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 | Issue Date FY: 2025 ( Subtotal = $140,857,842 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01AI176596 | Identifying Roadblocks to Antigen Expression and Enhancing Killing of HIV-Infected Cells That Are Refractory to Clearance | 000 | 3 | NIH | 2/18/2025 | $832,909 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01AI176596 | Identifying Roadblocks to Antigen Expression and Enhancing Killing of HIV-Infected Cells That Are Refractory to Clearance | 000 | 3 | NIH | 2/18/2025 | $100,000 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R21MH140292 | Types of green spaces and the development of anxiety, depression, and ADHD in rural, low-income communities | 000 | 1 | NIH | 3/26/2025 | $421,067 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | UG1CA233373 | UNC Lead Academic Participating Site | 000 | 6 | NIH | 3/5/2025 | $303,121 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01NS129914 | Investigating UBE3A as a driver gene in Duplication 15q syndrome | 000 | 3 | NIH | 3/6/2025 | $363,931 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01NS117133 | Unexpected Function of Inflammasomes in Axon Pruning: Focus on NLRP1 | 000 | 3 | NIH | 3/5/2025 | $492,776 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01AG075884 | Immune Cells in Alzheimer’s Disease and Related Dementias in the Jackson Heart Study | 000 | 4 | NIH | 3/5/2025 | $675,068 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01MH136149 | 1/3 Eating Disorders Genetics Initiative 2 (EDGI2) | 000 | 2 | NIH | 3/27/2025 | $1,634,466 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01MH112205 | Molecular Details of Psychoactive Drug Actions | 000 | 9 | NIH | 3/6/2025 | $509,852 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01EY032520 | Vascular dysfunction in glaucoma | 003 | 4 | NIH | 3/27/2025 | $388,750 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01CA253450 | P53, DNA Repair Imbalance, and Immune Response in Breast Cancer Mortality Disparities | 000 | 5 | NIH | 3/27/2025 | $523,566 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R35GM152079 | Gut Microbial Enzymes and Human Disease | 001 | 2 | NIH | 2/20/2025 | $482,601 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01NS122230 | Determining the impact of BNST CRF systems on inflammatory pain-induced disruptions of behavior | 000 | 5 | NIH | 3/26/2025 | $355,837 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R34AR083077 | STepped Exercise Program for Knee Osteoarthritis: The STEP-KOA Study | 000 | 2 | NIH | 2/19/2025 | $122,648 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01AI175708 | Antiviral and immunomodulatory effects of interferon lambda in the skin | 000 | 3 | NIH | 3/10/2025 | $594,722 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R35HL155657 | Tissue factor-dependent coagulation in thrombosis and immune responses | 000 | 5 | NIH | 2/21/2025 | $839,700 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01AG077947 | Multilevel Forms of Structural Racism and Racial Inequalities in ADRD Risk | 000 | 4 | NIH | 3/11/2025 | $634,005 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01AI169461 | Human Antibody Cross-Reactivity in Non-Polio Enteroviruses | 000 | 4 | NIH | 3/22/2025 | $611,746 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | F31HD111292 | Dissecting mechanisms of gene silencing by the lncRNA Kcnq1ot1 in mouse trophoblast stem cells | 000 | 3 | NIH | 3/7/2025 | $42,234 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01AG044034 | Oxidative Stress and the Development of Osteoarthritis | 000 | 13 | NIH | 3/7/2025 | $368,168 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R50CA275929 | Curing Through Collaboration: Utilizing Cooperative Groups in the Fight Against Chronic Lymphocytic Leukemia and B-cell Lymphomas | 002 | 4 | NIH | 2/28/2025 | $168,361 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01CA233037 | The novel role of microtubule regulators in the DNA damage response | 000 | 5 | NIH | 2/28/2025 | $208,281 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | K24ES031131 | Patient-oriented research and mentoring in preterm birth toxicogenomics | 000 | 5 | NIH | 2/14/2025 | $163,581 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01HL146626 | Regulation of cardiac pacemaker cell cytoarchitecture | 002 | 7 | NIH | 3/25/2025 | $541,509 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01AI168242 | Novel strategy to block Nabs for AAV gene delivery | 000 | 4 | NIH | 3/10/2025 | $601,627 