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Mississippi Center of Excellence in Perinatal Research, Phase 2:Supplement: Hypertension in PCOS women: Interplay between Biological and Societal Factors.

Award Number: P20GM121334
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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MISSISSIPPI CENTER OF EXCELLENCE IN PERINATAL RESEARCH SUMMARY This proposal is to continue funding in Phase 2 to advance and sustain the Mississippi Center of Excellence in Perinatal Research (MS CEPR) COBRE at the University of Mississippi Medical Center (UMMC). Perinatal research encompasses the study of disease states that have their etiology during gestation and early post-natal development that result in long term consequences in the mother and offspring across their lifespans. Studies during Phase 1 focused on the integrative relationships and health disparities among adverse pregnancy, pregnancy outcomes and developmental programming of diseases in human and animal studies by 12 investigators (2 clinicians, 8 women, and 5 under-represented minorities), who secured > $4.6 million in federal funding (>$12 million total) and contributed 115 publications. The Center grew from 17 investigators to 51 in 5 basic science and 3 clinical departments. Development and support for the MS CEPR cores also allowed 160 additional local and extramural investigators to obtain 75 PHS/non-PHS grants. Our longterm goal is to develop an internationally recognized MS CEPR dedicated to improving the lives of women and their offspring, especially in Mississippi, through discovery, innovation, and translation to prevent and reduce death and disability from perinatally-induced diseases. The major goal of Phase 2 of this COBRE is to further advance the MS CEPR to provide infrastructure and capacity for a multidisciplinary, diverse group of basic, clinical and population scientists working on the common synergistic theme of perinatal diseases and health disparities and to facilitate their collaborations. Continuing to support the MS CEPR will provide a diverse group of Research Project and Pilot Project investigators with outstanding mentors and the necessary research core services to accelerate acquisition of extramural funding and provide career development programs to develop the junior investigators into highly productive, independent investigators, and the senior investigators who are changing research direction to conduct synergistic research on the common theme of perinatal research and developmental programming of disease that is so important for our population in Mississippi. The goals of the Center are achieved by providing a stimulating mentoring environment, strengthening research capacity and capabilities, increasing diversity of our researchers and study populations, and enhancing the research infrastructure at UMMC.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	000	8	10/18/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $2,625,042 )
2024	2024	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	002	8	6/25/2024	SUPPLEMENT FOR EXPANSION	$304,153
2024	2024	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	001	8	5/27/2024	NON-COMPETING CONTINUATION	$2,320,889
2024	2023	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	000	7	1/10/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,625,042

Issue Date FY: 2023 ( Subtotal = $2,323,086 )
2023	2023	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	003	7	7/4/2023	NON-COMPETING CONTINUATION	$2,323,086
2023	2022	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	001	6	2/2/2023	COMPETING CONTINUATION	$925,626
2023	2022	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	002	6	2/20/2023	COMPETING CONTINUATION	$0
2023	2021	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	000	5	2/2/2023	NON-COMPETING CONTINUATION	-$925,626
														Subtotal = $2,323,086

Issue Date FY: 2022 ( Subtotal = $2,325,000 )
2022	2022	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	002	6	8/3/2022	COMPETING CONTINUATION	$2,325,000
2022	2021	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	001	5	8/2/2022	NON-COMPETING CONTINUATION	$0
2022	2021	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	000	5	12/8/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,325,000

Issue Date FY: 2021 ( Subtotal = $2,325,000 )
2021	2021	UNIVERSITY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	000	5	6/23/2021	NON-COMPETING CONTINUATION	$2,325,000
														Subtotal = $2,325,000

Issue Date FY: 2020 ( Subtotal = $2,589,382 )
2020	2020	UNIVERISTY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	000	4	6/11/2020	NON-COMPETING CONTINUATION	$2,325,000
2020	2020	UNIVERISTY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	001	4	9/7/2020	NON-COMPETING CONTINUATION	$0
2020	2020	UNIVERISTY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	002	4	9/7/2020	SUPPLEMENT FOR EXPANSION	$264,382
														Subtotal = $2,589,382

Issue Date FY: 2019 ( Subtotal = $2,325,000 )
2019	2019	UNIVERISTY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	002	3	7/30/2019	NON-COMPETING CONTINUATION	$2,325,000
2019	2018	UNIVERISTY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	001	2	1/21/2019	NON-COMPETING CONTINUATION	$0
2019	2018	UNIVERISTY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	000	2	12/5/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,325,000

Issue Date FY: 2018 ( Subtotal = $2,325,000 )
2018	2018	UNIVERISTY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	000	2	5/31/2018	NON-COMPETING CONTINUATION	$2,325,000
														Subtotal = $2,325,000

Issue Date FY: 2017 ( Subtotal = $2,283,522 )
2017	2017	UNIVERISTY OF MISSISSIPPI MEDICAL CENTER	2500 N STATE ST	JACKSON	MS	39216	HINDS	USA	Biomedical Research and Research Training	000	1	6/8/2017	NEW	$2,283,522
														Subtotal = $2,283,522

Grand Total All Awards = $19,121,032

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Mississippi Center of Excellence in Perinatal Research, Phase 2:Supplement: Hypertension in PCOS women: Interplay between Biological and Societal Factors.

Award Number: P20GM121334

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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