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 | Issue Date FY: 2026 ( Subtotal = $11,172,084 ) (Continued on the next page) |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EY029666 | Neural Mechanisms for Feature-Based Attention | 000 | 8 | NIH | 1/9/2026 | $555,564 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA220468 | Bottlebrush polymer prodrugs for targeted delivery of combination therapies and in vivo imaging of pharmacological response | 000 | 9 | NIH | 12/16/2025 | $536,334 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA235375 | Delivery of cytokines for cancer immunotherapy using nanolayer-controlled trafficking of liposomal nanoparticles | 000 | 7 | NIH | 1/9/2026 | $318,532 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG087374 | Lipid imaging expansion microscopy to study Alzheimer's disease | 000 | 3 | NIH | 1/26/2026 | $694,036 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R00NS128717 | Developing Tools to Probe DnaJB6 Dynamics in Spinobulbular Muscular Atrophy | 000 | 3 | NIH | 12/15/2025 | $224,100 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM157940 | Machine Learning and Automated Flow Synthesis for the Development of Peptide Catalysts for the Stereo- and Site-Selective Formation of C–C Bonds | 000 | 2 | NIH | 1/8/2026 | $75,052 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM154448 | Investigating mechanisms of coordinating actinstructure across multiple levels oforder | 002 | 2 | NIH | 2/6/2026 | $81,040 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | UM1TR006029 | NAMs for Clinical Translation of Therapeutics for Systemic Gynecology Diseases | 000 | 1 | NIH | 2/6/2026 | $947,146 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | UM1TR006029 | NAMs for Clinical Translation of Therapeutics for Systemic Gynecology Diseases | 000 | 1 | NIH | 2/6/2026 | $2,315,231 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM156872 | Chemical Approaches to Understanding the Mechanisms of Iron-Sulfur Enzymes | 000 | 2 | NIH | 1/22/2026 | $508,005 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM157624 | Cationic Carbone-Boracycles as Far-Red and Near-Infrared Photoactive Agents | 000 | 2 | NIH | 12/17/2025 | $321,628 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148220 | Protein Chemistry | 000 | 4 | NIH | 1/22/2026 | $452,433 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148343 | Mechanisms and regulation of replication, the cell cycle, gene expression, and horizontal gene transfer in prokaryotes, focusing on Bacillus subtilis. | 000 | 4 | NIH | 1/19/2026 | $672,792 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM144115 | Tissue morphogenesis: From signals to forces | 000 | 5 | NIH | 1/7/2026 | $489,141 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21AG099044 | Pilot of a new non-viral vector for therapeutic nucleic acid delivery to the CNS | 000 | 1 | NIH | 1/21/2026 | $466,340 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21HL177773 | Emulated Target Trials of Steroids in Patients with Acute Respiratory Distress Syndrome | 000 | 2 | NIH | 2/11/2026 | $123,599 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HL162564 | Nonviral delivery techniques for in vivo prime editing | 000 | 5 | NIH | 2/2/2026 | $387,750 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH131715 | Layer-specific manipulation to test feedforward/feedback cortical circuitry | 000 | 4 | NIH | 1/14/2026 | $286,798 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH112694 | Simultaneous profiling of neuronal synapse activities, proteins, and messenger RNAs at the single-cell level | 000 | 7 | NIH | 1/15/2026 | $402,000 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH104536 | Imaging Synaptic Transmission of Individual Active Zones | 000 | 12 | NIH | 2/10/2026 | $397,500 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH060379 | Functional and anatomical characterization of the striosomal system | 000 | 25 | NIH | 1/21/2026 | $387,750 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM144542 | Tools to determine and analyze the structures of molecular machines in motion | 000 | 5 | NIH | 1/21/2026 | $286,669 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC000238 | Experimental Theoretical Studies of Cochlear Mechanisms | 000 | 40 | NIH | 11/21/2025 | $331,137 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC000238 | Experimental Theoretical Studies of Cochlear Mechanisms | 001 | 40 | NIH | 2/10/2026 | $36,793 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA249151 | Increasing nerve-sparing radical prostatectomy rates using intraoperative nonlinear microscopy | 000 | 5 | NIH | 11/25/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG070135 | Sleep-dependent modulation of cerebrospinal fluid flow in aging | 000 | 6 | NIH | 12/12/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG067151 | Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD | 000 | 5 | NIH | 11/20/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99DK139418 | New siRNA therapeutics to halt diabetic kidney disease | 000 | 2 | NIH | 1/8/2026 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99HG014240 | Functional Mapping of Translation Initiation Kinetics to Quantify the Protein-Coding Capacity of the Human Genome | 000 | 1 | NIH | 12/3/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K00AG079817 | Investigating regeneration factors in the aging mammalian liver | 000 | 2 | NIH | 12/12/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM153117 | Stereochemical Editing of Quaternary Stereocenters Enabled by Enantioselective Recombination of C–C Bonds | 000 | 2 | NIH | 1/15/2026 | -$66,604 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31HL170537 | Optimization of Right and Left Ventricular Coupling During Mechanical Circulatory Support | 000 | 2 | NIH | 1/27/2026 | -$71 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U01EB031641 | Toward functional molecular neuroimaging using vasoactive probes in human subjects | 000 | 5 | NIH | 1/26/2026 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 000 | 1 | NIH | 12/1/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 000 | 1 | NIH | 12/1/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 000 | 1 | NIH | 12/1/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U01NS121471 | Computational Neuroscience of Language Processing in the Human Brain | 000 | 5 | NIH | 1/22/2026 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U01AG077227 | Mapping the vulnerable locus coeruleus pathways in aging and AD | 000 | 4 | NIH | 2/10/2026 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U01CA265706 | Immunotherapy via engineered therapeutic programs in tumors using RNA | 000 | 5 | NIH | 12/8/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U01CA265706 | Immunotherapy via engineered therapeutic programs in tumors using RNA | 000 | 5 | NIH | 12/8/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS117588 | Molecular and Cellular Mechanisms Mediating Structural and Functional Active Zone Maturation | 000 | 5 | NIH | 12/16/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH126351 | Spatiotemporal dynamics of locus coeruleus circuits during learned behavior | 000 | 5 | NIH | 12/9/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH085802 | Early developmental mechanisms of Rett Syndrome | 000 | 15 | NIH | 12/9/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM140108 | Mechanobiology of Vimentin Intermediate Filaments in 3D Collective Cell Migration | 000 | 5 | NIH | 10/17/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM160726 | High Throughput End-to-End Design of Quantitative Phase Microscopy based on Customizable Nano-Optics | 000 | 1 | NIH | 12/8/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HD110335 | Parsing the Interplay Between Biophysical and Biochemical Microenvironment Cues On Endometriosis Lesion Phenotypes Using Microphysiological Systems | 000 | 4 | NIH | 12/9/2025 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM039334 | Deciphering the Principles of Membrane-Associated Glycan Assembly for Glycoconjugate Biosynthesis | 000 | 36 | NIH | 1/15/2026 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EY037733 | How retinal silencing restores synaptic strength in visual cortex of adult amblyopia | 000 | 1 | NIH | 1/16/2026 | $0 |
| | 2026 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB031813 | NMR-Based Rapid Fluid Assessment: Device Design and Signal Processing | 000 | 4 | NIH | 11/18/2025 | $0 |
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