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 | Issue Date FY: 2026 ( Subtotal = $49,804,153 ) (Continued on the next page) |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DA056828 | Brain-penetrant GPR88 agonists as novel therapeutics for opioid abuse | 001 | 3 | NIH | 7/31/2026 | $581,970 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | F31HL189275 | ETS Transcription Factors as Cardiac Maintenance Regulators: Linking Raf-ERK-Pnt Signaling to Adult Cardiac Hypertrophy | 000 | 1 | NIH | 9/4/2026 | $38,314 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK145938 | Post-transcriptional regulation by RNA binding proteins in liver fibrosis | 000 | 1 | NIH | 8/10/2026 | $910,940 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG070391 | Elucidating a microgliaassociated role for SORLA in modulating AD pathogenesis | 000 | 3 | NIH | 7/20/2026 | $865,606 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL178767 | Single-Construct Gene Therapy For Enhanced Heart Repair | 000 | 1 | NIH | 6/30/2026 | $1,603,648 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | F31CA318249 | Role of P2X4 Receptors in Golgi pH Regulation in Pancreatic Cancer | 001 | 1 | NIH | 8/18/2026 | $0 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | F31CA318249 | Role of P2X4 Receptors in Golgi pH Regulation in Pancreatic Cancer | 000 | 1 | NIH | 8/18/2026 | $46,714 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | UG3NS141745 | Neurotensin 1 allosteric modulator for the treatment of pain | 000 | 1 | NIH | 4/17/2026 | $3,855,681 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01GM166538 | Molecular Basis of Nuclear Pore Formation | 000 | 1 | NIH | 8/19/2026 | $2,903,176 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01GM159006 | Catalytic mechanisms, regulation, and anti-fibrotic roles of the TMEM2 cell surface hyaluronidase | 000 | 1 | NIH | 3/31/2026 | $1,677,007 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | S10OD040289 | Spectral Cell Sorter | 000 | 1 | NIH | 6/19/2026 | $632,112 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | S10OD040289 | Spectral Cell Sorter | 000 | 1 | NIH | 6/19/2026 | $1 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA308029 | Characterizing the functions of Nup210 in leukemia | 000 | 1 | NIH | 7/28/2026 | $803,681 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21TR006419 | Targeting GATA3 as a therapeutic strategy in Th2-driven diseases | 000 | 1 | NIH | 7/21/2026 | $536,250 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21TR006419 | Targeting GATA3 as a therapeutic strategy in Th2-driven diseases | 001 | 1 | NIH | 9/2/2026 | $536,250 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21TR006419 | Targeting GATA3 as a therapeutic strategy in Th2-driven diseases | 001 | 1 | NIH | 9/2/2026 | -$536,250 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | P30CA030199 | Cancer Center Support Grant (CCSG) | 002 | 45 | NIH | 5/5/2026 | $4,081,820 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA296261 | Transcriptional reprogramming of anti-tumor immunity | 000 | 1 | NIH | 7/14/2026 | $646,134 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | U54AG079758 | Spatial Mapping Senescent Cells Across the Mouse Lifespan by Multiplex Transcriptomics and Epigenomics | 001 | 4 | NIH | 8/27/2026 | $630,884 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA276193 | Discovery of Novel Inhibitors Targeting trans-Golgi Network Acidification in Pancreatic Cancer | 000 | 4 | NIH | 3/2/2026 | $645,540 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK133930 | Ubiquitin D as a potential therapeutic target for NASH, HCC and chronic kidney diseases | 000 | 4 | NIH | 6/18/2026 | $500,000 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21CA293150 | Immune Checkpoint Blockade Targeting the Novel PSGL-1/VISTA Axis for Pancreatic Cancer | 000 | 2 | NIH | 2/26/2026 | $209,674 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK137061 | Dissecting the Intracellular and Extracellular Role of TREM2 in the Pathogenesis of Non-Alcoholic Steatohepatitis. | 000 | 4 | NIH | 6/26/2026 | $664,854 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA262794 | EPHA2 Receptor Signaling in Breast Cancer Mechanotransduction | 001 | 5 | NIH | 7/3/2026 | $88,084 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA262794 | EPHA2 Receptor Signaling in Breast Cancer Mechanotransduction | 000 | 5 | NIH | 6/19/2026 | $535,848 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG085498 | Novel