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Cancer Center Support Grant

Award Number: P30CA014599
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/1997
PERIOD OF PERFORMANCE END DATE: 03/31/2029

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Cancer Center Support Grant - PROJECT SUMMARY/ABSTRACT - OVERALL The University of Chicago Medicine Comprehensive Cancer Center (UCCCC) is submitting this competing renewal application for its Cancer Center Support Grant for Years 49-54. The mission of UCCCC is “to eradicate cancer through equitable prevention, innovative and collaborative research, compassionate patient care, inclusive education and dedicated community engagement”. Upon arrival in March 2021 as the new Director, Kunle Odunsi, MD, PhD provided a vision for the Center that focuses on translation of science into the forefront of UCCCC’s overall mission. To accomplish this, a new Strategic Plan was launched to guide UCCCC towards its vision to be a “global center of excellence for inclusive and equitable cancer care, research and discovery dedicated to cancer eradication”. The plan is organized around the cross-cutting themes of bidirectional translational cancer science between the domains of the laboratory, the clinic, and the community; transdisciplinary research programs; and transformation of the cancer burden in the catchment area (CA) and beyond. The 193 members of the UCCCC are organized into 4 Research Programs: Immunology and Cancer, Clinical and Experimental Therapeutics, Molecular Mechanisms of Cancer, and Cancer Prevention and Control. They are supported by 10 Shared Resources and 18 multidisciplinary Disease Teams. Notable accomplishments during this funding cycle (2018-2022) include: (1) Restructuring leadership by creating two new AD positions (Diversity, Equity and Inclusion [DEI], and Shared Resources); (2) Recruiting 68 talented researchers (45 new to the University of Chicago); (3) establishing a new Office for DEI; (4) bolstering the Offices for Community Outreach and Engagement, Cancer Research Training and Education, Clinical Protocol and Data Management, and Protocol Review and Monitoring Systems; (5) publishing 3,108 scientific articles 35% of which in high-impact (≥10) journals; (6) securing $55.4M peer-reviewed funding, with $31.0M from the NCI; (7) increasing interventional accruals by 15%, with 34% minority treatment accruals in CY22 in our CA; and (8) developing 51 new Investigator Initiated Trials (out of a total of 86 actively open), and 45 FDA INDs; (9) launching several major initiatives including a unique collaboration between UCCCC and Argonne National Laboratories. The Center is a full member of the National Comprehensive Cancer Network, Alliance for Clinical Trials in Oncology, the Children’s Oncology Group and participates in NRG Oncology studies as a LAPS main member. The aims of UCCCC in the next funding period are to: (1) catalyze and conduct innovative, collaborative cancer research; (2) accelerate the translation of UCCCC member discoveries; (3) reduce cancer burden and disparities in our CA and accelerate health equity in historically underserved populations; (4) promote education, training, and mentorship; and (5) integrate DEI throughout the fabric of the UCCCC. Institutional commitment for the next funding period includes a $815M project to build a free- standing Cancer Pavilion.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $4,523,619 )
2025	2025	UNIVERSITY OF CHICAGO	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	002	49	4/30/2025	NON-COMPETING CONTINUATION	$4,071,258
2025	2025	UNIVERSITY OF CHICAGO	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	003	49	5/23/2025	NON-COMPETING CONTINUATION	$452,361
2025	2024	UNIVERSITY OF CHICAGO	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	001	48	4/23/2025	COMPETING CONTINUATION	$493,754
2025	2023	UNIVERSITY OF CHICAGO	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	000	47	4/23/2025	SUPPLEMENT FOR EXPANSION	-$493,754
														Subtotal = $4,523,619

Issue Date FY: 2024 ( Subtotal = $4,523,619 )
2024	2024	UNIVERSITY OF CHICAGO	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	000	48	3/26/2024	COMPETING CONTINUATION	$4,523,619
														Subtotal = $4,523,619

Issue Date FY: 2023 ( Subtotal = $4,540,866 )
2023	2023	UNIVERSITY OF CHICAGO	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	001	47	4/12/2023	SUPPLEMENT FOR EXPANSION	$4,466,201
2023	2023	UNIVERSITY OF CHICAGO	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	002	47	4/13/2023	SUPPLEMENT FOR EXPANSION	$74,665
2023	2022	UNIVERSITY OF CHICAGO	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	000	47	4/6/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,540,866

