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Dana-Farber/Harvard Cancer Center

Award Number: P30CA006516
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Dana-Farber/Harvard Cancer Center - Overall Project Summary / Abstract Now in its 22nd year of operation, Dana-Farber/Harvard Cancer Center (DF/HCC) was the first consortium model, NCI-designated Comprehensive Cancer Center. The consortium is comprised of 1,100 members from five principal Harvard-affiliated hospitals and two Harvard health science schools: Beth Israel Deaconess Medical Center (BIDMC), Boston Children’s Hospital (BCH), Brigham and Women’s Hospital (BWH), Dana- Farber Cancer Institute (DFCI), Harvard Medical School (HMS), Harvard T. H. Chan School of Public Health (HSPH), and Massachusetts General Hospital (MGH). Our overarching goals are to identify the genetic, biological, environmental, and behavioral bases of cancer and to develop effective strategies to reduce risk and improve preventive and treatment outcomes. Our catchment area is the Commonwealth of Massachusetts. Our steady progress over the last two decades has depended on the combined resources and talent at the 7 institutions; the unique consortium structure that enables collaborative bench-to-bedside translational research by population, basic, and clinical members; and well-coordinated Center leadership. DF/HCC embodies: 1) an integrated structure that aspires to excellence in research and accelerates clinically effective discoveries, 2) a cohesive research community for cross-institutional and transdisciplinary collaborations, and 3) a collectively large patient population that expedites the conduct of innovative clinical trials. Our work occurs in 18 Research Programs that cross scientific and institutional boundaries and span the gamut of population, basic, and clinical cancer research; members excel in each sphere. Two entities, a Center for Cancer Equity and Engagement (CCEE) and an Office for Cancer Research Education and Training (OCRET), help fulfill our responsibilities to the catchment area and to train future leaders in cancer research. The Center supports 14 Shared Resources that provide members with quality research services that cannot easily be duplicated in individual laboratories or institutions. A unified clinical research infrastructure serves all seven consortium institutions and makes it possible for members to conduct innovative early-phase (proof-of-concept and Phase I/II) clinical trials across the consortium. A portfolio of grants that transcend organizational and disciplinary boundaries (e.g., SPOREs, Program Projects, SU2C Dream Teams) reflect our collective translational and collaborative ideals. Our next phase of work is guided by a multi-part Strategic Plan that emphasizes mechanistic understanding of cancer, early cancer detection, equity, new therapeutic avenues, and a renewed commitment to education and mentorship. Underlying these goals are a culture and infrastructure streamlined for collaborative investigation of populations, fundamental cellular and molecular mechanisms, primary tumor specimens, and the barriers to improved cancer-related outcomes in all segments of society.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	001	59	1/16/2025	SUPPLEMENT FOR EXPANSION	$0
2025	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	000	59	1/15/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $13,069,813 )
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	000	59	11/22/2023	NON-COMPETING CONTINUATION	$11,441,846
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	006	59	4/25/2024	SUPPLEMENT FOR EXPANSION	$221,854
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	002	59	1/26/2024	SUPPLEMENT FOR EXPANSION	$187,875
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	007	59	9/5/2024	SUPPLEMENT FOR EXPANSION	-$73,952
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	004	59	4/16/2024	NON-COMPETING CONTINUATION	$1,271,315
2024	2024	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	005	59	4/16/2024	SUPPLEMENT FOR EXPANSION	$20,875
2024	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	003	58	4/3/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	001	58	12/28/2023	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $13,069,813

Issue Date FY: 2023 ( Subtotal = $13,742,514 )
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	005	58	9/18/2023	SUPPLEMENT FOR EXPANSION	$495,880
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	006	58	9/22/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	002	58	6/23/2023	SUPPLEMENT FOR EXPANSION	$208,750
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	003	58	7/24/2023	SUPPLEMENT FOR EXPANSION	$224,723
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	000	58	1/25/2023	NON-COMPETING CONTINUATION	$12,713,161
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02215	SUFFOLK	USA	Cancer Centers Support Grants	004	58	9/15/2023	SUPPLEMENT FOR EXPANSION	$100,000
2023	2023	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	001	58	6/15/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $13,742,514

Issue Date FY: 2022 ( Subtotal = $13,004,730 )
2022	2022	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Trans-NIH Research Support	011	57	8/19/2022	SUPPLEMENT FOR EXPANSION	$178,000
2022	2022	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	000	57	12/13/2021	COMPETING CONTINUATION	$12,711,730
2022	2022	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	001	57	4/6/2022	SUPPLEMENT FOR EXPANSION	$115,000
2022	2022	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	010	57	4/9/2022	COMPETING CONTINUATION	$2,814,368
2022	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	009	56	4/9/2022	SUPPLEMENT FOR EXPANSION	-$340,000
2022	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	004	56	4/9/2022	SUPPLEMENT FOR EXPANSION	-$95,833
2022	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	005	56	4/9/2022	SUPPLEMENT FOR EXPANSION	-$59,999
2022	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	006	56	4/9/2022	SUPPLEMENT FOR EXPANSION	-$197,986
2022	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	007	56	4/9/2022	SUPPLEMENT FOR EXPANSION	-$19,167
2022	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	003	56	4/9/2022	SUPPLEMENT FOR EXPANSION	-$301,534
2022	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	008	56	4/9/2022	SUPPLEMENT FOR EXPANSION	-$299,999
2022	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	002	56	4/9/2022	NON-COMPETING CONTINUATION	-$1,499,850
														Subtotal = $13,004,730

Issue Date FY: 2021 ( Subtotal = $12,790,265 )
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	007	56	9/21/2021	SUPPLEMENT FOR EXPANSION	$299,999
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	008	56	9/22/2021	SUPPLEMENT FOR EXPANSION	$340,000
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	004	56	12/14/2020	NON-COMPETING CONTINUATION	-$353,818
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	000	56	11/10/2020	NON-COMPETING CONTINUATION	$11,829,565
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	006	56	9/20/2021	SUPPLEMENT FOR EXPANSION	$19,167
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	002	56	11/19/2020	SUPPLEMENT FOR EXPANSION	$59,999
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	003	56	11/30/2020	SUPPLEMENT FOR EXPANSION	$197,986
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	005	56	9/17/2021	SUPPLEMENT FOR EXPANSION	$301,534
2021	2021	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	001	56	11/17/2020	SUPPLEMENT FOR EXPANSION	$95,833
														Subtotal = $12,790,265

Issue Date FY: 2020 ( Subtotal = $12,918,673 ) (Continued on the next page)
2020	2020	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	007	55	7/17/2020	SUPPLEMENT FOR EXPANSION	$59,999
2020	2020	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	013	55	9/1/2020	SUPPLEMENT FOR EXPANSION	$149,753
2020	2020	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	010	55	8/24/2020	SUPPLEMENT FOR EXPANSION	$99,661
2020	2020	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	005	55	4/14/2020	SUPPLEMENT FOR EXPANSION	$115,000
2020	2020	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Centers Support Grants	004	55	4/7/2020	SUPPLEMENT FOR EXPANSION	$50,194
2020	2020	DANA-FARBER CANCER INSTITUTE, INC.	450 BROOKLINE AVE	BOSTON	MA	02115	SUFFOLK	USA	21st Century Cures Act - Beau Biden Cancer Moonshot	001	55	12/18/2019	SUPPLEMENT FOR EXPANSION	$187,500
Grand Total All Awards = $299,551,305

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Dana-Farber/Harvard Cancer Center

Award Number: P30CA006516

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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