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Cancer Center Support (Core) Grant

Award Number: P30CA014051
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/17/1997
PERIOD OF PERFORMANCE END DATE: 04/30/2025

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Cancer Center Support (Core) Grant - Overall: Summary/Abstract Over the past four decades, MIT has had a focused effort in cancer research, first in the form of the MIT Center for Cancer Research (CCR) and, since 2007, as the Koch Institute for Integrative Cancer Research at MIT. This effort has been continuously supported by a Cancer Center Support Grant (CCSG) from the National Cancer Institute (NCI), providing the designation as an NCI-designated Cancer Center at MIT. By supplying infrastructural support for Core Facilities and other organizational components of the Koch Institute as well as funds for faculty recruitment and pilot projects, this CCSG is a critical resource for cancer research at MIT. From the establishment of the CCR in 1974 to the transition to the Koch Institute and continuing to the present, the NCI Cancer Center designation has had a strong influence on the MIT administration, leading to significant institutional support over this entire period. The investment in construction of the Koch Institute building (opened in late 2010) is a recent indication of this support. The building brings together 27 cancer scientists and cancer-oriented engineers to form a highly inter-disciplinary and collaborative research environment. The building is also the hub of cancer research on the MIT campus, with a nearly equal number of Members of the Center having their laboratories in other research buildings nearby. The 56 Center Members are drawn from eight academic departments at the School of Science or School of Engineering at MIT. Beyond the discovery research and technology development being pursued by the Members of this Center, significant emphasis is placed on translational research in the form of collaborations with clinical centers and industry partners. Research in the Koch Institute is organized into three Programs. Each of these Programs has made significant advances over the current grant period. Program 1: Genetic & Cellular Programs in Cancer is co-led by Drs. Phillip Sharp, J Christopher Love, and Eliezer Calo. Program 2: Cancer Biology & Immunology is co-led by Drs. Richard Hynes, Dane Wittrup, and Stefani Spranger. Program 3: Systems and Engineering Approaches to Cancer is co-led by Drs. Michael Yaffe, Scott Manalis, and Angela Koehler. These Programs function to stimulate new research initiatives by their Members as well as to foster intra- and inter-programmatic collaborations. In aggregate the 56 Members of this Center have published 1006 cancer-related articles over the past grant period. Of those, nearly 18% have involved multiple Members. The Center has a cancer-related funding base of $58,596,507 TDC (see Data Tables 2A/2B).


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $3,755,041 )
2024	2024	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	53	6/25/2024	NON-COMPETING CONTINUATION	$3,755,041
														Subtotal = $3,755,041

Issue Date FY: 2023 ( Subtotal = $3,755,041 )
2023	2023	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	52	4/26/2023	NON-COMPETING CONTINUATION	$3,755,041
														Subtotal = $3,755,041

Issue Date FY: 2022 ( Subtotal = $3,755,041 )
2022	2022	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	51	5/3/2022	NON-COMPETING CONTINUATION	$3,755,041
														Subtotal = $3,755,041

Issue Date FY: 2021 ( Subtotal = $3,755,041 )
2021	2021	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	005	50	6/15/2021	NON-COMPETING CONTINUATION	$3,755,041
2021	2020	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	003	49	2/7/2021	COMPETING CONTINUATION	$2
2021	2020	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	004	49	3/29/2021	COMPETING CONTINUATION	$0
2021	2020	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	001	49	10/22/2020	COMPETING CONTINUATION	$221,683
2021	2019	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	48	10/22/2020	NON-COMPETING CONTINUATION	-$221,683
2021	2019	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	002	48	2/7/2021	NON-COMPETING CONTINUATION	-$2
														Subtotal = $3,755,041

Issue Date FY: 2020 ( Subtotal = $3,755,041 )
2020	2020	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	49	5/26/2020	COMPETING CONTINUATION	$3,755,041
														Subtotal = $3,755,041

