| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2024 ( Subtotal = $9,432,303 ) (Continued on the next page) |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI148668 | Characterizing the nuclear pore complex-T cell receptor connection | 000 | 5 | NIH | 11/15/2023 | $588,229 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG085498 | Novel Neuroprotective Roles for the Alzheimer's Disease Risk Gene SORLA in Tau Pathology and Pathogenesis | 000 | 1 | NIH | 11/22/2023 | $867,695 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | S10OD036254 | Beckman Coulter Biomek i7 Hybrid automated workstation | 000 | 1 | NIH | 3/26/2024 | $594,187 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R00NS120278 | Spatial Regulators of Skeletal Muscle Regeneration and Disease | 001 | 4 | NIH | 4/10/2024 | $17,412 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R00NS120278 | Spatial Regulators of Skeletal Muscle Regeneration and Disease | 000 | 4 | NIH | 3/1/2024 | $223,848 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA276193 | Discovery of Novel Inhibitors Targeting trans-Golgi Network Acidification in Pancreatic Cancer | 001 | 2 | NIH | 4/17/2024 | $32,253 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA276193 | Discovery of Novel Inhibitors Targeting trans-Golgi Network Acidification in Pancreatic Cancer | 000 | 2 | NIH | 2/28/2024 | $580,572 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL158677 | Regulation of Blood Glycoproteins by Lectin Receptors in Health and Disease | 000 | 2 | NIH | 3/29/2024 | $487,500 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA262746 | Molecular Pathogenesis of AF10-Rearranged Leukemias | 001 | 3 | NIH | 4/17/2024 | $22,480 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA262746 | Molecular Pathogenesis of AF10-Rearranged Leukemias | 000 | 3 | NIH | 3/13/2024 | $404,617 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG071694 | Preclinical discovery of novel farnesyltransferase inhibitors for the treatment of Alzheimer's disease and related tauopathies | 000 | 3 | NIH | 11/17/2023 | $790,358 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG072468 | Microglial heparan sulfate in the modulation of APOE function and neurodegeneration | 000 | 3 | NIH | 11/29/2023 | $522,864 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA269339 | Targeting ER+ Breast Cancer Through Induced Viral Mimicry | 000 | 3 | NIH | 3/26/2024 | $401,456 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA269339 | Targeting ER+ Breast Cancer Through Induced Viral Mimicry | 001 | 3 | NIH | 4/16/2024 | $22,304 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI167977 | Comparative resistomics of Gram-negative bacterial pathogens | 000 | 3 | NIH | 12/15/2023 | $660,151 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA266828 | Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancer | 001 | 3 | NIH | 4/17/2024 | $30,377 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA266828 | Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancer | 000 | 3 | NIH | 11/13/2023 | $546,821 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA267103 | Targeting the FBXO44/SUV39H1 Pathway in Cancer | 001 | 3 | NIH | 4/17/2024 | $22,304 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA267103 | Targeting the FBXO44/SUV39H1 Pathway in Cancer | 000 | 3 | NIH | 11/30/2023 | $401,456 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG071861 | Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventions | 000 | 4 | NIH | 2/2/2024 | $385,652 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI151371 | Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease | 000 | 4 | NIH | 1/11/2024 | $438,750 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01MH123826 | A Pharmacochaperone-based strategy for identifying chemical probes of brain-derived orphan GPCRs | 000 | 5 | NIH | 3/18/2024 | $706,566 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG065541 | Altered reverse transcriptase-dependent gene diversification mechanisms in Alzheimer's disease brains | 000 | 5 | NIH | 1/4/2024 | $836,735 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R00AG068303 | Epigenetic Reprogramming to Counteract Neuronal Aging and Degeneration | 000 | 3 | NIH | 1/26/2024 | $248,999 |
| | 2024 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK048247 | Glycosyltransferase Function in Development and Disease | 000 | 27 | NIH | 3/8/2024 | $438,750 |
