| | | | | | | | | | | | | | | | |
| |
| Issue Date FY: 2024 ( Subtotal = $24,980,360 ) (Continued on the next page) |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HG002439 | Regulation and Function of Alternative mRNA Isoform Expression in Mammals | 000 | 20 | NIH | 1/4/2024 | $485,089 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB004866 | Innovative Instrumentation for High Magnetic Field DNP NMR | 000 | 16 | NIH | 1/4/2024 | $476,626 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM039334 | Deciphering the Principles of Membrane-Associated Glycan Assembly for Glycoconjugate Biosynthesis | 000 | 35 | NIH | 2/6/2024 | $372,536 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC000238 | Experimental Theoretical Studies of Cochlear Mechanisms | 000 | 38 | NIH | 11/28/2023 | $332,220 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HL161069 | Personalized lesion modification optimizes atherosclerosis intervention | 000 | 3 | NIH | 12/20/2023 | $620,595 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB031992 | SMART BIOELECTRONIC IMPLANTS FOR CONTROLLED DELIVERY OF THERAPEUTIC PROTEINS IN VIVO AND ITS APPLICATION IN LONG-TERM TREATMENT OF HEMOPHILIA A | 000 | 3 | NIH | 1/23/2024 | $544,206 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA271243 | Intratumoral Cytokine Immunotherapy Studies in Companion Canine Cancer Models | 000 | 3 | NIH | 3/14/2024 | $459,242 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32EY032756 | Visual cortex circuits mediating arousal and visual discrimination | 000 | 3 | NIH | 1/19/2024 | $76,272 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM145072 | Structure function investigations of radical transfer and disulfide exchange in a class Ia ribonucleotide reductase | 000 | 3 | NIH | 11/20/2023 | $71,792 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32HG012307 | Connecting perturbations of RNA binding proteins to their consequences | 000 | 3 | NIH | 11/16/2023 | $73,772 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31EY033996 | Elucidating the Role of Dorsal Lateral Geniculate Nucleus Burst-Mode Firing in Retinal Inactivation Induced Recovery from Monocular Deprivation | 000 | 3 | NIH | 3/12/2024 | $47,694 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG069232 | Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention | 000 | 3 | NIH | 1/22/2024 | $633,958 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM143898 | Determinants of elongation rate differences between B. subtilis and E. coli RNA polymerases | 000 | 3 | NIH | 2/14/2024 | $2,500 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U01NS121471 | Computational Neuroscience of Language Processing in the Human Brain | 000 | 4 | NIH | 2/15/2024 | $619,121 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB030946 | Synthetic gene sensors and effectors to redirect organoid development | 000 | 4 | NIH | 3/20/2024 | $578,545 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS117588 | Molecular and Cellular Mechanisms Mediating Structural and Functional Active Zone Maturation | 000 | 4 | NIH | 1/29/2024 | $348,975 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG070135 | Sleep-dependent modulation of cerebrospinal fluid flow in aging | 002 | 5 | NIH | 1/19/2024 | $563,393 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM141517 | Structure and function of ClpXP | 000 | 4 | NIH | 3/12/2024 | $348,975 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH126351 | Spatiotemporal dynamics of locus coeruleus circuits during learned behavior | 000 | 4 | NIH | 1/26/2024 | $393,065 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM140108 | Mechanobiology of Vimentin Intermediate Filaments in 3D Collective Cell Migration | 000 | 4 | NIH | 11/15/2023 | $378,500 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS119519 | Sensorimotor Learning Through Adjustments of Cortical Dynamics | 000 | 4 | NIH | 1/1/2024 | $348,975 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG067151 | Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD | 000 | 4 | NIH | 11/17/2023 | $652,503 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA249151 | Increasing nerve-sparing radical prostatectomy rates using intraoperative nonlinear microscopy | 000 | 4 | NIH | 1/24/2024 | $438,785 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM136882 | Modeling the Organometallic Chemistry of Radical S-adenosylmethionine Enzymes | 000 | 5 | NIH | 3/7/2024 | $263,350 