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 | Issue Date FY: 2023 ( Subtotal = $8,053,125 ) |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL149992 | Genetic Pathways in Ceramide-Associated Lipotoxic Cardiomyopathy and Heart Failure | 000 | 4 | NIH | 11/16/2022 | $438,750 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI167977 | Comparative resistomics of Gram-negative bacterial pathogens | 000 | 2 | NIH | 12/6/2022 | $733,500 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA267103 | Targeting the FBXO44/SUV39H1 Pathway in Cancer | 000 | 2 | NIH | 1/30/2023 | $437,141 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG062557 | Targeting neuroinflammation in AD with novel CX3CR1 agonists | 000 | 5 | NIH | 2/24/2023 | $554,644 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA266828 | Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancer | 000 | 2 | NIH | 3/2/2023 | $599,074 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG062190 | "A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways" | 000 | 5 | NIH | 1/11/2023 | $974,957 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG071861 | Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventions | 000 | 3 | NIH | 3/6/2023 | $393,372 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK048247 | Glycosyltransferase Function in Development and Disease | 002 | 26 | NIH | 3/18/2023 | $487,500 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | F32HL156607 | Identifying novel networks of candidate Atrial Fibrillation genes in the Drosophila cardiac aging model | 000 | 3 | NIH | 3/17/2023 | $76,052 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI151371 | Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease | 000 | 3 | NIH | 3/13/2023 | $487,500 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI151371 | Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease | 001 | 3 | NIH | 3/23/2023 | $0 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA276193 | Discovery of Novel Inhibitors Targeting trans-Golgi Network Acidification in Pancreatic Cancer | 000 | 1 | NIH | 3/22/2023 | $647,398 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL158677 | Regulation of Blood Glycoproteins by Lectin Receptors in Health and Disease | 000 | 1 | NIH | 3/13/2023 | $487,500 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21AG075483 | Novel Strategy to Quantitate Delayed Aging by Caloric Restriction | 000 | 2 | NIH | 2/3/2023 | $250,212 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG065541 | Altered reverse transcriptase-dependent gene diversification mechanisms in Alzheimer's disease brains | 000 | 4 | NIH | 1/26/2023 | $929,705 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA262746 | Molecular Pathogenesis of AF10-Rearranged Leukemias | 000 | 2 | NIH | 3/23/2023 | $441,618 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG065541 | Altered reverse transcriptase-dependent gene diversification mechanisms in Alzheimer's disease brains | 001 | 4 | NIH | 1/27/2023 | $83,809 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG062617 | Discovery of Selective Inhibitors for the EphA4 Kinase | 000 | 4 | NIH | 1/27/2023 | $760,964 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R61HL161804 | Optimization of fibroblast-selective inhibitors of YAP/TAZ as novel therapeutics for Pulmonary Fibrosis | 000 | 2 | NIH | 1/19/2023 | $584,310 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21DE031889 | Exploratory Therapy for the Skeletal/Dental Phenotype in PHOSPHO1 Deficiency | 000 | 2 | NIH | 2/16/2023 | $241,306 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI148668 | Characterizing the nuclear pore complex-T cell receptor connection | 000 | 4 | NIH | 11/15/2022 | $653,587 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG072468 | Microglial heparan sulfate in the modulation of APOE function and neurodegeneration | 000 | 2 | NIH | 1/5/2023 | $580,960 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG071694 | Preclinical discovery of novel farnesyltransferase inhibitors for the treatment of Alzheimer's disease and related tauopathies | 000 | 2 | NIH | 1/31/2023 | $894,645 |
| | 2023 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL149992 | Genetic Pathways in Ceramide-Associated Lipotoxic Cardiomyopathy and Heart Failure | 001 | 4 | NIH | 2/11/2023 | $48,750 |
| | 2023 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL148827 | Discovery of small molecule promoters of cardiomyocyte proliferation to restore cardiac performance in disease | 000 | 4 | NIH | 12/2/2022 | -$41,024 |
