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NATIONAL STEM CELL RESOURCE

Award Number: P40RR015452
ORGANIZATION: NATIONAL CENTER FOR RESEARCH RESOURCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2000
PERIOD OF PERFORMANCE END DATE: 08/31/2005

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NATIONAL STEM CELL RESOURCE - Embryonal stem (ES) cells and lineage- or tissue-specific stem cells are important models in biomedical studies, but the availability and accessibility of research materials in this rapidly advancing field often become limiting. These restrictions can be addressed by a central, internationally recognized Stem Cell Resource devoted to acquisition and distribution of cells, reagents and information on nonhuman ES cells and postnatally derived stem cells from a variety of species. ATCC is the oldest, largest and most experienced organization engaging in this type of endeavor. Mechanisms for efficient and cost-effective accessioning, characterization, expansion, preservation and distribution of biomaterials and information are firmly in place and highly utilized daily. To a large degree these procedures were developed at ATCC out of necessity, providing an atmosphere fostering continued experimentation and improvement. In addition, several ATCC scientists are pursuing research relevant to stem cell biology, providing a critical research orientation to the Resource. We propose to accession, characterize, expand, preserve and distribute nonhuman ES cells, as well as postnatally derived stem cells from a variety of strains and species. Through a consortium arrangement under the direction of Dr. Barbara Knowles at The Jackson Laboratories, germline competency of murine ES cells will be confirmed in a quantitative manner prior to distribution, - We will also carry out Resource-related research, in partnership with Dr. James Thomson, Univ. of Wisconsin, to extensively characterize stem cells with regard to biological properties and utility of molecular tools used in stem cell research. We will standardize and opting methodology and develop new reagents in an attempt to make procedures and reagents broadly applicable across a range of species and strains. We will also establish interactive, web-based mechanisms to distribute information and technology as well as materials, and serve as a centralized source for information exchange and rapid dissemination of advances in this extremely active field.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2004 ( Subtotal = $906,610 )
2004	2004	AMERICAN TYPE CULTURE COLLECTION	10801 UNIVERSITY BOULEVARD	MANASSAS	VA	20110	MANASSAS CITY	USA	National Center for Research Resources	000	5	9/3/2004	NON-COMPETING CONTINUATION	$906,610
														Subtotal = $906,610

Issue Date FY: 2003 ( Subtotal = $880,218 )
2003	2003	AMERICAN TYPE CULTURE COLLECTION	10801 UNIVERSITY BOULEVARD	MANASSAS	VA	20110	MANASSAS CITY	USA	Comparative Medicine	000	4	9/1/2003	NON-COMPETING CONTINUATION	$880,218
														Subtotal = $880,218

Issue Date FY: 2002 ( Subtotal = $567,883 )
2002	2002	AMERICAN TYPE CULTURE COLLECTION	10801 UNIVERSITY BOULEVARD	MANASSAS	VA	20110	MANASSAS CITY	USA	Comparative Medicine	000	3	8/30/2002	NON-COMPETING CONTINUATION	$567,883
														Subtotal = $567,883

Issue Date FY: 2001 ( Subtotal = $819,381 )
2001	2001	AMERICAN TYPE CULTURE COLLECTION	10801 UNIVERSITY BOULEVARD	MANASSAS	VA	20110	MANASSAS CITY	USA	Comparative Medicine	000	2	7/23/2001	NON-COMPETING CONTINUATION	$819,381
														Subtotal = $819,381

Issue Date FY: 2000 ( Subtotal = $795,331 )
2000	2000	AMERICAN TYPE CULTURE COLLECTION	10801 UNIVERSITY BOULEVARD	MANASSAS	VA	20110	MANASSAS CITY	USA	Comparative Medicine	000	1	9/29/2000	NEW	$795,331
														Subtotal = $795,331

Grand Total All Awards = $3,969,423

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NATIONAL STEM CELL RESOURCE

Award Number: P40RR015452

ORGANIZATION: NATIONAL CENTER FOR RESEARCH RESOURCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2000

PERIOD OF PERFORMANCE END DATE: 08/31/2005

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