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 | Issue Date FY: 2025 ( Subtotal = $126,266,790 ) (Continued on the next page) |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24DA064429 | BBQS AI Resource and Data Coordinating Center (BARD.CC) | 000 | 2 | NIH | 7/29/2025 | $1,798,692 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB031813 | NMR-Based Rapid Fluid Assessment: Device Design and Signal Processing | 001 | 4 | NIH | 6/25/2025 | $54,018 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB031813 | NMR-Based Rapid Fluid Assessment: Device Design and Signal Processing | 000 | 4 | NIH | 2/18/2025 | $486,160 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM156282 | Drivers of adaptation and colonization within individual human microbiomes | 000 | 1 | NIH | 8/1/2025 | $557,900 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AR084097 | Determinants of colonization for commensal skin bacteria | 000 | 1 | NIH | 7/31/2025 | $465,291 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R61HL177503 | A transcatheter manufacturing toolkit for minimally-invasive and patient-specific device-based stroke prevention | 000 | 1 | NIH | 8/26/2025 | $397,034 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS129032 | Single-cell multi-region transcriptional and epigenomic dissection of VCID. | 000 | 2 | NIH | 8/5/2025 | $1,034,087 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH085802 | Early developmental mechanisms of Rett Syndrome | 000 | 15 | NIH | 2/13/2025 | $329,588 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99CA300496 | Determining how cancer cachexia influences gluconeogenesis | 000 | 1 | NIH | 8/7/2025 | $133,955 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM160726 | High Throughput End-to-End Design of Quantitative Phase Microscopy based on Customizable Nano-Optics | 000 | 1 | NIH | 8/6/2025 | $1,963,850 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM153117 | Stereochemical Editing of Quaternary Stereocenters Enabled by Enantioselective Recombination of C–C Bonds | 000 | 2 | NIH | 12/20/2024 | $73,828 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG069232 | Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention | 001 | 4 | NIH | 8/4/2025 | $55,324 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG069232 | Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention | 000 | 4 | NIH | 1/9/2025 | $622,402 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148220 | Protein Chemistry | 001 | 3 | NIH | 1/27/2025 | $452,433 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH135141 | The role of top-down dendritic processing in credit assignment and cortical dynamics | 003 | 2 | NIH | 5/22/2025 | $103,927 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01MH135141 | The role of top-down dendritic processing in credit assignment and cortical dynamics | 001 | 2 | NIH | 4/17/2025 | $588,915 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG067151 | Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD | 001 | 5 | NIH | 6/18/2025 | $57,192 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG067151 | Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD | 000 | 5 | NIH | 3/13/2025 | $643,438 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148220 | Protein Chemistry | 002 | 3 | NIH | 8/6/2025 | $50,270 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01NS135616 | Elucidating Neural Mechanisms Underlying Sickness Behaviors | 000 | 2 | NIH | 6/9/2025 | $474,348 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC021970 | The brainstem vocal control circuits | 000 | 2 | NIH | 5/14/2025 | $558,565 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HL161069 | Personalized lesion modification optimizes atherosclerosis intervention | 001 | 4 | NIH | 8/15/2025 | $68,467 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99DK139418 | New siRNA therapeutics to halt diabetic kidney disease | 000 | 2 | NIH | 8/12/2025 | $89,760 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01HL161069 | Personalized lesion modification optimizes atherosclerosis intervention | 000 | 4 | NIH | 1/3/2025 | $616,204 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21AI181878 | Systematic identification of novel anti-phage defense mechanisms in the E. coli pangenome | 000 | 2 | NIH | 11/19/2024 | $192,788 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U19AI167899 | Maternal Omics to Maximize Immunity | 003 | 4 | NIH | 9/10/2025 | $0 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U19AI167899 | Maternal Omics to Maximize Immunity | 003 | 4 | NIH | 9/10/2025 | $0 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U19AI167899 | Maternal Omics to Maximize Immunity | 001 | 4 | NIH | 5/19/2025 | $1,528,024 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U19AI167899 | Maternal Omics to Maximize Immunity | 001 | 4 | NIH | 5/19/2025 | $825,959 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U19AI167899 | Maternal Omics to Maximize Immunity | 002 | 4 | NIH | 6/17/2025 | $0 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DA063327 | Integration and Validation of Single-Cell Neuronal and Immune Molecular Responses in SUD and HIV | 000 | 1 | NIH | 7/8/2025 | $558,668 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K99HG014240 | Functional Mapping of Translation Initiation Kinetics to Quantify the Protein-Coding Capacity of the Human Genome | 000 | 1 | NIH | 8/18/2025 | $133,332 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM159370 | Deracemization of Beta2- and Gamma2-amino acids | 000 | 1 | NIH | 9/4/2025 | $75,052 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 000 | 1 | NIH | 9/8/2025 | $100,000 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 000 | 1 | NIH | 9/8/2025 | $433,198 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | U24EB037545 | PhysioNet: A FAIR and sustainable data repository | 000 | 1 | NIH | 9/8/2025 | $250,000 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | K00AG079817 | Stress Response Mechanisms Regulating Neuronal Health in the Mammalian Central Nervous System. | 000 | 2 | NIH | 8/29/2025 | $92,232 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM159321 | Structures and Dynamics of Proton- and Cation-Conducting Viroporins | 000 | 15 | NIH | 9/12/2025 | $378,680 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | DP2HL168072 | Circulatronics: A New Paradigm for Biomedical Implants | 000 | 2 | NIH | 8/19/2025 | $954,000 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R56AI055258 | Synthetic Ligands for Directing Immune Responses | 000 | 21 | NIH | 8/20/2025 | $350,000 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32GM161042 | Structural investigations into the regulatory states of human Ribonucleotide Reductase | 000 | 1 | NIH | 9/2/2025 | $74,632 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R24MH117295 | DANDI: Distributed Archives for Neurophysiology Data Integration | 002 | 7 | NIH | 4/25/2025 | $1,637,034 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R37CA273819 | Understanding the induction of T cell dysfunction in the context of lung cancer | 000 | 3 | NIH | 2/17/2025 | $415,926 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | UE5DA056914 | Program on Entrepreneurship and Innovation for Biomedical Product Development (EI4BPD) | 001 | 4 | NIH | 5/16/2025 | $330,802 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R37CA273819 | Understanding the induction of T cell dysfunction in the context of lung cancer | 001 | 3 | NIH | 5/23/2025 | $46,215 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32HD116425 | Developing a Biomimetic Lactating Mammary Lobe for Therapeutic Safety | 002 | 1 | NIH | 6/12/2025 | $1,284 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32HD116425 | Developing a Biomimetic Lactating Mammary Lobe for Therapeutic Safety | 001 | 1 | NIH | 3/19/2025 | $0 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21CA305319 | Directed evolution of TCRs with improved antigen sensitivity | 000 | 1 | NIH | 7/17/2025 | $414,803 |
| | 2025 | 2025 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32HD116425 | Developing a Biomimetic Lactating Mammary Lobe for Therapeutic Safety | 000 | 1 | NIH | 3/19/2025 | $76,756 |
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