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 | Issue Date FY: 2026 ( Subtotal = $32,460,381 ) (Continued on the next page) |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32HL178155 | Investigating the Role of Extracellular Matrix in Down Syndrome Associated Cardiac Phenotypes. | 001 | 2 | NIH | 5/8/2026 | $1,308 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | F32HL178155 | Investigating the Role of Extracellular Matrix in Down Syndrome Associated Cardiac Phenotypes. | 000 | 2 | NIH | 2/27/2026 | $81,040 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM114547 | Synthetic Methods based on Biphilic Phosphorus Catalysts | 000 | 13 | NIH | 4/21/2026 | $447,189 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM144542 | Tools to determine and analyze the structures of molecular machines in motion | 001 | 5 | NIH | 3/25/2026 | $31,852 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM144542 | Tools to determine and analyze the structures of molecular machines in motion | 000 | 5 | NIH | 1/21/2026 | $286,669 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01GM139055 | Diamond Rotors | 001 | 5 | NIH | 4/9/2026 | $373,600 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EB035127 | An integrated toolkit for real-time analysis of coupled nascent transcription | 000 | 3 | NIH | 2/18/2026 | $422,235 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EY011289 | Novel Optical Diagnostics with Optical Coherence Tomography | 000 | 39 | NIH | 4/2/2026 | $645,024 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01EY029666 | Neural Mechanisms for Feature-Based Attention | 000 | 8 | NIH | 1/9/2026 | $555,564 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC020484 | Neural Mechanisms that Underlie Flexible Sensory Control of Behavioral States in C. elegans | 000 | 4 | NIH | 2/17/2026 | $380,182 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC022604 | Testing a mechanistic model for the storage and recall of an auditory memory underlying sensorimotor vocal learning | 000 | 2 | NIH | 4/27/2026 | $430,605 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DA063327 | Integration and Validation of Single-Cell Neuronal and Immune Molecular Responses in SUD and HIV | 000 | 2 | NIH | 3/4/2026 | $534,720 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DA062195 | Analyzing brain-wide bases of neuroplastic change using new imaging tools | 000 | 2 | NIH | 2/25/2026 | $603,959 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC000238 | Experimental Theoretical Studies of Cochlear Mechanisms | 001 | 40 | NIH | 2/10/2026 | $36,793 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DC000238 | Experimental Theoretical Studies of Cochlear Mechanisms | 000 | 40 | NIH | 11/21/2025 | $331,137 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01DA054584 | Single-Cell Dissection of Ensembles and Cell Types Mediating Opioid Action in the Rodent Brain | 000 | 5 | NIH | 2/19/2026 | $616,630 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA290188 | Impact of DNA Repair Pathway Interactions on the Molecular and Physiological Consequences of Methylation Damage | 000 | 3 | NIH | 5/14/2026 | $411,850 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA235375 | Delivery of cytokines for cancer immunotherapy using nanolayer-controlled trafficking of liposomal nanoparticles | 000 | 7 | NIH | 1/9/2026 | $318,532 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA220468 | Bottlebrush polymer prodrugs for targeted delivery of combination therapies and in vivo imaging of pharmacological response | 001 | 9 | NIH | 4/16/2026 | $59,592 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01CA220468 | Bottlebrush polymer prodrugs for targeted delivery of combination therapies and in vivo imaging of pharmacological response | 000 | 9 | NIH | 12/16/2025 | $536,334 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AI162307 | Investigation of Synthetic DNA-based Viral Particles for Spatially Controlled Antigen Presentation | 001 | 5 | NIH | 2/9/2026 | $844,182 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG082871 | Disparities in the Quality of Nursing Home Care | 000 | 4 | NIH | 4/17/2026 | $613,270 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG087374 | Lipid imaging expansion microscopy to study Alzheimer's disease | 001 | 3 | NIH | 2/23/2026 | $77,114 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AG087374 | Lipid imaging expansion microscopy to study Alzheimer's disease | 000 | 3 | NIH | 1/26/2026 | $694,036 