Saturday, November 23, 2024 11/23/2024

Cancer Center Support Grant (CCSG)

Award Number: P30CA030199
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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ABSTRACT – OVERALL Sanford Burnham Prebys Medical Discovery Institute (SBP) is an independent nonprofit research and graduate degree-granting institution located in La Jolla, CA, that conducts laboratory-based biomedical research funded primarily through NIH grants. The mission of the SBP NCI-designated Cancer Center is to be a national leader in the effort to overcome cancer as a cause of human suffering and death. Our vision is to make paradigm- shifting discoveries that will underlie novel therapeutic modalities by creating, translating, and disseminating exceptional basic cancer science. We will attain this by: (1) conducting state-of-the-art, multidisciplinary basic research into the causes, prevention, and treatment of cancer; (2) advancing our discoveries into early preclinical development for the benefit of cancer patients everywhere; and (3) educating and training the next generation of cancer scientists. The CCSG proposal details our plans for advancing our early translational cancer research capabilities, including basic cancer discovery (novel gene targets and mechanisms), an area of long-standing exceptional strength at the Center. We will advance our scientific discoveries through several platforms, including small molecule-based drug discovery, an area in which we have significant technical capabilities and experience; and early preclinical therapeutic development, a growing strength. The Cancer Center is organized around three programs that encompass the cancer continuum: Tumor Initiation and Maintenance, Cancer Metabolism and Signaling Networks, and Tumor Microenvironment and Cancer Immunology, each having three sub-themes based on the hallmarks of cancer. We describe 10 Shared Resources that are critical for achieving the scientific goals of the programs with which they are tightly interwoven. We describe the past use of CCSG developmental funds for supporting the recruitment of new faculty and collaborative translational pilot projects. The San Diego NCI Cancer Center Council (C3) is a collaborative initiative between the three local NCI-designated Cancer Centers: SBP, UCSD, and the Salk Institute. The C3 initiative leverages the unique skills and resources of each cancer center for the treatment and ultimate cure of cancer by providing access to select shared resources at each institution at internal member rates, and outside philanthropic support for collaborative translational grants between investigators at the three cancer centers. The proposal highlights the progress made towards achieving our vision through multilevel strategic planning and evaluation, investments, recruitments, collaborations, organizational changes, and research accomplishments. Situated in San Diego, the fifth most populous county and the largest biotech and second largest life sciences cluster in the US, the Cancer Center is poised to achieve its vision by leveraging its scientific strengths through collaborations with academic and private sector investigators locally, nationally, and internationally.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $4,081,820 )
2024	2024	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 N TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	43	5/20/2024	NON-COMPETING CONTINUATION	$4,081,820
2024	2024	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 N TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	43	9/24/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,081,820

Issue Date FY: 2023 ( Subtotal = $4,581,820 )
2023	2023	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 N TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	42	9/18/2023	SUPPLEMENT FOR EXPANSION	$500,000
2023	2023	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 N TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	42	6/7/2023	NON-COMPETING CONTINUATION	$4,081,820
														Subtotal = $4,581,820

Issue Date FY: 2022 ( Subtotal = $4,081,820 )
2022	2022	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	41	8/18/2022	NON-COMPETING CONTINUATION	$4,081,820
														Subtotal = $4,081,820

Issue Date FY: 2021 ( Subtotal = $4,081,820 )
2021	2021	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	005	40	4/30/2021	NON-COMPETING CONTINUATION	$4,081,820
2021	2020	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	004	39	1/18/2021	COMPETING CONTINUATION	$0
2021	2020	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	003	39	10/22/2020	COMPETING CONTINUATION	$518,199
2021	2019	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	002	38	10/22/2020	SUPPLEMENT FOR EXPANSION	-$187,734
2021	2019	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	38	10/22/2020	NON-COMPETING CONTINUATION	-$184,215
2021	2019	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	38	10/22/2020	SUPPLEMENT FOR EXPANSION	-$146,250
														Subtotal = $4,081,820

