Friday, July 4, 2025 7/4/2025

Visual Sciences Center of Biomedical Research Excellence

Award Number: P20GM144230
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/20/2022
PERIOD OF PERFORMANCE END DATE: 01/31/2027

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Visual Sciences Center of Biomedical Research Excellence - PROJECT SUMMARY/ABSTRACT The overarching goal of the Visual Sciences CoBRE (VS-CoBRE) is to optimize infrastructure and mentoring to support a sustainable, multidisciplinary, and collaborative research environment at WVU around visual sciences. The establishment of the VS-CoBRE will strengthen the scientific community focused on understanding processes that are essential to visual health with the long-term goal of contributing to novel approaches for prevention and treatment of blinding diseases that disproportionately affect Appalachia's population. West Virginia has the 2nd highest rate of visual disability in the nation, and the incidence is projected to double by 2050. We will achieve our goals by completing the following aims: Aim1, Support Project Leaders (PLs) to achieve independent extramural funding; Aim 2, Promote the fundamental understanding of the visual system through optimizing relevant technical infrastructure; Aim 3, Promote a comprehensive, multidisciplinary approach to impactful visual sciences research; and Aim 4: Implement a rigorous strategy to evaluate the effectiveness of the VS-CoBRE towards promoting a robust center of excellence in visual sciences. With our existing strengths and research infrastructure network, coupled with the initiatives proposed in this VS-CoBRE, including mentoring of our four-promising junior PLs, we are well-positioned to achieve our goal. The creation of a center of excellence provides a venue for integrating efforts across the campus, including activities supported by NIGMS including the WV CTSI and other CoBREs, the clinical enterprise in the Department of Ophthalmology and Visual Sciences, and investigations led by basic biologists in the Departments of Biochemistry, Neuroscience, Biology, and the program in Biomedical Engineering. The VS-CoBRE will coalesce vision scientists around a common theme, enhance the intellectual environment, and cultivate cross collaborations. When the investigators proposed for support by this grant achieve independence by obtaining an R01-equivalent award, we will leverage the VS-CoBRE to recruit additional junior scientists whose work pertains to visual sciences. The core facilities and research infrastructure supported by the CoBRE will also allow our investigators to produce research results that will translate to patients, moving us toward our ultimate goal of reducing the burden of visual impairment and its comorbidities in the Appalachian region, throughout the nation, and worldwide.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $2,279,830 )
2025	2025	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Biomedical Research and Research Training	000	4	5/21/2025	NON-COMPETING CONTINUATION	$2,279,830
														Subtotal = $2,279,830

Issue Date FY: 2024 ( Subtotal = $2,491,254 )
2024	2024	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Biomedical Research and Research Training	001	3	6/19/2024	NON-COMPETING CONTINUATION	$224,147
2024	2024	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Biomedical Research and Research Training	000	3	3/4/2024	NON-COMPETING CONTINUATION	$2,017,319
2024	2024	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Biomedical Research and Research Training	002	3	7/24/2024	SUPPLEMENT FOR EXPANSION	$249,788
														Subtotal = $2,491,254

Issue Date FY: 2023 ( Subtotal = $2,472,846 )
2023	2023	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Biomedical Research and Research Training	003	2	6/22/2023	SUPPLEMENT FOR EXPANSION	$249,972
2023	2023	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Biomedical Research and Research Training	002	2	2/20/2023	NON-COMPETING CONTINUATION	$222,288
2023	2023	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Biomedical Research and Research Training	001	2	2/1/2023	NON-COMPETING CONTINUATION	$2,000,586
2023	2022	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE ROAD	MORGANTOWN	WV	26505	MONONGALIA	USA	Biomedical Research and Research Training	000	1	1/31/2023	NEW	$0
														Subtotal = $2,472,846

Issue Date FY: 2022 ( Subtotal = $2,116,460 )
2022	2022	WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION	886 CHESTNUT RIDGE	MORGANTOWN	WV	26506	MONONGALIA	USA	Biomedical Research and Research Training	000	1	3/16/2022	NEW	$2,116,460
														Subtotal = $2,116,460

Grand Total All Awards = $9,360,390

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Visual Sciences Center of Biomedical Research Excellence

Award Number: P20GM144230

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/20/2022

PERIOD OF PERFORMANCE END DATE: 01/31/2027

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