significant gaps remain in the development of accurate malaria risk forecasting models and responsive, location-specific malaria control strategies. The increasing availability of high-resolution satellite data, improved access to vector and disease incidence data, and advancements in data analytics now offer new opportunities for data- driven decision-making. The central objective of this application is to develop a mobile health system that comprises the Malaria Intelligence System and a Mobile Decision-Support App, which will enable the design and implementation of locally tailored malaria control strategies in Kenya. This objective will be pursued through three specific aims: 1) Develop a Malaria Intelligence System to automatedly retrieve and integrate environmental, entomological, and disease incidence data from public sources; 2) Build a Mobile Decision-Support App to support the development of region- specific, precision malaria control strategies; and 3) Evaluate and refine the mobile health system to inform system scale-up and broader implementation. Completion of this project will: 1) Improve malaria outbreak forecasting by integrating diverse environmental and epidemiological datasets using AI-based methods; 2) Provide decision-makers with real-time environmental and weather data and a dynamic analyses of malaria risk and transmission patterns; and 3) Develop a mobile health system to facilitate the implementation of effective, geographically targeted malaria interventions. The findings from this project will inform and strengthen malaria control strategies not only in Kenya but also in other malaria-endemic countries across Africa.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $667,643 )
2026	2026	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	Allergy and Infectious Diseases Research	000	1	8/20/2026	NEW	$667,643
														Subtotal = $667,643

Grand Total All Awards = $667,643

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Developing a Malaria Intelligence System and Mobile Decision-Support App to Enhance Malaria Prevention and Control in Kenya

Award Number: R01AI198742

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/20/2026

PERIOD OF PERFORMANCE END DATE: 07/31/2031

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