| | 2024 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | U01DA057847 | Safety/Toxicology, ADME and CMC Activities to Support the Assessment of the mGlu2 PAM SBP-9330 in a Phase 2 Clinical Study in Smokers | 001 | 1 | NIH | 12/19/2023 | $0 |
| | 2024 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | U01DA057847 | Safety/Toxicology, ADME and CMC Activities to Support the Assessment of the mGlu2 PAM SBP-9330 in a Phase 2 Clinical Study in Smokers | 000 | 1 | NIH | 11/8/2023 | $0 |
| | 2024 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AA030888 | Optimization of Drug-like Properties of CRFBP-CRF2 Negative Allosteric Modulators for Alcohol Use Disorder | 000 | 1 | NIH | 11/7/2023 | $0 |
| | 2024 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R37CA270362 | Regulation of the tumor microenvironment by DNA damage repair proteins | 000 | 1 | NIH | 2/1/2024 | -$185,115 |
| | 2024 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | F99CA274682 | The role of the CCR4-NOT complex in the regulation of Nuclear Pore Complex assembly | 000 | 2 | NIH | 3/19/2024 | $0 |
| | 2024 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | U54AG079758 | Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics | 000 | 2 | NIH | 2/28/2024 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK099551 | New Congenital Disorders of Glycosylation: Therapy and Models | 000 | 9 | NIH | 4/15/2024 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | S10OD032325 | Cytek Aurora Full Spectrum Flow Cytometer | 000 | 1 | NIH | 2/5/2024 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DA056828 | Brain-penetrant GPR88 agonists as novel therapeutics for opioid abuse | 000 | 1 | NIH | 11/23/2023 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R33NS116191 | Optimization and Characterization of "MYC Degraders" for Pediatric Medulloblastoma | 000 | 2 | NIH | 1/22/2024 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21CA249822 | Multi-strain, live biotherapeutics as adjuncts to checkpoint inhibitor therapy | 000 | 2 | NIH | 1/16/2024 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R35NS122339 | Identifying and Targeting the Drivers of Pediatric Brain Tumors | 000 | 2 | NIH | 2/28/2024 | -$292,645 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21AG070676 | Characterizing a potential role for TREM2 in modulating tau pathogenesis in response to Abeta | 000 | 2 | NIH | 2/20/2024 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R03CA252144 | Targeting Checkpoint Inhibition in Anti-Tumor Responses | 000 | 2 | NIH | 1/16/2024 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21NS120075 | Transcriptional activation of LAMC1 as a resistance mechanism in recurrent PFA Ependymoma | 002 | 3 | NIH | 12/8/2023 | $615 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21NS120075 | Transcriptional activation of LAMC1 as a resistance mechanism in recurrent PFA Ependymoma | 000 | 3 | NIH | 12/4/2023 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK124583 | The extrahepatopancreatic ducts as a novel source of hepatic progenitors | 000 | 3 | NIH | 2/26/2024 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK117133 | The Development of TGR5 Antagonists for the Treatment of Cholangiopathies | 000 | 4 | NIH | 1/24/2024 | -$233 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01GM132292 | Control of gene expression in neural stem cells by crosstalk between messenger RNA methylation and histone modification | 000 | 4 | NIH | 3/6/2024 | -$4,253 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01GM134712 | MYOD Regulation of 3D Chromatin Structure | 000 | 4 | NIH | 12/21/2023 | $0 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL148827 | Discovery of small molecule promoters of cardiomyocyte proliferation to restore cardiac performance in disease | 001 | 4 | NIH | 3/6/2024 | -$66 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL148827 | Discovery of small molecule promoters of cardiomyocyte proliferation to restore cardiac performance in disease | 000 | 4 | NIH | 3/6/2024 | -$8,148 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL141880 | Mechanisms of hematopoietic acute radiation syndrome induction and radioprotection through sphingosine 1-phosphate receptor 1 signal modulation | 000 | 5 | NIH | 3/28/2024 | -$4,389 |
| | 2024 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | T32AI125209 | Frontiers in Fundamental and Translational Immunology | 001 | 5 | NIH | 2/21/2024 | -$149,305 |
|
