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UAB Diabetes Research Center

Award Number: P30DK079626
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2008
PERIOD OF PERFORMANCE END DATE: 05/31/2028

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UAB Diabetes Research Center - This proposal will continue progress of the UAB DRC first established in 2008. Our mission is: “Alleviate suffering and the social burden caused by diabetes and cardiometabolic disease through innovative, multidisciplinary, basic and translational research and research training, which advances understanding of disease mechanisms, prevention, and treatment”. Over 14 years, the DRC has galvanized the UAB research efforts around the study of diabetes and established an outstanding research community that has grown to 150 scientific investigators with current extramural diabetes research funding of $91,388,610 annual direct costs. Our center’s goals are to facilitate excellence in diabetes research, further develop a cohesive intellectual community promoting collaboration and innovation, and provide an outstanding environment for training and career development. Our research emphasizes the study of diabetes as both a metabolic and vascular disease and includes areas of research excellence including molecular signaling, islet biology & autoimmunity, integrative metabolism, vascular disease/inflammation, diabetes complications, genetics & epidemiology, and interventions & community based research. Our specific aims are to: 1. Facilitate and enhance diabetes research by sponsoring research core facilities expressly required by our investigator base and that cover a broad translational spectrum: Animal Physiology, Human Physiology, and Interventions & Translation Cores. 2. Augment diabetes research via a pilot & feasibility grant program that will emphasize innovation, translation, and career development of highly promising junior investigators. 3. Sponsor an integrated Enrichment Program that promotes a cohesive environment for an outstanding multi-disciplinary investigator base, which will enhance learning, training, collaboration, collegiality, and innovation. 4. Emphasize research and outreach that are responsive to the needs of our trainees, achieve better outcomes for our patients, and lessen the high burden of diabetes in our community and nation. 5. Respond to the evolving needs of our investigators and through leadership that impels new ideas and lines of investigation, and leverage the resolve of UAB leadership, substantial institutional commitments, and generous philanthropy from our community to further impel the development of a pre-eminent center of diabetes research excellence in the heart of the Deep South. The DRC has exerted a pronounced impact on diabetes research excellence at UAB in a community with the highest rates of diabetes in the US, and has united investigators around common themes to study diabetes in the context of cardiometabolic disease. We are confident that further evolution and growth will be achieved over the next 5 years.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $1,281,325 )
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	003	17	6/18/2024	NON-COMPETING CONTINUATION	$1,281,325
2024	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	16	6/17/2024	COMPETING CONTINUATION	$547,397
2024	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	15	6/17/2024	SUPPLEMENT FOR EXPANSION	-$30,807
2024	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	15	6/17/2024	NON-COMPETING CONTINUATION	-$516,590
														Subtotal = $1,281,325

Issue Date FY: 2023 ( Subtotal = $1,355,575 )
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	16	6/21/2023	COMPETING CONTINUATION	$1,281,325
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	16	6/23/2023	SUPPLEMENT FOR EXPANSION	$74,250
2023	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	15	11/1/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,355,575

Issue Date FY: 2022 ( Subtotal = $1,319,332 )
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	15	7/22/2022	NON-COMPETING CONTINUATION	$1,245,082
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	003	15	8/24/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	15	7/25/2022	SUPPLEMENT FOR EXPANSION	$74,250
2022	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	12	4/1/2022	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,319,332

Issue Date FY: 2021 ( Subtotal = $1,245,082 )
2021	2021	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	14	9/9/2021	NON-COMPETING CONTINUATION	$1,245,082
2021	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	12	8/13/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	12	3/10/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,245,082

Issue Date FY: 2020 ( Subtotal = $1,245,082 )
2020	2020	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	13	6/5/2020	NON-COMPETING CONTINUATION	$1,245,082
														Subtotal = $1,245,082

Issue Date FY: 2019 ( Subtotal = $2,177,626 )
2019	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	003	12	9/13/2019	SUPPLEMENT FOR EXPANSION	$932,545
2019	2019	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	12	7/10/2019	NON-COMPETING CONTINUATION	$1,245,082
2019	2018	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	11	7/10/2019	COMPETING CONTINUATION	$0
2019	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	10	2/1/2019	NON-COMPETING CONTINUATION	-$1
														Subtotal = $2,177,626

Issue Date FY: 2018 ( Subtotal = $1,271,524 )
2018	2018	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	11	8/28/2018	COMPETING CONTINUATION	$1,271,524
2018	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	10	8/23/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,271,524

Issue Date FY: 2017 ( Subtotal = $1,143,110 )
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	10	1/26/2017	NON-COMPETING CONTINUATION	$1,028,798
2017	2017	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	10	6/15/2017	NON-COMPETING CONTINUATION	$114,312
														Subtotal = $1,143,110

Issue Date FY: 2016 ( Subtotal = $1,143,110 )
2016	2016	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	9	3/16/2016	EXTENSION WITH OR WITHOUT FUNDS	$1,143,110
														Subtotal = $1,143,110

Issue Date FY: 2015 ( Subtotal = $1,143,442 )
2015	2015	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	8	2/10/2015	NON-COMPETING CONTINUATION	$1,143,442
														Subtotal = $1,143,442

Issue Date FY: 2014 ( Subtotal = $1,148,922 )
2014	2014	UNIVERSITY OF ALABAMA AT BIRMINGHAM	1530 3rd Avenue South, AB 1170	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	7	7/24/2014	NON-COMPETING CONTINUATION	$1,148,922
														Subtotal = $1,148,922

Issue Date FY: 2013 ( Subtotal = $1,133,433 )
2013	2013	UNIVERSITY OF ALABAMA AT BIRMINGHAM	UAB STATION, CBB 990	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	6	9/5/2013	COMPETING CONTINUATION	$99,404
2013	2013	UNIVERSITY OF ALABAMA AT BIRMINGHAM	UAB STATION, CBB 990	BIRMINGHAM	AL	35294	JEFFERSON	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	6	3/21/2013	COMPETING CONTINUATION	$1,034,029
														Subtotal = $1,133,433

Grand Total All Awards = $15,607,563

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UAB Diabetes Research Center

Award Number: P30DK079626

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2008

PERIOD OF PERFORMANCE END DATE: 05/31/2028

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