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R37CA230786 | Function of IL35+ B cells in pancreatic cancer | 000 | 7 | NIH | 3/3/2025 | $375,321 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01CA276663 | Developmental control of chromatin states in cancer | 000 | 3 | NIH | 3/4/2025 | $382,238 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01CA281295 | KRAS G12C: Kinetic and Redox Characterization of Covalent Inhibition | 000 | 3 | NIH | 3/4/2025 | $512,164 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | D43TW011548 | Vietnam Implementation Science Advancement: A Training Program to Improve HIV Prevention and Care | 000 | 5 | NIH | 3/10/2025 | $126,864 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | D43TW011548 | Vietnam Implementation Science Advancement: A Training Program to Improve HIV Prevention and Care | 000 | 5 | NIH | 3/10/2025 | $100,000 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | D43TW011548 | Vietnam Implementation Science Advancement: A Training Program to Improve HIV Prevention and Care | 000 | 5 | NIH | 3/10/2025 | $25,000 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | D43TW011548 | Vietnam Implementation Science Advancement: A Training Program to Improve HIV Prevention and Care | 000 | 5 | NIH | 3/10/2025 | $50,000 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01CA247652 | Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer Tumors | 000 | 5 | NIH | 3/4/2025 | $500,267 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01HL174038 | Maximizing Therapeutic Accumulation and Retention for Enhanced Cardiac Repair | 000 | 2 | NIH | 3/11/2025 | $623,558 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01ES034260 | Regulatory Genomics of Ozone Air Pollution Response in Vitro and In Vivo | 000 | 4 | NIH | 3/4/2025 | $637,686 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01ES031940 | Epidemiologic identification and mechanistic investigation of early life environmental risk factors for eosinophilic esophagitis | 000 | 5 | NIH | 3/4/2025 | $625,444 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | OT2OD031940 | A Strategy for Heal Federated Data Ecosystem | 001 | 1 | NIH | 2/21/2025 | $2,550,015 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | OT2OD031940 | A Strategy for Heal Federated Data Ecosystem | 001 | 1 | NIH | 2/21/2025 | $1,847,736 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01CA292625 | Targeting APOBEC3-induced squamous differentiation in bladder cancer | 000 | 1 | NIH | 2/25/2025 | $514,582 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01MH123747 | The Development of Individual Differences in Adolescent Brain Structure and Risk | 000 | 5 | NIH | 3/21/2025 | $605,469 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01CA259077 | Novel TYRO3 inhibitors for treatment of cancer | 000 | 5 | NIH | 3/3/2025 | $290,773 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01CA290597 | Triggering Aberrant RNA Processing for RCC Therapy | 000 | 2 | NIH | 3/3/2025 | $556,251 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | U01AI182180 | Development of a recombinant protein vaccine for Chlamydia trachomatis | 000 | 2 | NIH | 3/21/2025 | $1,925,693 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01DK128174 | My weight-their weight: eHealth intervention for managing obesity in child care settings | 000 | 4 | NIH | 2/17/2025 | $569,131 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01AI107029 | Phase variation of virulence factors in Clostridioides difficile | 002 | 11 | NIH | 2/24/2025 | $5,448 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | F31DK137574 | Using molecular quantitative trait loci mapping approaches to determine candidate gene regulatory mechanisms of functional variants within inflammatory bowel disease GWAS loci. | 000 | 2 | NIH | 2/14/2025 | $42,574 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | U01AG082042 | Proteomic biomarkers of incident cognitive impairment in Black and White adults | 000 | 2 | NIH | 3/25/2025 | $667,946 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | R01CA278961 | Bioinstructive Scaffolds for Potent and Affordable CAR-T Cell Therapy Against Brain Tumors | 002 | 3 | NIH | 2/28/2025 | $570,785 |
| | 2025 | 2025 | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 104 AIRPORT DR STE 2200 | CHAPEL HILL | NC | 27599-5023 | ORANGE | USA | F32ES035271 | Evolution and underlying genetics of thermal physiology and behavior in Drosophila | 000 | 2 | NIH | 3/24/2025 | $76,756 |
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