Monday, September 15, 2025 9/15/2025

Metabolic Basis of Disease - Phase 2

Award Number: P20GM135002
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/01/2020
PERIOD OF PERFORMANCE END DATE: 07/31/2030

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Metabolic Basis of Disease - Phase 2 - Project Summary: The overall goal of this Phase 2 COBRE is to facilitate the growth of young intellectual talent and strengthen and enhance the scientific infrastructure that will promote biomedical research discoveries that will enhance our understanding of the metabolic aspects of different diseases. Specifically, we have identified three research project leaders (RPLs) with scientific interests in different, but complementary aspects of disease research. Each Research Project focuses on the metabolic aspect of a disease (HFpEF/heart failure with preserved ejection fractions, HCC/hepatocellular carcinoma, and undernutrition and iron metabolism). Despite the diversity in tissues and diseases of interest, each project strongly fits into Pennington Biomedical’s general mission, to discover the triggers of chronic diseases through innovative research that improves human health across the lifespan. In all aspects of our Phase 2 center, we are committed to prioritizing the promotion of diverse perspectives. Within this Metabolic Basis of Disease (MBD) COBRE proposal, we established two scientific cores in Phase 1. The Preclinical Research Core brings together strengths from our Comparative Biology Core, Animal Models and Behavior Core, and Genetically Engineered Models Core. The Molecular Mechanisms core integrates aspects of our Genomic Cores and Cell Biology Bioimaging Core and provides mentoring and technical support for the RPLs and PBRC faculty. In Phase 2, this core will have a stronger emphasis on bioinformatics and new leadership. We will also establish a new Pilot and Feasibility Program to identify new RPLs and promote metabolic basis of disease research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $2,197,409 )
2025	2025	PENNINGTON BIOMEDICAL RESEARCH CENTER	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	001	6	7/23/2025	COMPETING CONTINUATION	$2,197,409
2025	2024	PENNINGTON BIOMEDICAL RESEARCH CENTER	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	000	5	7/17/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,197,409

Issue Date FY: 2024 ( Subtotal = $2,159,896 )
2024	2024	LSU PENNINGTON	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	004	5	7/12/2024	NON-COMPETING CONTINUATION	$0
2024	2024	LSU PENNINGTON	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	003	5	5/15/2024	NON-COMPETING CONTINUATION	$215,989
2024	2024	LSU PENNINGTON	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	005	5	8/14/2024	NON-COMPETING CONTINUATION	$0
2024	2024	LSU PENNINGTON	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	002	5	1/24/2024	NON-COMPETING CONTINUATION	$1,943,907
2024	2023	LSU PENNINGTON	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	001	4	12/20/2023	NON-COMPETING CONTINUATION	$0
2024	2023	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	000	4	11/6/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,159,896

Issue Date FY: 2023 ( Subtotal = $2,399,052 )
2023	2023	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	002	4	2/28/2023	NON-COMPETING CONTINUATION	$2,159,896
2023	2023	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	003	4	8/31/2023	SUPPLEMENT FOR EXPANSION	$239,156
2023	2022	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	000	3	11/15/2022	NON-COMPETING CONTINUATION	$0
2023	2022	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	001	3	12/1/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,399,052

Issue Date FY: 2022 ( Subtotal = $2,159,896 )
2022	2022	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	002	3	5/17/2022	NON-COMPETING CONTINUATION	$215,989
2022	2022	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	001	3	2/8/2022	NON-COMPETING CONTINUATION	$1,943,907
2022	2022	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	003	3	7/14/2022	NON-COMPETING CONTINUATION	$0
2022	2021	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	000	2	12/3/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,159,896

Issue Date FY: 2021 ( Subtotal = $2,644,367 )
2021	2021	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	001	2	2/12/2021	NON-COMPETING CONTINUATION	$216,469
2021	2021	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	003	2	8/13/2021	SUPPLEMENT FOR EXPANSION	$212,164
2021	2021	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	004	2	8/20/2021	NON-COMPETING CONTINUATION	$0
2021	2021	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	000	2	1/25/2021	NON-COMPETING CONTINUATION	$1,948,227
2021	2021	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	002	2	8/3/2021	SUPPLEMENT FOR EXPANSION	$267,507
														Subtotal = $2,644,367

Issue Date FY: 2020 ( Subtotal = $2,471,896 )
2020	2020	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	001	1	9/14/2020	NEW	$0
2020	2020	LOUISIANA STATE UNIVERSITY SYSTEM	6400 PERKINS RD	BATON ROUGE	LA	70808	EAST BATON ROUGE	USA	Biomedical Research and Research Training	000	1	2/26/2020	NEW	$2,471,896
														Subtotal = $2,471,896

Grand Total All Awards = $14,032,516

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Metabolic Basis of Disease - Phase 2

Award Number: P20GM135002

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/01/2020

PERIOD OF PERFORMANCE END DATE: 07/31/2030

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