Monday, November 17, 2025 11/17/2025

All of Us Southern California Consortium (AoUSCC)

Award Number: OT2OD036428
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: OTHER
PERIOD OF PERFORMANCE START DATE: 05/01/2024
PERIOD OF PERFORMANCE END DATE: 07/31/2026

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All of Us Southern California Consortium (AoUSCC) - The overall goal of the All of Us Southern California Consortium, led by the University of California, Irvine, is to engage, recruit, and retain participants from the Southern California population with the goal to participate in the scientific mission of the All of Us Research Program, including participation in Partnered Research Studies (PRS) such as the Eyes on Health ocular imaging study. We have assembled a multidisciplinary team with significant scientific strength, experience, and motivation to be one of the most effective and efficient All of Us consortia nationwide. AoUSCC strives to promote access to health data and tools for participants, citizen scientists, and researchers to make queries and obtain impactful results using the All of Us research data in a privacy-preserving manner for the advancement of science in disease etiology and progression, health data research, data access, breakthroughs in artificial intelligence and machine learning, and precision medicine. We continue our work in promoting the data from the All of Us Research Hub to train future biomedical scientists. The AoUSCC goals for Year 2 guided by national All of Us priorities include: 1) Maintain regulatory requirements and develop processes and timelines for completion. 2) Achieve All of Us adult enrollment goals in direct support of PRS enrollment and expectations, including those for the Eyes on Health. 3) Ensure facilitated participation of existing potential and existing AoU participants for enrollment and retention. 4) Achieve electronic health record expectations, metrics, and provide twice-yearly electronic health records data transfers to the Data Research Center from UC Irvine. 5) Achieve performance metrics for sample quality related to biospecimens. AoUSCC will work with the Program to advance the National Institutes of Health’s mission to deliver results that matter to the American public. AoUSCC will continue to work with the national All of Us leadership to focus on scientifically valid and measurable health outcomes.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $887,147 )
2025	2025	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	008	1	7/30/2025	SUPPLEMENT FOR EXPANSION	$837,000
2025	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	002	1	4/10/2025	NEW	$0
2025	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	005	1	7/1/2025	SUPPLEMENT FOR EXPANSION	$0
2025	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	007	1	7/30/2025	SUPPLEMENT FOR EXPANSION	$0
2025	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	006	1	7/30/2025	NEW	$0
2025	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	004	1	7/1/2025	NEW	$0
2025	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	000	1	11/1/2024	SUPPLEMENT FOR EXPANSION	$50,147
2025	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	001	1	1/27/2025	NEW	$0
2025	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	003	1	4/10/2025	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $887,147

Issue Date FY: 2024 ( Subtotal = $4,250,000 )
2024	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	001	1	9/11/2024	SUPPLEMENT FOR EXPANSION	$250,000
2024	2024	UNIVERSITY OF CALIFORNIA IRVINE	160 ALDRICH HALL	IRVINE	CA	92697	ORANGE	USA	21st Century Cures Act - Precision Medicine Initiative	000	1	4/30/2024	NEW	$4,000,000
														Subtotal = $4,250,000

Grand Total All Awards = $5,137,147

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All of Us Southern California Consortium (AoUSCC)

Award Number: OT2OD036428

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: OTHER

PERIOD OF PERFORMANCE START DATE: 05/01/2024

PERIOD OF PERFORMANCE END DATE: 07/31/2026

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