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Case Comprehensive Cancer Center Support Grant

Award Number: P30CA043703
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/01/1997
PERIOD OF PERFORMANCE END DATE: 05/31/2030

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Case Comprehensive Cancer Center Support Grant - PROJECT SUMMARY/ABSTRACT The mission of the Case Comprehensive Cancer Center (Case CCC), now in its 34th grant year, is to develop high-impact and comprehensive cancer research programs in an environment that fosters scientific discovery, spans prevention, facilitates early detection, stratifies risk, promotes therapies, and finds cures to ultimately improve lives across its communities. The Case CCC’s geographic outreach addresses the individual needs of patients in the catchment area. This approach empowers innovation and discovery in clinical care reflecting an unyielding commitment to reducing health care disparities and impacting cancer care in the catchment area and worldwide. The Center coordinates all aspects of cancer research in Cleveland and Northern Ohio, including activities of the affiliate institutions of Case Western Reserve University, Cleveland Clinic, and University Hospitals. The Case CCC is organized around 6 Research Programs, 10 Shared Resources, and a clinical and behavioral cancer research infrastructure that prioritizes innovative translational research and investigator-initiated clinical trials that cut across the Research Programs. The Center promotes the education and training of the next generation of cancer-focused scientists and healthcare professionals and seeks to promote a research community distinguished by academic and organizational excellence. The Case CCC includes 288 full members from 8 schools and 46 academic departments who actively participate in Center activities which promote a transdisciplinary approach that facilitates discovery and clinical application. The cancer focus of the Center is exceptional, with over $87M in direct funding and over $30M in direct NCI funding. Institutional commitment is also exceptional, codified through an updated Memorandum of Understanding. The consortium members will provide over $220M of internal funds for cancer research in the next grant cycle. The Case CCC and its affiliate institutions have established an outstanding infrastructure that enables its members to improve the prevention, diagnosis, and treatment of cancer through discovery, implementation and dissemination, and collaborative transdisciplinary research while providing state-of-the-art care and treatment to cancer patients and their families. Case CCC members identify new therapeutic targets, make drug discoveries, develop new imaging tools, and pursue innovative clinical trials with novel small molecules and immune therapeutics. The core principles of the Case CCC are reflected in the updated Strategic Plan, including bi-directional engagement to build trust within the community. The Case CCC yields tangible benefits as an active partner with the NCI by supporting cancer relevant scientific research with direct benefit to patients and the general public.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $5,105,872 )
2025	2025	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	001	35	6/16/2025	COMPETING CONTINUATION	$5,105,872
2025	2024	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	000	34	6/16/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $5,105,872

Issue Date FY: 2024 ( Subtotal = $5,922,322 )
2024	2024	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	003	34	9/4/2024	SUPPLEMENT FOR EXPANSION	$249,131
2024	2024	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	002	34	4/29/2024	NON-COMPETING CONTINUATION	$5,673,191
2024	2023	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	001	33	4/24/2024	EXTENSION WITH OR WITHOUT FUNDS	$851,236
2024	2022	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	000	32	4/24/2024	NON-COMPETING CONTINUATION	-$851,236
														Subtotal = $5,922,322

Issue Date FY: 2023 ( Subtotal = $5,673,191 )
2023	2023	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	000	33	4/20/2023	EXTENSION WITH OR WITHOUT FUNDS	$5,673,191
														Subtotal = $5,673,191

Issue Date FY: 2022 ( Subtotal = $5,798,129 )
2022	2022	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	000	32	4/19/2022	NON-COMPETING CONTINUATION	$5,673,191
2022	2022	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	002	32	7/13/2022	NON-COMPETING CONTINUATION	$0
2022	2022	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	001	32	5/16/2022	SUPPLEMENT FOR EXPANSION	$124,938
														Subtotal = $5,798,129

Issue Date FY: 2021 ( Subtotal = $5,745,641 )
2021	2021	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	002	31	3/31/2021	NON-COMPETING CONTINUATION	$5,673,191
2021	2021	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	003	31	4/1/2021	SUPPLEMENT FOR EXPANSION	$72,450
2021	2021	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	004	31	7/16/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	001	30	2/10/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	000	30	11/18/2020	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $5,745,641

Issue Date FY: 2020 ( Subtotal = $6,413,107 )
2020	2020	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	002	30	9/18/2020	SUPPLEMENT FOR EXPANSION	$148,465
2020	2020	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	004	30	9/23/2020	SUPPLEMENT FOR EXPANSION	$404,835
2020	2020	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	003	30	9/21/2020	SUPPLEMENT FOR EXPANSION	$149,054
2020	2020	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	001	30	9/1/2020	SUPPLEMENT FOR EXPANSION	$46,371
2020	2020	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	000	30	3/31/2020	NON-COMPETING CONTINUATION	$5,664,382
														Subtotal = $6,413,107

Issue Date FY: 2019 ( Subtotal = $5,756,154 )
2019	2019	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	002	29	3/29/2019	NON-COMPETING CONTINUATION	$5,493,535
2019	2019	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	003	29	4/2/2019	SUPPLEMENT FOR EXPANSION	$104,158
2019	2019	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	005	29	8/28/2019	SUPPLEMENT FOR EXPANSION	$158,461
2019	2018	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	004	28	6/3/2019	SUPPLEMENT FOR EXPANSION	$0
2019	2018	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	001	28	11/1/2018	COMPETING CONTINUATION	$35,375
2019	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	000	27	11/1/2018	SUPPLEMENT FOR EXPANSION	-$35,375
														Subtotal = $5,756,154

Issue Date FY: 2018 ( Subtotal = $5,935,919 )
2018	2018	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	006	28	8/27/2018	SUPPLEMENT FOR EXPANSION	$249,965
2018	2018	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	004	28	8/20/2018	COMPETING CONTINUATION	$346,487
2018	2018	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	007	28	9/18/2018	SUPPLEMENT FOR EXPANSION	$48,000
2018	2018	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	001	28	7/25/2018	COMPETING CONTINUATION	$696,109
2018	2018	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	000	28	5/10/2018	COMPETING CONTINUATION	$4,941,845
2018	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	005	27	8/20/2018	SUPPLEMENT FOR EXPANSION	-$145,821
2018	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	003	27	8/20/2018	SUPPLEMENT FOR EXPANSION	-$200,000
2018	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	002	27	8/20/2018	SUPPLEMENT FOR EXPANSION	-$666
														Subtotal = $5,935,919

Issue Date FY: 2017 ( Subtotal = $5,420,211 ) (Continued on the next page)
2017	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	009	27	5/22/2017	SUPPLEMENT FOR EXPANSION	$118,875
2017	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	008	27	5/5/2017	NON-COMPETING CONTINUATION	$4,405,964
2017	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	011	27	5/25/2017	SUPPLEMENT FOR EXPANSION	$60,000
2017	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	012	27	5/26/2017	SUPPLEMENT FOR EXPANSION	$200,000
2017	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	010	27	5/24/2017	NON-COMPETING CONTINUATION	$489,551
2017	2017	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	013	27	9/20/2017	SUPPLEMENT FOR EXPANSION	$145,821
2017	2016	CASE WESTERN RESERVE UNIVERSITY	10900 EUCLID AVE	CLEVELAND	OH	44106	CUYAHOGA	USA	Cancer Centers Support Grants	006	26	4/21/2017	EXTENSION WITH OR WITHOUT FUNDS	$37,026
Grand Total All Awards = $134,200,184

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Case Comprehensive Cancer Center Support Grant

Award Number: P30CA043703

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/01/1997

PERIOD OF PERFORMANCE END DATE: 05/31/2030

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