Wednesday, October 1, 2025 10/1/2025

SPARC Engagement Plan with the Common Fund Data Ecosystem

Award Number: OT2OD032619
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: OTHER
PERIOD OF PERFORMANCE START DATE: 09/23/2021
PERIOD OF PERFORMANCE END DATE: 03/22/2027

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SPARC Engagement Plan with the Common Fund Data Ecosystem - Modified Project Summary/Abstract Section The SPARC Knowledge Management and Curation Core (K-Core) is engaged with the Common Fund Data Ecosystem (CFDE) through a number of activities: 1) Continue to actively participate in and engage with CFDE; 2) Continue to participate in working groups and carry out Working Groups’ recommendations; 3) Contribute SPARC (i) resource metadata to C2M2 [2], (ii) develop and maintain necessary services to support data within the CFDE Portal (e.g. DRS services), and (iii) ensure users are able to access SPARC data in the cloud; and 4) participate in other CFDE projects as needed. Metadata and asset ingestion into the data resource portal will include the production of C2M2 data submission manifests and the upload of these manifests to the CFDE Workbench including specification of ontology mappings. This will also entail maintenance of the SPARC data submission export pipeline to support updates in SPARC metadata and any updates to the CFDE submission process. As the SPARC DRC is now also supporting data publication through other initiatives (e.g. NIH HEAL) we will also work with CFDE to determine best ways to annotate these data assets that have begun to be published. Additional asset ingestion into the data resource portal will continue to include knowledge graph assertions from the SPARC Connectivity knowledge graph (SCKAN). In addition, we will pilot the contribution of assertions from the Functional Connectivity Map – which is focused on biological compartments, their connectivity, their protein and small molecule constituents, as well as related biophysical models that study related processes (e.g., fluid flow, drug transport). This FC Map currently contains knowledge for ~300 drugs and~900 related gene products, and explicitly represents knowledge about relevant tissues, cells, fluids, protein and small molecules. We will generate RDF models of FC Map metadata, leveraging semantic standards adopted by the Ontology Working Group for integration with CFDE.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $349,999 )
2025	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	001	1	9/10/2025	SUPPLEMENT FOR EXPANSION	$349,999
2025	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	000	1	9/10/2025	NEW	$0
														Subtotal = $349,999

Issue Date FY: 2024 ( Subtotal = $299,972 )
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	001	1	9/9/2024	SUPPLEMENT FOR EXPANSION	$299,972
2024	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	002	1	9/12/2024	NEW	$0
2024	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	000	1	9/9/2024	NEW	$0
														Subtotal = $299,972

Issue Date FY: 2023 ( Subtotal = $955,891 )
2023	2023	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	001	1	9/20/2023	SUPPLEMENT FOR EXPANSION	$955,891
2023	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DRIVE	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	000	1	9/19/2023	NEW	$0
														Subtotal = $955,891

Issue Date FY: 2022 ( Subtotal = $803,352 )
2022	2022	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	001	1	9/15/2022	SUPPLEMENT FOR EXPANSION	$803,352
2022	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	000	1	9/14/2022	NEW	$0
														Subtotal = $803,352

Issue Date FY: 2021 ( Subtotal = $818,322 )
2021	2021	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Trans-NIH Research Support	000	1	9/22/2021	NEW	$818,322
														Subtotal = $818,322

Grand Total All Awards = $3,227,536

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SPARC Engagement Plan with the Common Fund Data Ecosystem

Award Number: OT2OD032619

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: OTHER

PERIOD OF PERFORMANCE START DATE: 09/23/2021

PERIOD OF PERFORMANCE END DATE: 03/22/2027

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