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 | Issue Date FY: 2026 ( Subtotal = $6,673,134 ) |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG072468 | Microglial heparan sulfate in the modulation of APOE function and neurodegeneration | 001 | 5 | NIH | 2/23/2026 | $58,096 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG085498 | Novel Neuroprotective Roles for the Alzheimer's Disease Risk Gene SORLA in Tau Pathology and Pathogenesis | 001 | 3 | NIH | 2/26/2026 | $87,745 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL158677 | Regulation of Blood Glycoproteins by Lectin Receptors in Health and Disease | 000 | 4 | NIH | 3/9/2026 | $487,500 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21CA293150 | Immune Checkpoint Blockade Targeting the Novel PSGL-1/VISTA Axis for Pancreatic Cancer | 000 | 2 | NIH | 2/26/2026 | $209,674 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA285997 | Collagen fibers and fragments regulate pancreatic cancer metabolism and growth | 003 | 4 | NIH | 2/27/2026 | $809,870 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA276193 | Discovery of Novel Inhibitors Targeting trans-Golgi Network Acidification in Pancreatic Cancer | 000 | 4 | NIH | 3/2/2026 | $645,540 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R00AG068303 | Epigenetic Reprogramming to Counteract Neuronal Aging and Degeneration | 001 | 5 | NIH | 3/9/2026 | $24,899 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG085498 | Novel Neuroprotective Roles for the Alzheimer's Disease Risk Gene SORLA in Tau Pathology and Pathogenesis | 000 | 3 | NIH | 12/22/2025 | $789,700 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI167977 | Comparative resistomics of Gram-negative bacterial pathogens | 000 | 5 | NIH | 1/6/2026 | $733,500 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R00AG068303 | Epigenetic Reprogramming to Counteract Neuronal Aging and Degeneration | 000 | 5 | NIH | 2/12/2026 | $224,100 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA267103 | Targeting the FBXO44/SUV39H1 Pathway in Cancer | 000 | 5 | NIH | 12/5/2025 | $401,456 |
| | 2026 | 2026 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG072468 | Microglial heparan sulfate in the modulation of APOE function and neurodegeneration | 000 | 5 | NIH | 12/10/2025 | $522,864 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | U01DA057847 | Safety/Toxicology, ADME and CMC Activities to Support the Assessment of the mGlu2 PAM SBP-9330 in a Phase 2 Clinical Study in Smokers | 000 | 3 | NIH | 1/21/2026 | $0 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | P30CA030199 | Administrative Supplement to Cancer Center Support Grant (CCSG) | 001 | 44 | NIH | 1/21/2026 | $0 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R37AI043477 | NF-kappaB and Mitochondrial Signals as Positive and Negative Regulators of Inflammation | 001 | 29 | NIH | 12/18/2025 | $389,397 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA285997 | Collagen fibers and fragments regulate pancreatic cancer metabolism and growth | 001 | 3 | NIH | 12/22/2025 | $532,713 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AG071861 | Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventions | 000 | 5 | NIH | 2/20/2026 | $0 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | P30CA030199 | Administrative Supplement to Cancer Center Support Grant (CCSG) | 000 | 44 | NIH | 1/20/2026 | $0 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI151371 | Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease | 000 | 5 | NIH | 3/3/2026 | $0 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK133448 | The NRF2-FBP1 crossregulatory loop and the control of healthy and diseased liver metabolism | 003 | 5 | NIH | 2/20/2026 | -$28,982 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA266828 | Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancer | 000 | 4 | NIH | 2/18/2026 | $0 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK120714 | Control of Lipogenesis and Hepatic Steatosis by Caspase-2 | 003 | 8 | NIH | 2/11/2026 | -$139,522 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK133448 | The NRF2-FBP1 crossregulatory loop and the control of healthy and diseased liver metabolism | 001 | 5 | NIH | 1/28/2026 | $537,674 |
| | 2026 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK120714 | Control of Lipogenesis and Hepatic Steatosis by Caspase-2 | 001 | 8 | NIH | 1/29/2026 | $393,221 |