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH121802 | Mutant Shank3 macaque monkeys for neurobiological studies of ASD | 000 | 5 | NIH | 1/17/2024 | $203,310 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA248280 | Rapid ex vivo biosensor cultures to assess dependencies in gastroesophageal cancer | 000 | 5 | NIH | 3/20/2024 | $515,148 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA247632 | Enhancing CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor | 000 | 5 | NIH | 12/15/2023 | $304,886 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EY029666 | Neural Mechanisms for Feature-Based Attention | 000 | 6 | NIH | 12/5/2023 | $555,564 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K00CA264312 | Cellular engineering to improve the efficacy and specificity of targeted immunotherapy | 000 | 3 | NIH | 3/13/2024 | $89,489 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM153091 | Developing Selective P-catalysts for Dehydrative Transformations | 001 | 1 | NIH | 1/10/2024 | $0 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM153091 | Developing Selective P-catalysts for Dehydrative Transformations | 000 | 1 | NIH | 1/10/2024 | $69,500 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99CA287057 | Dietary Control of the Pro-Metastatic Niche in Colorectal Cancer | 000 | 1 | NIH | 1/17/2024 | $142,301 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21AI181878 | Systematic identification of novel anti-phage defense mechanisms in the E. coli pangenome | 001 | 1 | NIH | 2/7/2024 | $0 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21AI181878 | Systematic identification of novel anti-phage defense mechanisms in the E. coli pangenome | 000 | 1 | NIH | 1/29/2024 | $214,650 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM153117 | Stereochemical Editing of Quaternary Stereocenters Enabled by Enantioselective Recombination of C?C Bonds | 001 | 1 | NIH | 1/19/2024 | $0 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM153117 | Stereochemical Editing of Quaternary Stereocenters Enabled by Enantioselective Recombination of C?C Bonds | 000 | 1 | NIH | 1/19/2024 | $68,684 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31EY033649 | Alignment of visual features in binocular cortical circuits through experience dependent synaptic plasticity | 000 | 2 | NIH | 12/12/2023 | $47,694 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS131457 | Brain-Wide Representations of Behavior During Aversive Internal States in C. Elegans | 000 | 2 | NIH | 2/9/2024 | $342,322 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F31MH133329 | A multi-modal, brain-wide atlas of astrocyte diversity across developmental stages and model species | 000 | 2 | NIH | 3/18/2024 | $47,694 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99GM149815 | Dissecting enhancer-promoter looping and gene induction dynamics in differentiation | 000 | 2 | NIH | 3/7/2024 | $125,000 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R00NS119749 | A New Animal Model to Examine Nervous System Function Development and Regeneration | 000 | 4 | NIH | 3/20/2024 | $194,436 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R37CA273819 | Understanding the induction of T cell dysfunction in the context of lung cancer | 000 | 2 | NIH | 3/7/2024 | $476,981 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH133066 | Neuron-astrocyte mechanisms of norepinephrine in goal-directed learning | 000 | 2 | NIH | 2/15/2024 | $583,392 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC020484 | Neural Mechanisms that Underlie Flexible Sensory Control of Behavioral States in C. elegans | 000 | 2 | NIH | 2/21/2024 | $343,340 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148220 | Protein Chemistry | 000 | 2 | NIH | 1/17/2024 | $427,375 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99GM148718 | Cytotoxicity and function of incomplete proteins | 000 | 2 | NIH | 1/9/2024 | $123,971 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AI175489 | "Extended dosing" immunization to enhance humoral immunity to next-generation vaccines | 000 | 2 | NIH | 1/31/2024 | $105,625 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AI175489 | "Extended dosing" immunization to enhance humoral immunity to next-generation vaccines | 000 | 2 | NIH | 1/31/2024 | $316,874 |
| 2024 | 2024 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH131715 | Layer-specific manipulation to test feedforward/feedback cortical circuitry | 000 | 2 | NIH | 11/28/2023 | $264,138 |
|