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CANCER CENTER SUPPORT GRANT

Award Number: P30CA022453
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/08/1997
PERIOD OF PERFORMANCE END DATE: 11/30/2025

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CANCER CENTER SUPPORT GRANT - OVERALL - ABSTRACT The Karmanos Cancer Institute (KCI), founded in 1943, is a not-for-profit, cancer-only research and patient care organization in partnership with Wayne State University (WSU) in Michigan. The designation by the NCI as a Comprehensive Cancer Center was achieved in 1978. KCI operates its wholly-owned, free-standing, cancer hospital and ambulatory clinics (KCC) in Detroit and in Farmington Hills, a suburban location. As a member of McLaren Health Care (MHC), a not-for profit health care corporation, KCI is also responsible for cancer research, quality of care, and cancer care operations in all facilities owned and operated by MHC. Our catchment area covers 46 of Michigan’s 83 counties with a population of 6.7 million people. This catchment area is home to 95% of our patients, and KCI sees one-third of all new cancer patients in the catchment area. The Southeast region of our catchment area includes the metropolitan Detroit, defined as a tri-county area (Wayne, Oakland, Macomb) and home to 3.86 million residents. The city of Detroit is the largest city in the state (672,000 residents). Detroit is a resource-challenged area, with a median household income of $27,838 and 37.9% of residents living below poverty level, compared to 16.7% in the state of Michigan. The majority of census tracts in the city of Detroit are medically underserved areas based on HRSA definitions. About 79% of Detroit residents identify as African American, a group that disproportionately carries KCI catchment area’s cancer burden. In 2018, KCI physicians saw approximately 12,000 new cancer patients (including approximately 8,000 analytic cases), with approximately 15% representing minority groups. The annual number of new cancer cases in these 46 counties is approximately 39,000 and has not changed significantly since 2014. In FY19, our minority accrual to interventional treatment protocols was 24.2%. We have a long standing scientific and patient care commitment to the African American population of southeastern Michigan, as exemplified in the broad array of studies focused on molecular, therapeutic, and social disparities. This application profiles the strengths and successes of our four scientific Programs, Tumor Biology and Microenvironment (TBM, 01), Molecular Imaging (MI, 02), Molecular Therapeutics (MT, 03), and Population Studies and Disparities Research (PSDR, 04). The research efforts of these Programs is supported by nine Shared Resources (Cores), including one developing Core. As of December 2019, KCI’s 135 scientific members have secured total annual direct project funding of $ 63,162,159 (an increase of 12.3% from 2015) of which $21,864,688 is peer reviewed funding and $11,743,830 is from the NCI.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $2,368,190 )
2025	2025	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	000	43	12/3/2024	NON-COMPETING CONTINUATION	$2,368,190
														Subtotal = $2,368,190

Issue Date FY: 2024 ( Subtotal = $2,883,513 )
2024	2024	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	004	42	9/12/2024	SUPPLEMENT FOR EXPANSION	$198,452
2024	2024	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	003	42	4/17/2024	NON-COMPETING CONTINUATION	$268,507
2024	2024	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	000	42	12/1/2023	NON-COMPETING CONTINUATION	$2,416,554
2024	2023	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	001	41	2/28/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2023	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	002	41	3/7/2024	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $2,883,513

Issue Date FY: 2023 ( Subtotal = $2,935,558 )
2023	2023	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	000	41	12/28/2022	NON-COMPETING CONTINUATION	$2,660,558
2023	2023	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	001	41	1/9/2023	SUPPLEMENT FOR EXPANSION	$75,000
2023	2023	WAYNE STATE UNIVERSITY	5700 CASS AVE STE 4900	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	002	41	9/19/2023	SUPPLEMENT FOR EXPANSION	$200,000
														Subtotal = $2,935,558

