Tuesday, September 16, 2025 9/16/2025

Integrative Center for Precision Nutrition and Human Health

Award Number: P20GM139753
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/20/2022
PERIOD OF PERFORMANCE END DATE: 01/31/2027

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Integrative Center for Precision Nutrition and Human Health - PROJECT SUMMARY Precision nutrition is a new and now integral component of precision medicine that exploits differences in how dietary components are absorbed, metabolized and converted to energy, and in how that energy is utilized, resulting in widely varying dietary and nutrient requirements. In Hawaii, culture and customs influence dietary preferences and economic disparities affect food access, further amplifying differences in nutritional needs and individual responses to dietary components. Recognizing the innovative new opportunities available through precision nutrition approaches, and the transformative potential for impactful nutritional health benefits, particularly to the indigenous and underserved people of Hawaii, the University of Hawaii proposes to establish a multicomponent center that enables multidisciplinary research with the thematic focus of Precision Nutrition. The overall goal of this Centers of Biomedical Research Excellence (COBRE) Phase I proposal is the creation of an Integrative Center for Precision Nutrition and Human Health at the University of Hawai’i at Manoa (UHM), ‘integrative’ in that it will encompass the interface between precision nutrition research and human health outcomes. Our objectives are to build the foundation needed to grow a cadre of future leaders and mentors in precision nutrition, the fruits of their efforts feeding the attainment of positive impacts on human health, and to broadly disseminate and implement healthful strategies and interventions, nourishing the sustainability of this Precision Nutrition COBRE. The overall goal of creating a Precision Nutrition COBRE that fosters excellence in research, career development, and community health, will be achieved through the following three Specific Aims: Aim 1: To create an Integrative Center for Precision Nutrition and Human Health founded on impactful, scientifically rigorous research, education and training; built around a cadre of promising future scientific leaders; and fostered by outstanding individually-crafted, team-facilitated mentoring and career development activities. Aim 2: To provide research investigators education and training in cutting edge technologies and access to state-of-the-art research Core Facilities, integrating these resources with other research and training programs and facilities at UH, with community-based research in Hawaii, and with the IDeA network across the nation. Aim 3: To promote development of strong collaborative relationships between academic researchers and the community, based on culturally sensitive approaches, with the goal of achieving tangible health benefits for all. Through the combined efforts of Precision Nutrition COBRE researchers and our community partners, with the guidance of the Community Engagement and Outreach Core, we will collaboratively advance precision nutrition, share and disseminate beneficial and healthful strategies and interventions and positive outcomes throughout the community, the State and beyond. The long term goal of the Center is to promote health through the advantages of precision nutrition, implemented across the community and beyond, thereby producing lasting, far-reaching positive impacts on human health.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $2,136,244 )
2025	2025	UNIVERSITY OF HAWAII	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Biomedical Research and Research Training	000	4	7/10/2025	NON-COMPETING CONTINUATION	$2,136,244
														Subtotal = $2,136,244

Issue Date FY: 2024 ( Subtotal = $2,136,244 )
2024	2024	UNIVERSITY OF HAWAII	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Biomedical Research and Research Training	001	3	7/22/2024	NON-COMPETING CONTINUATION	$213,625
2024	2024	UNIVERSITY OF HAWAII	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Biomedical Research and Research Training	000	3	2/14/2024	NON-COMPETING CONTINUATION	$1,922,619
														Subtotal = $2,136,244

Issue Date FY: 2023 ( Subtotal = $2,308,472 )
2023	2023	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Biomedical Research and Research Training	001	2	2/24/2023	NON-COMPETING CONTINUATION	$0
2023	2023	UNIVERSITY OF HAWAII	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Biomedical Research and Research Training	003	2	9/20/2023	NON-COMPETING CONTINUATION	$0
2023	2023	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Biomedical Research and Research Training	000	2	2/8/2023	NON-COMPETING CONTINUATION	$2,142,800
2023	2023	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Biomedical Research and Research Training	002	2	7/6/2023	SUPPLEMENT FOR EXPANSION	$165,672
														Subtotal = $2,308,472

Issue Date FY: 2022 ( Subtotal = $2,443,468 )
2022	2022	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Biomedical Research and Research Training	000	1	3/18/2022	NEW	$2,443,468
														Subtotal = $2,443,468

Grand Total All Awards = $9,024,428

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Integrative Center for Precision Nutrition and Human Health

Award Number: P20GM139753

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/20/2022

PERIOD OF PERFORMANCE END DATE: 01/31/2027

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