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Informatics-enhanced Social Networks and Affiliation Processes (ISNAP) to promote risk reduction and early diagnosis of Alzheimer's and Related Dementias.

Award Number: R01AG089193
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2024
PERIOD OF PERFORMANCE END DATE: 06/30/2029

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Informatics-enhanced Social Networks and Affiliation Processes (ISNAP) to promote risk reduction and early diagnosis of Alzheimer's and Related Dementias. - Modification of risky health behaviors to improve brain health and early detection of the disease are pivotal components to alleviate the burden of Alzheimer’s Disease and Related Dementias (ADRD). Both these components are shaped by individuals’ inter-personal and intra-personal ties. In the proposed research, we will seek to develop a methodological framework that enables us to (a) examine individual- and group-level dynamics associated with information-seeking and care-seeking behaviors in online and offline contexts for risk reduction and early detection of ADRD, and (b) model population-level dyadic characteristics and their relationship with individuals’ behavioral state/stage, and manifestation of sociobehavioral processes. Grounded in theories of human behavior, cognitive psychology, and network sciences, we will employ mixed-methods approach to analyze behavior dynamics related to ADRD risk reduction and early detection. Specifically, we will employ theories (e.g., Integrated Behavioral Model, Transtheoretical Model of Change, Care seeking delay model) and methods that facilitate granular (e.g., grounded theory analysis), high-throughput (e.g., natural language processing, deep learning), and collective (e.g., ego-centered networks, affiliation networks) modeling of information seeking and care seeking behaviors. While generally applicable, our methods will be developed to address risk factors associated with cognitive aging, ADRD risk reduction, and early detection. This research proposal will result in 1) novel methods to incorporate behavioral/care seeking stages and processes into network models of ADRD risk behavior dynamics and 2) new proposals for the development of multilevel interventions to support individuals engaging in modification of risky health behaviors and care seeking behaviors within and beyond ADRD domain.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $638,047 )
2026	2026	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON	7000 FANNIN ST FL 9	HOUSTON	TX	77030	HARRIS	USA	Aging Research	000	3	6/11/2026	NON-COMPETING CONTINUATION	$638,047
														Subtotal = $638,047

Issue Date FY: 2025 ( Subtotal = $647,873 )
2025	2025	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON	7000 FANNIN ST FL 9	HOUSTON	TX	77030	HARRIS	USA	Aging Research	001	2	8/4/2025	NON-COMPETING CONTINUATION	$647,873
2025	2024	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON	7000 FANNIN ST FL 9	HOUSTON	TX	77030	HARRIS	USA	Aging Research	000	1	5/16/2025	NEW	$0
														Subtotal = $647,873

Issue Date FY: 2024 ( Subtotal = $691,130 )
2024	2024	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON	7000 FANNIN ST FL 9	HOUSTON	TX	77030	HARRIS	USA	Aging Research	000	1	9/20/2024	NEW	$691,130
														Subtotal = $691,130

Grand Total All Awards = $1,977,050

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Informatics-enhanced Social Networks and Affiliation Processes (ISNAP) to promote risk reduction and early diagnosis of Alzheimer's and Related Dementias.

Award Number: R01AG089193

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2024

PERIOD OF PERFORMANCE END DATE: 06/30/2029

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