| | 2026 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01HL054732 | Genetic Control of Cardiac Development: Congenital Heart Disease Gene Discovery in Drosophila | 000 | 27 | NIH | 12/30/2025 | $0 |
| | 2026 | 2024 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AI158552 | Overriding the Immune Evasion Tactics of Coronavirus | 000 | 4 | NIH | 2/4/2026 | -$6,096 |
| | 2026 | 2023 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | K99AG073450 | Mitonuclear signaling pathways in senescence-associated inflammation | 000 | 2 | NIH | 1/13/2026 | $0 |
| | 2026 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | RF1AG070391 | Elucidating a microgliaassociated role for SORLA in modulating AD pathogenesis | 000 | 1 | NIH | 1/22/2026 | $0 |
| | 2026 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | U01DA051077 | Clinical development of an mGlu2 positive allosteric modulator to treat nicotine addiction | 000 | 3 | NIH | 1/8/2026 | -$215 |
| | 2026 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DA056828 | Brain-penetrant GPR88 agonists as novel therapeutics for opioid abuse | 000 | 1 | NIH | 2/17/2026 | $0 |
| | 2026 | 2022 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R21NS130137 | Transcriptional activation of RCOR2 as a novel oncogenic mechanism in supratentorial ependymoma | 000 | 2 | NIH | 11/17/2025 | $0 |
|
| Issue Date FY: 2025 ( Subtotal = $42,222,578 ) (Continued on the next page) |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA286431 | Discovery of Potent Selective Inhibitors of the Histone Methyltransferase SUV39H1 for the Treatment of Cancer | 000 | 2 | NIH | 7/17/2025 | $809,248 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA267103 | Targeting the FBXO44/SUV39H1 Pathway in Cancer | 001 | 4 | NIH | 6/4/2025 | $44,607 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AA030888 | Optimization of Drug-like Properties of CRFBP-CRF2 Negative Allosteric Modulators for Alcohol Use Disorder | 000 | 3 | NIH | 8/18/2025 | $786,961 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AR056712 | Pathogenic Alterations of the 3D Epigenetic Landscape in Dystrophin-Deficient Skeletal Muscles and Reversal by Dystrophin Re-Expression | 000 | 14 | NIH | 7/1/2025 | $575,324 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK132689 | Improving Proinsulin Folding to Ameliorate Type II Diabetes | 001 | 3 | NIH | 8/29/2025 | $0 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK132689 | Improving Proinsulin Folding to Ameliorate Type II Diabetes | 000 | 3 | NIH | 4/29/2025 | $760,498 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R50CA283813 | Development and Implementation of Advanced Technologies for Cancer Metabolism Research | 000 | 3 | NIH | 7/17/2025 | $142,032 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R35GM147487 | Molecular mechanisms underlying the assembly of the human proteasome and endogenous protein complexes | 000 | 4 | NIH | 7/29/2025 | $487,500 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA266828 | Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancer | 001 | 4 | NIH | 6/4/2025 | $53,887 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01CA266828 | Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancer | 000 | 4 | NIH | 11/6/2024 | $485,003 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01GM143583 | Function and Mechanism of the Hippo-PI5P4K Axis for Growth Control | 000 | 4 | NIH | 6/17/2025 | $555,975 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01AR077448 | Role of Fbxw7-Mediated Proteasomal Degradation in Myofibers in Determining Muscle Stem Cell Pool Size | 000 | 5 | NIH | 7/11/2025 | $586,260 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | P01HL131474 | Protein Glycosylation in the Coagulopathy and Inflammation of Sepsis | 000 | 10 | NIH | 6/6/2025 | $2,674,150 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK099551 | New Congenital Disorders of Glycosylation: Therapy and Models | 000 | 11 | NIH | 7/17/2025 | $809,568 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01DK048247 | Glycosyltransferase Function in Development and Disease | 000 | 28 | NIH | 8/13/2025 | $487,500 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01GM131374 | Eph Receptor Heterointeractions in Signaling | 000 | 6 | NIH | 12/24/2024 | $27,399 |
| | 2025 | 2025 | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | 10901 N TORREY PINES RD | LA JOLLA | CA | 92037-1005 | SAN DIEGO | USA | R01GM131374 | Eph Receptor Heterointeractions in Signaling | 001 | 7 | NIH | 5/19/2025 | $480,649 |
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