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R01AI126592 | Chemical Probes of Mycobacteria | 000 | 11 | NIH | 4/2/2026 | $579,261 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM156282 | Drivers of adaptation and colonization within individual human microbiomes | 000 | 2 | NIH | 4/28/2026 | $524,900 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM157624 | Cationic Carbone-Boracycles as Far-Red and Near-Infrared Photoactive Agents | 001 | 2 | NIH | 3/10/2026 | $35,736 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM157624 | Cationic Carbone-Boracycles as Far-Red and Near-Infrared Photoactive Agents | 000 | 2 | NIH | 12/17/2025 | $321,628 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM157324 | Biogeography of Microbial and Plant-Derived Redox-Active Small Molecules and Combinatorial Effects on Microbial Growth | 000 | 2 | NIH | 2/23/2026 | $393,718 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM156872 | Chemical Approaches to Understanding the Mechanisms of Iron-Sulfur Enzymes | 001 | 2 | NIH | 3/10/2026 | $56,445 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM156872 | Chemical Approaches to Understanding the Mechanisms of Iron-Sulfur Enzymes | 000 | 2 | NIH | 1/22/2026 | $508,005 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM158437 | Synthesis and Applications of Oligophosphate Constructs | 000 | 2 | NIH | 4/2/2026 | $402,867 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35NS137370 | Subcortico-Cortical Mechanisms of Sensorimotor Coordination, Integration, and Learning | 000 | 3 | NIH | 4/21/2026 | $531,141 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35NS127327 | Molecular Mechanisms Underlying Cell Type-Specific Vulnerability in Huntington’s Disease | 000 | 5 | NIH | 4/28/2026 | $542,850 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R37CA273819 | Understanding the induction of T cell dysfunction in the context of lung cancer | 000 | 4 | NIH | 2/26/2026 | $460,938 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148220 | Protein Chemistry | 001 | 4 | NIH | 3/10/2026 | $50,270 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148343 | Mechanisms and regulation of replication, the cell cycle, gene expression, and horizontal gene transfer in prokaryotes, focusing on Bacillus subtilis. | 001 | 4 | NIH | 3/23/2026 | $74,755 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148220 | Protein Chemistry | 000 | 4 | NIH | 1/22/2026 | $452,433 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM148343 | Mechanisms and regulation of replication, the cell cycle, gene expression, and horizontal gene transfer in prokaryotes, focusing on Bacillus subtilis. | 000 | 4 | NIH | 1/19/2026 | $672,792 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM144115 | Tissue morphogenesis: From signals to forces | 001 | 5 | NIH | 3/19/2026 | $54,349 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM144115 | Tissue morphogenesis: From signals to forces | 000 | 5 | NIH | 1/7/2026 | $489,141 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM124732 | Evolution and Regulation of Bacterial Proteome Composition | 000 | 9 | NIH | 2/17/2026 | $468,870 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM122483 | Metal-Catalyzed Methods for Organic Synthesis | 000 | 10 | NIH | 5/14/2026 | $1,141,967 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R35GM126982 | Metalloenzyme structure, function and assembly | 000 | 9 | NIH | 4/6/2026 | $410,347 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R24MH117295 | DANDI: Distributed Archives for Neurophysiology Data Integration | 000 | 8 | NIH | 5/13/2026 | $1,637,175 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R33CA291166 | Advanced Development of Patient Ascites Therapeutic Response Biosensors | 000 | 2 | NIH | 4/17/2026 | $394,605 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21HL177773 | Emulated Target Trials of Steroids in Patients with Acute Respiratory Distress Syndrome | 000 | 2 | NIH | 2/11/2026 | $123,599 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21AI195384 | Cellular Glue Therapeutics to Enhance Innate Immune Responses Against Fungal Pathogens | 000 | 1 | NIH | 5/11/2026 | $172,028 |
| | 2026 | 2026 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 77 MASSACHUSETTS AVE | CAMBRIDGE | MA | 02139-4301 | MIDDLESEX | USA | R21AG099044 | Pilot of a new non-viral vector for therapeutic nucleic acid delivery to the CNS | 000 | 1 | NIH | 1/21/2026 | $466,340 |
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