Issue Date FY: 2019 ( Subtotal = $3,572,644 )
2019	2019	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	48	5/23/2019	NON-COMPETING CONTINUATION	$3,572,644
														Subtotal = $3,572,644

Issue Date FY: 2018 ( Subtotal = $3,572,644 )
2018	2018	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	47	5/1/2018	NON-COMPETING CONTINUATION	$3,572,644
														Subtotal = $3,572,644

Issue Date FY: 2017 ( Subtotal = $3,572,644 )
2017	2017	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	46	5/22/2017	NON-COMPETING CONTINUATION	$3,572,644
														Subtotal = $3,572,644

Issue Date FY: 2016 ( Subtotal = $4,714,477 )
2016	2016	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	002	45	9/14/2016	SUPPLEMENT FOR EXPANSION	$746,692
2016	2016	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	45	5/31/2016	NON-COMPETING CONTINUATION	$3,572,644
2016	2016	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	001	45	9/13/2016	SUPPLEMENT FOR EXPANSION	$395,141
														Subtotal = $4,714,477

Issue Date FY: 2015 ( Subtotal = $3,572,644 )
2015	2015	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	44	7/9/2015	COMPETING CONTINUATION	$3,572,644
														Subtotal = $3,572,644

Issue Date FY: 2014 ( Subtotal = $3,738,697 )
2014	2014	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	43	8/22/2014	NON-COMPETING CONTINUATION	$3,738,697
														Subtotal = $3,738,697

Issue Date FY: 2013 ( Subtotal = $3,603,798 )
2013	2013	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	42	6/13/2013	NON-COMPETING CONTINUATION	$3,603,798
														Subtotal = $3,603,798

Issue Date FY: 2012 ( Subtotal = $3,854,329 )
2012	2012	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	41	5/4/2012	NON-COMPETING CONTINUATION	$3,854,329
														Subtotal = $3,854,329

Issue Date FY: 2011 ( Subtotal = $3,854,331 )
2011	2011	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	40	6/27/2011	NON-COMPETING CONTINUATION	$3,854,331
														Subtotal = $3,854,331

Issue Date FY: 2010 ( Subtotal = $4,057,188 )
2010	2010	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	39	9/20/2010	COMPETING CONTINUATION	$4,057,188
														Subtotal = $4,057,188

Issue Date FY: 2009 ( Subtotal = $2,844,058 )
2009	2009	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Treatment Research	001	38	5/26/2009	NON-COMPETING CONTINUATION	$2,844,058
2009	2008	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Treatment Research	000	37	11/27/2008	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,844,058

Issue Date FY: 2008 ( Subtotal = $2,844,058 )
2008	2008	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Treatment Research	000	37	8/1/2008	NON-COMPETING CONTINUATION	$2,844,058
														Subtotal = $2,844,058

Issue Date FY: 2007 ( Subtotal = $2,815,899 )
2007	2007	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Treatment Research	000	36	5/21/2007	NON-COMPETING CONTINUATION	$2,815,899
														Subtotal = $2,815,899

Issue Date FY: 2006 ( Subtotal = $2,899,999 )
2006	2006	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Treatment Research	000	35	5/5/2006	NON-COMPETING CONTINUATION	$2,899,999
														Subtotal = $2,899,999

Issue Date FY: 2005 ( Subtotal = $2,900,000 )
2005	2005	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Treatment Research	000	34	8/30/2005	COMPETING CONTINUATION	$2,900,000
														Subtotal = $2,900,000

Issue Date FY: 2004 ( Subtotal = $2,551,002 )
2004	2004	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASS AVE, BLDG E19-583	CAMBRIDGE	MA	02139	MIDDLESEX	USA	Cancer Centers Support Grants	000	33	4/30/2004	NON-COMPETING CONTINUATION	$2,551,002
														Subtotal = $2,551,002

Grand Total All Awards = $86,378,980

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Cancer Center Support (Core) Grant

Award Number: P30CA014051

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/17/1997

PERIOD OF PERFORMANCE END DATE: 04/30/2025

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