Neuroprotective Roles for the Alzheimer's Disease Risk Gene SORLA in Tau Pathology and Pathogenesis | 001 | 3 | NIH | 2/26/2026 | $87,745 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG085498 | Novel Neuroprotective Roles for the Alzheimer's Disease Risk Gene SORLA in Tau Pathology and Pathogenesis | 000 | 3 | NIH | 12/22/2025 | $789,700 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | P01CA281819 | Role of hypernutrition and metabolic stress in non-alcoholic steatohepatitis (NASH) driven hepatocellular carcinoma (HCC) | 000 | 3 | NIH | 8/11/2026 | $2,272,153 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | U01CA274295 | Regulation of PDAC metabolism and immunity by collagen and its cleavage products | 001 | 5 | NIH | 9/3/2026 | $1,021,269 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R00AG068303 | Epigenetic Reprogramming to Counteract Neuronal Aging and Degeneration | 001 | 5 | NIH | 3/9/2026 | $24,899 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R00AG068303 | Epigenetic Reprogramming to Counteract Neuronal Aging and Degeneration | 000 | 5 | NIH | 2/12/2026 | $224,100 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA272433 | Macropinocytosis Inhibition as a Glutamine Mimetic Sensitization Strategy in Pancreatic Cancer | 000 | 3 | NIH | 7/1/2026 | $565,933 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA286431 | Discovery of Potent Selective Inhibitors of the Histone Methyltransferase SUV39H1 for the Treatment of Cancer | 000 | 3 | NIH | 7/22/2026 | $809,234 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA267103 | Targeting the FBXO44/SUV39H1 Pathway in Cancer | 001 | 5 | NIH | 4/16/2026 | $44,607 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA267103 | Targeting the FBXO44/SUV39H1 Pathway in Cancer | 000 | 5 | NIH | 12/5/2025 | $401,456 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI167977 | Comparative resistomics of Gram-negative bacterial pathogens | 000 | 5 | NIH | 1/6/2026 | $733,500 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL158677 | Regulation of Blood Glycoproteins by Lectin Receptors in Health and Disease | 000 | 4 | NIH | 3/9/2026 | $487,500 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG083373 | Hormetic regulation of autophagy in aging | 000 | 3 | NIH | 6/19/2026 | $586,599 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA285997 | Collagen fibers and fragments regulate pancreatic cancer metabolism and growth | 003 | 4 | NIH | 2/27/2026 | $809,870 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R37AI043477 | NF-kappaB and Mitochondrial Signals as Positive and Negative Regulators of Inflammation | 007 | 30 | NIH | 5/26/2026 | $741,246 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AR056712 | Pathogenic Alterations of the 3D Epigenetic Landscape in Dystrophin-Deficient Skeletal Muscles and Reversal by Dystrophin Re-Expression | 000 | 15 | NIH | 7/3/2026 | $581,203 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AA030888 | Optimization of Drug-like Properties of CRFBP-CRF2 Negative Allosteric Modulators for Alcohol Use Disorder | 000 | 4 | NIH | 8/19/2026 | $771,544 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG086914 | Discovery and optimization of ApoE4 correctors for the treatment of Alzheimer's Disease | 001 | 3 | NIH | 7/24/2026 | $2,676,401 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL166256 | Metabolic Reprogramming of the Adult heart to a Regenerative State | 001 | 4 | NIH | 3/26/2026 | $517,727 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01NS132780 | Investigation of ecDNA as a Driver of Intratumoral Heterogeneity and Treatment Resistance in High-Risk Medulloblastoma | 000 | 4 | NIH | 8/28/2026 | $636,772 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK132689 | Improving Proinsulin Folding to Ameliorate Type II Diabetes | 000 | 4 | NIH | 5/4/2026 | $760,498 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R50CA283813 | Development and Implementation of Advanced Technologies for Cancer Metabolism Research | 000 | 4 | NIH | 8/17/2026 | $142,032 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK133448 | The NRF2-FBP1 crossregulatory loop and the control of healthy and diseased liver metabolism | 008 | 6 | NIH | 5/25/2026 | $747,010 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R35GM147487 | Molecular mechanisms underlying the assembly of the human proteasome and endogenous protein complexes | 000 | 5 | NIH | 7/15/2026 | $487,500 |
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