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Harnessing Movement Variability to Treat and Prevent Motor Related Disorders

Award Number: P20GM109090
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/01/2014
PERIOD OF PERFORMANCE END DATE: 07/31/2025

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Harnessing Movement Variability to Treat and Prevent Motor Related Disorders - PROJECT SUMMARY In COBRE Phase I we established the Center for Research in Human Movement Variability (MOVCENTR) allowing the development of a strong critical mass of investigators and tremendous growth in terms of research infrastructure with world class facilities and resources such as the Biomechanics Research Building with its associated technologies and methodologies as well as the building’s upcoming expansion. In COBRE Phase II, we build on these foundational successes to maximize the likelihood of achieving an independent, sustainable, thematic, interdisciplinary center. We aim to further strengthen the infrastructure and expertise base to explore the mechanisms of human movement variability in order to treat and prevent motor related disorders. Therefore, we propose to establish three new research cores, the Movement Analysis Core, the Nonlinear Analysis Core, and the Machining and Prototyping Core. We also aim to expand the critical mass of funded investigators supporting research in human movement variability. As such we propose four research projects that will be carried out under the Center’s umbrella. The project titles are: (1) The influence of prosthesis use on cortical activation and movement variability, (2) Longitudinal study of gait variability to predict falls in Parkinson disease, (3) Exoskeleton optimization for reducing gait variability in patients with Peripheral Artery Disease, and (4) Variability and specificity in reactive stabilization movements to diverse slip perturbations. These projects are led by strong junior investigators paired with senior clinical NIH-funded scientists as scientific advisors. Such a mentoring relationship is unique and has worked very well in enhancing the efficiency and quality of the clinical and translational research that is conducted in each research project under our thematic scientific focus.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	000	10	12/11/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $2,002,193 )
2023	2023	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	002	10	9/4/2023	NON-COMPETING CONTINUATION	$2,002,193
2023	2022	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	001	9	6/14/2023	NON-COMPETING CONTINUATION	$0
2023	2022	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	000	9	3/7/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,002,193

Issue Date FY: 2022 ( Subtotal = $2,036,407 )
2022	2022	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	002	9	9/22/2022	NON-COMPETING CONTINUATION	$2,036,407
2022	2021	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	001	8	9/22/2022	NON-COMPETING CONTINUATION	$0
2022	2021	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	000	8	3/21/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,036,407

Issue Date FY: 2021 ( Subtotal = $2,070,473 )
2021	2021	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	002	8	8/27/2021	NON-COMPETING CONTINUATION	$2,070,473
2021	2020	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	001	7	4/20/2021	NON-COMPETING CONTINUATION	$0
2021	2020	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	000	7	10/15/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,070,473

Issue Date FY: 2020 ( Subtotal = $2,119,859 )
2020	2020	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	004	7	8/21/2020	NON-COMPETING CONTINUATION	$2,119,859
2020	2019	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	003	6	8/21/2020	COMPETING CONTINUATION	$0
2020	2019	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	001	6	12/19/2019	COMPETING CONTINUATION	$279,600
2020	2019	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	002	6	1/24/2020	COMPETING CONTINUATION	$0
2020	2018	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	000	5	12/19/2019	NON-COMPETING CONTINUATION	-$279,600
														Subtotal = $2,119,859

Issue Date FY: 2019 ( Subtotal = $2,163,462 )
2019	2019	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	003	6	8/28/2019	COMPETING CONTINUATION	$2,163,462
2019	2018	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	001	5	1/25/2019	NON-COMPETING CONTINUATION	$0
2019	2018	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	002	5	8/27/2019	NON-COMPETING CONTINUATION	$0
2019	2018	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	000	5	11/29/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,163,462

Issue Date FY: 2018 ( Subtotal = $1,965,319 )
2018	2018	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	000	5	5/23/2018	NON-COMPETING CONTINUATION	$1,965,319
														Subtotal = $1,965,319

Issue Date FY: 2017 ( Subtotal = $2,009,448 )
2017	2017	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	001	4	7/10/2017	NON-COMPETING CONTINUATION	$200,946
2017	2017	UNIVERSITY OF NEBRASKA	6001 DODGE ST EAB 209	OMAHA	NE	68182	DOUGLAS	USA	Biomedical Research and Research Training	000	4	5/1/2017	NON-COMPETING CONTINUATION	$1,808,502
														Subtotal = $2,009,448

Issue Date FY: 2016 ( Subtotal = $2,052,054 )
2016	2016	UNIVERSITY OF NEBRASKA AT OMAHA	POST OFFICE BOX 688	OMAHA	NE	68101	DOUGLAS	USA	Biomedical Research and Research Training	000	3	4/15/2016	NON-COMPETING CONTINUATION	$2,052,054
														Subtotal = $2,052,054

Issue Date FY: 2015 ( Subtotal = $2,034,269 )
2015	2015	UNIVERSITY OF NEBRASKA AT OMAHA	POST OFFICE BOX 688	OMAHA	NE	68101	DOUGLAS	USA	Biomedical Research and Research Training	000	2	4/21/2015	NON-COMPETING CONTINUATION	$2,034,269
														Subtotal = $2,034,269

Issue Date FY: 2014 ( Subtotal = $2,027,319 )
2014	2014	UNIVERSITY OF NEBRASKA AT OMAHA	POST OFFICE BOX 688	OMAHA	NE	68101	DOUGLAS	USA	Biomedical Research and Research Training	000	1	8/1/2014	NEW	$2,027,319
														Subtotal = $2,027,319

Grand Total All Awards = $20,480,803

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Harnessing Movement Variability to Treat and Prevent Motor Related Disorders

Award Number: P20GM109090

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/01/2014

PERIOD OF PERFORMANCE END DATE: 07/31/2025

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