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 | Issue Date FY: 2026 ( Subtotal = $94,074,596 ) (Continued on the next page) |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA220468 | Bottlebrush polymer prodrugs for targeted delivery of combination therapies and in vivo imaging of pharmacological response | 000 | 9 | NIH | 12/16/2025 | $536,334 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | OT2CA297463 | MATCHMAKERS - Creating and training AI tools for TCR binding prediction and design | 001 | 1 | NIH | 5/13/2026 | $1,209,684 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HL167947 | Atraumatic Non-fibrotic Epicardial Pacing with E-Bioadhesive Devices | 000 | 4 | NIH | 7/16/2026 | $629,277 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K00AG083111 | Mechanisms of blood-brain barrier deterioration in vascular cognitive impairment and Alzheimers disease | 000 | 4 | NIH | 6/19/2026 | $94,603 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HD114214 | Integrating tissue engineering and microfluidics to model the spatial niches of the human endometrium in vitro with guidance from in vivo multiomics data | 001 | 4 | NIH | 6/25/2026 | $0 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HD114214 | Integrating tissue engineering and microfluidics to model the spatial niches of the human endometrium in vitro with guidance from in vivo multiomics data | 000 | 4 | NIH | 5/26/2026 | $539,092 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM154448 | Investigating mechanisms of coordinating actinstructure across multiple levels oforder | 002 | 2 | NIH | 2/6/2026 | $81,040 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K00AG073558 | Plasticity of cortical circuits in health, aging, and Alzheimer's disease | 000 | 5 | NIH | 6/19/2026 | $80,803 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31CA301546 | Investigating the influence of phospholipases onimmune evasion | 000 | 1 | NIH | 4/13/2026 | $50,114 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DK147407 | A Label-Free Imaging Platform to Resolve Age- and Lineage-Specific Lipid–Mitochondrial Interactions in the Enteric Nervous System | 000 | 1 | NIH | 7/10/2026 | $837,398 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K00CA294265 | Integrating multi-modal label-free single cell technology to target radiation resistance in pediatric diffuse midline glioma | 000 | 3 | NIH | 8/17/2026 | $90,820 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AI194916 | Visualization of nuclear pore passage of the HIV-1 capsid | 000 | 1 | NIH | 8/17/2026 | $553,136 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99AI192941 | Molecular host determinants of spotted fever group rickettsial infection | 000 | 1 | NIH | 8/18/2026 | $185,472 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21DC024042 | The Development and Testing of Cochlear Implant Strategies Using Machine Learning | 000 | 1 | NIH | 8/7/2026 | $421,839 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99CA307867 | Volumetric histopathology of surgical specimens: scalable 3D analysis in breast and prostate cancer | 000 | 1 | NIH | 8/7/2026 | $141,864 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB038310 | Synthetic Genetic Controller Circuits for Transcription Factor-Directed Differentiation | 000 | 1 | NIH | 5/18/2026 | $678,583 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | T32NS147931 | Predoctoral Training in Neuroscience and Cognitive Science | 000 | 1 | NIH | 6/30/2026 | $164,121 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS146371 | Establishing a bioelectronics-integrated mesoscale organ-on-a-chip for neuromuscular disease modeling | 000 | 1 | NIH | 8/19/2026 | $619,189 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21AI195384 | Cellular Glue Therapeutics to Enhance Innate Immune Responses Against Fungal Pathogens | 000 | 1 | NIH | 5/11/2026 | $172,028 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM164217 | Microbial Manipulation Of Eukaryotic Membranes | 000 | 1 | NIH | 6/12/2026 | $438,788 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31AI197535 | The molecular basis of T cell allorecognition in Graft-versus-Host-Disease and Graft-versus-Leukemia | 001 | 1 | NIH | 5/11/2026 | $0 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31AI197535 | The molecular basis of T cell allorecognition in Graft-versus-Host-Disease and Graft-versus-Leukemia | 000 | 1 | NIH | 5/11/2026 | $50,114 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99DK146116 | Enhancing intestinal