| | 2023 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK048247 | Glycosyltransferase Function in Development and Disease | 001 | 25 | NIH | 3/17/2023 | $190,518 |
| | 2023 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21NS130137 | Transcriptional activation of RCOR2 as a novel oncogenic mechanism in supratentorial ependymoma | 001 | 2 | NIH | 2/20/2023 | $536,250 |
| | 2023 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21NS120075 | Transcriptional activation of LAMC1 as a resistance mechanism in recurrent PFA Ependymoma | 001 | 3 | NIH | 2/17/2023 | $195,948 |
| | 2023 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | U01DA051077 | Clinical development of an mGlu2 positive allosteric modulator to treat nicotine addiction | 000 | 3 | NIH | 11/10/2022 | $0 |
| | 2023 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | RF1AG070391 | Elucidating a microgliaassociated role for SORLA in modulating AD pathogenesis | 000 | 1 | NIH | 3/16/2023 | $0 |
| | 2023 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | U54AG079758 | Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics | 000 | 1 | NIH | 2/7/2023 | $0 |
| | 2023 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R33NS116191 | Optimization and Characterization of "MYC Degraders" for Pediatric Medulloblastoma | 000 | 2 | NIH | 3/28/2023 | $0 |
| | 2023 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21DE031889 | Exploratory Therapy for the Skeletal/Dental Phenotype in PHOSPHO1 Deficiency | 001 | 1 | NIH | 2/21/2023 | $0 |
| | 2023 | 2021 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | UM1AI164561 | Reversing Immune Dysfunction for HIV-1 Eradication | 000 | 1 | NIH | 10/12/2022 | -$4,476,454 |
| | 2023 | 2021 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK048247 | Glycosyltransferase Function in Development and Disease | 000 | 24 | NIH | 3/17/2023 | -$190,518 |
| | 2023 | 2021 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21AI154916 | Regulation of CD4+ T Cell Responses During Chronic Viral Infection | 001 | 2 | NIH | 12/13/2022 | $0 |
| | 2023 | 2021 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21AI154916 | Regulation of CD4+ T Cell Responses During Chronic Viral Infection | 000 | 2 | NIH | 12/13/2022 | $0 |
| | 2023 | 2021 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21NS116455 | Disruption of a DNA loop as a complementary mechanism of H3.3K27M mutations | 001 | 3 | NIH | 2/17/2023 | $51,221 |
| | 2023 | 2020 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R35GM118186 | Membrane protein effectors of pathogen interactions with host | 000 | 5 | NIH | 11/21/2022 | $0 |
| | 2023 | 2020 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01GM099040 | Caspases in Inflammatory Cell Death Networks | 000 | 8 | NIH | 1/9/2023 | -$70 |
| | 2023 | 2020 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | S10OD028716 | A 600 MHz NMR spectrometer upgrade for the Sanford Burnham Prebys Cancer Center | 000 | 1 | NIH | 11/9/2022 | $0 |
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| Issue Date FY: 2022 ( Subtotal = $63,474,761 ) (Continued on the next page) |
| | 2022 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | RF1AG070391 | Elucidating a microgliaassociated role for SORLA in modulating AD pathogenesis | 000 | 1 | NIH | 7/21/2022 | $2,818,493 |
| | 2022 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R35GM147487 | Molecular mechanisms underlying the assembly of the human proteasome and endogenous protein complexes | 000 | 1 | NIH | 7/22/2022 | $487,500 |
| | 2022 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21AG075446 | Epigenetic drift of the Aging Heart in Drosophila | 000 | 1 | NIH | 7/27/2022 | $292,500 |
| | 2022 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA262746 | Molecular Pathogenesis of AF10-Rearranged Leukemias | 000 | 1 | NIH | 4/12/2022 | $449,812 |
| | 2022 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA269339 | Targeting ER+ Breast Cancer Through Induced Viral Mimicry | 000 | 1 | NIH | 2/23/2022 | $441,716 |
| | 2022 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA262794 | EPHA2 Receptor Signaling in Breast Cancer Mechanotransduction | 000 | 1 | NIH | 4/14/2022 | $551,618 |
| | 2022 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 NORTH TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R61HL161804 | Optimization of fibroblast-selective inhibitors of YAP/TAZ as novel therapeutics for Pulmonary Fibrosis | 001 | 1 | NIH | 8/5/2022 | -$643,499 |
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