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COBRE Phase III Transitional Center

Award Number: P30GM122733
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/15/2018
PERIOD OF PERFORMANCE END DATE: 05/31/2024

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COBRE Phase III Transitional Center - PROJECT SUMMARY/ABSTRACT The Center of Research Excellence in Natural Products Neuroscience (CORE-NPN) at The University of Mississippi School of Pharmacy (UM), initiated ten years ago through a COBRE grant, has developed a multidisciplinary team committed to evaluating the effects of natural products on the central nervous system (CNS). The Center now has the potential to develop and sustain an innovative and independently funded research center focused on treating disorders associated with the nervous system. Faculty in the Center and its academic home, the School of Pharmacy, have already reported groundbreaking observations on the roles of cannabinoids and non-cannabinoids in the etiology of weight control, the control of the immune system, treatment of cancer, control of nausea and vomiting in patients receiving anti-neoplastic treatment, glaucoma, and the development of sigma receptor agonists in the treatment of cocaine and methamphetamine abuse. Also, CORE- NPN-supported investigators have increased their competitiveness by attracting extramural funds and publishing in leading journals of neuroscience. The Center will continue to provide an excellent environment for junior and mid-level investigators through the Pilot Project Program. Investigators will work in close collaboration with leading national centers and scientists studying natural products to carry out the proposed projects that build on these novel insights into the pathophysiology of nervous system disorders. To achieve the goal of establishing an innovative and multidisciplinary Center focused on the use of natural products to manage neuropharmacological disorders, the following Specific Aims are proposed: Specific Aim 1: Administration. To enhance a sound administrative structure that offers strong mentoring for junior scientists, management of the Research Cores, workshops on grant writing/management (pre- and post-award), training in responsible conduct in research, intellectual property development, distinguished lectureship program, and promote the development of the CORE-NPN into an independent Center. Specific Aim 2: Research Core Facilities. To accelerate the research of the CORE-NPN and the associated community through state-of-the-art equipment, cutting-edge techniques, and scientific expertise. Specific Aim 3: Pilot Project Program (PPP). To advance an infrastructure of developmental programs that engage in basic, translational, and entrepreneurial research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$38,837 )
2025	2022	THE UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	000	5	11/27/2024	NON-COMPETING CONTINUATION	-$38,837
														Subtotal = -$38,837

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2022	UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	000	5	10/19/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $1,049,220 )
2022	2022	UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	001	5	6/30/2022	NON-COMPETING CONTINUATION	$1,049,220
2022	2021	UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	000	4	12/3/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,049,220

Issue Date FY: 2021 ( Subtotal = $1,060,594 )
2021	2021	UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	000	4	6/23/2021	NON-COMPETING CONTINUATION	$1,060,594
														Subtotal = $1,060,594

Issue Date FY: 2020 ( Subtotal = $1,067,817 )
2020	2020	UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	001	3	9/22/2020	NON-COMPETING CONTINUATION	$0
2020	2020	UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	000	3	5/21/2020	NON-COMPETING CONTINUATION	$1,067,817
														Subtotal = $1,067,817

Issue Date FY: 2019 ( Subtotal = $1,079,288 )
2019	2019	UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	001	2	9/26/2019	NON-COMPETING CONTINUATION	$0
2019	2019	UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	000	2	5/31/2019	NON-COMPETING CONTINUATION	$1,079,288
														Subtotal = $1,079,288

Issue Date FY: 2018 ( Subtotal = $1,090,400 )
2018	2018	UNIVERSITY OF MISSISSIPPI	113 FALKNER	UNIVERSITY	MS	38677		USA	Biomedical Research and Research Training	000	1	8/15/2018	NEW	$1,090,400
														Subtotal = $1,090,400

Grand Total All Awards = $5,308,482

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COBRE Phase III Transitional Center

Award Number: P30GM122733

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/15/2018

PERIOD OF PERFORMANCE END DATE: 05/31/2024

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