Tuesday, May 20, 2025 5/20/2025

Cancer Center Support Grant

Award Number: P30CA091842
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Cancer Center Support Grant - DESCRIPTION (provided by applicant): For more than 25 years, the immunology community in Siteman Cancer Center (SCC) at Washington University School of Medicine (WUSM) has been known for the significant breadth and depth of its contributions to the field of immunology and for its highly interactive nature. Fifteen years ago, a strategic decision was made to promote basic science research in tumor immunology and establish an infrastructure to facilitate clinical translation of cancer immunotherapies at SCC through the creation of a Tumor Immunology Program (TIP) as an integral component of a newly-forming NCI-designated Comprehensive Cancer Center. This strategic decision has proved to be prescient, and today the number of laboratories at SCC performing tumor immunology-related research has increased significantly. Of particular note, in the last five years there has been an increase in the number of laboratories performing translational tumor immunology research and a number of investigator-initiated cancer clinical trials are ongoing. Importantly, this increase in translational research has been achieved through the creation of an environment where interactions between basic scientists and physician scientists occur easily and often and where state-of-the-art resources are available to facilitate translation of basic science research findings into novel therapeutic opportunities. Thus, as a result of the environment that was established by the Siteman Cancer Center, the highly interactive nature of the basic immunology research community now extends to the work being performed in the areas of tumor immunology and cancer immunotherapy. Efforts of Tumor Immunology Program members are currently focused into four central themes: (1) the dynamic interplay between the immune system and cancer, (2) the molecular basis of immune recognition of cancer, (3) the impact of inflammation and immunosuppression on cancer development and (4) cancer immunotherapy. The Tumor Immunology Program has 34 members from 5 departments and 1 school at Washington University. The program is supported by $15.8 million in funding, of which $3.3 million is from NCI and $8.4 million is other peer-reviewed funding. In the last grant period, members of the program published 602 manuscripts, of which 24% represent inter-programmatic and 15% resulted from intra-programmatic collaborations. During the last funding period, TIP had 682 total enrollments onto 45 clinical studies: 67% were therapeutic, and 27% were early phase. Accrual to investigator-initiated trials was 30%.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $6,348,720 )
2024	2024	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	Cancer Centers Support Grants	002	23	8/9/2024	NON-COMPETING CONTINUATION	$0
2024	2024	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	Cancer Centers Support Grants	001	23	6/28/2024	NON-COMPETING CONTINUATION	$6,073,063
2024	2024	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	Cancer Centers Support Grants	005	23	8/28/2024	SUPPLEMENT FOR EXPANSION	$200,000
2024	2024	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	Cancer Centers Support Grants	004	23	8/26/2024	SUPPLEMENT FOR EXPANSION	$60,000
2024	2024	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63110	SAINT LOUIS CITY	USA	Cancer Centers Support Grants	003	23	8/14/2024	SUPPLEMENT FOR EXPANSION	$194,375
2024	2019	WASHINGTON UNIVERSITY, THE	1 BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	000	18	10/1/2023	SUPPLEMENT FOR EXPANSION	-$178,718
														Subtotal = $6,348,720

Issue Date FY: 2023 ( Subtotal = $6,766,388 )
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	003	22	9/4/2023	SUPPLEMENT FOR EXPANSION	$149,994
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	004	22	9/14/2023	SUPPLEMENT FOR EXPANSION	$198,993
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	001	22	7/14/2023	SUPPLEMENT FOR EXPANSION	$194,375
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	000	22	6/13/2023	NON-COMPETING CONTINUATION	$6,073,063
2023	2023	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	002	22	9/1/2023	SUPPLEMENT FOR EXPANSION	$149,963
														Subtotal = $6,766,388

Issue Date FY: 2022 ( Subtotal = $6,353,563 )
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	002	21	8/26/2022	SUPPLEMENT FOR EXPANSION	$220,500
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	001	21	8/25/2022	SUPPLEMENT FOR EXPANSION	$60,000
2022	2022	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	000	21	8/23/2022	NON-COMPETING CONTINUATION	$6,073,063
2022	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	003	20	9/12/2022	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $6,353,563

