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 | Issue Date FY: 2026 ( Subtotal = $112,922,841 ) (Continued on the next page) |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R01DK138355 | Metabolic Regulation of Colonic Senescence and Pathological Implications: Epithelial and Microbial Interactions | 000 | 3 | NIH | 1/9/2026 | $582,185 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R01CA217987 | Metabolic barriers to T cell activation in clear cell renal cell carcinoma | 003 | 10 | NIH | 3/19/2026 | $521,263 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R21HG014303 | Deciphering the relation between genetic relatedness and phenotypic covariance | 000 | 2 | NIH | 6/3/2026 | $237,296 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | U2RTW010122 | 2/2 Bangladesh Center for Global Environmental and Occupational Health-US | 000 | 10 | NIH | 6/11/2026 | $100,000 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | U2RTW010122 | 2/2 Bangladesh Center for Global Environmental and Occupational Health-US | 000 | 10 | NIH | 6/11/2026 | $118,500 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | U2RTW010122 | 2/2 Bangladesh Center for Global Environmental and Occupational Health-US | 000 | 10 | NIH | 6/11/2026 | $74,083 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R21EB036678 | Engineer A Chemogenetic Toolbox for Unraveling Complex Signaling Networks | 000 | 2 | NIH | 5/7/2026 | $321,146 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | P30DK020595 | Diabetes Research and Training Center | 000 | 49 | NIH | 4/6/2026 | $1,367,386 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F30AI183709 | Developmental acquisition of memory-phenotype CD8+ T cell function in infection and cancer | 000 | 2 | NIH | 4/3/2026 | $55,114 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R01EY012549 | Cell-Cell Signaling In Embryonic and Retinal Development-Revised Renewal | 000 | 21 | NIH | 1/29/2026 | $478,870 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R01CA232882 | Virally-induced tumorigenesis controlled by the microbiota | 000 | 7 | NIH | 2/27/2026 | $534,676 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R01AI183624 | BATF as an inducible regulator of natural killer cell expansion and effector function | 000 | 2 | NIH | 1/22/2026 | $550,902 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | UG1CA233327 | UG1 - NCTN (Network Lead) | 000 | 7 | NIH | 5/14/2026 | $701,399 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R61CA297947 | Enriching and Base-Resolution Profiling of 5-Methylcytosine in Degraded Clinical Samples | 001 | 2 | NIH | 4/16/2026 | $23,001 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R61CA297947 | Enriching and Base-Resolution Profiling of 5-Methylcytosine in Degraded Clinical Samples | 000 | 2 | NIH | 1/7/2026 | $207,009 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R21CA299377 | Unraveling Metastasis Drivers in Small Cell Lung Cancer via Human Pluripotent Stem Cell-Based Approach | 000 | 2 | NIH | 3/5/2026 | $191,675 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R21HL177730 | Hedgehog Signaling as a regulator of progenitor differentiation for organ maintenance and disease | 001 | 2 | NIH | 4/1/2026 | $6,150 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R21HL177730 | Hedgehog Signaling as a regulator of progenitor differentiation for organ maintenance and disease | 000 | 2 | NIH | 2/11/2026 | $116,850 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F32AI179006 | The Role of Host Genetics in Shaping Intestinal Lactobacillus Population | 001 | 3 | NIH | 4/2/2026 | $1,356 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F32AI179006 | The Role of Host Genetics in Shaping Intestinal Lactobacillus Population | 000 | 3 | NIH | 2/13/2026 | $83,224 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R37CA262781 | Liquid biopsy approaches to inform neuroblastoma prognosis and disease monitoring | 000 | 5 | NIH | 5/4/2026 | $622,186 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R35GM149521 | Theory, Methods, and Resources for Understanding and Leveraging Spatial Variation in Population Genetic Data | 000 | 4 | NIH | 5/27/2026 | $396,586 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R35GM151211 | Revealing mechanisms of specificity and adaptability in molecular information processing through data-driven models | 000 | 4 | NIH | 5/26/2026 | $382,830 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | U24NS107233 | Chicago Stroke Trials Consortium | 001 | 8 | NIH | 2/28/2026 | $43,747 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | U24NS107233 | Chicago Stroke Trials Consortium | 000 | 8 | NIH | 2/2/2026 | $393,723 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F30CA288116 | Unlocking the Diagnostic and Prognostic Potential of 5hmC in Urine cfDNA: Characterization of Genome-wide Landscape in Healthy Urine and Biomarker Development in Localized Bladder Cancer | 001 | 3 | NIH | 4/16/2026 | $576 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F30CA288116 | Unlocking the Diagnostic and Prognostic Potential of 5hmC in Urine cfDNA: Characterization of Genome-wide Landscape in Healthy Urine and Biomarker Development in Localized Bladder Cancer | 000 | 3 | NIH | 3/27/2026 | $54,538 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F31NS136004 | Uncovering DIP-α signaling pathways underlying circuit assembly | 001 | 3 | NIH | 4/27/2026 | $576 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F31NS136004 | Uncovering DIP-α signaling pathways underlying circuit assembly | 000 | 3 | NIH | 12/16/2025 | $49,538 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R01GM163190 | Electric-Field Stimulated Protein Dynamics | 000 | 1 | NIH | 5/7/2026 | $2,506,748 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R35GM161534 | Statistical methods to link genetic variants to regulatory landscapes | 000 | 1 | NIH | 2/27/2026 | $451,000 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R01NS149493 | Afferent proprioceptive signaling in Drosophila larvae | 000 | 1 | NIH | 5/11/2026 | $603,293 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R35GM161754 | Evolution-based understanding and design of proteins | 000 | 1 | NIH | 2/27/2026 | $487,525 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R21AI191042 | A Sicangu-driven social network strategy for syphilis prevention | 000 | 1 | NIH | 4/9/2026 | $417,567 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R35GM162500 | Causal Inference in Genetics: Integrative Methods for Mendelian Randomization and Single-Cell CRISPR Screening | 000 | 1 | NIH | 3/10/2026 | $410,000 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F31HD118780 | Causes and consequences of differential gene regulation in the development of alternate phenotypes | 002 | 1 | NIH | 4/3/2026 | $576 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F31HD118780 | Causes and consequences of differential gene regulation in the development of alternate phenotypes | 001 | 1 | NIH | 2/10/2026 | $0 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F31HD118780 | Causes and consequences of differential gene regulation in the development of alternate phenotypes | 000 | 1 | NIH | 2/10/2026 | $49,538 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R35GM162640 | The impact of demography and selection on the genetic architecture of human traits | 000 | 1 | NIH | 3/11/2026 | $451,000 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R35GM161741 | Natural variation of embryo development across the insect order of flies | 000 | 1 | NIH | 4/6/2026 | $480,083 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R33NS135583 | Kinetic analysis of acute stroke secondary prevention trials: Insights from combined datasets guiding future trial design | 001 | 3 | NIH | 4/8/2026 | $41,364 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R33NS135583 | Kinetic analysis of acute stroke secondary prevention trials: Insights from combined datasets guiding future trial design | 000 | 3 | NIH | 2/9/2026 | $372,262 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R35GM164319 | Decoding the sequence basis of genome regulation | 000 | 1 | NIH | 5/18/2026 | $357,809 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | F31CA314328 | Therapeutic restoration of CUX1 in -7/del(7q) acute myeloid leukemia | 000 | 1 | NIH | 5/19/2026 | $50,114 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R01AG089671 | Enhancing the Pathology, Alzheimer’s and Related Dementias Study to Understand Ancestry, Pollution Exposure, and AD/ADRD(PARDoS APEX) | 000 | 1 | NIH | 2/10/2026 | $2,586,176 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R01MD019007 | Community OHCA Risk Prediction Using Machine Learning: A Multi-Domain Approach to Prevention and Preparedness | 000 | 1 | NIH | 4/20/2026 | $686,906 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R21TR006236 | A missense correcting tRNA therapy platform for genetic diseases | 000 | 1 | NIH | 4/28/2026 | $451,000 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | R21AI199121 | Development of Selective Antiviral RNA-Degrading Chimeras Mimicking Ribonuclease Activity | 000 | 1 | NIH | 6/11/2026 | $442,296 |
| | 2026 | 2026 | UNIVERSITY OF CHICAGO | 5801 S ELLIS AVE | CHICAGO | IL | 60637-5418 | COOK | USA | U01AI190013 | Cross-Tissue Multi-Omic Predictors of Allergic Disease Development and Progression in Early Life | 000 | 1 | NIH | 6/11/2026 | $1,625,664 |
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