Saturday, December 20, 2025 12/20/2025

Vermont Center for Cardiovascular and Brain Health

Award Number: P20GM135007
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/06/2020
PERIOD OF PERFORMANCE END DATE: 05/31/2026

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Vermont Center for Cardiovascular and Brain Health - PROJECT SUMMARY Cardiovascular disease is the #1 cause of mortality in the United States and stroke is the #5 cause. Stroke is also the #1 cause of disability, and it, along with covert neurovascular disease including small vessel disease of the brain, leads to Vascular Cognitive Impairment and Dementia (VCID). Each year 800,000 Americans have a stroke and 720,000 Americans have myocardial infarction. There will be 75 million people with dementia by 2030 and 131 million by 2050. Direct annual costs of cardiovascular disease and stroke are $318 billion and dementia $277 billion. The American Heart Association issued a Presidential Advisory in 2017 highlighting the central role of cardiovascular health to brain health and cognitive function. Much of VCID is driven by increases in covert stroke and small vessel disease of the brain, research areas of expertise for the PIs of this application. To address these issues, this University of Vermont (UVM) Center on Cardiovascular and Brain Health (VCCBH) will leverage NIH funding and institutional commitment to convene multidisciplinary researchers across career stages to determine causes and suggest optimal treatments for cardiovascular and neurovascular disease, including stroke and VCID. We have selected four junior faculty (Project Directors, PDs), from three departments and two UVM colleges, through a rigorous selection process. The VCCBH will support the PDs' transition to independence using a Strategic Mentoring Initiative (SMI), Faculty Development Program (FDP), and assistance and education from two new Core facilities. The SMI will employ multidisciplinary Mentor Teams, including Peer Mentors. The FDP will comprise several educational programs highlighted by an annual 2-Day Research Symposium, and an impactful Pilot Grant program (supported by institutional commitments) that will provide $200,000 to four interdisciplinary research teams of junior faculty. We will establish two new Core facilities: Study Design and Molecular Epidemiology, and Customized Physiology and Imaging. A pipeline of new project directors will be developed from a pool of 19 current candidates and five new junior faculty, who will be recruited with committed institutional support. Capstones of the Center will include continual quality evaluation, clear communication and commitment to diversity. By the completion of Phase I of funding, the Center will be on a strong path to sustainability in research excellence.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2024	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	000	5	12/17/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	001	5	3/27/2025	NON-COMPETING CONTINUATION	$0
2025	2024	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	000	5	12/11/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $2,307,350 )
2024	2024	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	003	5	7/17/2024	NON-COMPETING CONTINUATION	$2,307,350
2024	2023	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	002	4	6/14/2024	NON-COMPETING CONTINUATION	$0
2024	2023	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	001	4	12/21/2023	SUPPLEMENT FOR EXPANSION	$0
2024	2023	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	000	4	12/12/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,307,350

Issue Date FY: 2023 ( Subtotal = $3,240,256 )
2023	2023	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	003	4	9/15/2023	SUPPLEMENT FOR EXPANSION	$660,479
2023	2023	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	001	4	7/6/2023	NON-COMPETING CONTINUATION	$2,307,350
2023	2023	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT STREET	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	002	4	8/29/2023	SUPPLEMENT FOR EXPANSION	$272,427
2023	2022	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT ST	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	000	3	12/19/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,240,256

Issue Date FY: 2022 ( Subtotal = $2,315,833 )
2022	2022	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT ST	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	000	3	6/7/2022	NON-COMPETING CONTINUATION	$2,315,833
														Subtotal = $2,315,833

Issue Date FY: 2021 ( Subtotal = $2,322,405 )
2021	2021	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT ST	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	003	2	7/8/2021	NON-COMPETING CONTINUATION	$2,322,405
2021	2020	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT ST	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	002	1	7/7/2021	NEW	$0
2021	2020	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT ST	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	000	1	12/3/2020	NEW	$0
2021	2020	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT ST	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	001	1	5/6/2021	NEW	$0
														Subtotal = $2,322,405

Issue Date FY: 2020 ( Subtotal = $2,604,345 )
2020	2020	UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE	85 S PROSPECT ST	BURLINGTON	VT	05405	CHITTENDEN	USA	Biomedical Research and Research Training	000	1	8/6/2020	NEW	$2,604,345
														Subtotal = $2,604,345

Grand Total All Awards = $12,790,189

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Vermont Center for Cardiovascular and Brain Health

Award Number: P20GM135007

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/06/2020

PERIOD OF PERFORMANCE END DATE: 05/31/2026

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