regeneration with Cysteine mediated dietary intervention | 000 | 1 | NIH | 3/19/2026 | $90,000 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32AI203130 | Evaluation of Triscatecholate Sideophore Antibiotic Conjugates Towards Enteric Biofilm-Forming Pathogens | 000 | 1 | NIH | 8/11/2026 | $75,880 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99MH141244 | Role of a non-classical amygdala striatal pathway in selection of instrumental actions | 000 | 1 | NIH | 7/7/2026 | $127,224 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM163886 | Selective, Catalytic Isomerization Reactions | 000 | 1 | NIH | 6/26/2026 | $502,372 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 002 | 2 | NIH | 7/30/2026 | $250,000 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 001 | 2 | NIH | 7/21/2026 | $100,000 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 001 | 2 | NIH | 7/21/2026 | $444,238 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 001 | 2 | NIH | 7/21/2026 | $250,000 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM159321 | Structures and Dynamics of Proton- and Cation-Conducting Viroporins | 001 | 16 | NIH | 8/20/2026 | $99,175 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K00AG079817 | Investigating regeneration factors in the aging mammalian liver | 001 | 3 | NIH | 6/19/2026 | $94,603 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM159321 | Structures and Dynamics of Proton- and Cation-Conducting Viroporins | 000 | 16 | NIH | 8/10/2026 | $345,671 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99HG014240 | Functional Mapping of Translation Initiation Kinetics to Quantify the Protein-Coding Capacity of the Human Genome | 001 | 2 | NIH | 8/6/2026 | $133,332 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DA063327 | Integration and Validation of Single-Cell Neuronal and Immune Molecular Responses in SUD and HIV | 000 | 2 | NIH | 3/4/2026 | $534,720 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21AG099044 | Pilot of a new non-viral vector for therapeutic nucleic acid delivery to the CNS | 000 | 1 | NIH | 1/21/2026 | $466,340 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM164515 | Design and optimization of high refractive index proteins for deep tissue imaging in living biological systems | 000 | 1 | NIH | 6/19/2026 | $655,926 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS144823 | Spatially Multiplexed Imaging of Complex Signaling Networks | 000 | 1 | NIH | 5/5/2026 | $651,069 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM161729 | Biophysical models of genome folding and function | 000 | 1 | NIH | 6/18/2026 | $440,465 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31DK149560 | Synthetic control of angiocrine signaling in vascularized liver implants | 000 | 1 | NIH | 8/14/2026 | $50,114 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31HL186649 | Single-Cell Profiling of Red Blood Cell Density and Sickling to Reveal Patient Heterogeneity in Sickle Cell Anemia | 000 | 1 | NIH | 7/23/2026 | $50,114 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31NS151509 | Midnolin-dependent nuclear proteostasis in striatal circuits in Parkinson’s diseasedyskinesia and Huntington’s disease | 000 | 1 | NIH | 8/14/2026 | $50,114 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R00CA286968 | Quantitative modeling of extrachromosomal DNA (ecDNA) evolution in tumors | 000 | 3 | NIH | 3/5/2026 | $248,618 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21EY037441 | Myelin Plasticity in the Visual System Following Extended Visual Deprivation | 000 | 1 | NIH | 7/17/2026 | $406,439 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99NS151133 | Modulation of autonomic function by affective pain pathways | 000 | 1 | NIH | 7/30/2026 | $129,168 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH141342 | The Role of Social Interactions in Promoting Recovery from Sickness Behaviors Through IL-10-Mediated Mechanisms | 000 | 1 | NIH | 8/3/2026 | $735,182 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21EY037441 | Myelin Plasticity in the Visual System Following Extended Visual Deprivation | 001 | 1 | NIH | 7/27/2026 | $0 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM161027 | Copper Hydride Catalyzed Anti-Markovnikov Hydration of Olefins | 001 | 1 | NIH | 7/24/2026 | $0 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM161027 | Copper Hydride Catalyzed Anti-Markovnikov Hydration of Olefins | 000 | 1 | NIH | 7/24/2026 | $76,300 |
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