Issue Date FY: 2022 ( Subtotal = $4,547,150 )
2022	2022	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	003	47	5/9/2022	SUPPLEMENT FOR EXPANSION	$46,712
2022	2022	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	000	47	5/4/2022	NON-COMPETING CONTINUATION	$4,442,539
2022	2022	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	001	47	5/5/2022	SUPPLEMENT FOR EXPANSION	$64,685
2022	2021	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	002	46	5/6/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2017	UNIVERSITY OF CHICAGO	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	004	42	9/8/2022	NON-COMPETING CONTINUATION	-$6,786
														Subtotal = $4,547,150

Issue Date FY: 2021 ( Subtotal = $4,708,136 )
2021	2021	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	005	46	9/14/2021	SUPPLEMENT FOR EXPANSION	$115,000
2021	2021	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	004	46	5/18/2021	SUPPLEMENT FOR EXPANSION	$59,999
2021	2021	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	002	46	3/31/2021	SUPPLEMENT FOR EXPANSION	$64,685
2021	2021	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	001	46	3/30/2021	NON-COMPETING CONTINUATION	$4,468,452
2021	2021	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	003	46	4/1/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	000	45	3/12/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,708,136

Issue Date FY: 2020 ( Subtotal = $5,002,300 )
2020	2020	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	006	45	9/8/2020	SUPPLEMENT FOR EXPANSION	$99,999
2020	2020	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	007	45	9/9/2020	SUPPLEMENT FOR EXPANSION	$149,999
2020	2020	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	004	45	6/9/2020	SUPPLEMENT FOR EXPANSION	$104,166
2020	2020	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	002	45	5/11/2020	NON-COMPETING CONTINUATION	$4,468,452
2020	2020	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	005	45	7/17/2020	SUPPLEMENT FOR EXPANSION	$64,685
2020	2020	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	003	45	5/18/2020	SUPPLEMENT FOR EXPANSION	$114,999
2020	2019	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	001	44	3/26/2020	NON-COMPETING CONTINUATION	$0
2020	2018	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	000	43	3/25/2020	COMPETING CONTINUATION	$0
														Subtotal = $5,002,300

Issue Date FY: 2019 ( Subtotal = $4,933,445 )
2019	2019	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	010	44	4/2/2019	SUPPLEMENT FOR EXPANSION	$60,000
2019	2019	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	011	44	4/3/2019	SUPPLEMENT FOR EXPANSION	$249,998
2019	2019	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	009	44	4/1/2019	NON-COMPETING CONTINUATION	$4,468,452
2019	2019	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	012	44	6/18/2019	SUPPLEMENT FOR EXPANSION	-$60,000
2019	2019	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	014	44	8/6/2019	SUPPLEMENT FOR EXPANSION	$99,995
2019	2019	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	013	44	8/1/2019	SUPPLEMENT FOR EXPANSION	$115,000
2019	2018	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	007	43	12/18/2018	COMPETING CONTINUATION	$795,246
2019	2018	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	003	43	12/14/2018	COMPETING CONTINUATION	$0
2019	2017	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	002	42	10/25/2018	SUPPLEMENT FOR EXPANSION	$0
2019	2017	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	008	42	12/18/2018	SUPPLEMENT FOR EXPANSION	-$145,832
2019	2017	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	000	42	10/23/2018	SUPPLEMENT FOR EXPANSION	$0
2019	2017	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	004	42	12/18/2018	NON-COMPETING CONTINUATION	-$405,984
2019	2017	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	006	42	12/18/2018	SUPPLEMENT FOR EXPANSION	-$125,000
2019	2017	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	005	42	12/18/2018	SUPPLEMENT FOR EXPANSION	-$118,430
2019	2017	UNIVERSITY OF CHICAGO, THE	5801 S ELLIS AVE	CHICAGO	IL	60637	COOK	USA	Cancer Centers Support Grants	001	42	10/24/2018	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $4,933,445

Issue Date FY: 2018 ( Subtotal = $4,711,102 ) (Continued on the next page)
Grand Total All Awards = $117,626,122

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Cancer Center Support Grant

Award Number: P30CA014599

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/1997

PERIOD OF PERFORMANCE END DATE: 03/31/2029

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