Tuesday, July 1, 2025 7/1/2025

Center for Gastrointestinal Biology and Disease

Award Number: P30DK034987
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 12/01/1996
PERIOD OF PERFORMANCE END DATE: 11/30/2024

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Center for Gastrointestinal Biology and Disease - PROJECT SUMMARY The burden of gastrointestinal, liver and pancreatic diseases in the US exceeds $135 billion. The overall mission of the Center for Gastrointestinal Biology and Disease (CGIBD) is to promote multidisciplinary research to reduce the burden of digestive diseases. The Center achieves this mission through the following: 1) Core facilities that provide new technologies, expertise, training, technical assistance, laboratory animals, biostatistical and clinical research support. 2) A pilot/feasibility program that provides startup funds to promising investigators. 3) A scientific enrichment program consisting of seminars, special lectures, workshops and competitions for trainees that improve the intellectual climate for gastrointestinal biological research. 4) A professional development and training program that fosters the careers of junior faculty and trainees. Members of the CGIBD are basic and clinical scientists from diverse disciplines dedicated to advancing our understanding of the biology, physiology and epidemiology of digestive diseases. The overarching theme for the Center is Homeostasis, Injury and Repair, a theme that encompasses the wide range of digestive disease research conducted by the membership. Within the theme, members cluster into three areas of research focus: microbiome, clinical/translational research, regenerative medicine/repair. The research base includes 47 full members and 9 associate members from 22 departments. The annual direct costs for digestive disease-related grants to members total $27.9 million. To support the research of members, the Center proposes an Administrative Core to organize the activities of the Center and the following scientific cores: 1) Advanced Analytics; 2) Biostatistics and Clinical Research; 3) Gnotobiotic Animal; 4) Large Animal Models. These cores have evolved to support the scientific directions of center members and to provide new investigative opportunities. The cores improve efficiency, lower cost, and provide services that would not otherwise be available to investigators. Through all of its activities, the Center improves communication, promotes collaboration, develops careers, and generally enriches the environment for digestive disease research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$247,297 )
2025	2024	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	39	4/22/2025	NON-COMPETING CONTINUATION	-$247,297
														Subtotal = -$247,297

Issue Date FY: 2024 ( Subtotal = $1,126,470 )
2024	2024	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	39	12/15/2023	NON-COMPETING CONTINUATION	$1,013,823
2024	2024	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	39	5/20/2024	NON-COMPETING CONTINUATION	$112,647
														Subtotal = $1,126,470

Issue Date FY: 2023 ( Subtotal = $1,126,470 )
2023	2023	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	38	1/5/2023	NON-COMPETING CONTINUATION	$112,647
2023	2023	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	38	12/7/2022	NON-COMPETING CONTINUATION	$1,013,823
														Subtotal = $1,126,470

Issue Date FY: 2022 ( Subtotal = $1,126,470 )
2022	2022	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	37	11/16/2021	NON-COMPETING CONTINUATION	$1,013,823
2022	2022	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	37	3/30/2022	NON-COMPETING CONTINUATION	$112,647
														Subtotal = $1,126,470

Issue Date FY: 2021 ( Subtotal = $1,126,470 )
2021	2021	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	36	3/1/2021	NON-COMPETING CONTINUATION	$22,530
2021	2021	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	36	2/8/2021	NON-COMPETING CONTINUATION	$90,117
2021	2021	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	36	11/24/2020	NON-COMPETING CONTINUATION	$1,013,823
														Subtotal = $1,126,470

Issue Date FY: 2020 ( Subtotal = $1,154,222 )
2020	2020	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	004	35	9/26/2020	COMPETING CONTINUATION	$237,783
2020	2020	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	35	3/25/2020	COMPETING CONTINUATION	$0
2020	2020	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	35	3/11/2020	COMPETING CONTINUATION	$1,154,222
2020	2019	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	003	34	9/26/2020	NON-COMPETING CONTINUATION	-$237,783
2020	2019	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	34	3/3/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,154,222

Issue Date FY: 2019 ( Subtotal = $1,064,646 )
2019	2019	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	34	12/13/2018	NON-COMPETING CONTINUATION	$1,043,353
2019	2019	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	34	8/27/2019	NON-COMPETING CONTINUATION	$21,293
														Subtotal = $1,064,646

Issue Date FY: 2018 ( Subtotal = $1,035,494 )
2018	2018	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	33	11/23/2017	NON-COMPETING CONTINUATION	$958,181
2018	2018	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	33	6/7/2018	NON-COMPETING CONTINUATION	$77,313
														Subtotal = $1,035,494

Issue Date FY: 2017 ( Subtotal = $1,064,646 )
2017	2017	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	32	6/14/2017	NON-COMPETING CONTINUATION	$106,465
2017	2017	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	104 AIRPORT DR STE 2200	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	32	11/29/2016	NON-COMPETING CONTINUATION	$958,181
														Subtotal = $1,064,646

Issue Date FY: 2016 ( Subtotal = $1,065,525 )
2016	2016	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	31	12/21/2015	NON-COMPETING CONTINUATION	$958,973
2016	2016	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	31	3/8/2016	NON-COMPETING CONTINUATION	$106,552
														Subtotal = $1,065,525

Issue Date FY: 2015 ( Subtotal = $1,102,766 )
2015	2015	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	30	2/18/2015	COMPETING CONTINUATION	$1,102,766
2015	2014	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	29	2/13/2015	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,102,766

Issue Date FY: 2014 ( Subtotal = $1,111,150 )
2014	2014	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	29	3/14/2014	NON-COMPETING CONTINUATION	$84,825
2014	2014	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	29	9/3/2014	NON-COMPETING CONTINUATION	$31,864
2014	2014	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	29	12/5/2013	NON-COMPETING CONTINUATION	$994,461
														Subtotal = $1,111,150

Issue Date FY: 2013 ( Subtotal = $1,045,286 )
2013	2013	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	28	5/17/2013	NON-COMPETING CONTINUATION	$50,825
2013	2013	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	28	11/1/2012	NON-COMPETING CONTINUATION	$994,461
														Subtotal = $1,045,286

Issue Date FY: 2012 ( Subtotal = $1,111,150 )
2012	2012	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	27	2/14/2012	NON-COMPETING CONTINUATION	$110,493
2012	2012	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	27	9/26/2012	NON-COMPETING CONTINUATION	$6,195
2012	2012	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	27	11/16/2011	NON-COMPETING CONTINUATION	$994,462
														Subtotal = $1,111,150

Issue Date FY: 2011 ( Subtotal = $1,104,955 )
2011	2011	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	26	12/1/2010	NON-COMPETING CONTINUATION	$1,000,035
2011	2011	UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	440 WEST FRANKLIN ST, CB #1350	CHAPEL HILL	NC	27599	ORANGE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	26	5/27/2011	NON-COMPETING CONTINUATION	$104,920
														Subtotal = $1,104,955

Grand Total All Awards = $28,671,025

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Center for Gastrointestinal Biology and Disease

Award Number: P30DK034987

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 12/01/1996

PERIOD OF PERFORMANCE END DATE: 11/30/2024

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