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COBRE Phase III: Delaware Center for Neuroscience Research

Award Number: P30GM145765
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2022
PERIOD OF PERFORMANCE END DATE: 08/31/2027

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COBRE Phase III: Delaware Center for Neuroscience Research - Overall Proposal Summary The Delaware Center for Neuroscience Research, established in 2012 with a COBRE award, is a collaboration between Delaware State University (DSU) and the University of Delaware (UD). Our unique Center brings together faculty and research resources from two very different institutions: a minority-serving, undergraduate university with an emerging strength in neuroscience research (DSU), and the state’s flagship research university (UD). Phase II of our Neuroscience Center COBRE was focused strengthening our infrastructure for neuroscience research, and to continue to support the research and professional development of early stage investigators that included Project Leads, Pilot Grant PIs, and new faculty who were hired at DSU with COBRE support. Our Center has been very successful with over 175 publications by COBRE-supported researchers, six Project Leads “graduated” into R01 support, three pilot investigator graduated to NSF grants including a CAREER award, and new faculty recruited to DSU with COBRE support winning K01 and R21 awards. During Phase II our institutions made significant investments in the research infrastructure for neuroscience. The University of Delaware established the Center for Biomedical and Brain Imaging with a 3T scanner for human magnetic resonance imaging, and a 9.4T scanner with small bore magnet for MRI with rodent models. Delaware State University established a Cell Electrophysiology Core facility to provide patch clamp, multi-electrode and automated patch clamp services with cells and tissue slices to help neuroscience investigators answer their research questions. Our phase III project will strengthen both our Center and neuroscience research in Delaware by transitioning the core resources and biomedical research activities our Neuroscience Center into independence and sustainability. The overarching scientific goal of our Neuroscience Center is to bring together and support neuroscientists working at multiple scales, from human subjects to rodent and invertebrate models to improve our understanding of the dynamic function of the brain. During Phase III we will pursue three specific aims for our Center: 1) involving a new group of investigators in the Center’s integrated mentoring and professional development program with a pilot grant program that will help junior faculty become independent, externally-funded researchers; 2) strengthening the research infrastructure and capacity in Delaware by supporting our research core facilities to transition to sustainability; and 3) to develop the Delaware Center for Neuroscience Research as a supportive, sustainable scientific community focused on investigating dynamic structure-function relationships in the brain. Continuing this COBRE program will have two significant long-term benefits. First, we will build on our success to support more Delaware neuroscientists to achieve NIH funding for their research on understanding the brain. Second, as the only COBRE based at an Historically-Black institution, our project has a uniquely significant impact in supporting diversity, equity and inclusion in the IDeA program and biomedical research in general.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,142,020 )
2025	2025	DELAWARE STATE UNIVERSITY	1200 N DUPONT HWY	DOVER	DE	19901	KENT	USA	Biomedical Research and Research Training	000	4	8/13/2025	NON-COMPETING CONTINUATION	$1,142,020
														Subtotal = $1,142,020

Issue Date FY: 2024 ( Subtotal = $1,992,477 )
2024	2024	DELAWARE STATE UNIVERSITY	1200 N DUPONT HWY	DOVER	DE	19901	KENT	USA	Biomedical Research and Research Training	001	3	9/6/2024	SUPPLEMENT FOR EXPANSION	$850,457
2024	2024	DELAWARE STATE UNIVERSITY	1200 N DUPONT HWY	DOVER	DE	19901	KENT	USA	Biomedical Research and Research Training	000	3	9/4/2024	NON-COMPETING CONTINUATION	$1,142,020
														Subtotal = $1,992,477

Issue Date FY: 2023 ( Subtotal = $1,140,268 )
2023	2023	DELAWARE STATE UNIVERSITY	1200 N DUPONT HWY	DOVER	DE	19901	KENT	USA	Biomedical Research and Research Training	000	2	8/18/2023	NON-COMPETING CONTINUATION	$1,140,268
														Subtotal = $1,140,268

Issue Date FY: 2022 ( Subtotal = $1,146,083 )
2022	2022	DELAWARE STATE UNIVERSITY	1200 N DUPONT HWY	DOVER	DE	19901	KENT	USA	Biomedical Research and Research Training	000	1	8/30/2022	NEW	$1,146,083
														Subtotal = $1,146,083

Grand Total All Awards = $5,420,848

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COBRE Phase III: Delaware Center for Neuroscience Research

Award Number: P30GM145765

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2022

PERIOD OF PERFORMANCE END DATE: 08/31/2027

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