Issue Date FY: 2020 ( Subtotal = $4,669,320 )
2020	2020	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	39	8/18/2020	SUPPLEMENT FOR EXPANSION	$487,500
2020	2020	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	39	5/29/2020	COMPETING CONTINUATION	$4,081,820
2020	2020	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	002	39	9/16/2020	SUPPLEMENT FOR EXPANSION	$100,000
														Subtotal = $4,669,320

Issue Date FY: 2019 ( Subtotal = $4,221,432 )
2019	2019	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	002	38	5/2/2019	SUPPLEMENT FOR EXPANSION	$187,734
2019	2019	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	38	5/1/2019	SUPPLEMENT FOR EXPANSION	$146,250
2019	2019	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	38	4/30/2019	NON-COMPETING CONTINUATION	$3,887,448
														Subtotal = $4,221,432

Issue Date FY: 2018 ( Subtotal = $4,232,742 )
2018	2018	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	37	4/24/2018	NON-COMPETING CONTINUATION	$3,887,448
2018	2018	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	002	37	8/7/2018	SUPPLEMENT FOR EXPANSION	$199,044
2018	2018	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	37	6/13/2018	SUPPLEMENT FOR EXPANSION	$146,250
														Subtotal = $4,232,742

Issue Date FY: 2017 ( Subtotal = $4,019,073 )
2017	2017	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	003	36	6/15/2017	NON-COMPETING CONTINUATION	-$146,250
2017	2017	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	36	5/1/2017	SUPPLEMENT FOR EXPANSION	$131,625
2017	2017	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	36	4/28/2017	NON-COMPETING CONTINUATION	$3,498,702
2017	2017	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	10901 NORTH TORREY PINES RD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	002	36	6/7/2017	NON-COMPETING CONTINUATION	$534,996
														Subtotal = $4,019,073

Issue Date FY: 2016 ( Subtotal = $4,033,698 )
2016	2016	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	35	5/2/2016	NON-COMPETING CONTINUATION	$3,887,448
2016	2016	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	35	5/11/2016	SUPPLEMENT FOR EXPANSION	$146,250
														Subtotal = $4,033,698

Issue Date FY: 2015 ( Subtotal = $4,012,638 )
2015	2015	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	34	9/1/2015	SUPPLEMENT FOR EXPANSION	$125,190
2015	2015	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	34	7/29/2015	COMPETING CONTINUATION	$3,887,448
														Subtotal = $4,012,638

Issue Date FY: 2014 ( Subtotal = $3,990,822 )
2014	2014	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	33	6/5/2014	NON-COMPETING CONTINUATION	$3,848,959
2014	2014	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	33	6/6/2014	SUPPLEMENT FOR EXPANSION	$141,863
														Subtotal = $3,990,822

Issue Date FY: 2013 ( Subtotal = $3,846,825 )
2013	2013	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	002	32	8/1/2013	NON-COMPETING CONTINUATION	$2,782,559
2013	2013	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	32	6/3/2013	NON-COMPETING CONTINUATION	$927,522
2013	2013	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	32	6/6/2013	SUPPLEMENT FOR EXPANSION	$136,744
														Subtotal = $3,846,825

Issue Date FY: 2012 ( Subtotal = $4,029,516 )
2012	2012	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	001	31	7/3/2012	SUPPLEMENT FOR EXPANSION	$142,912
2012	2012	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	000	31	5/24/2012	NON-COMPETING CONTINUATION	$3,886,604
														Subtotal = $4,029,516

Issue Date FY: 2011 ( Subtotal = $3,969,040 ) (Continued on the next page)
2011	2011	SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE	10901 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	SAN DIEGO	USA	Cancer Centers Support Grants	002	30	9/9/2011	SUPPLEMENT FOR EXPANSION	$82,436
Grand Total All Awards = $98,976,995

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Cancer Center Support Grant (CCSG)

Award Number: P30CA030199

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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