Tuesday, November 4, 2025 11/4/2025

The Delaware Comprehensive Sickle Cell Research Center

Award Number: P20GM109021
ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/01/2014
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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The Delaware Comprehensive Sickle Cell Research Center - The Delaware Sickle Cell Disease (SCD) COBRE is a multidisciplinary center of biomedical research excellence with a thematic focus on translational and clinical research in sickle cell disease. Building on a biomedical and clinical research infrastructure developed through COBRE Phase 1 funding, and the successful recruitment of several promising early career investigators, the DE SCD COBRE is submitting a competitive renewal application to continue capacity-building and innovative research. In Phase 1, the DE SCD COBRE contributed to more than $13 million in new funding in Delaware. Integration of the DE SCD COBRE within the Delaware IDeA network continues to be integral to both the successful recruitment and training of early career investigators, as well as pilot funding. In this Phase 2 COBRE submission, the DE SCD COBRE presents a new mentoring model, a new pilot funding program, a new Clinical Research and Data Informatics Core and four new target investigators. Each of these new additions builds on success in Phase 1 and is responsive to areas of strength and growth. Additionally, we are developing a multidisciplinary and systematic approach to study the influence of targeted interventions in patients with SCD. We will evaluate biomarkers for severe SCD co-morbidities (Project 4), engage our patients to improve care (Project 1, 2, and 3) and explore tools to improve self-efficacy among health care providers (Project 1) and patients (Project 1, 2, and 3). Central to all aspects of the Delaware Sickle Cell Research Program is the overarching Center hypothesis that effective management of a common, congenital, multi-system disease requires comprehensive investigations spanning the biological and medical factors that impact both the severity of the disease and the efficacy of interventions.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $2,128,939 )
2025	2025	THE NEMOURS FOUNDATION	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	001	10	9/9/2025	NON-COMPETING CONTINUATION	$2,128,939
2025	2024	THE NEMOURS FOUNDATION	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	9	12/5/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,128,939

Issue Date FY: 2024 ( Subtotal = $2,128,939 )
2024	2024	THE NEMOURS FOUNDATION	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	001	9	8/29/2024	NON-COMPETING CONTINUATION	$2,128,939
2024	2023	THE NEMOURS FOUNDATION	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	8	3/22/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,128,939

Issue Date FY: 2023 ( Subtotal = $2,090,033 )
2023	2023	THE NEMOURS FOUNDATION	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	002	8	8/22/2023	NON-COMPETING CONTINUATION	$2,090,033
2023	2022	THE NEMOURS FOUNDATION	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	7	3/21/2023	NON-COMPETING CONTINUATION	$0
2023	2022	THE NEMOURS FOUNDATION	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	001	7	5/11/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,090,033

Issue Date FY: 2022 ( Subtotal = $2,092,666 )
2022	2022	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	002	7	7/13/2022	NON-COMPETING CONTINUATION	$2,092,666
2022	2021	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	001	6	4/19/2022	COMPETING CONTINUATION	$337,012
2022	2018	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	5	4/19/2022	NON-COMPETING CONTINUATION	-$337,012
														Subtotal = $2,092,666

Issue Date FY: 2021 ( Subtotal = $2,064,535 )
2021	2021	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	002	6	8/6/2021	COMPETING CONTINUATION	$2,064,535
2021	2018	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	5	3/23/2021	NON-COMPETING CONTINUATION	$0
2021	2018	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	001	5	8/5/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,064,535

Issue Date FY: 2020 ( Subtotal = $0 )
2020	2018	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	5	4/23/2020	NON-COMPETING CONTINUATION	$0
2020	2018	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	001	5	7/13/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2019 ( Subtotal = $0 )
2019	2018	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	002	5	9/20/2019	NON-COMPETING CONTINUATION	$0
2019	2018	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	5	12/12/2018	NON-COMPETING CONTINUATION	$0
2019	2018	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	001	5	1/7/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2018 ( Subtotal = $1,866,125 )
2018	2018	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	5	5/18/2018	NON-COMPETING CONTINUATION	$1,866,125
														Subtotal = $1,866,125

Issue Date FY: 2017 ( Subtotal = $1,929,240 )
2017	2017	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	001	4	7/10/2017	NON-COMPETING CONTINUATION	$192,925
2017	2017	NEMOURS FOUNDATION, THE	1600 ROCKLAND RD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	4	4/24/2017	NON-COMPETING CONTINUATION	$1,736,315
														Subtotal = $1,929,240

Issue Date FY: 2016 ( Subtotal = $1,981,459 )
2016	2016	ALFRED I DUPONT HOSP FOR CHILD NCC-W OF THE NEMOURS FDN	1600 ROCKLAND ROAD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	3	5/16/2016	NON-COMPETING CONTINUATION	$1,981,459
														Subtotal = $1,981,459

Issue Date FY: 2015 ( Subtotal = $2,015,028 )
2015	2015	ALFRED I DUPONT HOSP FOR CHILD NCC-W OF THE NEMOURS FDN	1600 ROCKLAND ROAD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	2	4/17/2015	NON-COMPETING CONTINUATION	$2,015,028
														Subtotal = $2,015,028

Issue Date FY: 2014 ( Subtotal = $2,369,782 )
2014	2014	ALFRED I DUPONT HOSP FOR CHILD NCC-W OF THE NEMOURS FDN	1600 ROCKLAND ROAD	WILMINGTON	DE	19803	NEW CASTLE	USA	Biomedical Research and Research Training	000	1	7/25/2014	NEW	$2,369,782
														Subtotal = $2,369,782

Grand Total All Awards = $20,666,746

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The Delaware Comprehensive Sickle Cell Research Center

Award Number: P20GM109021

ORGANIZATION: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/01/2014

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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