Issue Date FY: 2021 ( Subtotal = $6,406,113 )
2021	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	005	20	9/23/2021	SUPPLEMENT FOR EXPANSION	$150,000
2021	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	003	20	6/25/2021	SUPPLEMENT FOR EXPANSION	$123,050
2021	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	004	20	6/28/2021	SUPPLEMENT FOR EXPANSION	$60,000
2021	2021	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	002	20	6/15/2021	NON-COMPETING CONTINUATION	$6,073,063
2021	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	001	19	1/8/2021	COMPETING CONTINUATION	$148,996
2021	2019	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	000	18	1/8/2021	SUPPLEMENT FOR EXPANSION	-$148,996
														Subtotal = $6,406,113

Issue Date FY: 2020 ( Subtotal = $6,688,909 )
2020	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	001	19	7/17/2020	COMPETING CONTINUATION	$0
2020	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	003	19	8/28/2020	SUPPLEMENT FOR EXPANSION	$99,849
2020	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	005	19	9/14/2020	SUPPLEMENT FOR EXPANSION	$190,997
2020	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	004	19	9/11/2020	SUPPLEMENT FOR EXPANSION	$200,000
2020	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	002	19	8/14/2020	SUPPLEMENT FOR EXPANSION	$125,000
2020	2020	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	000	19	7/15/2020	COMPETING CONTINUATION	$6,073,063
														Subtotal = $6,688,909

Issue Date FY: 2019 ( Subtotal = $4,756,339 )
2019	2019	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	001	18	7/1/2019	SUPPLEMENT FOR EXPANSION	$250,626
2019	2019	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	000	18	6/28/2019	NON-COMPETING CONTINUATION	$4,305,712
2019	2019	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	002	18	9/2/2019	SUPPLEMENT FOR EXPANSION	$200,001
														Subtotal = $4,756,339

Issue Date FY: 2018 ( Subtotal = $5,028,355 )
2018	2018	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	004	17	8/28/2018	SUPPLEMENT FOR EXPANSION	$199,999
2018	2018	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	002	17	8/13/2018	NON-COMPETING CONTINUATION	$0
2018	2018	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	17	6/29/2018	SUPPLEMENT FOR EXPANSION	$240,897
2018	2018	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	003	17	8/27/2018	SUPPLEMENT FOR EXPANSION	$254,917
2018	2018	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	005	17	8/29/2018	SUPPLEMENT FOR EXPANSION	$124,730
2018	2018	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	000	17	6/28/2018	NON-COMPETING CONTINUATION	$4,207,812
														Subtotal = $5,028,355

Issue Date FY: 2017 ( Subtotal = $4,672,483 )
2017	2017	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	002	16	9/20/2017	SUPPLEMENT FOR EXPANSION	$243,947
2017	2017	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	000	16	6/22/2017	NON-COMPETING CONTINUATION	$4,305,712
2017	2017	WASHINGTON UNIVERSITY, THE	ONE BROOKINGS DR	SAINT LOUIS	MO	63130	SAINT LOUIS	USA	Cancer Centers Support Grants	001	16	6/30/2017	SUPPLEMENT FOR EXPANSION	$122,824
														Subtotal = $4,672,483

Issue Date FY: 2016 ( Subtotal = $5,077,655 ) (Continued on the next page)
2016	2016	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Centers Support Grants	003	15	7/11/2016	NON-COMPETING CONTINUATION	$4,305,712
2016	2016	WASHINGTON UNIVERSITY	CAMPUS BOX 1034	SAINT LOUIS	MO	63112	SAINT LOUIS CITY	USA	Cancer Centers Support Grants	004	15	7/20/2016	SUPPLEMENT FOR EXPANSION	$124,686
Grand Total All Awards = $109,286,082

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Cancer Center Support Grant

Award Number: P30CA091842

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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