Tuesday, October 15, 2024 10/15/2024

University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment

Award Number: P30ES007033
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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ABSTRACT The theme of the UW Interdisciplinary Center for Exposures, Diseases, Genomics and Environment (EDGE Center) is "Biochemical and Molecular Mechanisms Underlying Human Variability in Response to Environmental Exposures". We envision a future in which world-class EHS research informs policy and practice to significantly reduce the burden of environmentally related diseases. The purpose of this NIEHS Core Center is to provide the administrative infrastructure and technical support necessary to foster multidisciplinary collaborations that will extend basic mechanistic studies on environmental health problems to direct applications in human populations. The EDGE Center will continue to have an emphasis on “gene x environment” interactions, with an increased emphasis on development and integration of EHS for public health decision-making. This Center consists of 59 Environmental Health Sciences (EHS) Core investigators and 35 other investigators involved in Clinical and Translational Sciences (CTS) research at the UW, organized into 5 disease-based Collaborative Research Teams (CRTs): 1) Environment & Cancer; 2) Developmental & Reproductive Disorders; 3) Neurodegenerative Diseases; 4) Cardiopulmonary & Metabolic Diseases; and 5) Hepatic, Renal & Gastrointestinal Diseases. The outstanding research of UW EHS Core faculty is enhanced by 3 Facility Cores. 1) The Integrative Environmental Health Sciences Facility Core fosters clinical and translational population-based research and disaster research response activities. 2) The Genomics, Bioinformatics & Biostatistics and Microphysiological Systems Core enables Center members to utilize OMICs technologies and provides rigorous analysis of the data. It also provides access to in vitro systems that mimic complex tissue architecture suitable for investigating organ-like physiology in the context of toxicological perturbations. 3) The Exposure Assessment, Biomarkers & Environmental Sensing Core offers state-of-the-art exposure assessment tools and approaches. In addition, the Center supports exploratory research projects into innovative new ideas related to the theme of the Center each year through a Pilot Projects Program as well as mini-pilot grants throughout the year. The Community Engagement Core provides a mechanism to connect Center investigators, community partners, and other stakeholders in productive bi-directional EHS-focused dialogue and activities. The resources available through the EDGE Center have assisted members in achieving their fullest potential as EHS investigators. Center involvement has resulted in numerous publications, research grants, and training opportunities. Of the 94 current EDGE members, 37 are Principal Investigators on 65 grants that will be active as of May 31, 2021. The total annual direct costs for these grants are slightly over $36 M, of which approximately 83% ($30 M) is from NIH. EDGE faculty members are PIs on 11 current NIEHS grants that will still be active as of May 31, 2021.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $1,473,148 )
2024	2024	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	001	29	3/1/2024	NON-COMPETING CONTINUATION	$1,473,148
2024	2023	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	000	28	12/13/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,473,148

Issue Date FY: 2023 ( Subtotal = $1,495,739 )
2023	2023	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	002	28	3/30/2023	NON-COMPETING CONTINUATION	$0
2023	2023	THE UNIVERSITY OF WASHINGTON VICE PR	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	003	28	9/27/2023	NON-COMPETING CONTINUATION	$0
2023	2023	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	001	28	3/2/2023	NON-COMPETING CONTINUATION	$1,495,739
2023	2022	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	000	27	2/7/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,495,739

Issue Date FY: 2022 ( Subtotal = $1,524,967 )
2022	2022	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	003	27	2/28/2022	NON-COMPETING CONTINUATION	$1,524,967
2022	2021	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	000	26	11/10/2021	COMPETING CONTINUATION	$0
2022	2021	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	002	26	12/3/2021	COMPETING CONTINUATION	$477,829
2022	2020	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	001	25	12/3/2021	NON-COMPETING CONTINUATION	-$477,829
														Subtotal = $1,524,967

Issue Date FY: 2021 ( Subtotal = $1,555,000 )
2021	2021	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	001	26	5/31/2021	COMPETING CONTINUATION	$1,555,000
2021	2020	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	000	25	5/21/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,555,000

Issue Date FY: 2020 ( Subtotal = $1,593,990 )
2020	2020	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	001	25	4/1/2020	NON-COMPETING CONTINUATION	$1,593,990
2020	2019	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	000	24	11/18/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,593,990

Issue Date FY: 2019 ( Subtotal = $1,655,552 )
2019	2019	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	002	24	8/8/2019	SUPPLEMENT FOR EXPANSION	$15,550
2019	2019	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	003	24	9/10/2019	SUPPLEMENT FOR EXPANSION	$45,857
2019	2019	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	001	24	4/1/2019	NON-COMPETING CONTINUATION	$1,594,145
2019	2018	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	000	23	10/29/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,655,552

Issue Date FY: 2018 ( Subtotal = $1,594,454 )
2018	2018	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	000	23	3/23/2018	NON-COMPETING CONTINUATION	$1,594,454
														Subtotal = $1,594,454

Issue Date FY: 2017 ( Subtotal = $1,753,578 )
2017	2017	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	005	22	9/16/2017	SUPPLEMENT FOR EXPANSION	$53,732
2017	2017	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	003	22	9/14/2017	SUPPLEMENT FOR EXPANSION	$77,500
2017	2017	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	002	22	3/30/2017	NON-COMPETING CONTINUATION	$1,544,846
2017	2017	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	004	22	9/15/2017	SUPPLEMENT FOR EXPANSION	$77,500
2017	2016	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	001	21	11/28/2016	COMPETING CONTINUATION	$15,187
2017	2015	UNIVERSITY OF WASHINGTON	4333 BROOKLYN AVE NE	SEATTLE	WA	98195	KING	USA	Environmental Health	000	20	11/28/2016	NON-COMPETING CONTINUATION	-$15,187
														Subtotal = $1,753,578

Issue Date FY: 2016 ( Subtotal = $1,707,225 )
2016	2016	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	003	21	9/20/2016	SUPPLEMENT FOR EXPANSION	$77,250
2016	2016	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	001	21	6/13/2016	COMPETING CONTINUATION	$1,545,000
2016	2016	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	002	21	9/19/2016	SUPPLEMENT FOR EXPANSION	$84,975
2016	2015	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	000	20	6/8/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,707,225

Issue Date FY: 2015 ( Subtotal = $1,712,755 )
2015	2015	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	000	20	4/1/2015	NON-COMPETING CONTINUATION	$1,712,755
														Subtotal = $1,712,755

Issue Date FY: 2014 ( Subtotal = $1,714,772 )
2014	2014	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	000	19	4/1/2014	NON-COMPETING CONTINUATION	$1,714,772
														Subtotal = $1,714,772

Issue Date FY: 2013 ( Subtotal = $1,774,602 )
2013	2013	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	001	18	5/14/2013	SUPPLEMENT FOR EXPANSION	$20,757
2013	2013	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	000	18	4/10/2013	NON-COMPETING CONTINUATION	$1,544,402
2013	2013	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	003	18	9/16/2013	SUPPLEMENT FOR EXPANSION	$72,165
2013	2013	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	002	18	7/9/2013	NON-COMPETING CONTINUATION	$137,278
														Subtotal = $1,774,602

Issue Date FY: 2012 ( Subtotal = $1,716,000 )
2012	2012	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Environmental Health	000	17	4/13/2012	NON-COMPETING CONTINUATION	$1,716,000
														Subtotal = $1,716,000

Issue Date FY: 2011 ( Subtotal = $1,698,601 ) (Continued on the next page)
Grand Total All Awards = $39,796,312

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University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment

Award Number: P30ES007033

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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