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 | Issue Date FY: 2025 ( Subtotal = $133,501,832 ) (Continued on the next page) |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U19AI167899 | Maternal Omics to Maximize Immunity | 001 | 4 | NIH | 5/19/2025 | $1,528,024 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U19AI167899 | Maternal Omics to Maximize Immunity | 001 | 4 | NIH | 5/19/2025 | $825,959 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32MH139162 | A multifunctional fiber platform for wireless, volumetric imaging and modulation of neural activity in vivo | 000 | 2 | NIH | 8/26/2025 | $80,520 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99CA287057 | Dietary Control of the Pro-Metastatic Niche in Colorectal Cancer | 000 | 2 | NIH | 12/13/2024 | $142,301 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99EY035752 | Dissecting distinct contributions of different Prefrontal subregions on goal-directed visual attention | 000 | 2 | NIH | 7/29/2025 | $125,734 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC021970 | The brainstem vocal control circuits | 000 | 2 | NIH | 5/14/2025 | $558,565 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | UM1CA294108 | Chemical Approaches to Modulate PAX3-FOXO1 in Fusion-Positive Alveolar Rhabdomyosarcoma | 001 | 2 | NIH | 8/28/2025 | $2,271,313 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U54CA283114 | Quantitative systems biology of glioblastoma cells and their interactions with the neuronal and immunological milieu | 000 | 3 | NIH | 9/22/2025 | $2,002,011 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HL167947 | Atraumatic Non-fibrotic Epicardial Pacing with E-Bioadhesive Devices | 000 | 3 | NIH | 8/6/2025 | $635,663 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA220468 | Bottlebrush polymer prodrugs for targeted delivery of combination therapies and in vivo imaging of pharmacological response | 002 | 8 | NIH | 6/12/2025 | $59,592 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA220468 | Bottlebrush polymer prodrugs for targeted delivery of combination therapies and in vivo imaging of pharmacological response | 000 | 8 | NIH | 11/18/2024 | $536,334 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG069232 | Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention | 001 | 4 | NIH | 8/4/2025 | $55,324 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG069232 | Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention | 000 | 4 | NIH | 1/9/2025 | $622,402 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148220 | Protein Chemistry | 002 | 3 | NIH | 8/6/2025 | $50,270 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148220 | Protein Chemistry | 001 | 3 | NIH | 1/27/2025 | $452,433 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH135141 | The role of top-down dendritic processing in credit assignment and cortical dynamics | 003 | 2 | NIH | 5/22/2025 | $103,927 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH135141 | The role of top-down dendritic processing in credit assignment and cortical dynamics | 001 | 2 | NIH | 4/17/2025 | $588,915 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM159321 | Structures and Dynamics of Proton- and Cation-Conducting Viroporins | 000 | 15 | NIH | 9/12/2025 | $378,680 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM156065 | Elucidating the Dynamics and Function of Long-Range Polycomb Interactions | 001 | 1 | NIH | 7/25/2025 | $0 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM156065 | Elucidating the Dynamics and Function of Long-Range Polycomb Interactions | 000 | 1 | NIH | 7/25/2025 | $75,520 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | RC2NS138558 | Transforming Research Rigor in a Leading Neuroscience Department using a Comprehensive Culture Change Approach | 000 | 1 | NIH | 7/24/2025 | $1,045,760 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS139886 | Highspeed Image Sensor and Microscopy Methods for Resolving Millisecond Scale Neural Dynamics in Freely Moving Mice and Zebrafish | 001 | 1 | NIH | 8/7/2025 | -$1,362,172 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB031813 | NMR-Based Rapid Fluid Assessment: Device Design and Signal Processing | 001 | 4 | NIH | 6/25/2025 | $54,018 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB031813 | NMR-Based Rapid Fluid Assessment: Device Design and Signal Processing | 000 | 4 | NIH | 2/18/2025 | $486,160 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS139886 | Highspeed Image Sensor and Microscopy Methods for Resolving Millisecond Scale Neural Dynamics in Freely Moving Mice and Zebrafish | 001 | 1 | NIH | 8/7/2025 | $1,362,172 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS139886 | Highspeed Image Sensor and Microscopy Methods for Resolving Millisecond Scale Neural Dynamics in Freely Moving Mice and Zebrafish | 000 | 1 | NIH | 7/30/2025 | $1,362,172 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | UH3MH126869 | Developing cell type-specific enhancers and connectivity mapping pipelines for marmosets | 000 | 4 | NIH | 7/29/2025 | $1,429,916 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24DA064429 | BBQS AI Resource and Data Coordinating Center (BARD.CC) | 000 | 2 | NIH | 7/29/2025 | $1,798,692 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM161042 | Structural investigations into the regulatory states of human Ribonucleotide Reductase | 000 | 1 | NIH | 9/2/2025 | $74,632 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM159370 | Deracemization of Beta2- and Gamma2-amino acids | 000 | 1 | NIH | 9/4/2025 | $75,052 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R24MH117295 | DANDI: Distributed Archives for Neurophysiology Data Integration | 002 | 7 | NIH | 4/25/2025 | $1,637,034 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K00AG079817 | Stress Response Mechanisms Regulating Neuronal Health in the Mammalian Central Nervous System. | 000 | 2 | NIH | 8/29/2025 | $92,232 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 000 | 1 | NIH | 9/8/2025 | $100,000 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 000 | 1 | NIH | 9/8/2025 | $433,198 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 000 | 1 | NIH | 9/8/2025 | $250,000 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM160726 | High Throughput End-to-End Design of Quantitative Phase Microscopy based on Customizable Nano-Optics | 000 | 1 | NIH | 8/6/2025 | $1,963,850 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH085802 | Early developmental mechanisms of Rett Syndrome | 001 | 15 | NIH | 9/18/2025 | $58,162 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH085802 | Early developmental mechanisms of Rett Syndrome | 000 | 15 | NIH | 2/13/2025 | $329,588 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99CA300496 | Determining how cancer cachexia influences gluconeogenesis | 000 | 1 | NIH | 8/7/2025 | $133,955 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DA063327 | Integration and Validation of Single-Cell Neuronal and Immune Molecular Responses in SUD and HIV | 000 | 1 | NIH | 7/8/2025 | $558,668 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | DP2HL168072 | Circulatronics: A New Paradigm for Biomedical Implants | 000 | 2 | NIH | 8/19/2025 | $954,000 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R56AI055258 | Synthetic Ligands for Directing Immune Responses | 000 | 21 | NIH | 8/20/2025 | $350,000 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99HG014240 | Functional Mapping of Translation Initiation Kinetics to Quantify the Protein-Coding Capacity of the Human Genome | 000 | 1 | NIH | 8/18/2025 | $133,332 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21AI193817 | Molecular Tailoring of Bispecific Antibody–BottlebrushConjugates | 000 | 1 | NIH | 7/1/2025 | $386,194 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS129032 | Single-cell multi-region transcriptional and epigenomic dissection of VCID. | 000 | 2 | NIH | 8/5/2025 | $1,034,087 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | T32GM158496 | Interdisciplinary graduate training for the next generation of computational and systems biologists | 000 | 1 | NIH | 7/23/2025 | $321,270 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG087374 | Lipid imaging expansion microscopy to study Alzheimer's disease | 001 | 2 | NIH | 6/9/2025 | $61,691 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM144542 | Tools to determine and analyze the structures of molecular machines in motion | 001 | 4 | NIH | 8/8/2025 | $31,886 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG087374 | Lipid imaging expansion microscopy to study Alzheimer's disease | 000 | 2 | NIH | 3/6/2025 | $694,036 |
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