Issue Date FY: 2022 ( Subtotal = $2,976,696 )
2022	2022	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	002	40	9/13/2022	SUPPLEMENT FOR EXPANSION	$115,000
2022	2022	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	000	40	1/20/2022	NON-COMPETING CONTINUATION	$2,751,779
2022	2022	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	004	40	9/14/2022	SUPPLEMENT FOR EXPANSION	$75,000
2022	2022	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	003	40	9/14/2022	NON-COMPETING CONTINUATION	-$115,000
2022	2022	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	005	40	9/15/2022	SUPPLEMENT FOR EXPANSION	$149,917
2022	2022	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	001	40	8/3/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,976,696

Issue Date FY: 2021 ( Subtotal = $3,003,675 )
2021	2021	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	001	39	5/13/2021	COMPETING CONTINUATION	$781,395
2021	2021	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	000	39	2/10/2021	COMPETING CONTINUATION	$2,613,676
2021	2021	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	005	39	9/22/2021	SUPPLEMENT FOR EXPANSION	$115,000
2021	2021	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	004	39	7/19/2021	SUPPLEMENT FOR EXPANSION	$125,000
2021	2021	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	006	39	9/23/2021	SUPPLEMENT FOR EXPANSION	$149,999
2021	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	002	38	5/13/2021	SUPPLEMENT FOR EXPANSION	-$151,395
2021	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	003	38	5/13/2021	SUPPLEMENT FOR EXPANSION	-$630,000
														Subtotal = $3,003,675

Issue Date FY: 2020 ( Subtotal = $3,643,344 )
2020	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	005	38	6/12/2020	SUPPLEMENT FOR EXPANSION	$154,000
2020	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	004	38	4/14/2020	SUPPLEMENT FOR EXPANSION	$115,000
2020	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	000	38	12/10/2019	NON-COMPETING CONTINUATION	$2,562,428
2020	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	002	38	1/24/2020	SUPPLEMENT FOR EXPANSION	$60,000
2020	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	38	1/13/2020	SUPPLEMENT FOR EXPANSION	$121,916
2020	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	006	38	7/22/2020	SUPPLEMENT FOR EXPANSION	$630,000
2020	2020	WAYNE STATE UNIVERSITY	5057 WOODWARD STE 13001	DETROIT	MI	48202	WAYNE	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	003	38	2/5/2020	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $3,643,344

Issue Date FY: 2019 ( Subtotal = $3,286,251 )
2019	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	004	37	5/15/2019	SUPPLEMENT FOR EXPANSION	$60,000
2019	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	002	37	12/13/2018	SUPPLEMENT FOR EXPANSION	$109,797
2019	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	000	37	12/10/2018	NON-COMPETING CONTINUATION	$2,562,428
2019	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	001	37	12/12/2018	SUPPLEMENT FOR EXPANSION	$251,380
2019	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	003	37	12/14/2018	SUPPLEMENT FOR EXPANSION	$243,613
2019	2019	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	005	37	7/31/2019	SUPPLEMENT FOR EXPANSION	$59,033
														Subtotal = $3,286,251

Issue Date FY: 2018 ( Subtotal = $3,309,450 ) (Continued on the next page)
2018	2018	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	000	36	11/28/2017	NON-COMPETING CONTINUATION	$2,306,185
2018	2018	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	004	36	5/28/2018	NON-COMPETING CONTINUATION	$256,243
2018	2018	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	008	36	8/27/2018	SUPPLEMENT FOR EXPANSION	$127,646
2018	2018	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	006	36	6/8/2018	SUPPLEMENT FOR EXPANSION	$351,933
2018	2018	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	005	36	6/4/2018	SUPPLEMENT FOR EXPANSION	$13,126
2018	2018	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	001	36	1/8/2018	SUPPLEMENT FOR EXPANSION	$118,124
2018	2018	WAYNE STATE UNIVERSITY	5057 WOODWARD 13 FLOOR	DETROIT	MI	48202	WAYNE	USA	Cancer Centers Support Grants	009	36	8/30/2018	SUPPLEMENT FOR EXPANSION	$46,200
Grand Total All Awards = $63,945,316

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CANCER CENTER SUPPORT GRANT

Award Number: P30CA022453

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/08/1997

PERIOD OF PERFORMANCE END DATE: 11/30/2025

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